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Entry version 159 (12 Aug 2020)
Sequence version 1 (01 Jan 1998)
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Protein

BET1 homolog

Gene

BET1

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Required for vesicular transport from the ER to the Golgi complex. Functions as a SNARE involved in the docking process of ER-derived vesicles with the cis-Golgi membrane (By similarity).By similarity

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Biological processER-Golgi transport, Protein transport, Transport

Enzyme and pathway databases

Pathway Commons web resource for biological pathway data

More...
PathwayCommonsi
O15155

Reactome - a knowledgebase of biological pathways and processes

More...
Reactomei
R-HSA-204005, COPII-mediated vesicle transport
R-HSA-6807878, COPI-mediated anterograde transport

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
BET1 homolog
Short name:
hBET1
Alternative name(s):
Golgi vesicular membrane-trafficking protein p18
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:BET1
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 7

Organism-specific databases

Eukaryotic Pathogen Database Resources

More...
EuPathDBi
HostDB:ENSG00000105829.11

Human Gene Nomenclature Database

More...
HGNCi
HGNC:14562, BET1

Online Mendelian Inheritance in Man (OMIM)

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MIMi
605456, gene

neXtProt; the human protein knowledge platform

More...
neXtProti
NX_O15155

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/subcellular%5Flocation%5Fsection">'Subcellular location'</a> section describes the subcellular compartment where each non-membrane region of a membrane-spanning protein is found.<p><a href='/help/topo_dom' target='_top'>More...</a></p>Topological domaini1 – 94CytoplasmicSequence analysisAdd BLAST94
<p>This subsection of the <a href="http://www.uniprot.org/help/subcellular%5Flocation%5Fsection">'Subcellular location'</a> section describes the extent of a membrane-spanning region of the protein. It denotes the presence of both alpha-helical transmembrane regions and the membrane spanning regions of beta-barrel transmembrane proteins.<p><a href='/help/transmem' target='_top'>More...</a></p>Transmembranei95 – 115Helical; Anchor for type IV membrane proteinSequence analysisAdd BLAST21
Topological domaini116 – 118VesicularSequence analysis3

Keywords - Cellular componenti

Endoplasmic reticulum, Golgi apparatus, Membrane

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

DisGeNET

More...
DisGeNETi
10282

Open Targets

More...
OpenTargetsi
ENSG00000105829

The Pharmacogenetics and Pharmacogenomics Knowledge Base

More...
PharmGKBi
PA25338

Miscellaneous databases

Pharos NIH Druggable Genome Knowledgebase

More...
Pharosi
O15155, Tdark

Polymorphism and mutation databases

BioMuta curated single-nucleotide variation and disease association database

More...
BioMutai
BET1

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00002068841 – 118BET1 homologAdd BLAST118

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section specifies the position and type of each modified residue excluding <a href="http://www.uniprot.org/manual/lipid">lipids</a>, <a href="http://www.uniprot.org/manual/carbohyd">glycans</a> and <a href="http://www.uniprot.org/manual/crosslnk">protein cross-links</a>.<p><a href='/help/mod_res' target='_top'>More...</a></p>Modified residuei50PhosphoserineCombined sources1

Keywords - PTMi

Phosphoprotein

Proteomic databases

Encyclopedia of Proteome Dynamics

More...
EPDi
O15155

jPOST - Japan Proteome Standard Repository/Database

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jPOSTi
O15155

MassIVE - Mass Spectrometry Interactive Virtual Environment

More...
MassIVEi
O15155

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
O15155

PeptideAtlas

More...
PeptideAtlasi
O15155

PRoteomics IDEntifications database

More...
PRIDEi
O15155

ProteomicsDB: a multi-organism proteome resource

More...
ProteomicsDBi
48479 [O15155-1]
76387

Consortium for Top Down Proteomics

More...
TopDownProteomicsi
O15155-1 [O15155-1]

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
O15155

MetOSite database of methionine sulfoxide sites

More...
MetOSitei
O15155

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...
PhosphoSitePlusi
O15155

SwissPalm database of S-palmitoylation events

More...
SwissPalmi
O15155

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

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Bgeei
ENSG00000105829, Expressed in testis and 233 other tissues

ExpressionAtlas, Differential and Baseline Expression

More...
ExpressionAtlasi
O15155, baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

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Genevisiblei
O15155, HS

Organism-specific databases

Human Protein Atlas

More...
HPAi
ENSG00000105829, Low tissue specificity

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the <a href="http://www.uniprot.org/help/interaction%5Fsection">'Interaction'</a> section provides information about the protein quaternary structure and interaction(s) with other proteins or protein complexes (with the exception of physiological receptor-ligand interactions which are annotated in the <a href="http://www.uniprot.org/help/function%5Fsection">'Function'</a> section).<p><a href='/help/subunit_structure' target='_top'>More...</a></p>Subunit structurei

Interacts with STX17.

By similarity

<p>This subsection of the '<a href="http://www.uniprot.org/help/interaction%5Fsection">Interaction</a>' section provides information about binary protein-protein interactions. The data presented in this section are a quality-filtered subset of binary interactions automatically derived from the <a href="https://www.ebi.ac.uk/intact/">IntAct database</a>. It is updated at every <a href="http://www.uniprot.org/help/synchronization">UniProt release</a>.<p><a href='/help/binary_interactions' target='_top'>More...</a></p>Binary interactionsi

Hide details
O15155
With#Exp.IntAct
ADORA2A [P29274]3EBI-749204,EBI-2902702
ANKS6 [Q68DC2]3EBI-749204,EBI-7054139
AQP6 [Q13520]3EBI-749204,EBI-13059134
ASGR2 - isoform 3 [P07307-3]3EBI-749204,EBI-12808270
ASZ1 [Q8WWH4]3EBI-749204,EBI-12239061
CCDC155 [Q8N6L0]3EBI-749204,EBI-749265
CD74 - isoform 2 [P04233-2]3EBI-749204,EBI-12222807
CD79A [P11912]3EBI-749204,EBI-7797864
CGRRF1 [Q99675]3EBI-749204,EBI-2130213
CISD2 [Q8N5K1]3EBI-749204,EBI-1045797
CLDN7 [O95471]3EBI-749204,EBI-740744
CLEC10A [Q8IUN9]3EBI-749204,EBI-2873246
CRB3 - isoform 2 [Q9BUF7-2]3EBI-749204,EBI-17233035
CREB3L1 [Q96BA8]3EBI-749204,EBI-6942903
CYB561 [P49447]3EBI-749204,EBI-8646596
CYBC1 [Q9BQA9]3EBI-749204,EBI-2680384
ELOVL4 [Q9GZR5]3EBI-749204,EBI-18535450
ERGIC3 [Q9Y282]3EBI-749204,EBI-781551
FAM174A [Q8TBP5]3EBI-749204,EBI-18636064
FAM209A [Q5JX71]3EBI-749204,EBI-18304435
FAM210B [Q96KR6]3EBI-749204,EBI-18938272
GOSR2 [O14653]5EBI-749204,EBI-4401517
GPR152 [Q8TDT2]3EBI-749204,EBI-13345167
GPX8 [Q8TED1]3EBI-749204,EBI-11721746
JAGN1 [Q8N5M9]3EBI-749204,EBI-10266796
KCNJ6 [P48051]3EBI-749204,EBI-12017638
LYPD5 [Q6UWN5]3EBI-749204,EBI-17200970
MAGEA6 [P43360]3EBI-749204,EBI-1045155
MFF - isoform 5 [Q9GZY8-5]3EBI-749204,EBI-11956541
MGST3 [O14880]3EBI-749204,EBI-724754
NAPB [Q9H115]3EBI-749204,EBI-3921185
PTGES [O14684]3EBI-749204,EBI-11161398
REEP4 [Q9H6H4]3EBI-749204,EBI-7545592
RETREG3 [Q86VR2]3EBI-749204,EBI-10192441
SLC26A6 - isoform 3 [Q9BXS9-3]3EBI-749204,EBI-12814225
SLC7A14 [Q8TBB6]3EBI-749204,EBI-5235586
SSMEM1 [Q8WWF3]3EBI-749204,EBI-17280858
STX1A [Q16623]3EBI-749204,EBI-712466
STX1B [P61266]3EBI-749204,EBI-9071709
STX2 - isoform 1 [P32856-2]3EBI-749204,EBI-11956649
STX4 [Q12846]6EBI-749204,EBI-744942
TMCO5A [Q8N6Q1]3EBI-749204,EBI-12821895
TMEM237 - isoform 2 [Q96Q45-2]3EBI-749204,EBI-10982110
TMEM35A [Q53FP2]3EBI-749204,EBI-11722971
TMEM52B [Q4KMG9]3EBI-749204,EBI-18178701
TMEM80 [Q96HE8]3EBI-749204,EBI-11742770
TMX2 [Q9Y320]3EBI-749204,EBI-6447886
USHBP1 [Q8N6Y0]2EBI-749204,EBI-739895

GO - Molecular functioni

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGRID)

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BioGRIDi
115571, 282 interactors

Protein interaction database and analysis system

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IntActi
O15155, 317 interactors

Molecular INTeraction database

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MINTi
O15155

STRING: functional protein association networks

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STRINGi
9606.ENSP00000222547

Miscellaneous databases

RNAct, Protein-RNA interaction predictions for model organisms.

More...
RNActi
O15155, protein

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

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SMRi
O15155

Database of comparative protein structure models

More...
ModBasei
Search...

Protein Data Bank in Europe - Knowledge Base

More...
PDBe-KBi
Search...

Miscellaneous databases

Relative evolutionary importance of amino acids within a protein sequence

More...
EvolutionaryTracei
O15155

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family%5Fand%5Fdomains%5Fsection">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini26 – 88t-SNARE coiled-coil homologyPROSITE-ProRule annotationAdd BLAST63

<p>This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the BET1 family.Curated

Keywords - Domaini

Coiled coil, Transmembrane, Transmembrane helix

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

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eggNOGi
KOG3385, Eukaryota

Ensembl GeneTree

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GeneTreei
ENSGT00940000162637

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
CLU_086133_2_1_1

InParanoid: Eukaryotic Ortholog Groups

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InParanoidi
O15155

KEGG Orthology (KO)

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KOi
K08504

Database for complete collections of gene phylogenies

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PhylomeDBi
O15155

TreeFam database of animal gene trees

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TreeFami
TF323307

Family and domain databases

Conserved Domains Database

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CDDi
cd15853, SNARE_Bet1, 1 hit

Integrated resource of protein families, domains and functional sites

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InterProi
View protein in InterPro
IPR039897, BET1
IPR039899, BET1_SNARE
IPR000727, T_SNARE_dom

The PANTHER Classification System

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PANTHERi
PTHR12791, PTHR12791, 1 hit

Simple Modular Architecture Research Tool; a protein domain database

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SMARTi
View protein in SMART
SM00397, t_SNARE, 1 hit

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS50192, T_SNARE, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequences (2+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry describes 2 <p>This subsection of the 'Sequence' section lists the alternative protein sequences (isoforms) that can be generated from the same gene by a single or by the combination of up to four biological events (alternative promoter usage, alternative splicing, alternative initiation and ribosomal frameshifting). Additionally, this section gives relevant information on each alternative protein isoform. This section is only present in reviewed entries, i.e. in UniProtKB/Swiss-Prot.<p><a href='/help/alternative_products' target='_top'>More...</a></p> isoformsi produced by alternative splicing. AlignAdd to basket

This entry has 2 described isoforms and 4 potential isoforms that are computationally mapped.Show allAlign All

Isoform 1 (identifier: O15155-1) [UniParc]FASTAAdd to basket

This isoform has been chosen as the <div> <p><b>What is the canonical sequence?</b><p><a href='/help/canonical_and_isoforms' target='_top'>More...</a></p>canonicali sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide
        10         20         30         40         50
MRRAGLGEGV PPGNYGNYGY ANSGYSACEE ENERLTESLR SKVTAIKSLS
60 70 80 90 100
IEIGHEVKTQ NKLLAEMDSQ FDSTTGFLGK TMGKLKILSR GSQTKLLCYM
110
MLFSLFVFFI IYWIIKLR
Length:118
Mass (Da):13,289
Last modified:January 1, 1998 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iB83B76ACBB3DA57E
GO
Isoform 2 (identifier: O15155-2) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     80-118: KTMGKLKILSRGSQTKLLCYMMLFSLFVFFIIYWIIKLR → LCPM

Show »
Length:83
Mass (Da):9,020
Checksum:i71D35D46B020CD54
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There are 4 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
H7C1N3H7C1N3_HUMAN
BET1 homolog
BET1
133Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
Q68DU7Q68DU7_HUMAN
BET1 homolog
BET1 DKFZp781C0425
127Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
C9JTT8C9JTT8_HUMAN
BET1 homolog
BET1
98Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A3B3IU16A0A3B3IU16_HUMAN
BET1 homolog
BET1
85Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

Alternative sequence

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section describes the sequence of naturally occurring alternative protein isoform(s). The changes in the amino acid sequence may be due to alternative splicing, alternative promoter usage, alternative initiation, or ribosomal frameshifting.<p><a href='/help/var_seq' target='_top'>More...</a></p>Alternative sequenceiVSP_05621680 – 118KTMGK…IIKLR → LCPM in isoform 2. 1 PublicationAdd BLAST39

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

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GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AF007551 mRNA Translation: AAB62941.1
AC006378 Genomic DNA Translation: AAD47132.1
CH471091 Genomic DNA Translation: EAW76802.1
BC000899 mRNA Translation: AAH00899.1
BC012595 mRNA Translation: AAH12595.1

The Consensus CDS (CCDS) project

More...
CCDSi
CCDS5635.1 [O15155-1]
CCDS83203.1 [O15155-2]

NCBI Reference Sequences

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RefSeqi
NP_001304668.1, NM_001317739.1 [O15155-2]
NP_005859.1, NM_005868.5 [O15155-1]

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENST00000222547; ENSP00000222547; ENSG00000105829 [O15155-1]
ENST00000433727; ENSP00000391228; ENSG00000105829 [O15155-2]

Database of genes from NCBI RefSeq genomes

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GeneIDi
10282

KEGG: Kyoto Encyclopedia of Genes and Genomes

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KEGGi
hsa:10282

UCSC genome browser

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UCSCi
uc064fkr.1, human [O15155-1]

Keywords - Coding sequence diversityi

Alternative splicing

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF007551 mRNA Translation: AAB62941.1
AC006378 Genomic DNA Translation: AAD47132.1
CH471091 Genomic DNA Translation: EAW76802.1
BC000899 mRNA Translation: AAH00899.1
BC012595 mRNA Translation: AAH12595.1
CCDSiCCDS5635.1 [O15155-1]
CCDS83203.1 [O15155-2]
RefSeqiNP_001304668.1, NM_001317739.1 [O15155-2]
NP_005859.1, NM_005868.5 [O15155-1]

3D structure databases

Select the link destinations:

Protein Data Bank Europe

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PDBei

Protein Data Bank RCSB

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RCSB PDBi

Protein Data Bank Japan

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PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
3EGXX-ray3.30D24-32[»]
SMRiO15155
ModBaseiSearch...
PDBe-KBiSearch...

Protein-protein interaction databases

BioGRIDi115571, 282 interactors
IntActiO15155, 317 interactors
MINTiO15155
STRINGi9606.ENSP00000222547

PTM databases

iPTMnetiO15155
MetOSiteiO15155
PhosphoSitePlusiO15155
SwissPalmiO15155

Polymorphism and mutation databases

BioMutaiBET1

Proteomic databases

EPDiO15155
jPOSTiO15155
MassIVEiO15155
PaxDbiO15155
PeptideAtlasiO15155
PRIDEiO15155
ProteomicsDBi48479 [O15155-1]
76387
TopDownProteomicsiO15155-1 [O15155-1]

Protocols and materials databases

Antibodypedia a portal for validated antibodies

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Antibodypediai
64131, 38 antibodies

The DNASU plasmid repository

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DNASUi
10282

Genome annotation databases

EnsembliENST00000222547; ENSP00000222547; ENSG00000105829 [O15155-1]
ENST00000433727; ENSP00000391228; ENSG00000105829 [O15155-2]
GeneIDi10282
KEGGihsa:10282
UCSCiuc064fkr.1, human [O15155-1]

Organism-specific databases

Comparative Toxicogenomics Database

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CTDi
10282
DisGeNETi10282
EuPathDBiHostDB:ENSG00000105829.11

GeneCards: human genes, protein and diseases

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GeneCardsi
BET1
HGNCiHGNC:14562, BET1
HPAiENSG00000105829, Low tissue specificity
MIMi605456, gene
neXtProtiNX_O15155
OpenTargetsiENSG00000105829
PharmGKBiPA25338

GenAtlas: human gene database

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GenAtlasi
Search...

Phylogenomic databases

eggNOGiKOG3385, Eukaryota
GeneTreeiENSGT00940000162637
HOGENOMiCLU_086133_2_1_1
InParanoidiO15155
KOiK08504
PhylomeDBiO15155
TreeFamiTF323307

Enzyme and pathway databases

PathwayCommonsiO15155
ReactomeiR-HSA-204005, COPII-mediated vesicle transport
R-HSA-6807878, COPI-mediated anterograde transport

Miscellaneous databases

BioGRID ORCS database of CRISPR phenotype screens

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BioGRID-ORCSi
10282, 307 hits in 853 CRISPR screens

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

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ChiTaRSi
BET1, human
EvolutionaryTraceiO15155

The Gene Wiki collection of pages on human genes and proteins

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GeneWikii
BET1

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

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GenomeRNAii
10282
PharosiO15155, Tdark

Protein Ontology

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PROi
PR:O15155
RNActiO15155, protein

The Stanford Online Universal Resource for Clones and ESTs

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SOURCEi
Search...

Gene expression databases

BgeeiENSG00000105829, Expressed in testis and 233 other tissues
ExpressionAtlasiO15155, baseline and differential
GenevisibleiO15155, HS

Family and domain databases

CDDicd15853, SNARE_Bet1, 1 hit
InterProiView protein in InterPro
IPR039897, BET1
IPR039899, BET1_SNARE
IPR000727, T_SNARE_dom
PANTHERiPTHR12791, PTHR12791, 1 hit
SMARTiView protein in SMART
SM00397, t_SNARE, 1 hit
PROSITEiView protein in PROSITE
PS50192, T_SNARE, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

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ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

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MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiBET1_HUMAN
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: O15155
Secondary accession number(s): Q96EA0
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: January 17, 2003
Last sequence update: January 1, 1998
Last modified: August 12, 2020
This is version 159 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

3D-structure, Reference proteome

Documents

  1. Human chromosome 7
    Human chromosome 7: entries, gene names and cross-references to MIM
  2. MIM cross-references
    Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
  3. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  4. SIMILARITY comments
    Index of protein domains and families
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