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UniProtKB - O15062 (ZBTB5_HUMAN)

Entry version 169 (23 Feb 2022)
Sequence version 1 (01 Jan 1998)
Previous versions | rss
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Protein

Zinc finger and BTB domain-containing protein 5

Gene

ZBTB5

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

May be involved in transcriptional regulation.

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/function%5Fsection">Function</a> section specifies the position(s) and type(s) of zinc fingers within the protein.<p><a href='/help/zn_fing' target='_top'>More...</a></p>Zinc fingeri613 – 635C2H2-type 1PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri641 – 664C2H2-type 2; atypicalPROSITE-ProRule annotationAdd BLAST24

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

Complete GO annotation on QuickGO ...

GO - Biological processi

Complete GO annotation on QuickGO ...

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionDNA-binding
Biological processTranscription, Transcription regulation
LigandMetal-binding, Zinc

Enzyme and pathway databases

Pathway Commons web resource for biological pathway data

More...PathwayCommonsi		O15062

SignaLink: a signaling pathway resource with multi-layered regulatory networks

More...SignaLinki		O15062

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Zinc finger and BTB domain-containing protein 5
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:ZBTB5
Synonyms:KIAA0354
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 9

Organism-specific databases

Human Gene Nomenclature Database

More...HGNCi		HGNC:23836, ZBTB5

Online Mendelian Inheritance in Man (OMIM)

More...MIMi		616590, gene

neXtProt; the human protein knowledge platform

More...neXtProti		NX_O15062

Eukaryotic Pathogen, Vector and Host Database Resources

More...VEuPathDBi		HostDB:ENSG00000168795

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Keywords - Cellular componenti

Nucleus

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

DisGeNET

More...DisGeNETi		9925

Open Targets

More...OpenTargetsi		ENSG00000168795

The Pharmacogenetics and Pharmacogenomics Knowledge Base

More...PharmGKBi		PA134969268

Miscellaneous databases

Pharos NIH Druggable Genome Knowledgebase

More...Pharosi		O15062, Tbio

Genetic variation databases

BioMuta curated single-nucleotide variation and disease association database

More...BioMutai		ZBTB5

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00000477131 – 677Zinc finger and BTB domain-containing protein 5Add BLAST677

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section specifies the position and type of each modified residue excluding <a href="http://www.uniprot.org/manual/lipid">lipids</a>, <a href="http://www.uniprot.org/manual/carbohyd">glycans</a> and <a href="http://www.uniprot.org/manual/crosslnk">protein cross-links</a>.<p><a href='/help/mod_res' target='_top'>More...</a></p>Modified residuei234PhosphoserineCombined sources1
<p>This subsection of the <a href="http://www.uniprot.org/help/ptm%5Fprocessing%5Fsection">PTM / Processing</a> section describes <strong>covalent linkages</strong> of various types formed <strong>between two proteins (interchain cross-links)</strong> or <strong>between two parts of the same protein (intrachain cross-links)</strong>, except the disulfide bonds that are annotated in the <a href="http://www.uniprot.org/manual/disulfid">'Disulfide bond'</a> subsection.<p><a href='/help/crosslnk' target='_top'>More...</a></p>Cross-linki239Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)Combined sources
Cross-linki322Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)Combined sources
Cross-linki330Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)Combined sources
Modified residuei371PhosphoserineCombined sources1
Cross-linki404Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)Combined sources
Cross-linki415Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)Combined sources
Cross-linki541Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)Combined sources
Cross-linki594Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)Combined sources
Cross-linki597Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)Combined sources
Cross-linki645Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)Combined sources
Cross-linki658Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)Combined sources

Keywords - PTMi

Isopeptide bond, Phosphoprotein, Ubl conjugation

Proteomic databases

Encyclopedia of Proteome Dynamics

More...EPDi		O15062

jPOST - Japan Proteome Standard Repository/Database

More...jPOSTi		O15062

MassIVE - Mass Spectrometry Interactive Virtual Environment

More...MassIVEi		O15062

PaxDb, a database of protein abundance averages across all three domains of life

More...PaxDbi		O15062

PeptideAtlas

More...PeptideAtlasi		O15062

PRoteomics IDEntifications database

More...PRIDEi		O15062

ProteomicsDB: a multi-organism proteome resource

More...ProteomicsDBi		48414

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...iPTMneti		O15062

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...PhosphoSitePlusi		O15062

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...Bgeei		ENSG00000168795, Expressed in esophagus squamous epithelium and 224 other tissues

ExpressionAtlas, Differential and Baseline Expression

More...ExpressionAtlasi		O15062, baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...Genevisiblei		O15062, HS

Organism-specific databases

Human Protein Atlas

More...HPAi		ENSG00000168795, Low tissue specificity

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the '<a href="http://www.uniprot.org/help/interaction%5Fsection">Interaction</a>' section provides information about binary protein-protein interactions. The data presented in this section are a quality-filtered subset of binary interactions automatically derived from the <a href="https://www.ebi.ac.uk/intact/">IntAct database</a>. It is updated at every <a href="http://www.uniprot.org/help/synchronization">UniProt release</a>.<p><a href='/help/binary_interactions' target='_top'>More...</a></p>Binary interactionsi

Hide details

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGRID)

More...BioGRIDi		115253, 40 interactors

Database of interacting proteins

More...DIPi		DIP-41566N

Protein interaction database and analysis system

More...IntActi		O15062, 25 interactors

Molecular INTeraction database

More...MINTi		O15062

STRING: functional protein association networks

More...STRINGi		9606.ENSP00000307604

Miscellaneous databases

RNAct, Protein-RNA interaction predictions for model organisms.

More...RNActi		O15062, protein

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...SMRi		O15062

Database of comparative protein structure models

More...ModBasei		Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family%5Fand%5Fdomains%5Fsection">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini24 – 93BTBPROSITE-ProRule annotationAdd BLAST70

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni158 – 252DisorderedSequence analysisAdd BLAST95
Regioni287 – 312DisorderedSequence analysisAdd BLAST26
Regioni331 – 387DisorderedSequence analysisAdd BLAST57
Regioni447 – 474DisorderedSequence analysisAdd BLAST28
Regioni552 – 585DisorderedSequence analysisAdd BLAST34

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes the position of regions of compositional bias within the protein and the particular type of amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi158 – 181Polar residuesSequence analysisAdd BLAST24
Compositional biasi191 – 209Basic and acidic residuesSequence analysisAdd BLAST19
Compositional biasi287 – 308Polar residuesSequence analysisAdd BLAST22
Compositional biasi337 – 354Polar residuesSequence analysisAdd BLAST18
Compositional biasi552 – 584Polar residuesSequence analysisAdd BLAST33

Zinc finger

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Zinc fingeri613 – 635C2H2-type 1PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri641 – 664C2H2-type 2; atypicalPROSITE-ProRule annotationAdd BLAST24

Keywords - Domaini

Repeat, Zinc-finger

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...eggNOGi		KOG1721, Eukaryota

Ensembl GeneTree

More...GeneTreei		ENSGT00940000160246

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...HOGENOMi		CLU_407055_0_0_1

InParanoid: Eukaryotic Ortholog Groups

More...InParanoidi		O15062

Identification of Orthologs from Complete Genome Data

More...OMAi		QLMMNAA

Database of Orthologous Groups

More...OrthoDBi		339939at2759

Database for complete collections of gene phylogenies

More...PhylomeDBi		O15062

TreeFam database of animal gene trees

More...TreeFami		TF330979

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

More...Gene3Di		3.30.710.10, 1 hit

Integrated resource of protein families, domains and functional sites

More...InterProi		View protein in InterPro
IPR000210, BTB/POZ_dom
IPR011333, SKP1/BTB/POZ_sf
IPR036236, Znf_C2H2_sf
IPR013087, Znf_C2H2_type

Pfam protein domain database

More...Pfami		View protein in Pfam
PF00651, BTB, 1 hit

Simple Modular Architecture Research Tool; a protein domain database

More...SMARTi		View protein in SMART
SM00225, BTB, 1 hit
SM00355, ZnF_C2H2, 2 hits

Superfamily database of structural and functional annotation

More...SUPFAMi		SSF54695, SSF54695, 1 hit
SSF57667, SSF57667, 1 hit

PROSITE; a protein domain and family database

More...PROSITEi		View protein in PROSITE
PS50097, BTB, 1 hit
PS00028, ZINC_FINGER_C2H2_1, 1 hit
PS50157, ZINC_FINGER_C2H2_2, 2 hits

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

O15062-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MDFPGHFEQI FQQLNYQRLH GQLCDCVIVV GNRHFKAHRS VLAACSTHFR 
        60         70         80         90        100
ALFSVAEGDQ TMNMIQLDSE VVTAEAFAAL IDMMYTSTLM LGESNVMDVL 
       110        120        130        140        150
LAASHLHLNS VVKACKHYLT TRTLPMSPPS ERVQEQSARM QRSFMLQQLG 
       160        170        180        190        200
LSIVSSALNS SQNGEEQPAP MSSSMRSNLD QRTPFPMRRL HKRKQSAEER 
       210        220        230        240        250
ARQRLRPSID ESAISDVTPE NGPSGVHSRE EFFSPDSLKI VDNPKADGMT 
       260        270        280        290        300
DNQEDSAIMF DQSFGTQEDA QVPSQSDNSA GNMAQLSMAS RATQVETSFD 
       310        320        330        340        350
QEAAPEKSSF QCENPEVGLG EKEHMRVVVK SEPLSSPEPQ DEVSDVTSQA 
       360        370        380        390        400
EGSESVEVEG VVVSAEKIDL SPESSDRSFS DPQSSTDRVG DIHILEVTNN 
       410        420        430        440        450
LEHKSTFSIS NFLNKSRGNN FTANQNNDDN IPNTTSDCRL ESEAPYLLSP 
       460        470        480        490        500
EAGPAGGPSS APGSHVENPF SEPADSHFVR PMQEVMGLPC VQTSGYQGGE 
       510        520        530        540        550
QFGMDFSRSG LGLHSSFSRV MIGSPRGGAS NFPYYRRIAP KMPVVTSVRS 
       560        570        580        590        600
SQIPENSTSS QLMMNGATSS FENGHPSQPG PPQLTRASAD VLSKCKKALS 
       610        620        630        640        650
EHNVLVVEGA RKYACKICCK TFLTLTDCKK HIRVHTGEKP YACLKCGKRF 
       660        670 
SQSSHLYKHS KTTCLRWQSS NLPSTLL
Length:677
Mass (Da):74,278
Last modified:January 1, 1998 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i0F17A0AEE3FD827B
GO

<p>This subsection of the 'Sequence' section reports difference(s) between the protein sequence shown in the UniProtKB entry and other available protein sequences derived from the same gene.<p><a href='/help/sequence_caution' target='_top'>More...</a></p>Sequence cautioni

The sequence BAA20811 differs from that shown. Reason: Erroneous initiation.Curated

Natural variant

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section describes natural variant(s) of the protein sequence.<p><a href='/help/variant' target='_top'>More...</a></p>Natural variantiVAR_052915300D → G. Corresponds to variant dbSNP:rs17502738Ensembl.1

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...EMBLi

GenBank nucleotide sequence database

More...GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...DDBJi
Links Updated
AB002352 mRNA Translation: BAA20811.2 Different initiation.
BC010007 mRNA Translation: AAH10007.1

The Consensus CDS (CCDS) project

More...CCDSi		CCDS6610.1

NCBI Reference Sequences

More...RefSeqi		NP_055687.1, NM_014872.2
XP_005251691.1, XM_005251634.1

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...Ensembli		ENST00000307750; ENSP00000307604; ENSG00000168795

Database of genes from NCBI RefSeq genomes

More...GeneIDi		9925

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...KEGGi		hsa:9925

Matched Annotation from NCBI and EMBL-EBI (MANE) - Phase one

More...MANE-Selecti		ENST00000307750.5; ENSP00000307604.4; NM_014872.3; NP_055687.1

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AB002352 mRNA Translation: BAA20811.2 Different initiation.
BC010007 mRNA Translation: AAH10007.1
CCDSiCCDS6610.1
RefSeqiNP_055687.1, NM_014872.2
XP_005251691.1, XM_005251634.1

3D structure databases

SMRiO15062
ModBaseiSearch...

Protein-protein interaction databases

BioGRIDi115253, 40 interactors
DIPiDIP-41566N
IntActiO15062, 25 interactors
MINTiO15062
STRINGi9606.ENSP00000307604

PTM databases

iPTMnetiO15062
PhosphoSitePlusiO15062

Genetic variation databases

BioMutaiZBTB5

Proteomic databases

EPDiO15062
jPOSTiO15062
MassIVEiO15062
PaxDbiO15062
PeptideAtlasiO15062
PRIDEiO15062
ProteomicsDBi48414

Protocols and materials databases

Antibodypedia a portal for validated antibodies

More...Antibodypediai		26273, 141 antibodies from 24 providers

The DNASU plasmid repository

More...DNASUi		9925

Genome annotation databases

EnsembliENST00000307750; ENSP00000307604; ENSG00000168795
GeneIDi9925
KEGGihsa:9925
MANE-SelectiENST00000307750.5; ENSP00000307604.4; NM_014872.3; NP_055687.1

Organism-specific databases

Comparative Toxicogenomics Database

More...CTDi		9925
DisGeNETi9925

GeneCards: human genes, protein and diseases

More...GeneCardsi		ZBTB5
HGNCiHGNC:23836, ZBTB5
HPAiENSG00000168795, Low tissue specificity
MIMi616590, gene
neXtProtiNX_O15062
OpenTargetsiENSG00000168795
PharmGKBiPA134969268
VEuPathDBiHostDB:ENSG00000168795

Human Unidentified Gene-Encoded large proteins database

More...HUGEi		Search...

GenAtlas: human gene database

More...GenAtlasi		Search...

Phylogenomic databases

eggNOGiKOG1721, Eukaryota
GeneTreeiENSGT00940000160246
HOGENOMiCLU_407055_0_0_1
InParanoidiO15062
OMAiQLMMNAA
OrthoDBi339939at2759
PhylomeDBiO15062
TreeFamiTF330979

Enzyme and pathway databases

PathwayCommonsiO15062
SignaLinkiO15062

Miscellaneous databases

BioGRID ORCS database of CRISPR phenotype screens

More...BioGRID-ORCSi		9925, 7 hits in 1087 CRISPR screens

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

More...ChiTaRSi		ZBTB5, human

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

More...GenomeRNAii		9925
PharosiO15062, Tbio

Protein Ontology

More...PROi		PR:O15062
RNActiO15062, protein

The Stanford Online Universal Resource for Clones and ESTs

More...SOURCEi		Search...

Gene expression databases

BgeeiENSG00000168795, Expressed in esophagus squamous epithelium and 224 other tissues
ExpressionAtlasiO15062, baseline and differential
GenevisibleiO15062, HS

Family and domain databases

Gene3Di3.30.710.10, 1 hit
InterProiView protein in InterPro
IPR000210, BTB/POZ_dom
IPR011333, SKP1/BTB/POZ_sf
IPR036236, Znf_C2H2_sf
IPR013087, Znf_C2H2_type
PfamiView protein in Pfam
PF00651, BTB, 1 hit
SMARTiView protein in SMART
SM00225, BTB, 1 hit
SM00355, ZnF_C2H2, 2 hits
SUPFAMiSSF54695, SSF54695, 1 hit
SSF57667, SSF57667, 1 hit
PROSITEiView protein in PROSITE
PS50097, BTB, 1 hit
PS00028, ZINC_FINGER_C2H2_1, 1 hit
PS50157, ZINC_FINGER_C2H2_2, 2 hits

MobiDB: a database of protein disorder and mobility annotations

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<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiZBTB5_HUMAN
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: O15062
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: April 26, 2004
Last sequence update: January 1, 1998
Last modified: February 23, 2022
This is version 169 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteome

Documents

  1. Human chromosome 9
    Human chromosome 9: entries, gene names and cross-references to MIM
  2. Human entries with genetic variants
    List of human entries with genetic variants
  3. Human variants curated from literature reports
    Index of human variants curated from literature reports
  4. MIM cross-references
    Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
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