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UniProtKB - O15090 (ZN536_HUMAN)

Protein

Zinc finger protein 536

Gene

ZNF536

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score:

Annotation score:4 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

May be involved in transcriptional regulation. Recognizes and binds 2 copies of the core DNA sequence 5'-CCCCCA-3'.

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Function’ section specifies the position(s) and type(s) of zinc fingers within the protein.<p><a href='/help/zn_fing' target='_top'>More...</a></p>Zinc fingeri130 – 152C2H2-type 1PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri158 – 180C2H2-type 2PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri274 – 297C2H2-type 3PROSITE-ProRule annotationAdd BLAST24
Zinc fingeri300 – 323C2H2-type 4PROSITE-ProRule annotationAdd BLAST24
Zinc fingeri345 – 367C2H2-type 5PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri373 – 395C2H2-type 6PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri631 – 653C2H2-type 7PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri751 – 773C2H2-type 8PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri779 – 801C2H2-type 9PROSITE-ProRule annotationAdd BLAST23

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

View the complete GO annotation on QuickGO ...

GO - Biological processi

View the complete GO annotation on QuickGO ...

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionDNA-binding
Biological processTranscription, Transcription regulation
LigandMetal-binding, Zinc

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Zinc finger protein 536
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:ZNF536
Synonyms:KIAA0390
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 19

Organism-specific databases

Eukaryotic Pathogen Database Resources

More...EuPathDBi		HostDB:ENSG00000198597.8

Human Gene Nomenclature Database

More...HGNCi		HGNC:29025 ZNF536

Online Mendelian Inheritance in Man (OMIM)

More...MIMi		618037 gene

neXtProt; the human protein knowledge platform

More...neXtProti		NX_O15090

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Nucleus

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

DisGeNET

More...DisGeNETi		9745

Open Targets

More...OpenTargetsi		ENSG00000198597

The Pharmacogenetics and Pharmacogenomics Knowledge Base

More...PharmGKBi		PA134920047

Polymorphism and mutation databases

BioMuta curated single-nucleotide variation and disease association database

More...BioMutai		ZNF536

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00002710411 – 1300Zinc finger protein 536Add BLAST1300

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section specifies the position and type of each modified residue excluding <a href="http://www.uniprot.org/manual/lipid">lipids</a>, <a href="http://www.uniprot.org/manual/carbohyd">glycans</a> and <a href="http://www.uniprot.org/manual/crosslnk">protein cross-links</a>.<p><a href='/help/mod_res' target='_top'>More...</a></p>Modified residuei826PhosphoserineCombined sources1
Modified residuei827PhosphoserineCombined sources1

Keywords - PTMi

Phosphoprotein

Proteomic databases

jPOST - Japan Proteome Standard Repository/Database

More...jPOSTi		O15090

MaxQB - The MaxQuant DataBase

More...MaxQBi		O15090

PaxDb, a database of protein abundance averages across all three domains of life

More...PaxDbi		O15090

PeptideAtlas

More...PeptideAtlasi		O15090

PRoteomics IDEntifications database

More...PRIDEi		O15090

ProteomicsDB human proteome resource

More...ProteomicsDBi		48443

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...iPTMneti		O15090

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...PhosphoSitePlusi		O15090

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...Bgeei		ENSG00000198597 Expressed in 140 organ(s), highest expression level in pigmented layer of retina

CleanEx database of gene expression profiles

More...CleanExi		HS_ZNF536

ExpressionAtlas, Differential and Baseline Expression

More...ExpressionAtlasi		O15090 baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...Genevisiblei		O15090 HS

Organism-specific databases

Human Protein Atlas

More...HPAi		HPA077341

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGrid)

More...BioGridi		115093, 6 interactors

Protein interaction database and analysis system

More...IntActi		O15090, 3 interactors

Molecular INTeraction database

More...MINTi		O15090

STRING: functional protein association networks

More...STRINGi		9606.ENSP00000347730

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

Protein Model Portal of the PSI-Nature Structural Biology Knowledgebase

More...ProteinModelPortali		O15090

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...SMRi		O15090

Database of comparative protein structure models

More...ModBasei		Search...

MobiDB: a database of protein disorder and mobility annotations

More...MobiDBi		Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

<p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the krueppel C2H2-type zinc-finger protein family.Curated

Zinc finger

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Zinc fingeri130 – 152C2H2-type 1PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri158 – 180C2H2-type 2PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri274 – 297C2H2-type 3PROSITE-ProRule annotationAdd BLAST24
Zinc fingeri300 – 323C2H2-type 4PROSITE-ProRule annotationAdd BLAST24
Zinc fingeri345 – 367C2H2-type 5PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri373 – 395C2H2-type 6PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri631 – 653C2H2-type 7PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri751 – 773C2H2-type 8PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri779 – 801C2H2-type 9PROSITE-ProRule annotationAdd BLAST23

Keywords - Domaini

Repeat, Zinc-finger

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...eggNOGi		KOG1721 Eukaryota
COG5048 LUCA

Ensembl GeneTree

More...GeneTreei		ENSGT00940000156397

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...HOGENOMi		HOG000155801

The HOVERGEN Database of Homologous Vertebrate Genes

More...HOVERGENi		HBG080712

InParanoid: Eukaryotic Ortholog Groups

More...InParanoidi		O15090

Identification of Orthologs from Complete Genome Data

More...OMAi		RDKQMKS

Database of Orthologous Groups

More...OrthoDBi		1318335at2759

Database for complete collections of gene phylogenies

More...PhylomeDBi		O15090

TreeFam database of animal gene trees

More...TreeFami		TF332241

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...InterProi		View protein in InterPro
IPR036236 Znf_C2H2_sf
IPR013087 Znf_C2H2_type

Pfam protein domain database

More...Pfami		View protein in Pfam
PF00096 zf-C2H2, 4 hits

Simple Modular Architecture Research Tool; a protein domain database

More...SMARTi		View protein in SMART
SM00355 ZnF_C2H2, 10 hits

Superfamily database of structural and functional annotation

More...SUPFAMi		SSF57667 SSF57667, 5 hits

PROSITE; a protein domain and family database

More...PROSITEi		View protein in PROSITE
PS00028 ZINC_FINGER_C2H2_1, 6 hits
PS50157 ZINC_FINGER_C2H2_2, 8 hits

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>.<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequence (1+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry has 1 described isoform and 3 potential isoforms that are computationally mapped.Show allAlign All

O15090-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MEEASLCLGV SSAEPEAEPH LSGPVLNGQY AMSQKLHQIT SQLSHAFPEL 
        60         70         80         90        100
HPRPNPEEKP PASLEEKAHV PMSGQPMGSQ MALLANQLGR EVDTSLNGRV 
       110        120        130        140        150
DLQQFLNGQN LGIMSQMSDI EDDARKNRKY PCPLCGKRFR FNSILSLHMR 
       160        170        180        190        200
THTGEKPFKC PYCDHRAAQK GNLKIHLRTH KLGNLGKGRG RVREENRLLH 
       210        220        230        240        250
ELEERAILRD KQLKGSLLQP RPDLKPPPHA QQAPLAACTL ALQANHSVPD 
       260        270        280        290        300
VAHPVPSPKP ASVQEDAVAP AAGFRCTFCK GKFKKREELD RHIRILHKPY 
       310        320        330        340        350
KCTLCDFAAS QEEELISHVE KAHITAESAQ GQGPNGGGEQ SANEFRCEVC 
       360        370        380        390        400
GQVFSQAWFL KGHMRKHKDS FEHCCQICGR RFKEPWFLKN HMKVHLNKLS 
       410        420        430        440        450
VKNKSPSDPE VPVPMGGMSQ EAHANLYSRY LSCLQSGFMT PDKAGLSEPS 
       460        470        480        490        500
QLYGKGELPM KEKEALGKLL SPISSMAHGV PEGDKHSLLG CLNLVPPLKS 
       510        520        530        540        550
SCIERLQAAA KAAEMDPVNS YQAWQLMARG MAMEHGFLSK EHPLQRNHED 
       560        570        580        590        600
TLANAGVLFD KEKREYVLVG ADGSKQKMPA DLVHSTKVGS QRDLPSKLDP 
       610        620        630        640        650
LESSRDFLSH GLNQTLEYNL QGPGNMKEKP TECPDCGRVF RTYHQVVVHS 
       660        670        680        690        700
RVHKRDRKGE EDGLHVGLDE RRGSGSDQES QSVSRSTTPG SSNVTEESGV 
       710        720        730        740        750
GGGLSQTGSA QEDSPHPSSP SSSDIGEEAG RSAGVQQPAL LRDRSLGSAM 
       760        770        780        790        800
KDCPYCGKTF RTSHHLKVHL RIHTGEKPYK CPHCDYAGTQ SASLKYHLER 
       810        820        830        840        850
HHRERQNGAG PLSGQPPNQD HKDEMSSKAS LFIRPDILRG AFKGLPGIDF 
       860        870        880        890        900
RGGPASQQWT SGVLSSGDHS GQATGMSSEV PSDALKGTDL PSKSTHFSEI 
       910        920        930        940        950
GRAYQSIVSN GVNFQGSLQA FMDSFVLSSL KKEKDMKDKA LADPPSMKVH 
       960        970        980        990       1000
GVDGGEEKPS GKSSQRKSEK SQYEPLDLSV RPDAASLPGS SVTVQDSIAW 
      1010       1020       1030       1040       1050
HGCLFCAFTT SSMELMALHL QANHLGKAKR KDNTIGVTVN CKDQAREASK 
      1060       1070       1080       1090       1100
MALLPSLQSN KDLGLSNMIS SLDSASEKMA QGQLKETLGE QKSGAWTGHV 
      1110       1120       1130       1140       1150
DPAFCNFPSD FYKQFGVYPG MVGSGASSSC PNKEPDGKAH SEEDVPILIP 
      1160       1170       1180       1190       1200
ETTSKNTTDD LSDIASSEDM DSSKGENNDE EDVETEPEMM TKPLSALSKD 
      1210       1220       1230       1240       1250
SSSDGGDSLQ PTGTSQPVQG LVSPLSQAPE KQWHSQGLLQ AQDPLAGLPK 
      1260       1270       1280       1290       1300
PERGPQSLDK PMNMLSVLRA YSSDGLAAFN GLASSTANSG CIKRPDLCGK
Length:1,300
Mass (Da):141,417
Last modified:January 9, 2007 - v3
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i858B5B7047653664
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There are 3 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
K7EKT4K7EKT4_HUMAN
Zinc finger protein 536
ZNF536
949Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
K7EQN6K7EQN6_HUMAN
Zinc finger protein 536
ZNF536
137Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
K7EJP8K7EJP8_HUMAN
Zinc finger protein 536
ZNF536
138Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

<p>This subsection of the ‘Sequence’ section reports difference(s) between the protein sequence shown in the UniProtKB entry and other available protein sequences derived from the same gene.<p><a href='/help/sequence_caution' target='_top'>More...</a></p>Sequence cautioni

The sequence BAA20844 differs from that shown. Reason: Erroneous initiation.Curated

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...EMBLi

GenBank nucleotide sequence database

More...GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...DDBJi
Links Updated
AB002388 mRNA Translation: BAA20844.2 Different initiation.
BC132720 mRNA Translation: AAI32721.1
BC132722 mRNA Translation: AAI32723.1
BC146757 mRNA Translation: AAI46758.1

The Consensus CDS (CCDS) project

More...CCDSi		CCDS32984.1

NCBI Reference Sequences

More...RefSeqi		NP_055532.1, NM_014717.2
XP_016883031.1, XM_017027542.1

UniGene gene-oriented nucleotide sequence clusters

More...UniGenei		Hs.378901

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...Ensembli		ENST00000355537; ENSP00000347730; ENSG00000198597

Database of genes from NCBI RefSeq genomes

More...GeneIDi		9745

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...KEGGi		hsa:9745

UCSC genome browser

More...UCSCi		uc002nsu.2 human

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AB002388 mRNA Translation: BAA20844.2 Different initiation.
BC132720 mRNA Translation: AAI32721.1
BC132722 mRNA Translation: AAI32723.1
BC146757 mRNA Translation: AAI46758.1
CCDSiCCDS32984.1
RefSeqiNP_055532.1, NM_014717.2
XP_016883031.1, XM_017027542.1
UniGeneiHs.378901

3D structure databases

ProteinModelPortaliO15090
SMRiO15090
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi115093, 6 interactors
IntActiO15090, 3 interactors
MINTiO15090
STRINGi9606.ENSP00000347730

PTM databases

iPTMnetiO15090
PhosphoSitePlusiO15090

Polymorphism and mutation databases

BioMutaiZNF536

Proteomic databases

jPOSTiO15090
MaxQBiO15090
PaxDbiO15090
PeptideAtlasiO15090
PRIDEiO15090
ProteomicsDBi48443

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000355537; ENSP00000347730; ENSG00000198597
GeneIDi9745
KEGGihsa:9745
UCSCiuc002nsu.2 human

Organism-specific databases

Comparative Toxicogenomics Database

More...CTDi		9745
DisGeNETi9745
EuPathDBiHostDB:ENSG00000198597.8

GeneCards: human genes, protein and diseases

More...GeneCardsi		ZNF536
HGNCiHGNC:29025 ZNF536
HPAiHPA077341
MIMi618037 gene
neXtProtiNX_O15090
OpenTargetsiENSG00000198597
PharmGKBiPA134920047

Human Unidentified Gene-Encoded large proteins database

More...HUGEi		Search...

GenAtlas: human gene database

More...GenAtlasi		Search...

Phylogenomic databases

eggNOGiKOG1721 Eukaryota
COG5048 LUCA
GeneTreeiENSGT00940000156397
HOGENOMiHOG000155801
HOVERGENiHBG080712
InParanoidiO15090
OMAiRDKQMKS
OrthoDBi1318335at2759
PhylomeDBiO15090
TreeFamiTF332241

Miscellaneous databases

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

More...ChiTaRSi		ZNF536 human

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

More...GenomeRNAii		9745

Protein Ontology

More...PROi		PR:O15090

The Stanford Online Universal Resource for Clones and ESTs

More...SOURCEi		Search...

Gene expression databases

BgeeiENSG00000198597 Expressed in 140 organ(s), highest expression level in pigmented layer of retina
CleanExiHS_ZNF536
ExpressionAtlasiO15090 baseline and differential
GenevisibleiO15090 HS

Family and domain databases

InterProiView protein in InterPro
IPR036236 Znf_C2H2_sf
IPR013087 Znf_C2H2_type
PfamiView protein in Pfam
PF00096 zf-C2H2, 4 hits
SMARTiView protein in SMART
SM00355 ZnF_C2H2, 10 hits
SUPFAMiSSF57667 SSF57667, 5 hits
PROSITEiView protein in PROSITE
PS00028 ZINC_FINGER_C2H2_1, 6 hits
PS50157 ZINC_FINGER_C2H2_2, 8 hits

ProtoNet; Automatic hierarchical classification of proteins

More...ProtoNeti		Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiZN536_HUMAN
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: O15090
Secondary accession number(s): A2RU18
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: January 9, 2007
Last sequence update: January 9, 2007
Last modified: January 16, 2019
This is version 148 of the entry and version 3 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
  2. MIM cross-references
    Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
  3. Human chromosome 19
    Human chromosome 19: entries, gene names and cross-references to MIM
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