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Protein
Submitted name:

ASpartyl Protease

Gene

asp-7

Organism
Caenorhabditis elegans
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

Caution

Lacks conserved residue(s) required for the propagation of feature annotation.PROSITE-ProRule annotation

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Active sitei80PROSITE-ProRule annotation1
Active sitei263PROSITE-ProRule annotation1

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionAspartyl proteasePROSITE-ProRule annotation, Hydrolase, Protease

Protein family/group databases

MEROPSiA01.A77

Names & Taxonomyi

Protein namesi
Submitted name:
ASpartyl ProteaseImported
Gene namesi
Name:asp-7Imported
ORF Names:CELE_F59D6.2Imported, F59D6.2Imported
OrganismiCaenorhabditis elegansImported
Taxonomic identifieri6239 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaNematodaChromadoreaRhabditidaRhabditoideaRhabditidaePeloderinaeCaenorhabditis
Proteomesi
  • UP000001940 Componenti: Chromosome V

Organism-specific databases

WormBaseiF59D6.2 ; CE35328 ; WBGene00019104 ; asp-7

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 17Sequence analysisAdd BLAST17
ChainiPRO_500415701918 – 380Sequence analysisAdd BLAST363

Proteomic databases

PaxDbiO16339
PeptideAtlasiO16339

Expressioni

Gene expression databases

BgeeiWBGene00019104 Expressed in 2 organ(s), highest expression level in multi-cellular organism

Interactioni

Protein-protein interaction databases

STRINGi6239.F59D6.2

Structurei

3D structure databases

ProteinModelPortaliO16339
SMRiO16339
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini62 – 374Peptidase A1InterPro annotationAdd BLAST313

Sequence similaritiesi

Belongs to the peptidase A1 family.PROSITE-ProRule annotationSAAS annotation

Keywords - Domaini

SignalSequence analysis

Phylogenomic databases

eggNOGiKOG1339 Eukaryota
ENOG410XNV7 LUCA
GeneTreeiENSGT00920000150389
HOGENOMiHOG000197681
InParanoidiO16339
OMAiENCAANG
OrthoDBiEOG091G09OP
PhylomeDBiO16339

Family and domain databases

CDDicd05471 pepsin_like, 1 hit
Gene3Di2.40.70.10, 2 hits
InterProiView protein in InterPro
IPR001461 Aspartic_peptidase_A1
IPR034164 Pepsin-like_dom
IPR033121 PEPTIDASE_A1
IPR021109 Peptidase_aspartic_dom_sf
PANTHERiPTHR13683 PTHR13683, 1 hit
PfamiView protein in Pfam
PF00026 Asp, 1 hit
PRINTSiPR00792 PEPSIN
SUPFAMiSSF50630 SSF50630, 1 hit
PROSITEiView protein in PROSITE
PS51767 PEPTIDASE_A1, 1 hit

Sequencei

Sequence statusi: Complete.

O16339-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MTEKLTILLA LLVFCSAGQF SISLEKSVPL REQLIREGRE LARLQQLSTG
60 70 80 90 100
NESIYDHFDE YYTVSVRIGT PAQHFEVALD TTSSNLWVFG VECKSQSCQG
110 120 130 140 150
HRIREYNRTA SSTFIAGTSN FVLPFNDGDV SGDLGKDNIQ FAGSKIQNQD
160 170 180 190 200
FGIGTDATRL SGVTFDGVLG LGWPATALNG TSTTMQNLLP QLDQPLFTTY
210 220 230 240 250
FTKSSVHNGT VGGEITFGAI DTTHCQSQIN YVRLAYDSLW SYSIDGFSFG
260 270 280 290 300
NYSRNQTDTA IPDTTSSYTG VPNLVLAEIV IATGAQYDWN HQAYTLPCSS
310 320 330 340 350
TATLPDLVFT IGGNSYNVRA VEYVVNLNLP NGQCALSLFG TFSSPSGPLW
360 370 380
VFGDNFLRSY CHIFDFGNSR IGLAKAIQNY
Length:380
Mass (Da):41,581
Last modified:March 1, 2004 - v2
Checksum:i18B833E433C52288
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BX284605 Genomic DNA Translation: CCD67829.1
PIRiT31771
RefSeqiNP_503826.2, NM_071425.2
UniGeneiCel.3289

Genome annotation databases

EnsemblMetazoaiF59D6.2; F59D6.2; WBGene00019104
GeneIDi186613
KEGGicel:CELE_F59D6.2
UCSCiF59D6.2 c. elegans

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BX284605 Genomic DNA Translation: CCD67829.1
PIRiT31771
RefSeqiNP_503826.2, NM_071425.2
UniGeneiCel.3289

3D structure databases

ProteinModelPortaliO16339
SMRiO16339
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi6239.F59D6.2

Protein family/group databases

MEROPSiA01.A77

Proteomic databases

PaxDbiO16339
PeptideAtlasiO16339

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblMetazoaiF59D6.2; F59D6.2; WBGene00019104
GeneIDi186613
KEGGicel:CELE_F59D6.2
UCSCiF59D6.2 c. elegans

Organism-specific databases

CTDi186613
WormBaseiF59D6.2 ; CE35328 ; WBGene00019104 ; asp-7

Phylogenomic databases

eggNOGiKOG1339 Eukaryota
ENOG410XNV7 LUCA
GeneTreeiENSGT00920000150389
HOGENOMiHOG000197681
InParanoidiO16339
OMAiENCAANG
OrthoDBiEOG091G09OP
PhylomeDBiO16339

Gene expression databases

BgeeiWBGene00019104 Expressed in 2 organ(s), highest expression level in multi-cellular organism

Family and domain databases

CDDicd05471 pepsin_like, 1 hit
Gene3Di2.40.70.10, 2 hits
InterProiView protein in InterPro
IPR001461 Aspartic_peptidase_A1
IPR034164 Pepsin-like_dom
IPR033121 PEPTIDASE_A1
IPR021109 Peptidase_aspartic_dom_sf
PANTHERiPTHR13683 PTHR13683, 1 hit
PfamiView protein in Pfam
PF00026 Asp, 1 hit
PRINTSiPR00792 PEPSIN
SUPFAMiSSF50630 SSF50630, 1 hit
PROSITEiView protein in PROSITE
PS51767 PEPTIDASE_A1, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiO16339_CAEEL
AccessioniPrimary (citable) accession number: O16339
Entry historyiIntegrated into UniProtKB/TrEMBL: January 1, 1998
Last sequence update: March 1, 2004
Last modified: September 12, 2018
This is version 123 of the entry and version 2 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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