Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein
Submitted name:

Integrin

Gene
N/A
Organism
Geodia cydonium (Sponge)
Status
Unreviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

GO - Biological processi

Keywordsi

Molecular functionIntegrinUniRule annotationSAAS annotationImported, ReceptorUniRule annotationSAAS annotation
Biological processCell adhesionUniRule annotationSAAS annotation

Names & Taxonomyi

Protein namesi
Submitted name:
IntegrinImported
OrganismiGeodia cydonium (Sponge)Imported
Taxonomic identifieri6047 [NCBI]
Taxonomic lineageiEukaryotaMetazoaPoriferaDemospongiaeHeteroscleromorphaTetractinellidaAstrophorinaGeodiidaeGeodia

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei1034 – 1060HelicalUniRule annotationAdd BLAST27

Keywords - Cellular componenti

Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 17UniRule annotationAdd BLAST17
ChainiPRO_500142566018 – 1086UniRule annotationAdd BLAST1069

Structurei

3D structure databases

ProteinModelPortaliO18428
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Repeati27 – 97FG-GAPPROSITE-ProRule annotationAdd BLAST71
Repeati105 – 151FG-GAPPROSITE-ProRule annotationAdd BLAST47
Repeati172 – 228FG-GAPPROSITE-ProRule annotationAdd BLAST57
Repeati285 – 346FG-GAPPROSITE-ProRule annotationAdd BLAST62
Repeati347 – 404FG-GAPPROSITE-ProRule annotationAdd BLAST58
Repeati415 – 476FG-GAPPROSITE-ProRule annotationAdd BLAST62
Domaini461 – 888Integrin_alpha2InterPro annotationAdd BLAST428

Sequence similaritiesi

Belongs to the integrin alpha chain family.UniRule annotationSAAS annotation

Keywords - Domaini

RepeatSAAS annotation, SignalUniRule annotation, Transmembrane, Transmembrane helixUniRule annotationSAAS annotation

Family and domain databases

Gene3Di2.130.10.130, 1 hit
InterProiView protein in InterPro
IPR013517 FG-GAP
IPR013519 Int_alpha_beta-p
IPR000413 Integrin_alpha
IPR013649 Integrin_alpha-2
IPR028994 Integrin_alpha_N
IPR032695 Integrin_dom_sf
PfamiView protein in Pfam
PF01839 FG-GAP, 1 hit
PF08441 Integrin_alpha2, 1 hit
PRINTSiPR01185 INTEGRINA
SMARTiView protein in SMART
SM00191 Int_alpha, 4 hits
SUPFAMiSSF69179 SSF69179, 3 hits
PROSITEiView protein in PROSITE
PS51470 FG_GAP, 6 hits

Sequencei

Sequence statusi: Complete.

O18428-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MTRTLLLLAA CLAAAHCIKN IDLQQPIVRT APEELNKDGY FGYSLVLHQK
60 70 80 90 100
VVSTGFEQSL QNTYLIVGAP NGTRSNSAEK NTGFVYECRL AQNGQCTRIP
110 120 130 140 150
ALSDDTADSN LEDKEGQFMG GALASNGDRF MACGHRYVNF NPSNTNTRSV
160 170 180 190 200
YGRCFYADRS LNNFQEFQPC EGVGRKITQS LGVCPAGMSA VVAETSDGTD
210 220 230 240 250
HLALGAPGSY LLKRIVIRST PGRVDSNRFQ PYDLTGEKHI RVGKETVSLR
260 270 280 290 300
ASFRSTNVED FATSVPRLGS YFGAVHIIRN DDTLQMISQN LVGDQMGEYY
310 320 330 340 350
GFSLVALNLA GDSLDELIVS APMYRDRNIG AETGRIYIYR NIGATLSLVT
360 370 380 390 400
RIVGVAAYSR FGHAMASLGD ITGDGFDDVA VSAPFGAEQG TVYIYHSSAS
410 420 430 440 450
QFLTPTPQQV ITPSTLNLMP IIISEFESFG TALASFDVDG NGFNDLAIGS
460 470 480 490 500
YKDQSAVVLR TRPLAQVTTT LVATPGIVDI TDANQMMAYD VGTFSYFDVI
510 520 530 540 550
YSVEFNGQGS ITLDITLVSE RARRNQGLQQ RLFFRDTSDT AQREPMVTRQ
560 570 580 590 600
DVQLNQGQEQ TFTDRVFVQN GILDIFSGFT FDLEITARDF VRPENNGNER
610 620 630 640 650
LTNLDAFPVV SISGPSSLQV EIQNNCTGEC IADLAVTRNG DVTYTGARDP
660 670 680 690 700
NLLTVGEVTE VIIPISIQNK GNNAFRAQLV FNLPIQSLLF TSVSGEFITC
710 720 730 740 750
NQGNGNGQIV PFICDIGNPF EMDVTQSTEF RFRPADSLTG ERQHYLNFNV
760 770 780 790 800
TSSNEGNLTN DNTVGVTLQV NTVADIFVDE GIAFPDQVNH ASEPPTGDIV
810 820 830 840 850
NVTSLGPSFV TTFTIGNNGP SVIPNARLTI HWPLNVKDSE NKNYFLYLTG
860 870 880 890 900
WRTIQSTSVS VSCDTTYFNP AGLDIATSVD TAGTPGGIPG TSEGRRRRRS
910 920 930 940 950
VGGGMQPRRR RGRNTRIPRQ DMENLPVSVD RRVSCLPEDR DNIANNHTCA
960 970 980 990 1000
AIVCEVRQLR AGNRVQVEIS AVIDERHIAG IDSYTFFPSA QVEMVGSDHI
1010 1020 1030 1040 1050
NESNTKDNNA SAEFRSIPGE LVVPSGSSGD DESVPWYVIA VPIIAAVILI
1060 1070 1080
IVVAVVLYFC GFFRRKNKQE IEDQARENLA EENTAM
Length:1,086
Mass (Da):118,629
Last modified:January 1, 1998 - v1
Checksum:i269189D0364DBFA5
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X97283 mRNA Translation: CAA65943.1
PIRiT18523

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X97283 mRNA Translation: CAA65943.1
PIRiT18523

3D structure databases

ProteinModelPortaliO18428
ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Family and domain databases

Gene3Di2.130.10.130, 1 hit
InterProiView protein in InterPro
IPR013517 FG-GAP
IPR013519 Int_alpha_beta-p
IPR000413 Integrin_alpha
IPR013649 Integrin_alpha-2
IPR028994 Integrin_alpha_N
IPR032695 Integrin_dom_sf
PfamiView protein in Pfam
PF01839 FG-GAP, 1 hit
PF08441 Integrin_alpha2, 1 hit
PRINTSiPR01185 INTEGRINA
SMARTiView protein in SMART
SM00191 Int_alpha, 4 hits
SUPFAMiSSF69179 SSF69179, 3 hits
PROSITEiView protein in PROSITE
PS51470 FG_GAP, 6 hits
ProtoNetiSearch...

Entry informationi

Entry nameiO18428_GEOCY
AccessioniPrimary (citable) accession number: O18428
Entry historyiIntegrated into UniProtKB/TrEMBL: January 1, 1998
Last sequence update: January 1, 1998
Last modified: February 28, 2018
This is version 79 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.

Do not show this banner again