UniProtKB - O15120 (PLCB_HUMAN)
Protein
1-acyl-sn-glycerol-3-phosphate acyltransferase beta
Gene
AGPAT2
Organism
Homo sapiens (Human)
Status
Functioni
Converts 1-acyl-sn-glycerol-3-phosphate (lysophosphatidic acid or LPA) into 1,2-diacyl-sn-glycerol-3-phosphate (phosphatidic acid or PA) by incorporating an acyl moiety at the sn-2 position of the glycerol backbone.4 Publications
Catalytic activityi
- a 1-acyl-sn-glycero-3-phosphate + an acyl-CoA = a 1,2-diacyl-sn-glycero-3-phosphate + CoA4 PublicationsEC:2.3.1.514 PublicationsThis reaction proceeds in the forward4 Publications direction.
- (9Z)-octadecenoyl-CoA + 1-(9Z-octadecenoyl)-sn-glycero-3-phosphate = 1,2-di-(9Z-octadecenoyl)-sn-glycero-3-phosphate + CoA2 PublicationsThis reaction proceeds in the forward2 Publications direction.
- 1-(9Z-octadecenoyl)-sn-glycero-3-phosphate + hexadecanoyl-CoA = 1-(9Z)-octadecenoyl-2-hexadecanoyl-sn-glycero-3-phosphate + CoA1 PublicationThis reaction proceeds in the forward1 Publication direction.
- 1-(9Z-octadecenoyl)-sn-glycero-3-phosphate + heptadecanoyl-CoA = 1-(9Z)-octadecenoyl-2-heptadecanoyl-sn-glycero-3-phosphate + CoA1 PublicationThis reaction proceeds in the forward1 Publication direction.
- (9Z,12Z)-octadecadienoyl-CoA + 1-(9Z-octadecenoyl)-sn-glycero-3-phosphate = 1-(9Z)-octadecenoyl-2-(9Z,12Z)-octadecadienoyl-sn-glycero-3-phosphate + CoA1 PublicationThis reaction proceeds in the forward1 Publication direction.
- 1-(9Z-octadecenoyl)-sn-glycero-3-phosphate + tetradecanoyl-CoA = 1-(9Z)-octadecenoyl-2-tetradecanoyl-sn-glycero-3-phosphate + CoA1 PublicationThis reaction proceeds in the forward1 Publication direction.
- 1-(9Z-octadecenoyl)-sn-glycero-3-phosphate + pentadecanoyl-CoA = 1-(9Z)-octadecenoyl-2-pentadecanoyl-sn-glycero-3-phosphate + CoA1 PublicationThis reaction proceeds in the forward1 Publication direction.
- (9Z)-octadecenoyl-CoA + 1-hexadecanoyl-sn-glycero-3-phosphate = 1-hexadecanoyl-2-(9Z-octadecenoyl)-sn-glycero-3-phosphate + CoA1 PublicationThis reaction proceeds in the forward1 Publication direction.
- (9Z)-octadecenoyl-CoA + 1-tetradecanoyl-sn-glycerol 3-phosphate = 1-tetradecanoyl-2-(9Z)-octadecenoyl-sn-glycero-3-phosphate + CoA1 PublicationThis reaction proceeds in the forward1 Publication direction.
- (9Z)-octadecenoyl-CoA + 1-(9Z,12Z,15Z)-octadecatrienoyl-sn-glycero-3-phosphate = 1-(9Z,12Z,15Z)-octadecatrienoyl-2-(9Z)-octadecenoyl-sn-glycero-3-phosphate + CoA1 PublicationThis reaction proceeds in the forward1 Publication direction.
- (9Z)-octadecenoyl-CoA + 1-(6Z,9Z,12Z-octadecatrienoyl)-sn-glycero-3-phosphate = (6Z,9Z,12Z)-octadecatrienoyl-2-(9Z)-octadecenoyl-sn-glycero-3-phosphate + CoA1 PublicationThis reaction proceeds in the forward1 Publication direction.
- (9Z)-octadecenoyl-CoA + 1-eicosanoyl-sn-glycero-3-phosphate = 1-eicosanoyl-2-(9Z)-octadecenoyl-sn-glycero-3-phosphate + CoA1 PublicationThis reaction proceeds in the forward1 Publication direction.
- 1-hexadecanoyl-sn-glycero-3-phosphate + octadecanoyl-CoA = 1-hexadecanoyl-2-octadecanoyl-sn-glycero-3-phosphate + CoA1 PublicationThis reaction proceeds in the forward1 Publication direction.
- (5Z,8Z,11Z,14Z)-eicosatetraenoyl-CoA + 1-hexadecanoyl-sn-glycero-3-phosphate = 1-hexadecanoyl-2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phosphate + CoA1 PublicationThis reaction proceeds in the forward1 Publication direction.
- 1-hexadecanoyl-sn-glycero-3-phosphate + hexadecanoyl-CoA = 1,2-dihexadecanoyl-sn-glycero-3-phosphate + CoA1 PublicationThis reaction proceeds in the forward1 Publication direction.
- 1-hexadecanoyl-sn-glycero-3-phosphate + tetradecanoyl-CoA = 1-hexadecanoyl-2-tetradecanoyl-sn-glycero-3-phosphate + CoA1 PublicationThis reaction proceeds in the forward1 Publication direction.
- (11Z)-octadecenoyl-CoA + 1-(9Z-octadecenoyl)-sn-glycero-3-phosphate = 1-(9Z)-octadecenoyl-2-(11Z)-octadecenoyl-sn-glycero-3-phosphate + CoA1 PublicationThis reaction proceeds in the forward1 Publication direction.
Kineticsi
- KM=11.05 µM for C15:0-CoA1 Publication
- KM=523.97 µM for C18:0-CoA1 Publication
- KM=30.21 µM for C18:1-CoA1 Publication
- KM=8.29 µM for LPA sn-1 C18:11 Publication
- Vmax=51.61 nmol/min/mg enzyme for C15:0-CoA1 Publication
- Vmax=95.55 nmol/min/mg enzyme for C18:0-CoA1 Publication
- Vmax=73.81 nmol/min/mg enzyme for C18:1-CoA1 Publication
- Vmax=86.05 nmol/min/mg enzyme for LPA sn-1 C18:11 Publication
: CDP-diacylglycerol biosynthesis Pathwayi
This protein is involved in step 2 of the subpathway that synthesizes CDP-diacylglycerol from sn-glycerol 3-phosphate.Proteins known to be involved in the 3 steps of the subpathway in this organism are:
- Glycerol-3-phosphate acyltransferase 1, mitochondrial, Glycerol-3-phosphate acyltransferase 2, mitochondrial (GPAT2), Glycerol-3-phosphate acyltransferase 1, mitochondrial (GPAM), Glycerol-3-phosphate acyltransferase 1, mitochondrial (GPAM), Glycerol-3-phosphate acyltransferase 1, mitochondrial (DKFZp451B1115), Glycerol-3-phosphate acyltransferase 1, mitochondrial (GPAM), Glycerol-3-phosphate acyltransferase 4 (GPAT4), Glycerol-3-phosphate acyltransferase 3 (GPAT3)
- 1-acyl-sn-glycerol-3-phosphate acyltransferase epsilon (AGPAT5), 1-acyl-sn-glycerol-3-phosphate acyltransferase gamma (AGPAT3), 1-acyl-sn-glycerol-3-phosphate acyltransferase alpha (AGPAT1), 1-acyl-sn-glycerol-3-phosphate acyltransferase beta (AGPAT2), Lysocardiolipin acyltransferase 1 (LCLAT1), 1-acyl-sn-glycerol-3-phosphate acyltransferase delta (AGPAT4)
- Phosphatidate cytidylyltransferase 1 (CDS1), Phosphatidate cytidylyltransferase 2 (CDS2), Phosphatidate cytidylyltransferase, mitochondrial (TAMM41), CDP-diacylglycerol synthase (TAMM41), CDP-diacylglycerol synthase (TAMM41), Phosphatidate cytidylyltransferase (CDS1), Phosphatidate cytidylyltransferase, Phosphatidate cytidylyltransferase, Phosphatidate cytidylyltransferase, CDP-diacylglycerol synthase (TAMM41), CDP-diacylglycerol synthase (TAMM41), Phosphatidate cytidylyltransferase
View all proteins of this organism that are known to be involved in the subpathway that synthesizes CDP-diacylglycerol from sn-glycerol 3-phosphate, the pathway CDP-diacylglycerol biosynthesis and in Phospholipid metabolism.
GO - Molecular functioni
- 1-acylglycerol-3-phosphate O-acyltransferase activity Source: UniProtKB
GO - Biological processi
- CDP-diacylglycerol biosynthetic process Source: UniProtKB-UniPathway
- epidermis development Source: Ensembl
- neutrophil degranulation Source: Reactome
- phosphatidic acid biosynthetic process Source: BHF-UCL
- phospholipid metabolic process Source: UniProtKB
- positive regulation of cytokine-mediated signaling pathway Source: BHF-UCL
- positive regulation of cytokine production Source: BHF-UCL
- response to drug Source: Ensembl
Keywordsi
Molecular function | Acyltransferase, Transferase |
Biological process | Lipid biosynthesis, Lipid metabolism, Phospholipid biosynthesis, Phospholipid metabolism |
Enzyme and pathway databases
BioCyci | MetaCyc:HS09990-MONOMER |
BRENDAi | 2.3.1.51, 2681 |
PathwayCommonsi | O15120 |
Reactomei | R-HSA-1483166, Synthesis of PA R-HSA-6798695, Neutrophil degranulation |
UniPathwayi | UPA00557;UER00613 |
Chemistry databases
SwissLipidsi | SLP:000000096 |
Names & Taxonomyi
Protein namesi | Recommended name: 1-acyl-sn-glycerol-3-phosphate acyltransferase beta (EC:2.3.1.514 Publications)Alternative name(s): 1-acylglycerol-3-phosphate O-acyltransferase 2 Short name: 1-AGP acyltransferase 2 Short name: 1-AGPAT 2 Lysophosphatidic acid acyltransferase beta1 Publication Short name: LPAAT-beta |
Gene namesi | Name:AGPAT2 |
Organismi | Homo sapiens (Human) |
Taxonomic identifieri | 9606 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo |
Proteomesi |
|
Organism-specific databases
EuPathDBi | HostDB:ENSG00000169692.12 |
HGNCi | HGNC:325, AGPAT2 |
MIMi | 603100, gene |
neXtProti | NX_O15120 |
Subcellular locationi
Endoplasmic reticulum
- Endoplasmic reticulum membrane 1 Publication; Multi-pass membrane protein Sequence analysis
Endoplasmic reticulum
- endoplasmic reticulum Source: UniProtKB
- endoplasmic reticulum membrane Source: Reactome
Plasma Membrane
- plasma membrane Source: Reactome
Other locations
- integral component of membrane Source: UniProtKB-KW
- specific granule membrane Source: Reactome
Topology
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Topological domaini | 24 – 29 | LumenalCurated | 6 | |
Transmembranei | 30 – 50 | HelicalSequence analysisAdd BLAST | 21 | |
Topological domaini | 51 – 121 | CytoplasmicCuratedAdd BLAST | 71 | |
Transmembranei | 122 – 142 | HelicalSequence analysisAdd BLAST | 21 | |
Topological domaini | 143 – 278 | LumenalCuratedAdd BLAST | 136 |
Keywords - Cellular componenti
Endoplasmic reticulum, MembranePathology & Biotechi
Involvement in diseasei
Congenital generalized lipodystrophy 1 (CGL1)2 Publications
The disease is caused by mutations affecting the gene represented in this entry.
Disease descriptionAn autosomal recessive disorder characterized by a near complete absence of adipose tissue, extreme insulin resistance, hypertriglyceridemia, hepatic steatosis and early onset of diabetes.
Related information in OMIMFeature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Natural variantiVAR_017328 | 136 | G → R in CGL1; reduced 1-acyl-sn-glycerol-3-phosphate acyltransferase activity. 2 PublicationsCorresponds to variant dbSNP:rs797045222EnsemblClinVar. | 1 | |
Natural variantiVAR_017326 | 140 | Missing in CGL1; reduced 1-acyl-sn-glycerol-3-phosphate acyltransferase activity. 2 Publications | 1 | |
Natural variantiVAR_017327 | 228 | L → P in CGL1; reduced 1-acyl-sn-glycerol-3-phosphate acyltransferase activity. 2 PublicationsCorresponds to variant dbSNP:rs104894100EnsemblClinVar. | 1 | |
Natural variantiVAR_017325 | 239 | A → V in CGL1; 90% of wild-type 1-acyl-sn-glycerol-3-phosphate acyltransferase activity. 2 PublicationsCorresponds to variant dbSNP:rs145975461EnsemblClinVar. | 1 |
Keywords - Diseasei
Congenital generalized lipodystrophy, Diabetes mellitus, Disease mutationOrganism-specific databases
DisGeNETi | 10555 |
GeneReviewsi | AGPAT2 |
MalaCardsi | AGPAT2 |
MIMi | 608594, phenotype |
OpenTargetsi | ENSG00000169692 |
Orphaneti | 528, Berardinelli-Seip congenital lipodystrophy |
PharmGKBi | PA24622 |
Miscellaneous databases
Pharosi | O15120, Tchem |
Chemistry databases
ChEMBLi | CHEMBL4772 |
Polymorphism and mutation databases
BioMutai | AGPAT2 |
PTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Signal peptidei | 1 – 23 | Sequence analysisAdd BLAST | 23 | |
ChainiPRO_0000208192 | 24 – 278 | 1-acyl-sn-glycerol-3-phosphate acyltransferase betaAdd BLAST | 255 |
Proteomic databases
EPDi | O15120 |
jPOSTi | O15120 |
MassIVEi | O15120 |
MaxQBi | O15120 |
PaxDbi | O15120 |
PeptideAtlasi | O15120 |
PRIDEi | O15120 |
ProteomicsDBi | 48457 [O15120-1] 48458 [O15120-2] |
PTM databases
iPTMneti | O15120 |
PhosphoSitePlusi | O15120 |
Expressioni
Tissue specificityi
Expressed predominantly in adipose tissue, pancreas and liver.2 Publications
Gene expression databases
Bgeei | ENSG00000169692, Expressed in subcutaneous adipose tissue and 212 other tissues |
ExpressionAtlasi | O15120, baseline and differential |
Genevisiblei | O15120, HS |
Organism-specific databases
HPAi | ENSG00000169692, Tissue enhanced (adipose tissue, liver) |
Interactioni
Protein-protein interaction databases
BioGRIDi | 115806, 18 interactors |
CORUMi | O15120 |
IntActi | O15120, 17 interactors |
STRINGi | 9606.ENSP00000360761 |
Chemistry databases
BindingDBi | O15120 |
Miscellaneous databases
RNActi | O15120, protein |
Family & Domainsi
Motif
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Motifi | 98 – 103 | HXXXXD motifBy similarity | 6 | |
Motifi | 172 – 175 | EGTR motif1 Publication | 4 |
Domaini
The HXXXXD motif is essential for acyltransferase activity and may constitute the binding site for the phosphate moiety of the glycerol-3-phosphate.By similarity
Sequence similaritiesi
Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family.Curated
Keywords - Domaini
Signal, Transmembrane, Transmembrane helixPhylogenomic databases
eggNOGi | KOG2848, Eukaryota |
GeneTreei | ENSGT00390000008726 |
HOGENOMi | CLU_027938_10_1_1 |
InParanoidi | O15120 |
OMAi | MPRPLCY |
PhylomeDBi | O15120 |
TreeFami | TF314867 |
Family and domain databases
InterProi | View protein in InterPro IPR004552, AGP_acyltrans IPR002123, Plipid/glycerol_acylTrfase |
Pfami | View protein in Pfam PF01553, Acyltransferase, 1 hit |
SMARTi | View protein in SMART SM00563, PlsC, 1 hit |
TIGRFAMsi | TIGR00530, AGP_acyltrn, 1 hit |
s (2)i Sequence
Sequence statusi: Complete.
: The displayed sequence is further processed into a mature form. Sequence processingi
This entry describes 2 produced by isoformsialternative splicing. AlignAdd to basketIsoform 1 (identifier: O15120-1) [UniParc]FASTAAdd to basket
This isoform has been chosen as the sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry. canonicali
10 20 30 40 50
MELWPCLAAA LLLLLLLVQL SRAAEFYAKV ALYCALCFTV SAVASLVCLL
60 70 80 90 100
RHGGRTVENM SIIGWFVRSF KYFYGLRFEV RDPRRLQEAR PCVIVSNHQS
110 120 130 140 150
ILDMMGLMEV LPERCVQIAK RELLFLGPVG LIMYLGGVFF INRQRSSTAM
160 170 180 190 200
TVMADLGERM VRENLKVWIY PEGTRNDNGD LLPFKKGAFY LAVQAQVPIV
210 220 230 240 250
PVVYSSFSSF YNTKKKFFTS GTVTVQVLEA IPTSGLTAAD VPALVDTCHR
260 270
AMRTTFLHIS KTPQENGATA GSGVQPAQ
Experimental Info
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Sequence conflicti | 126 | L → V in AAB64299 (PubMed:9291118).Curated | 1 | |
Sequence conflicti | 200 | V → F in AAH00026 (PubMed:15489334).Curated | 1 |
Natural variant
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Natural variantiVAR_017328 | 136 | G → R in CGL1; reduced 1-acyl-sn-glycerol-3-phosphate acyltransferase activity. 2 PublicationsCorresponds to variant dbSNP:rs797045222EnsemblClinVar. | 1 | |
Natural variantiVAR_017326 | 140 | Missing in CGL1; reduced 1-acyl-sn-glycerol-3-phosphate acyltransferase activity. 2 Publications | 1 | |
Natural variantiVAR_017327 | 228 | L → P in CGL1; reduced 1-acyl-sn-glycerol-3-phosphate acyltransferase activity. 2 PublicationsCorresponds to variant dbSNP:rs104894100EnsemblClinVar. | 1 | |
Natural variantiVAR_017325 | 239 | A → V in CGL1; 90% of wild-type 1-acyl-sn-glycerol-3-phosphate acyltransferase activity. 2 PublicationsCorresponds to variant dbSNP:rs145975461EnsemblClinVar. | 1 |
Alternative sequence
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Alternative sequenceiVSP_005071 | 165 – 196 | Missing in isoform 2. 1 PublicationAdd BLAST | 32 |
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AF000237 mRNA Translation: AAC51649.1 AF011374 mRNA Translation: AAB64299.1 U56418 mRNA Translation: AAB58776.2 AL590226 Genomic DNA No translation available. CH471090 Genomic DNA Translation: EAW88249.1 CH471090 Genomic DNA Translation: EAW88251.1 BC000026 mRNA Translation: AAH00026.1 BC004529 mRNA Translation: AAH04529.1 |
CCDSi | CCDS35181.1 [O15120-2] CCDS7003.1 [O15120-1] |
RefSeqi | NP_001012745.1, NM_001012727.1 [O15120-2] NP_006403.2, NM_006412.3 [O15120-1] |
Genome annotation databases
Ensembli | ENST00000371694; ENSP00000360759; ENSG00000169692 [O15120-2] ENST00000371696; ENSP00000360761; ENSG00000169692 [O15120-1] ENST00000538402; ENSP00000438919; ENSG00000169692 [O15120-1] |
GeneIDi | 10555 |
KEGGi | hsa:10555 |
UCSCi | uc004cii.2, human [O15120-1] |
Keywords - Coding sequence diversityi
Alternative splicingSimilar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AF000237 mRNA Translation: AAC51649.1 AF011374 mRNA Translation: AAB64299.1 U56418 mRNA Translation: AAB58776.2 AL590226 Genomic DNA No translation available. CH471090 Genomic DNA Translation: EAW88249.1 CH471090 Genomic DNA Translation: EAW88251.1 BC000026 mRNA Translation: AAH00026.1 BC004529 mRNA Translation: AAH04529.1 |
CCDSi | CCDS35181.1 [O15120-2] CCDS7003.1 [O15120-1] |
RefSeqi | NP_001012745.1, NM_001012727.1 [O15120-2] NP_006403.2, NM_006412.3 [O15120-1] |
3D structure databases
SMRi | O15120 |
ModBasei | Search... |
Protein-protein interaction databases
BioGRIDi | 115806, 18 interactors |
CORUMi | O15120 |
IntActi | O15120, 17 interactors |
STRINGi | 9606.ENSP00000360761 |
Chemistry databases
BindingDBi | O15120 |
ChEMBLi | CHEMBL4772 |
SwissLipidsi | SLP:000000096 |
PTM databases
iPTMneti | O15120 |
PhosphoSitePlusi | O15120 |
Polymorphism and mutation databases
BioMutai | AGPAT2 |
Proteomic databases
EPDi | O15120 |
jPOSTi | O15120 |
MassIVEi | O15120 |
MaxQBi | O15120 |
PaxDbi | O15120 |
PeptideAtlasi | O15120 |
PRIDEi | O15120 |
ProteomicsDBi | 48457 [O15120-1] 48458 [O15120-2] |
Protocols and materials databases
Antibodypediai | 18762, 169 antibodies |
DNASUi | 10555 |
Genome annotation databases
Ensembli | ENST00000371694; ENSP00000360759; ENSG00000169692 [O15120-2] ENST00000371696; ENSP00000360761; ENSG00000169692 [O15120-1] ENST00000538402; ENSP00000438919; ENSG00000169692 [O15120-1] |
GeneIDi | 10555 |
KEGGi | hsa:10555 |
UCSCi | uc004cii.2, human [O15120-1] |
Organism-specific databases
CTDi | 10555 |
DisGeNETi | 10555 |
EuPathDBi | HostDB:ENSG00000169692.12 |
GeneCardsi | AGPAT2 |
GeneReviewsi | AGPAT2 |
HGNCi | HGNC:325, AGPAT2 |
HPAi | ENSG00000169692, Tissue enhanced (adipose tissue, liver) |
MalaCardsi | AGPAT2 |
MIMi | 603100, gene 608594, phenotype |
neXtProti | NX_O15120 |
OpenTargetsi | ENSG00000169692 |
Orphaneti | 528, Berardinelli-Seip congenital lipodystrophy |
PharmGKBi | PA24622 |
GenAtlasi | Search... |
Phylogenomic databases
eggNOGi | KOG2848, Eukaryota |
GeneTreei | ENSGT00390000008726 |
HOGENOMi | CLU_027938_10_1_1 |
InParanoidi | O15120 |
OMAi | MPRPLCY |
PhylomeDBi | O15120 |
TreeFami | TF314867 |
Enzyme and pathway databases
UniPathwayi | UPA00557;UER00613 |
BioCyci | MetaCyc:HS09990-MONOMER |
BRENDAi | 2.3.1.51, 2681 |
PathwayCommonsi | O15120 |
Reactomei | R-HSA-1483166, Synthesis of PA R-HSA-6798695, Neutrophil degranulation |
Miscellaneous databases
BioGRID-ORCSi | 10555, 28 hits in 839 CRISPR screens |
GeneWikii | AGPAT2 |
GenomeRNAii | 10555 |
Pharosi | O15120, Tchem |
PROi | PR:O15120 |
RNActi | O15120, protein |
SOURCEi | Search... |
Gene expression databases
Bgeei | ENSG00000169692, Expressed in subcutaneous adipose tissue and 212 other tissues |
ExpressionAtlasi | O15120, baseline and differential |
Genevisiblei | O15120, HS |
Family and domain databases
InterProi | View protein in InterPro IPR004552, AGP_acyltrans IPR002123, Plipid/glycerol_acylTrfase |
Pfami | View protein in Pfam PF01553, Acyltransferase, 1 hit |
SMARTi | View protein in SMART SM00563, PlsC, 1 hit |
TIGRFAMsi | TIGR00530, AGP_acyltrn, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | PLCB_HUMAN | |
Accessioni | O15120Primary (citable) accession number: O15120 Secondary accession number(s): O00516 Q9BWR7 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | December 15, 1998 |
Last sequence update: | January 1, 1998 | |
Last modified: | December 2, 2020 | |
This is version 184 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Chordata Protein Annotation Program | |
Disclaimer | Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. |
Miscellaneousi
Keywords - Technical termi
Reference proteomeDocuments
- Human chromosome 9
Human chromosome 9: entries, gene names and cross-references to MIM - Human polymorphisms and disease mutations
Index of human polymorphisms and disease mutations - MIM cross-references
Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot - PATHWAY comments
Index of metabolic and biosynthesis pathways - SIMILARITY comments
Index of protein domains and families - Human entries with polymorphisms or disease mutations
List of human entries with polymorphisms or disease mutations