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Protein
Submitted name:

LD44762p

Gene

Rab8

Organism
Drosophila melanogaster (Fruit fly)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Enzyme and pathway databases

ReactomeiR-DME-5620916 VxPx cargo-targeting to cilium
R-DME-8873719 RAB geranylgeranylation

Names & Taxonomyi

Protein namesi
Submitted name:
LD44762pImported
Submitted name:
Rab8Imported
Submitted name:
Rab8, isoform AImported
Submitted name:
Rab8, isoform CImported
Gene namesi
Name:Rab8Imported
Synonyms:AAF49101Imported, Dm Rab8Imported, dm-Rab8Imported, Dmel\CG8287Imported, DmRab8Imported, DRAB8Imported, DRab8Imported, l(3)76BDuImported, O18338Imported, Rab-r8Imported, rab8Imported
ORF Names:CG8287Imported, Dmel_CG8287Imported
OrganismiDrosophila melanogaster (Fruit fly)Imported
Taxonomic identifieri7227 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaArthropodaHexapodaInsectaPterygotaNeopteraHolometabolaDipteraBrachyceraMuscomorphaEphydroideaDrosophilidaeDrosophilaSophophora
Proteomesi
  • UP000000803 Componenti: Chromosome 3L

Organism-specific databases

FlyBaseiFBgn0262518 Rab8

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Expressioni

Gene expression databases

BgeeiFBgn0262518 Expressed in 43 organ(s), highest expression level in embryo

Interactioni

Protein-protein interaction databases

STRINGi7227.FBpp0074690

Family & Domainsi

Phylogenomic databases

eggNOGiKOG0078 Eukaryota
ENOG410XPUI LUCA
GeneTreeiENSGT00890000139330
OMAiNRKMNDG
OrthoDBiEOG091G0LA6

Family and domain databases

InterProiView protein in InterPro
IPR027417 P-loop_NTPase
IPR005225 Small_GTP-bd_dom
IPR001806 Small_GTPase
PfamiView protein in Pfam
PF00071 Ras, 1 hit
SUPFAMiSSF52540 SSF52540, 1 hit
TIGRFAMsiTIGR00231 small_GTP, 1 hit

Sequence (1+)i

Sequence statusi: Complete.

This entry has 1 described isoform and 1 potential isoform that is computationally mapped.iShow all

O18338-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MAKTYDYLFK LLLIGDSGVG KTCILFRFSE DAFNTTFIST IGIDFKIRTI
60 70 80 90 100
ELDNKKIKLQ IWDTAGQERF RTITTAYYRG AMGIMLVYDI TQEKSFENIK
110 120 130 140 150
NWIRNIEENA SADVEKMLLG NKCELTDKRQ VSKERGEQLA IEYGIKFMET
160 170 180 190 200
SAKASINVEE AFLTLASDIK AKTEKRMEAN NPPKGGHQLK PMDSRTKDSW

LSRCSLL
Length:207
Mass (Da):23,691
Last modified:January 1, 1998 - v1
Checksum:iBE9DE812C77DCF09
GO

Computationally mapped potential isoform sequencesi

There is 1 potential isoform mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
M9NEE8M9NEE8_DROME
Rab8, isoform B
Rab8 AAF49101, CG8287, Dm Rab8, dm-Rab8, Dmel\CG8287 Rab8 AAF49101, CG8287, Dm Rab8, dm-Rab8, Dmel\CG8287, DmRab8, DRAB8, DRab8, l(3)76BDu, O18338, Rab-r8, rab8, CG8287, Dmel_CG8287
172Annotation score:

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE014296 Genomic DNA Translation: AAF49101.1
AY069671 mRNA Translation: AAL39816.1
AE014296 Genomic DNA Translation: AFH04508.1
D84347 mRNA Translation: BAA21711.1
AB112933 mRNA Translation: BAD07038.1
RefSeqiNP_001246837.1, NM_001259908.2
NP_524172.1, NM_079448.4
UniGeneiDm.2015

Genome annotation databases

EnsemblMetazoaiFBtr0074921; FBpp0074690; FBgn0262518
FBtr0308833; FBpp0300990; FBgn0262518
GeneIDi40168
UCSCiCG8287-RA d. melanogaster

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE014296 Genomic DNA Translation: AAF49101.1
AY069671 mRNA Translation: AAL39816.1
AE014296 Genomic DNA Translation: AFH04508.1
D84347 mRNA Translation: BAA21711.1
AB112933 mRNA Translation: BAD07038.1
RefSeqiNP_001246837.1, NM_001259908.2
NP_524172.1, NM_079448.4
UniGeneiDm.2015

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi7227.FBpp0074690

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblMetazoaiFBtr0074921; FBpp0074690; FBgn0262518
FBtr0308833; FBpp0300990; FBgn0262518
GeneIDi40168
UCSCiCG8287-RA d. melanogaster

Organism-specific databases

CTDi40168
FlyBaseiFBgn0262518 Rab8

Phylogenomic databases

eggNOGiKOG0078 Eukaryota
ENOG410XPUI LUCA
GeneTreeiENSGT00890000139330
OMAiNRKMNDG
OrthoDBiEOG091G0LA6

Enzyme and pathway databases

ReactomeiR-DME-5620916 VxPx cargo-targeting to cilium
R-DME-8873719 RAB geranylgeranylation

Miscellaneous databases

GenomeRNAii40168

Gene expression databases

BgeeiFBgn0262518 Expressed in 43 organ(s), highest expression level in embryo

Family and domain databases

InterProiView protein in InterPro
IPR027417 P-loop_NTPase
IPR005225 Small_GTP-bd_dom
IPR001806 Small_GTPase
PfamiView protein in Pfam
PF00071 Ras, 1 hit
SUPFAMiSSF52540 SSF52540, 1 hit
TIGRFAMsiTIGR00231 small_GTP, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiO18338_DROME
AccessioniPrimary (citable) accession number: O18338
Entry historyiIntegrated into UniProtKB/TrEMBL: January 1, 1998
Last sequence update: January 1, 1998
Last modified: September 12, 2018
This is version 165 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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