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Entry version 163 (29 Sep 2021)
Sequence version 2 (01 Mar 2003)
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Protein
Submitted name:

Tr-type G domain-containing protein

Gene

CELE_K10C3.5

Organism
Caenorhabditis elegans
Status
Unreviewed-Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Submitted name:
Tr-type G domain-containing proteinImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
ORF Names:CELE_K10C3.5Imported, K10C3.5Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiCaenorhabditis elegansImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri6239 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaEcdysozoaNematodaChromadoreaRhabditidaRhabditinaRhabditomorphaRhabditoideaRhabditidaePeloderinaeCaenorhabditis
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000001940 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome I

Organism-specific databases

WormBase

More...
WormBasei
K10C3.5a ; CE32469 ; WBGene00010732

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Proteomic databases

Encyclopedia of Proteome Dynamics

More...
EPDi
O17944

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
O17944

PeptideAtlas

More...
PeptideAtlasi
O17944

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
WBGene00010732, Expressed in pharyngeal muscle cell (C elegans) and 5 other tissues

ExpressionAtlas, Differential and Baseline Expression

More...
ExpressionAtlasi
O17944, baseline and differential

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

Protein interaction database and analysis system

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IntActi
O17944, 1 interactor

STRING: functional protein association networks

More...
STRINGi
6239.K10C3.5a

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
O17944

Database of comparative protein structure models

More...
ModBasei
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family_and_domains_section">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini18 – 241Tr-type GInterPro annotationAdd BLAST224

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG0467, Eukaryota

Ensembl GeneTree

More...
GeneTreei
ENSGT00550000074806

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
O17944

Identification of Orthologs from Complete Genome Data

More...
OMAi
SNIRNVC

Database of Orthologous Groups

More...
OrthoDBi
140796at2759

Database for complete collections of gene phylogenies

More...
PhylomeDBi
O17944

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
3.30.230.10, 1 hit
3.40.50.300, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR035647, EFG_III/V
IPR000640, EFG_V-like
IPR027417, P-loop_NTPase
IPR020568, Ribosomal_S5_D2-typ_fold
IPR014721, Ribosomal_S5_D2-typ_fold_subgr
IPR005225, Small_GTP-bd_dom
IPR000795, T_Tr_GTP-bd_dom
IPR009000, Transl_B-barrel_sf

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF00679, EFG_C, 1 hit
PF00009, GTP_EFTU, 1 hit

Protein Motif fingerprint database; a protein domain database

More...
PRINTSi
PR00315, ELONGATNFCT

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00838, EFG_C, 1 hit

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF50447, SSF50447, 1 hit
SSF52540, SSF52540, 1 hit
SSF54211, SSF54211, 1 hit
SSF54980, SSF54980, 2 hits

TIGRFAMs; a protein family database

More...
TIGRFAMsi
TIGR00231, small_GTP, 1 hit

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS51722, G_TR_2, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequence (1+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry has 1 described isoform and 1 potential isoform that is computationally mapped.Show allAlign All

O17944-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MESLETALKQ AAATKPAEHI RNVCLVAHVD HGKTSFADSL VSANAVISSR
60 70 80 90 100
MAGKLRYMDS REDEQTRGIT MKSSGISLLC EPLLINLIDS PGHVDFSGEV
110 120 130 140 150
TSALILSDIA LLLIDVIEGI CSQTEALIRQ VIRNGQAMIL VINKIDRLRV
160 170 180 190 200
ELKMSSSEAY QHMSRLIEGV NSCISQVLGG IVLEDDTWGN IEESEAKLHF
210 220 230 240 250
DPAKGNVIFS SALHSYAFGC EDFAQIAAEK MKVEKSALLP AMFGDFWIDS
260 270 280 290 300
TGSIRDGAAV KNKATLFERI VLEPLWRIHD LGLVENDATK LAEAAKKLGI
310 320 330 340 350
NLKSRRANEA FDELMRTWLP LPKASFRAVA RAPNVRSTFD TQHRLDHLTG
360 370 380 390 400
HRLDHPLRKF VLECNPEAMT LVFVVKLLQT EDKNLTSRRA ICRVLSGTLR
410 420 430 440 450
KGDTLYVLQQ QNNSSEVTST KIDRISILRG RDSIPTDTVT SGMICTIDAE
460 470 480 490 500
ILLQNTTLCE KPDFPCLKIG SQTGEALVRV SISTQQLDDM DDLREKLKLL
510 520 530 540 550
ALLDTSLKVM ELENGELAMV TAGEVHLQKC IKDLNDLGLV DLDVSEPIVP
560 570 580 590 600
FMETVIEDSV LSAPQIIEQE TECRIREALY IKLRVVPLGD AVVELLDKNS
610 620 630 640 650
SLISSIRRGE ADQTEIDEFQ KRFTSVCLET LPTLKGSWWF RKPKEVIESM
660 670 680 690 700
IDQIWAFGPE RARANILFNN VQNYDRDSVW RKTEFGVRRY DQALVAGFEL
710 720 730 740 750
FCNTGPLCNE IMHGIAVIVE EWNVDEEDGA IGGQMMTAIK ASCSAAAKKL
760 770 780 790 800
ALRLVAAMYR CTVTTASQAL GKVHAVLSQR KSKVLSEDIN EATNLFEVVS
810 820 830 840 850
LMPVVESFSF CDQLRKFTSG MASAQLQFSH WQVIDEDPYW TPSTLEEIEE
860 870 880 890
FGLKGDSPNH ARGYMDAVRR RKGLPTEDLI VESAEKQRNL KKNK
Length:894
Mass (Da):99,647
Last modified:March 1, 2003 - v2
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i34F6783A7D94DFC1
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There is 1 potential isoform mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
Q564S2Q564S2_CAEEL
Tr-type G domain-containing protein
CELE_K10C3.5, K10C3.5
705Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
BX284601 Genomic DNA Translation: CAB05774.2

Protein sequence database of the Protein Information Resource

More...
PIRi
T23556

NCBI Reference Sequences

More...
RefSeqi
NP_001021564.1, NM_001026393.2

Genome annotation databases

Ensembl metazoan genome annotation project

More...
EnsemblMetazoai
K10C3.5a.1; K10C3.5a.1; WBGene00010732

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
172838

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
cel:CELE_K10C3.5

UCSC genome browser

More...
UCSCi
K10C3.5b, c. elegans

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BX284601 Genomic DNA Translation: CAB05774.2
PIRiT23556
RefSeqiNP_001021564.1, NM_001026393.2

3D structure databases

SMRiO17944
ModBaseiSearch...

Protein-protein interaction databases

IntActiO17944, 1 interactor
STRINGi6239.K10C3.5a

Proteomic databases

EPDiO17944
PaxDbiO17944
PeptideAtlasiO17944

Genome annotation databases

EnsemblMetazoaiK10C3.5a.1; K10C3.5a.1; WBGene00010732
GeneIDi172838
KEGGicel:CELE_K10C3.5
UCSCiK10C3.5b, c. elegans

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
172838
WormBaseiK10C3.5a ; CE32469 ; WBGene00010732

Phylogenomic databases

eggNOGiKOG0467, Eukaryota
GeneTreeiENSGT00550000074806
InParanoidiO17944
OMAiSNIRNVC
OrthoDBi140796at2759
PhylomeDBiO17944

Gene expression databases

BgeeiWBGene00010732, Expressed in pharyngeal muscle cell (C elegans) and 5 other tissues
ExpressionAtlasiO17944, baseline and differential

Family and domain databases

Gene3Di3.30.230.10, 1 hit
3.40.50.300, 1 hit
InterProiView protein in InterPro
IPR035647, EFG_III/V
IPR000640, EFG_V-like
IPR027417, P-loop_NTPase
IPR020568, Ribosomal_S5_D2-typ_fold
IPR014721, Ribosomal_S5_D2-typ_fold_subgr
IPR005225, Small_GTP-bd_dom
IPR000795, T_Tr_GTP-bd_dom
IPR009000, Transl_B-barrel_sf
PfamiView protein in Pfam
PF00679, EFG_C, 1 hit
PF00009, GTP_EFTU, 1 hit
PRINTSiPR00315, ELONGATNFCT
SMARTiView protein in SMART
SM00838, EFG_C, 1 hit
SUPFAMiSSF50447, SSF50447, 1 hit
SSF52540, SSF52540, 1 hit
SSF54211, SSF54211, 1 hit
SSF54980, SSF54980, 2 hits
TIGRFAMsiTIGR00231, small_GTP, 1 hit
PROSITEiView protein in PROSITE
PS51722, G_TR_2, 1 hit

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiO17944_CAEEL
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: O17944
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: January 1, 1998
Last sequence update: March 1, 2003
Last modified: September 29, 2021
This is version 163 of the entry and version 2 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Technical termi

Proteomics identificationCombined sources, Reference proteomeImported
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