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Protein

Alkylglycerol monooxygenase

Gene

agmo-1

Organism
Caenorhabditis elegans
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Glyceryl-ether monooxygenase that cleaves the O-alkyl bond of ether lipids.By similarity

Catalytic activityi

1-alkyl-sn-glycerol + tetrahydrobiopterin + O2 = 1-O-alkyl-sn-glycerol + dihydrobiopterin + H2O.By similarity

Cofactori

Fe cationBy similarity

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionOxidoreductase
LigandIron

Enzyme and pathway databases

ReactomeiR-CEL-75109 Triglyceride biosynthesis

Names & Taxonomyi

Protein namesi
Recommended name:
Alkylglycerol monooxygenaseImported (EC:1.14.16.5By similarity)
Alternative name(s):
Transmembrane protein 195 homolog
Gene namesi
Name:agmo-1Imported
ORF Names:BE10.2Imported
OrganismiCaenorhabditis elegans
Taxonomic identifieri6239 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaNematodaChromadoreaRhabditidaRhabditoideaRhabditidaePeloderinaeCaenorhabditis
Proteomesi
  • UP000001940 Componenti: Chromosome III

Organism-specific databases

WormBaseiBE10.2 ; CE30592 ; WBGene00007210 ; agmo-1

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei56 – 76HelicalSequence analysisAdd BLAST21
Transmembranei104 – 124HelicalSequence analysisAdd BLAST21
Transmembranei366 – 386HelicalSequence analysisAdd BLAST21
Transmembranei396 – 416HelicalSequence analysisAdd BLAST21
Transmembranei430 – 450HelicalSequence analysisAdd BLAST21
Transmembranei452 – 472HelicalSequence analysisAdd BLAST21

Keywords - Cellular componenti

Endoplasmic reticulum, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00002993051 – 505Alkylglycerol monooxygenaseAdd BLAST505

Proteomic databases

EPDiO17554
PaxDbiO17554

Expressioni

Gene expression databases

BgeeiWBGene00007210 Expressed in 4 organ(s), highest expression level in multi-cellular organism
ExpressionAtlasiO17554 baseline and differential

Interactioni

Protein-protein interaction databases

STRINGi6239.BE10.2

Structurei

3D structure databases

ProteinModelPortaliO17554
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Motif

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Motifi145 – 149Histidine box-15
Motifi158 – 162Histidine box-25
Motifi234 – 238Histidine box-35

Sequence similaritiesi

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiKOG0872 Eukaryota
COG3000 LUCA
GeneTreeiENSGT00440000033807
InParanoidiO17554
KOiK15537
OMAiHEAGFFW
OrthoDBiEOG091G0P9T
PhylomeDBiO17554

Family and domain databases

InterProiView protein in InterPro
IPR006694 Fatty_acid_hydroxylase
PfamiView protein in Pfam
PF04116 FA_hydroxylase, 1 hit

Sequencei

Sequence statusi: Complete.

O17554-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MNETAWLDRV FSNTSLGHRL LDRLTLTNLR HAFYLISPYE TTVESIDDVP
60 70 80 90 100
NYNAEVSAWW LVFLTAEFFI LFISGHEDRF ALNDSITSIC AGMLSQCFKF
110 120 130 140 150
GGRAVAIFLY VIVWDNWRIL ELPWDSPWTW IFCLFFQDFM YYLGHRAVHE
160 170 180 190 200
AGFFWGLHTI HHSSEYYNFS TALRQAAIQD AGLAIYDCIQ AFFIPPSIFL
210 220 230 240 250
VHRYFSEIFQ FIMHTSLVDT MGPLGLVFNT PSHHRVHHGR NPYCIDKNYG
260 270 280 290 300
GVFIIWDKMF NTFEAERHDD PPIYGLVTNE NTFNQIYLQF HALWDILIFK
310 320 330 340 350
GFTKDVKGEP MFPGVVNKLK ATVFPPGWFP GVPVTPFFHW MSMVNPAHGV
360 370 380 390 400
PEPEKPVLRY SPPARILVKV YVASSFLLLL AIFFHFEYDR NHLSYLDCTV
410 420 430 440 450
KIAYFVVTMQ CFGAFFDMKW YARYIEIARC CGVLIYYGVL MFDHIGAGTH
460 470 480 490 500
RLFVISLHIM AIALWTTDVL VEKLSQCCSK NQSINPEKGD LERAPEIASI

SKNVQ
Length:505
Mass (Da):58,491
Last modified:October 1, 2002 - v2
Checksum:i22C40C34FBA42820
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
Z93372 Genomic DNA Translation: CAB07547.2
PIRiT18789
RefSeqiNP_499664.2, NM_067263.5
UniGeneiCel.19986

Genome annotation databases

EnsemblMetazoaiBE10.2; BE10.2; WBGene00007210
GeneIDi176695
KEGGicel:CELE_BE10.2
UCSCiBE10.2 c. elegans

Similar proteinsi

Entry informationi

Entry nameiALKMO_CAEEL
AccessioniPrimary (citable) accession number: O17554
Entry historyiIntegrated into UniProtKB/Swiss-Prot: September 11, 2007
Last sequence update: October 1, 2002
Last modified: September 12, 2018
This is version 106 of the entry and version 2 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programCaenorhabditis annotation project

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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