CCL25

Functionⁱ

Potentially involved in T-cell development. Recombinant protein shows chemotactic activity on thymocytes, macrophages, THP-1 cells, and dendritics cells but is inactive on peripheral blood lymphocytes and neutrophils. Binds to CCR9. Isoform 2 is an antagonist of isoform 1. Binds to atypical chemokine receptor ACKR4 and mediates the recruitment of beta-arrestin (ARRB1/2) to ACKR4.

GO - Molecular functionⁱ

CCR10 chemokine receptor binding
Source: BHF-UCL
Inferred from direct assayⁱ
- 10706668
CCR chemokine receptor binding
Source: GO_Central
Inferred from biological aspect of ancestorⁱ
- 21873635
chemokine activity
Source: UniProtKB
Inferred from direct assayⁱ
- 18308860
chemokine receptor binding
Source: UniProtKB
Inferred from direct assayⁱ
- 23341447
hormone activity
Source: ProtInc
Traceable author statementⁱ
- 9285413

View the complete GO annotation on QuickGO ...

GO - Biological processⁱ

antimicrobial humoral immune response mediated by antimicrobial peptide
Source: UniProtKB
Inferred from direct assayⁱ
- 12949249
cell chemotaxis
Source: UniProtKB
Inferred from direct assayⁱ
- 18308860
cell surface receptor signaling pathway
Source: ProtInc
Traceable author statementⁱ
- 10640743
cellular response to interferon-gamma
Source: GO_Central
Inferred from biological aspect of ancestorⁱ
- 21873635
cellular response to interleukin-1
Source: GO_Central
Inferred from biological aspect of ancestorⁱ
- 21873635
cellular response to tumor necrosis factor
Source: GO_Central
Inferred from biological aspect of ancestorⁱ
- 21873635
chemokine-mediated signaling pathway
Source: GO_Central
Inferred from biological aspect of ancestorⁱ
- 21873635
chemotaxis
Source: ProtInc
Traceable author statementⁱ
- 10640743
G protein-coupled receptor signaling pathway
Source: UniProtKB
Inferred from direct assayⁱ
- 18308860
immune response
Source: ProtInc
Traceable author statementⁱ
- 10640743
inflammatory response
Source: GO_Central
Inferred from biological aspect of ancestorⁱ
- 21873635
killing of cells of other organism
Source: UniProtKB
Inferred from direct assayⁱ
- 12949249
lymphocyte chemotaxis
Source: GO_Central
Inferred from biological aspect of ancestorⁱ
- 21873635
monocyte chemotaxis
Source: GO_Central
Inferred from biological aspect of ancestorⁱ
- 21873635
negative regulation of leukocyte tethering or rolling
Source: UniProtKB
Inferred from direct assayⁱ
- 18308860
neutrophil chemotaxis
Source: GO_Central
Inferred from biological aspect of ancestorⁱ
- 21873635
positive regulation of cell-matrix adhesion
Source: UniProtKB
Inferred from direct assayⁱ
- 18308860
positive regulation of ERK1 and ERK2 cascade
Source: GO_Central
Inferred from biological aspect of ancestorⁱ
- 21873635
positive regulation of GTPase activity
Source: GO_Central
Inferred from biological aspect of ancestorⁱ
- 21873635

View the complete GO annotation on QuickGO ...

Keywordsⁱ

Molecular function	Cytokine
Biological process	Chemotaxis, Inflammatory response

Enzyme and pathway databases

Reactomeⁱ	R-HSA-380108 Chemokine receptors bind chemokines R-HSA-418594 G alpha (i) signalling events
SIGNORⁱ	O15444

Names & Taxonomyⁱ

Protein namesⁱ	Recommended name: C-C motif chemokine 25 Alternative name(s): Chemokine TECK Small-inducible cytokine A25 Thymus-expressed chemokine
Gene namesⁱ	Name:CCL25 Synonyms:SCYA25, TECK
Organismⁱ	Homo sapiens (Human)
Taxonomic identifierⁱ	9606 [NCBI]
Taxonomic lineageⁱ	cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Dipnotetrapodomorpha › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Boreoeutheria › Euarchontoglires › Primates › Haplorrhini › Simiiformes › Catarrhini › Hominoidea › Hominidae › Homininae › Homo
Proteomesⁱ	UP000005640 Componentⁱ: Chromosome 19

Organism-specific databases

EuPathDBⁱ	HostDB:ENSG00000131142.13
Human Gene Nomenclature Database More...HGNCⁱ	HGNC:10624 CCL25
MIMⁱ	602565 gene
neXtProtⁱ	NX_O15444

Keywords - Cellular componentⁱ

Secreted

Pathology & Biotechⁱ

Organism-specific databases

DisGeNET More...DisGeNETⁱ	6370
Open Targets More...OpenTargetsⁱ	ENSG00000131142
PharmGKBⁱ	PA35556

Polymorphism and mutation databases

BioMutaⁱ	CCL25

BioMutaⁱ

CCL25

PTM / Processingⁱ

Molecule processing

Feature key	Position(s)	DescriptionActions	Graphical view	Length
Signal peptideⁱ	1 – 23	Sequence analysisAdd BLAST		23
ChainⁱPRO_0000005235	24 – 150	C-C motif chemokine 25Add BLAST		127

Amino acid modifications

Feature key	Position(s)	DescriptionActions	Graphical view	Length
Disulfide bondⁱ	30 ↔ 58	By similarity
Disulfide bondⁱ	31 ↔ 75	By similarity

Keywords - PTMⁱ

Disulfide bond

Proteomic databases

PaxDbⁱ	O15444
PRIDEⁱ	O15444
ProteomicsDBⁱ	48672 48673 [O15444-2] 48674 [O15444-3]

PTM databases

iPTMnetⁱ	O15444
PhosphoSitePlusⁱ	O15444

Expressionⁱ

Tissue specificityⁱ

Specifically expressed by thymic dendritic cells. High levels in thymus and small intestine.

Gene expression databases

Bgeeⁱ	ENSG00000131142 Expressed in 59 organ(s), highest expression level in intestine
CleanExⁱ	HS_CCL25
ExpressionAtlasⁱ	O15444 baseline and differential
Genevisibleⁱ	O15444 HS

Organism-specific databases

Human Protein Atlas More...HPAⁱ	HPA055883

HPAⁱ

HPA055883

Interactionⁱ

Binary interactionsⁱ

With	Entry	#Exp.	IntAct
CCL17	Q92583	2	EBI-7783341,EBI-16640146
CCL5	P13501	2	EBI-7783341,EBI-2848366
CXCL12	P48061	2	EBI-7783341,EBI-3913254
PF4	P02776	3	EBI-7783341,EBI-2565740
PF4V1	P10720	2	EBI-7783341,EBI-1223944

GO - Molecular functionⁱ

CCR10 chemokine receptor binding
Source: BHF-UCL
Inferred from direct assayⁱ
- 10706668
CCR chemokine receptor binding
Source: GO_Central
Inferred from biological aspect of ancestorⁱ
- 21873635
chemokine activity
Source: UniProtKB
Inferred from direct assayⁱ
- 18308860
chemokine receptor binding
Source: UniProtKB
Inferred from direct assayⁱ
- 23341447
hormone activity
Source: ProtInc
Traceable author statementⁱ
- 9285413

View the complete GO annotation on QuickGO ...

Protein-protein interaction databases

BioGridⁱ	112273, 3 interactors
Database of interacting proteins More...DIPⁱ	DIP-5883N
IntActⁱ	O15444, 10 interactors
Molecular INTeraction database More...MINTⁱ	O15444
STRINGⁱ	9606.ENSP00000375086

Structureⁱ

3D structure databases

ProteinModelPortalⁱ	O15444
SMRⁱ	O15444
ModBaseⁱ	Search...
MobiDBⁱ	Search...

Family & Domainsⁱ

Sequence similaritiesⁱ

Belongs to the intercrine beta (chemokine CC) family.Curated

Keywords - Domainⁱ

Signal

Phylogenomic databases

eggNOGⁱ	ENOG410J09B Eukaryota ENOG410Z7F2 LUCA
Ensembl GeneTree More...GeneTreeⁱ	ENSGT00900000141238
HOGENOMⁱ	HOG000293281
HOVERGENⁱ	HBG050832
InParanoidⁱ	O15444
KEGG Orthology (KO) More...KOⁱ	K13072
OMAⁱ	CCLAYHR
PhylomeDBⁱ	O15444
TreeFamⁱ	TF353160

Family and domain databases

Conserved Domains Database More...CDDⁱ	cd01119 Chemokine_CC_DCCL, 1 hit
InterProⁱ	View protein in InterPro IPR039809 Chemokine_b/g/d IPR034133 Chemokine_CC_DCCL IPR001811 Chemokine_IL8-like_dom IPR036048 Interleukin_8-like_sf
PANTHERⁱ	PTHR12015 PTHR12015, 1 hit
Pfam protein domain database More...Pfamⁱ	View protein in Pfam PF00048 IL8, 1 hit
SMARTⁱ	View protein in SMART SM00199 SCY, 1 hit
SUPFAMⁱ	SSF54117 SSF54117, 1 hit

Sequences (3+)ⁱ

Sequence statusⁱ: Complete.

Sequence processingⁱ: The displayed sequence is further processed into a mature form.

This entry describes 3 isoformsⁱ produced by alternative splicing. Align Add to basket

This entry has 3 described isoforms and 2 potential isoforms that are computationally mapped.Show all Align All

Isoform 1 (identifier: O15444-1) [UniParc]FASTA Add to basket

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide

        10         20         30         40         50
MNLWLLACLV AGFLGAWAPA VHTQGVFEDC CLAYHYPIGW AVLRRAWTYR 
        60         70         80         90        100
IQEVSGSCNL PAAIFYLPKR HRKVCGNPKS REVQRAMKLL DARNKVFAKL 
       110        120        130        140        150
HHNTQTFQAG PHAVKKLSSG NSKLSSSKFS NPISSSKRNV SLLISANSGL

Length:150

Mass (Da):16,609

Last modified:July 22, 2008 - v2

Checksum:ⁱ91D0810F137FBC7B

GO

Isoform 2 (identifier: O15444-2) [UniParc]FASTA Add to basket

Also known as: TECKvar

The sequence of this isoform differs from the canonical sequence as follows:
65-150: FYLPKRHRKV...SLLISANSGL → RPSCCKEVEFWKLQVIIIQV

« Hide

        10         20         30         40         50
MNLWLLACLV AGFLGAWAPA VHTQGVFEDC CLAYHYPIGW AVLRRAWTYR 
        60         70         80 
IQEVSGSCNL PAAIRPSCCK EVEFWKLQVI IIQV

Note: May be produced at very low levels due to a premature stop codon in the mRNA, leading to nonsense-mediated mRNA decay.

Show »

Length:84

Mass (Da):9,496

Checksum:ⁱ11307E0137B394D4

GO

Isoform 3 (identifier: O15444-3) [UniParc]FASTA Add to basket

The sequence of this isoform differs from the canonical sequence as follows:
109-109: Missing.

« Hide

        10         20         30         40         50
MNLWLLACLV AGFLGAWAPA VHTQGVFEDC CLAYHYPIGW AVLRRAWTYR 
        60         70         80         90        100
IQEVSGSCNL PAAIFYLPKR HRKVCGNPKS REVQRAMKLL DARNKVFAKL 
       110        120        130        140 
HHNTQTFQGP HAVKKLSSGN SKLSSSKFSN PISSSKRNVS LLISANSGL

Show »

Length:149

Mass (Da):16,538

Checksum:ⁱAC5468E6EF71986E

GO

Computationally mapped potential isoform sequencesⁱ

There are 2 potential isoforms mapped to this entry.BLAST Align Show all Add to basket

Entry	Entry name	Protein names	Gene names	Length	Annotation

C9JDZ7	C9JDZ7_HUMAN	C-C motif chemokine 25 C-C motif chemokine 25	CCL25	150	Annotation score:
F8VWI0	F8VWI0_HUMAN	C-C motif chemokine 25 C-C motif chemokine 25	CCL25	84	Annotation score:

Natural variant

Feature key	Position(s)	DescriptionActions	Length
Natural variantⁱVAR_044519	23	T → A. Corresponds to variant dbSNP:rs960173Ensembl.	1
Natural variantⁱVAR_044520	101	H → R. Corresponds to variant dbSNP:rs2032887Ensembl.	1
Natural variantⁱVAR_044521	104	T → M1 PublicationCorresponds to variant dbSNP:rs1129763Ensembl.	1

Alternative sequence

Feature key	Position(s)	DescriptionActions	Graphical view	Length
Alternative sequenceⁱVSP_001064	65 – 150	FYLPK…ANSGL → RPSCCKEVEFWKLQVIIIQV in isoform 2. 1 PublicationAdd BLAST		86
Alternative sequenceⁱVSP_043199	109	Missing in isoform 3. 2 Publications		1

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	U86358 mRNA Translation: AAB69981.1 AB046579 mRNA Translation: BAB62257.1 AK292662 mRNA Translation: BAF85351.1 AC008946 Genomic DNA No translation available. CH471139 Genomic DNA Translation: EAW68952.1 BC130561 mRNA Translation: AAI30562.1 BC144463 mRNA Translation: AAI44464.1
The Consensus CDS (CCDS) project More...CCDSⁱ	CCDS12194.1 [O15444-1] CCDS56080.1 [O15444-3]
NCBI Reference Sequences More...RefSeqⁱ	NP_001188288.1, NM_001201359.1 [O15444-3] NP_005615.2, NM_005624.3 [O15444-1] XP_011526479.1, XM_011528177.2 [O15444-1] XP_016882609.1, XM_017027120.1 [O15444-1] XP_016882610.1, XM_017027121.1 [O15444-1] XP_016882611.1, XM_017027122.1 [O15444-3]
UniGeneⁱ	Hs.310511

Genome annotation databases

Ensemblⁱ	ENST00000253451; ENSP00000253451; ENSG00000131142 [O15444-3] ENST00000390669; ENSP00000375086; ENSG00000131142 [O15444-1]
GeneIDⁱ	6370
KEGGⁱ	hsa:6370
UCSC genome browser More...UCSCⁱ	uc002mjc.5 human [O15444-1]

Keywords - Coding sequence diversityⁱ

Alternative splicing, Polymorphism

Similar proteinsⁱ

90% Identity
50% Identity

Protein	Similar proteins		Species	Score	Length	Source
O15444-2	C-C motif chemokine 25		HUMAN		84	UniRef90_O15444-2
CCL25 isoform 3		PANTR		84
CCL25 isoform 1		PONAB		84
O15444-3	C-C motif chemokine 25		HUMAN		150	UniRef90_O15444-3
C-C motif chemokine ligand 25		PANTR		150
Uncharacterized protein		PANPA		150
C-C motif chemokine ligand 25		PONAB		150
C-C motif chemokine ligand 25		GORGO		150
+4

Protein	Similar proteins		Species	Score	Length	Source
O15444	C-C motif chemokine ligand 25		SAIBB		149	UniRef50_O15444
Uncharacterized protein		PAPAN		215
Uncharacterized protein		CERAT		172
UPI0007DC6459		HUMAN		210
UPI0008403DAD		CALJA		172
+7
O15444-2	C-C motif chemokine 25		HUMAN		84	UniRef50_O15444-2
CCL25 isoform 3		PANTR		84
CCL25 isoform 1		PONAB		84
UPI00032AD4A7		OCHPR		105
O15444-3	C-C motif chemokine ligand 25		GORGO		150	UniRef50_O15444-3
CCL25 isoform 4 (Fragment)		PANTR		150
CCL25 isoform 4 (Fragment)		PONAB		150
C-C motif chemokine 25		HUMAN		150
Uncharacterized protein		PANPA		150
+14

Cross-referencesⁱ

Web resourcesⁱ

Wikipedia

CCL25 entry

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	U86358 mRNA Translation: AAB69981.1 AB046579 mRNA Translation: BAB62257.1 AK292662 mRNA Translation: BAF85351.1 AC008946 Genomic DNA No translation available. CH471139 Genomic DNA Translation: EAW68952.1 BC130561 mRNA Translation: AAI30562.1 BC144463 mRNA Translation: AAI44464.1
CCDSⁱ	CCDS12194.1 [O15444-1] CCDS56080.1 [O15444-3]
RefSeqⁱ	NP_001188288.1, NM_001201359.1 [O15444-3] NP_005615.2, NM_005624.3 [O15444-1] XP_011526479.1, XM_011528177.2 [O15444-1] XP_016882609.1, XM_017027120.1 [O15444-1] XP_016882610.1, XM_017027121.1 [O15444-1] XP_016882611.1, XM_017027122.1 [O15444-3]
UniGeneⁱ	Hs.310511

3D structure databases

ProteinModelPortalⁱ	O15444
SMRⁱ	O15444
ModBaseⁱ	Search...
MobiDBⁱ	Search...

Protein-protein interaction databases

BioGridⁱ	112273, 3 interactors
DIPⁱ	DIP-5883N
IntActⁱ	O15444, 10 interactors
MINTⁱ	O15444
STRINGⁱ	9606.ENSP00000375086

PTM databases

iPTMnetⁱ	O15444
PhosphoSitePlusⁱ	O15444

Polymorphism and mutation databases

BioMutaⁱ	CCL25

BioMutaⁱ

CCL25

Proteomic databases

PaxDbⁱ	O15444
PRIDEⁱ	O15444
ProteomicsDBⁱ	48672 48673 [O15444-2] 48674 [O15444-3]

Protocols and materials databases

The DNASU plasmid repository More...DNASUⁱ	6370
Structural Biology Knowledgebase	Search...

Genome annotation databases

Ensemblⁱ	ENST00000253451; ENSP00000253451; ENSG00000131142 [O15444-3] ENST00000390669; ENSP00000375086; ENSG00000131142 [O15444-1]
GeneIDⁱ	6370
KEGGⁱ	hsa:6370
UCSCⁱ	uc002mjc.5 human [O15444-1]

Organism-specific databases

CTDⁱ	6370
DisGeNETⁱ	6370
EuPathDBⁱ	HostDB:ENSG00000131142.13
GeneCardsⁱ	CCL25
H-InvDBⁱ	HIX0039931
HGNCⁱ	HGNC:10624 CCL25
HPAⁱ	HPA055883
MIMⁱ	602565 gene
neXtProtⁱ	NX_O15444
OpenTargetsⁱ	ENSG00000131142
PharmGKBⁱ	PA35556
GenAtlas: human gene database More...GenAtlasⁱ	Search...

Phylogenomic databases

eggNOGⁱ	ENOG410J09B Eukaryota ENOG410Z7F2 LUCA
GeneTreeⁱ	ENSGT00900000141238
HOGENOMⁱ	HOG000293281
HOVERGENⁱ	HBG050832
InParanoidⁱ	O15444
KOⁱ	K13072
OMAⁱ	CCLAYHR
PhylomeDBⁱ	O15444
TreeFamⁱ	TF353160

Enzyme and pathway databases

Reactomeⁱ	R-HSA-380108 Chemokine receptors bind chemokines R-HSA-418594 G alpha (i) signalling events
SIGNORⁱ	O15444

Miscellaneous databases

GenomeRNAiⁱ	6370
Protein Ontology More...PROⁱ	PR:O15444
SOURCEⁱ	Search...

Gene expression databases

Bgeeⁱ	ENSG00000131142 Expressed in 59 organ(s), highest expression level in intestine
CleanExⁱ	HS_CCL25
ExpressionAtlasⁱ	O15444 baseline and differential
Genevisibleⁱ	O15444 HS

Family and domain databases

CDDⁱ	cd01119 Chemokine_CC_DCCL, 1 hit
InterProⁱ	View protein in InterPro IPR039809 Chemokine_b/g/d IPR034133 Chemokine_CC_DCCL IPR001811 Chemokine_IL8-like_dom IPR036048 Interleukin_8-like_sf
PANTHERⁱ	PTHR12015 PTHR12015, 1 hit
Pfamⁱ	View protein in Pfam PF00048 IL8, 1 hit
SMARTⁱ	View protein in SMART SM00199 SCY, 1 hit
SUPFAMⁱ	SSF54117 SSF54117, 1 hit
ProtoNetⁱ	Search...

Entry informationⁱ

Entry nameⁱ	CCL25_HUMAN
Accessionⁱ	O15444Primary (citable) accession number: O15444 Secondary accession number(s): A1L4J4 , A6NI52, A8K9E7, B5MCA5, Q96KJ7
Entry historyⁱ	Integrated into UniProtKB/Swiss-Prot:	July 15, 1998
	Last sequence update:	July 22, 2008
	Last modified:	November 7, 2018
	This is version 145 of the entry and version 2 of the sequence. See complete history.
Entry statusⁱ	Reviewed (UniProtKB/Swiss-Prot)
Annotation program	Chordata Protein Annotation Program
Disclaimer	Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousⁱ

Keywords - Technical termⁱ

Complete proteome, Reference proteome

Documents

SIMILARITY comments
Index of protein domains and families
Human entries with polymorphisms or disease mutations
List of human entries with polymorphisms or disease mutations
Human polymorphisms and disease mutations
Index of human polymorphisms and disease mutations
MIM cross-references
Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
Human chromosome 19
Human chromosome 19: entries, gene names and cross-references to MIM

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Supporting data

UniProtKB - O15444 (CCL25_HUMAN)

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C-C motif chemokine 25

Select a section on the left to see content.

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

Enzyme and pathway databases

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

Organism-specific databases

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted

Extracellular region or secreted

Keywords - Cellular componenti

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

Polymorphism and mutation databases

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Amino acid modifications

Keywords - PTMi

Proteomic databases

PTM databases

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Organism-specific databases

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

GO - Molecular functioni

Protein-protein interaction databases

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

<p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Keywords - Domaini

Phylogenomic databases

Family and domain databases

Natural variant

Alternative sequence

Sequence databases

Genome annotation databases

Keywords - Coding sequence diversityi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

<p>This subsection of the <a href="http://www.uniprot.org/manual/cross_references_section">Cross-references</a> section provides links to various web resources that are relevant for a specific protein.<p><a href='/help/web_resource' target='_top'>More...</a></p>Web resourcesi

Sequence databases

3D structure databases

Protein-protein interaction databases

PTM databases

Polymorphism and mutation databases

Proteomic databases

Protocols and materials databases

Genome annotation databases

Organism-specific databases

Phylogenomic databases

Enzyme and pathway databases

Miscellaneous databases

Gene expression databases

Family and domain databases

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Documents

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Functionⁱ

GO - Molecular functionⁱ

GO - Biological processⁱ

Names & Taxonomyⁱ

Subcellular locationⁱ

Keywords - Cellular componentⁱ

Pathology & Biotechⁱ

PTM / Processingⁱ

Keywords - PTMⁱ

Expressionⁱ

Interactionⁱ

GO - Molecular functionⁱ

Structureⁱ

Family & Domainsⁱ

Sequence similaritiesⁱ

Keywords - Domainⁱ

Keywords - Coding sequence diversityⁱ

Cross-referencesⁱ

Web resourcesⁱ

Entry informationⁱ

Miscellaneousⁱ

Keywords - Technical termⁱ