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Entry version 152 (17 Jun 2020)
Sequence version 1 (01 Jan 1998)
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Protein

Homeobox protein goosecoid-2

Gene

GSC2

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

May have a role in development. May regulate its own transcription. May bind the bicoid consensus sequence TAATCC.

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/function%5Fsection">Function</a> section specifies the position and type of each DNA-binding domain present within the protein.<p><a href='/help/dna_bind' target='_top'>More...</a></p>DNA bindingi126 – 185HomeoboxPROSITE-ProRule annotationAdd BLAST60

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionDNA-binding

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Homeobox protein goosecoid-2
Short name:
GSC-2
Alternative name(s):
Homeobox protein goosecoid-like
Short name:
GSC-L
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:GSC2
Synonyms:GSCL
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 22

Organism-specific databases

Eukaryotic Pathogen Database Resources

More...
EuPathDBi
HostDB:ENSG00000063515.2

Human Gene Nomenclature Database

More...
HGNCi
HGNC:4613 GSC2

Online Mendelian Inheritance in Man (OMIM)

More...
MIMi
601845 gene

neXtProt; the human protein knowledge platform

More...
neXtProti
NX_O15499

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

Keywords - Cellular componenti

Nucleus

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

DisGeNET

More...
DisGeNETi
2928

Open Targets

More...
OpenTargetsi
ENSG00000063515

The Pharmacogenetics and Pharmacogenomics Knowledge Base

More...
PharmGKBi
PA162390265

Miscellaneous databases

Pharos NIH Druggable Genome Knowledgebase

More...
Pharosi
O15499 Tbio

Polymorphism and mutation databases

BioMuta curated single-nucleotide variation and disease association database

More...
BioMutai
GSC2

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00000488911 – 205Homeobox protein goosecoid-2Add BLAST205

Proteomic databases

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
O15499

PRoteomics IDEntifications database

More...
PRIDEi
O15499

ProteomicsDB: a multi-organism proteome resource

More...
ProteomicsDBi
48698

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
O15499

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...
PhosphoSitePlusi
O15499

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

<p>This subsection of the 'Expression' section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms. By default, the information is derived from experiments at the mRNA level, unless specified 'at protein level'.<br></br>Examples: <a href="http://www.uniprot.org/uniprot/P92958#expression">P92958</a>, <a href="http://www.uniprot.org/uniprot/Q8TDN4#expression">Q8TDN4</a>, <a href="http://www.uniprot.org/uniprot/O14734#expression">O14734</a><p><a href='/help/tissue_specificity' target='_top'>More...</a></p>Tissue specificityi

Detected in adult testis and pituitary, and in 9-10 week fetal tissue (thorax). Probably expressed in other tissues at low levels.

<p>This subsection of the 'Expression' section provides information on the expression of the gene product at various stages of a cell, tissue or organism development. By default, the information is derived from experiments at the mRNA level, unless specified 'at the protein level'.<p><a href='/help/developmental_stage' target='_top'>More...</a></p>Developmental stagei

Expressed in early human development as well as in a limited number of adult tissues.

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSG00000063515 Expressed in testis and 4 other tissues

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
O15499 HS

Organism-specific databases

Human Protein Atlas

More...
HPAi
ENSG00000063515 Tissue enriched (testis)

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the '<a href="http://www.uniprot.org/help/interaction%5Fsection%27">Interaction</a> section provides information about binary protein-protein interactions. The data presented in this section are a quality-filtered subset of binary interactions automatically derived from the <a href="https://www.ebi.ac.uk/intact/">IntAct database</a>. It is updated at every <a href="http://www.uniprot.org/help/synchronization">UniProt release</a>.<p><a href='/help/binary_interactions' target='_top'>More...</a></p>Binary interactionsi

O15499
With#Exp.IntAct
ALPP [P05187]3EBI-19954058,EBI-1211484
ANXA5 [P08758]3EBI-19954058,EBI-296601
ASPH - isoform 6 [Q12797-6]3EBI-19954058,EBI-12092171
BEST3 - isoform 5 [Q8N1M1-5]3EBI-19954058,EBI-20140863
BNIP2 [Q12982]3EBI-19954058,EBI-752094
C19orf47 - isoform 2 [Q8N9M1-2]3EBI-19954058,EBI-10979594
C1D [Q13901]3EBI-19954058,EBI-3844053
CALR [P27797]3EBI-19954058,EBI-1049597
CDKN2D [P55273]3EBI-19954058,EBI-745859
CIAO2A [Q9H5X1]3EBI-19954058,EBI-752069
COL8A1 [P27658]3EBI-19954058,EBI-747133
CRCP - isoform 2 [O75575-2]3EBI-19954058,EBI-12880830
CSNK2A1 [P68400]3EBI-19954058,EBI-347804
DYRK1B [Q9Y463]3EBI-19954058,EBI-634187
EGLN3 [Q9H6Z9]3EBI-19954058,EBI-1175354
EIF5A [P63241]3EBI-19954058,EBI-373150
ETFDH [Q16134]3EBI-19954058,EBI-2870454
FAM221B [A6H8Z2]3EBI-19954058,EBI-12006844
FKBP6 [O75344]3EBI-19954058,EBI-744771
GALNT11 - isoform 2 [Q8NCW6-2]3EBI-19954058,EBI-13364322
GCM2 [O75603]3EBI-19954058,EBI-10188645
GTF2H5 [Q6ZYL4]3EBI-19954058,EBI-6380438
GTSF1L [Q9H1H1]3EBI-19954058,EBI-19128683
GUCA1A [P43080]3EBI-19954058,EBI-6873005
GUCY1A2 [P33402]3EBI-19954058,EBI-6911715
HMBOX1 [Q6NT76]3EBI-19954058,EBI-2549423
ISX [Q2M1V0]3EBI-19954058,EBI-6426064
KDM6A [O15550]3EBI-19954058,EBI-4292203
KLHL38 [Q2WGJ6]3EBI-19954058,EBI-6426443
KRT34 [O76011]3EBI-19954058,EBI-1047093
KRTAP5-9 [P26371]3EBI-19954058,EBI-3958099
LCE3E [Q5T5B0]3EBI-19954058,EBI-10245456
LTO1 [Q8WV07]3EBI-19954058,EBI-12249832
MAD2L2 [Q9UI95]3EBI-19954058,EBI-77889
MAPK9 [P45984]3EBI-19954058,EBI-713568
MARF1 [Q9Y4F3]3EBI-19954058,EBI-5235902
MID2 - isoform 2 [Q9UJV3-2]3EBI-19954058,EBI-10172526
MORF4L1 - isoform 2 [Q9UBU8-2]3EBI-19954058,EBI-10288852
MRPL53 [Q96EL3]3EBI-19954058,EBI-2513715
MRPS23 [Q9Y3D9]3EBI-19954058,EBI-1054270
NME7 [Q9Y5B8]3EBI-19954058,EBI-744782
PACSIN2 [Q9UNF0]3EBI-19954058,EBI-742503
PDE4C - isoform PDE4C2 [Q08493-2]3EBI-19954058,EBI-12169289
PRKAB2 [O43741]3EBI-19954058,EBI-1053424
PTER [Q96BW5]3EBI-19954058,EBI-4291023
SCAF1 [Q9H7N4]3EBI-19954058,EBI-1222181
SDCBP [O00560]3EBI-19954058,EBI-727004
TIPIN [Q9BVW5]3EBI-19954058,EBI-2515360
TNPO2 - isoform 2 [O14787-2]3EBI-19954058,EBI-12076664
TSR2 [Q969E8]3EBI-19954058,EBI-746981
UBE2R2 [Q712K3]3EBI-19954058,EBI-2340879
VCX2 [Q3SXR9]3EBI-19954058,EBI-11983741
XRCC4 [Q13426]3EBI-19954058,EBI-717592
YPEL5 [P62699]3EBI-19954058,EBI-11721624
ZNF444 - isoform 2 [Q8N0Y2-2]3EBI-19954058,EBI-12010736
ZNF587 [Q96SQ5]3EBI-19954058,EBI-6427977

Protein-protein interaction databases

Protein interaction database and analysis system

More...
IntActi
O15499, 56 interactors

STRING: functional protein association networks

More...
STRINGi
9606.ENSP00000086933

Miscellaneous databases

RNAct, Protein-RNA interaction predictions for model organisms.

More...
RNActi
O15499 protein

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
O15499

Database of comparative protein structure models

More...
ModBasei
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes the position of regions of compositional bias within the protein and the particular amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi2 – 5Poly-Ala4
Compositional biasi64 – 70Poly-Cys7

<p>This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Keywords - Domaini

Homeobox

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG0490 Eukaryota
ENOG410YIJ3 LUCA

Ensembl GeneTree

More...
GeneTreei
ENSGT00940000162536

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
CLU_122191_0_0_1

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
O15499

KEGG Orthology (KO)

More...
KOi
K09325

Identification of Orthologs from Complete Genome Data

More...
OMAi
SPRAGPC

Database of Orthologous Groups

More...
OrthoDBi
1270742at2759

Database for complete collections of gene phylogenies

More...
PhylomeDBi
O15499

TreeFam database of animal gene trees

More...
TreeFami
TF351613

Family and domain databases

Conserved Domains Database

More...
CDDi
cd00086 homeodomain, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR009057 Homeobox-like_sf
IPR017970 Homeobox_CS
IPR001356 Homeobox_dom

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF00046 Homeodomain, 1 hit

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00389 HOX, 1 hit

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF46689 SSF46689, 1 hit

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS00027 HOMEOBOX_1, 1 hit
PS50071 HOMEOBOX_2, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

O15499-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MAAAAGGAAS RRGAGRPCPF SIEHILSSLP ERSLPARAAC PPQPAGRQSP
60 70 80 90 100
AKPEEPGAPE AAPCACCCCC GPRAAPCGPP EAAAGLGARL AWPLRLGPAV
110 120 130 140 150
PLSLGAPAGG SGALPGAVGP GSQRRTRRHR TIFSEEQLQA LEALFVQNQY
160 170 180 190 200
PDVSTRERLA GRIRLREERV EVWFKNRRAK WRHQKRASAS ARLLPGVKKS

PKGSC
Length:205
Mass (Da):21,545
Last modified:January 1, 1998 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i665C33D9C454E7A7
GO

Natural variant

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section describes natural variant(s) of the protein sequence.<p><a href='/help/variant' target='_top'>More...</a></p>Natural variantiVAR_00854947R → C1 PublicationCorresponds to variant dbSNP:rs34341950Ensembl.1

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
U96402 Genomic DNA Translation: AAC39544.1

The Consensus CDS (CCDS) project

More...
CCDSi
CCDS13757.1

NCBI Reference Sequences

More...
RefSeqi
NP_005306.1, NM_005315.1

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENST00000086933; ENSP00000086933; ENSG00000063515

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
2928

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
hsa:2928

UCSC genome browser

More...
UCSCi
uc011ags.3 human

Keywords - Coding sequence diversityi

Polymorphism

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U96402 Genomic DNA Translation: AAC39544.1
CCDSiCCDS13757.1
RefSeqiNP_005306.1, NM_005315.1

3D structure databases

SMRiO15499
ModBaseiSearch...

Protein-protein interaction databases

IntActiO15499, 56 interactors
STRINGi9606.ENSP00000086933

PTM databases

iPTMnetiO15499
PhosphoSitePlusiO15499

Polymorphism and mutation databases

BioMutaiGSC2

Proteomic databases

PaxDbiO15499
PRIDEiO15499
ProteomicsDBi48698

Protocols and materials databases

Antibodypedia a portal for validated antibodies

More...
Antibodypediai
7476 69 antibodies

The DNASU plasmid repository

More...
DNASUi
2928

Genome annotation databases

EnsembliENST00000086933; ENSP00000086933; ENSG00000063515
GeneIDi2928
KEGGihsa:2928
UCSCiuc011ags.3 human

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
2928
DisGeNETi2928
EuPathDBiHostDB:ENSG00000063515.2

GeneCards: human genes, protein and diseases

More...
GeneCardsi
GSC2
HGNCiHGNC:4613 GSC2
HPAiENSG00000063515 Tissue enriched (testis)
MIMi601845 gene
neXtProtiNX_O15499
OpenTargetsiENSG00000063515
PharmGKBiPA162390265

GenAtlas: human gene database

More...
GenAtlasi
Search...

Phylogenomic databases

eggNOGiKOG0490 Eukaryota
ENOG410YIJ3 LUCA
GeneTreeiENSGT00940000162536
HOGENOMiCLU_122191_0_0_1
InParanoidiO15499
KOiK09325
OMAiSPRAGPC
OrthoDBi1270742at2759
PhylomeDBiO15499
TreeFamiTF351613

Miscellaneous databases

BioGRID ORCS database of CRISPR phenotype screens

More...
BioGRID-ORCSi
2928 12 hits in 810 CRISPR screens

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

More...
GenomeRNAii
2928
PharosiO15499 Tbio

Protein Ontology

More...
PROi
PR:O15499
RNActiO15499 protein

The Stanford Online Universal Resource for Clones and ESTs

More...
SOURCEi
Search...

Gene expression databases

BgeeiENSG00000063515 Expressed in testis and 4 other tissues
GenevisibleiO15499 HS

Family and domain databases

CDDicd00086 homeodomain, 1 hit
InterProiView protein in InterPro
IPR009057 Homeobox-like_sf
IPR017970 Homeobox_CS
IPR001356 Homeobox_dom
PfamiView protein in Pfam
PF00046 Homeodomain, 1 hit
SMARTiView protein in SMART
SM00389 HOX, 1 hit
SUPFAMiSSF46689 SSF46689, 1 hit
PROSITEiView protein in PROSITE
PS00027 HOMEOBOX_1, 1 hit
PS50071 HOMEOBOX_2, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiGSC2_HUMAN
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: O15499
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: May 30, 2000
Last sequence update: January 1, 1998
Last modified: June 17, 2020
This is version 152 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
  2. Human entries with polymorphisms or disease mutations
    List of human entries with polymorphisms or disease mutations
  3. Human polymorphisms and disease mutations
    Index of human polymorphisms and disease mutations
  4. MIM cross-references
    Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
  5. Human chromosome 22
    Human chromosome 22: entries, gene names and cross-references to MIM
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