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Entry version 141 (07 Oct 2020)
Sequence version 1 (01 Jan 1998)
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Protein

Ataxin-3 homolog

Gene

atx-3

Organism
Caenorhabditis elegans
Status
Reviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Acts as chain editing deubiquitinating enzyme that binds and cleaves 'Lys-48'-linked polyubiquitin chains, with a preference for chains containing four or more ubiquitin molecules thereby modulating protein degradation by the ubiquitin-proteasome pathway (PubMed:19545544, PubMed:17234717, PubMed:21317884). Probably by regulating the IGF-1-insulin-like pathway, regulates lifespan (PubMed:21317884). Regulates germline DNA double-strand-break repair and apoptosis in response to DNA damage by recruiting E4 ubiquitin-protein ligase ufd-2 to DNA repair foci (PubMed:27669035). Interacts with key regulators of transcription and represses transcription (By similarity). Acts as a histone-binding protein that regulates transcription (By similarity).By similarity4 Publications

<p>This subsection of the <a href="http://www.uniprot.org/help/function%5Fsection">Function</a> section describes the catalytic activity of an enzyme, i.e. a chemical reaction that the enzyme catalyzes.<p><a href='/help/catalytic_activity' target='_top'>More...</a></p>Catalytic activityi

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/function%5Fsection">Function</a> section is used for enzymes and indicates the residues directly involved in catalysis.<p><a href='/help/act_site' target='_top'>More...</a></p>Active sitei20NucleophilePROSITE-ProRule annotation1
Active sitei117Proton acceptorPROSITE-ProRule annotation1
Active sitei132PROSITE-ProRule annotation1

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionHydrolase, Protease, Thiol protease
Biological processTranscription, Transcription regulation, Ubl conjugation pathway

Enzyme and pathway databases

Reactome - a knowledgebase of biological pathways and processes

More...
Reactomei
R-CEL-5689877, Josephin domain DUBs
R-CEL-9615017, FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes

Protein family/group databases

MEROPS protease database

More...
MEROPSi
C86.003

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Ataxin-3 homolog (EC:3.4.19.122 Publications)
Alternative name(s):
Machado-Joseph disease-like protein
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:atx-3
ORF Names:F28F8.6
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiCaenorhabditis elegansImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri6239 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaEcdysozoaNematodaChromadoreaRhabditidaRhabditinaRhabditomorphaRhabditoideaRhabditidaePeloderinaeCaenorhabditis
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000001940 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome V

Organism-specific databases

WormBase

More...
WormBasei
F28F8.6 ; CE09760 ; WBGene00006446 ; atx-3

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

Keywords - Cellular componenti

Cytoplasm, Nucleus

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

<p>This subsection of the 'Pathology and Biotech' section describes the in vivo effects caused by ablation of the gene (or one or more transcripts) coding for the protein described in the entry. This includes gene knockout and knockdown, provided experiments have been performed in the context of a whole organism or a specific tissue, and not at the single-cell level.<p><a href='/help/disruption_phenotype' target='_top'>More...</a></p>Disruption phenotypei

No visible phenotype (PubMed:17234717). In response to ionizing radiation-mediated DNA damage, the number of germline apoptotic corpses is increased, ufd-2 recruitment to nucleoli foci is impaired, the number of ubiquitin foci is increased and rad-51 retention to DNA damage foci is reduced; the increased germline apoptosis is suppressed in a ufd-2 (tm1380) mutant background (PubMed:27669035). At the higher temperature of 25 degrees Celsius, 60 percent of animals are uncoordinated (PubMed:19545544). Shows resistance to heat stress characterized by an increase in survival and expression of heat shock proteins such as hsp-16.2 and hsp-4 (PubMed:21526185). Expression of genes involved in the ubiquitin-proteasome pathway, motility, cell structure and signal transduction is affected (PubMed:17234717). In a cdc-48.1 (tm544) mutant background, causes a 50 percent increase in longevity, a delay in age-related muscle degeneration and resistance to oxidative and heat stresses (PubMed:21317884). In addition, induces dauer formation in 10 percent of animals and increases gene transcription of several genes including sod-3 and hsp-16.2 (PubMed:21317884). The overall levels of polyubiquitinated proteins is not affected (PubMed:21317884). RNAi-mediated knockdown of daf-16 abolishes the increase in lifespan (PubMed:21317884).5 Publications

Mutagenesis

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/manual/pathology%5Fand%5Fbiotech%5Fsection">'Pathology and Biotech'</a> section describes the effect of the experimental mutation of one or more amino acid(s) on the biological properties of the protein.<p><a href='/help/mutagen' target='_top'>More...</a></p>Mutagenesisi20C → A: Loss of catalytic activity. In a cdc-48.1 (tm544) mutant background, causes an increase in longevitiy and resistance to oxidative stress. 2 Publications1
Mutagenesisi232S → A: Loss of catalytic activity. 1 Publication1
Mutagenesisi260S → A: Loss of catalytic activity. 1 Publication1
Mutagenesisi296 – 299RRDR → HNHH: Loss of interaction with cdc-48.1 and cdc-48.2. 1 Publication4

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00000538351 – 317Ataxin-3 homologAdd BLAST317

Proteomic databases

Encyclopedia of Proteome Dynamics

More...
EPDi
O17850

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
O17850

PeptideAtlas

More...
PeptideAtlasi
O17850

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
O17850

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

<p>This subsection of the 'Expression' section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms. By default, the information is derived from experiments at the mRNA level, unless specified 'at protein level'.<br></br>Examples: <a href="http://www.uniprot.org/uniprot/P92958#expression">P92958</a>, <a href="http://www.uniprot.org/uniprot/Q8TDN4#expression">Q8TDN4</a>, <a href="http://www.uniprot.org/uniprot/O14734#expression">O14734</a><p><a href='/help/tissue_specificity' target='_top'>More...</a></p>Tissue specificityi

Expressed in germline (at protein level) (PubMed:27669035). Expressed in spermatheca, pharynx, dorsal and ventral cords, some head neurons, hypodermis, body wall muscles and coelomocytes (PubMed:17234717).2 Publications

<p>This subsection of the 'Expression' section provides information on the expression of the gene product at various stages of a cell, tissue or organism development. By default, the information is derived from experiments at the mRNA level, unless specified 'at the protein level'.<p><a href='/help/developmental_stage' target='_top'>More...</a></p>Developmental stagei

Expression begins during late embryogenesis and continues in larvae and adults.1 Publication

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
WBGene00006446, Expressed in adult organism and 5 other tissues

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the <a href="http://www.uniprot.org/help/interaction%5Fsection">'Interaction'</a> section provides information about the protein quaternary structure and interaction(s) with other proteins or protein complexes (with the exception of physiological receptor-ligand interactions which are annotated in the <a href="http://www.uniprot.org/help/function%5Fsection">'Function'</a> section).<p><a href='/help/subunit_structure' target='_top'>More...</a></p>Subunit structurei

Forms a complex composed of deubiquitinating enzyme atx-3, adapter ubxn-5 and cdc-48.1 (PubMed:19545544).

Forms a complex composed of deubiquitinating enzyme atx-3, E4 ubiquitin-protein ligase ufd-2 and cdc-48.1 (PubMed:21317884).

Interacts (via RRDR motif) with cdc-48.1 (via N-terminus) and cdc-48.2 (via N-terminus); the interaction with cdc-48.1 is not required for atx-3 enzymatic activity (PubMed:19545544, PubMed:21317884).

Interacts (via C-terminus) with ubxn-5 (PubMed:19545544). May interact with ned-8 (PubMed:17935801).

3 Publications

<p>This subsection of the '<a href="http://www.uniprot.org/help/interaction%5Fsection">Interaction</a>' section provides information about binary protein-protein interactions. The data presented in this section are a quality-filtered subset of binary interactions automatically derived from the <a href="https://www.ebi.ac.uk/intact/">IntAct database</a>. It is updated at every <a href="http://www.uniprot.org/help/synchronization">UniProt release</a>.<p><a href='/help/binary_interactions' target='_top'>More...</a></p>Binary interactionsi

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGRID)

More...
BioGRIDi
45043, 5 interactors

Database of interacting proteins

More...
DIPi
DIP-27501N

Protein interaction database and analysis system

More...
IntActi
O17850, 3 interactors

STRING: functional protein association networks

More...
STRINGi
6239.F28F8.6.1

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family%5Fand%5Fdomains%5Fsection">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini7 – 178JosephinPROSITE-ProRule annotationAdd BLAST172
Domaini219 – 239UIM 1CuratedAdd BLAST21
Domaini247 – 264UIM 2CuratedAdd BLAST18

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni296 – 299Interaction with cdc-48.1 and cdc-48.21 Publication4

Keywords - Domaini

Repeat

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG2935, Eukaryota

Ensembl GeneTree

More...
GeneTreei
ENSGT00390000001830

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
CLU_031228_1_1_1

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
O17850

Identification of Orthologs from Complete Genome Data

More...
OMAi
HESEFTE

Database of Orthologous Groups

More...
OrthoDBi
1482722at2759

Database for complete collections of gene phylogenies

More...
PhylomeDBi
O17850

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR033865, Ataxin-3
IPR006155, Josephin
IPR003903, UIM_dom

The PANTHER Classification System

More...
PANTHERi
PTHR14159, PTHR14159, 1 hit

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF02099, Josephin, 1 hit
PF02809, UIM, 2 hits

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM01246, Josephin, 1 hit

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS50957, JOSEPHIN, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

O17850-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MSKDDPINSI FFEHQEAALC AQHALNMLLQ DALYKWQDLR DLAIQMDKME
60 70 80 90 100
QQILGNANPT PGRSENMNES GYFSIQVLEK ALETFSLKLT NIENPAMVDY
110 120 130 140 150
KNNPLTARAY ICNLREHWFV LRKFGNQWFE LNSVNRGPKL LSDTYVSMFL
160 170 180 190 200
HQVSSEGYSI FVVQGVLPRS DADDLISLCP VVPPKVTPKK EQKLEKVMTK
210 220 230 240 250
FFNTVGKRLG GGSGAPPDSQ EEKDLAIAFA MSMETKDGSE VSRSSAEIDE
260 270 280 290 300
ENLRKAIELS QAPGPSEPAE IPLLTRSRSS TPPGASEPFS NAEQQRRDRQ
310
KFLERFEKKK EERNDEK
Length:317
Mass (Da):35,864
Last modified:January 1, 1998 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i31798FD62667FB19
GO

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
Z81071 Genomic DNA Translation: CAB03016.1

Protein sequence database of the Protein Information Resource

More...
PIRi
T21511

NCBI Reference Sequences

More...
RefSeqi
NP_506873.1, NM_074472.7

Genome annotation databases

Ensembl metazoan genome annotation project

More...
EnsemblMetazoai
F28F8.6.1; F28F8.6.1; WBGene00006446
F28F8.6.2; F28F8.6.2; WBGene00006446
F28F8.6.3; F28F8.6.3; WBGene00006446

UCSC genome browser

More...
UCSCi
F28F8.6.1, c. elegans

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
Z81071 Genomic DNA Translation: CAB03016.1
PIRiT21511
RefSeqiNP_506873.1, NM_074472.7

3D structure databases

Database of comparative protein structure models

More...
ModBasei
Search...

SWISS-MODEL Interactive Workspace

More...
SWISS-MODEL-Workspacei
Submit a new modelling project...

Protein-protein interaction databases

BioGRIDi45043, 5 interactors
DIPiDIP-27501N
IntActiO17850, 3 interactors
STRINGi6239.F28F8.6.1

Protein family/group databases

MEROPSiC86.003

PTM databases

iPTMnetiO17850

Proteomic databases

EPDiO17850
PaxDbiO17850
PeptideAtlasiO17850

Genome annotation databases

EnsemblMetazoaiF28F8.6.1; F28F8.6.1; WBGene00006446
F28F8.6.2; F28F8.6.2; WBGene00006446
F28F8.6.3; F28F8.6.3; WBGene00006446
UCSCiF28F8.6.1, c. elegans

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
180049
WormBaseiF28F8.6 ; CE09760 ; WBGene00006446 ; atx-3

Phylogenomic databases

eggNOGiKOG2935, Eukaryota
GeneTreeiENSGT00390000001830
HOGENOMiCLU_031228_1_1_1
InParanoidiO17850
OMAiHESEFTE
OrthoDBi1482722at2759
PhylomeDBiO17850

Enzyme and pathway databases

ReactomeiR-CEL-5689877, Josephin domain DUBs
R-CEL-9615017, FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes

Miscellaneous databases

Protein Ontology

More...
PROi
PR:O17850

Gene expression databases

BgeeiWBGene00006446, Expressed in adult organism and 5 other tissues

Family and domain databases

InterProiView protein in InterPro
IPR033865, Ataxin-3
IPR006155, Josephin
IPR003903, UIM_dom
PANTHERiPTHR14159, PTHR14159, 1 hit
PfamiView protein in Pfam
PF02099, Josephin, 1 hit
PF02809, UIM, 2 hits
SMARTiView protein in SMART
SM01246, Josephin, 1 hit
PROSITEiView protein in PROSITE
PS50957, JOSEPHIN, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiATX3_CAEEL
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: O17850
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: March 28, 2003
Last sequence update: January 1, 1998
Last modified: October 7, 2020
This is version 141 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programCaenorhabditis annotation project

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteome

Documents

  1. Caenorhabditis elegans
    Caenorhabditis elegans: entries, gene names and cross-references to WormBase
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