UniProtKB - O15031 (PLXB2_HUMAN)
Plexin-B2
PLXNB2
Functioni
Cell surface receptor for SEMA4C, SEMA4D and SEMA4G that plays an important role in cell-cell signaling (By similarity).
Plays a role in glutamatergic synapse development and is required for SEMA4A-mediated excitatory synapse development (By similarity).
Binding to class 4 semaphorins promotes downstream activation of RHOA and phosphorylation of ERBB2 at 'Tyr-1248' (By similarity).
Required for normal differentiation and migration of neuronal cells during brain corticogenesis and for normal embryonic brain development (By similarity).
Regulates the migration of cerebellar granule cells in the developing brain (By similarity).
Plays a role in RHOA activation and subsequent changes of the actin cytoskeleton (PubMed:12183458).
Plays a role in axon guidance, invasive growth and cell migration (PubMed:15184888).
May modulate the activity of RAC1 and CDC42 (By similarity).
By similarity2 PublicationsGO - Molecular functioni
- semaphorin receptor activity Source: UniProtKB
GO - Biological processi
- brain development Source: UniProtKB
- excitatory synapse assembly Source: UniProtKB
- homophilic cell adhesion via plasma membrane adhesion molecules Source: ParkinsonsUK-UCL
- negative regulation of cell adhesion Source: GO_Central
- neural tube closure Source: UniProtKB
- neuroblast proliferation Source: UniProtKB
- positive regulation of axonogenesis Source: GO_Central
- positive regulation of neuron projection development Source: ParkinsonsUK-UCL
- positive regulation of translation Source: CACAO
- regulation of cell migration Source: GO_Central
- regulation of cell shape Source: UniProtKB
- regulation of GTPase activity Source: UniProtKB
- regulation of neuron migration Source: UniProtKB
- regulation of protein phosphorylation Source: UniProtKB
- semaphorin-plexin signaling pathway Source: UniProtKB
- semaphorin-plexin signaling pathway involved in axon guidance Source: GO_Central
Keywordsi
Molecular function | Developmental protein, Receptor |
Enzyme and pathway databases
PathwayCommonsi | O15031 |
SignaLinki | O15031 |
Names & Taxonomyi
Protein namesi | Recommended name: Plexin-B2Alternative name(s): MM1 |
Gene namesi | Name:PLXNB2 Synonyms:KIAA0315 |
Organismi | Homo sapiens (Human) |
Taxonomic identifieri | 9606 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo |
Proteomesi |
|
Organism-specific databases
HGNCi | HGNC:9104, PLXNB2 |
MIMi | 604293, gene |
neXtProti | NX_O15031 |
VEuPathDBi | HostDB:ENSG00000196576 |
Subcellular locationi
Plasma membrane
- Cell membrane 1 Publication; Single-pass type I membrane protein Sequence analysis
Extracellular region or secreted
- extracellular exosome Source: UniProtKB
Plasma Membrane
- integral component of plasma membrane Source: UniProtKB
Other locations
- cell surface Source: UniProtKB
- semaphorin receptor complex Source: GO_Central
Topology
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Topological domaini | 20 – 1197 | ExtracellularSequence analysisAdd BLAST | 1178 | |
Transmembranei | 1198 – 1218 | HelicalSequence analysisAdd BLAST | 21 | |
Topological domaini | 1219 – 1838 | CytoplasmicSequence analysisAdd BLAST | 620 |
Keywords - Cellular componenti
Cell membrane, MembranePathology & Biotechi
Mutagenesis
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Mutagenesisi | 1161 – 1164 | RQKR → AQKA: Abolishes cleavage by proprotein convertases. 1 Publication | 4 |
Organism-specific databases
DisGeNETi | 23654 |
OpenTargetsi | ENSG00000196576 |
PharmGKBi | PA33430 |
Miscellaneous databases
Pharosi | O15031, Tbio |
Genetic variation databases
BioMutai | PLXNB2 |
PTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Signal peptidei | 1 – 19 | Sequence analysisAdd BLAST | 19 | |
ChainiPRO_0000024673 | 20 – 1838 | Plexin-B2Add BLAST | 1819 |
Amino acid modifications
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Disulfide bondi | 78 ↔ 87 | PROSITE-ProRule annotation | ||
Disulfide bondi | 112 ↔ 120 | PROSITE-ProRule annotation | ||
Glycosylationi | 127 | N-linked (GlcNAc...) asparagine2 Publications | 1 | |
Glycosylationi | 242 | N-linked (GlcNAc...) asparagineSequence analysis | 1 | |
Disulfide bondi | 250 ↔ 364 | PROSITE-ProRule annotation | ||
Disulfide bondi | 266 ↔ 312 | PROSITE-ProRule annotation | ||
Disulfide bondi | 330 ↔ 351 | PROSITE-ProRule annotation | ||
Glycosylationi | 391 | N-linked (GlcNAc...) asparagineSequence analysis | 1 | |
Glycosylationi | 402 | N-linked (GlcNAc...) asparagineSequence analysis | 1 | |
Disulfide bondi | 469 ↔ 486 | PROSITE-ProRule annotation | ||
Disulfide bondi | 475 ↔ 518 | PROSITE-ProRule annotation | ||
Disulfide bondi | 478 ↔ 495 | PROSITE-ProRule annotation | ||
Disulfide bondi | 489 ↔ 501 | PROSITE-ProRule annotation | ||
Glycosylationi | 528 | N-linked (GlcNAc...) asparagineSequence analysis | 1 | |
Disulfide bondi | 555 ↔ 574 | PROSITE-ProRule annotation | ||
Glycosylationi | 733 | N-linked (GlcNAc...) asparagine1 Publication | 1 | |
Glycosylationi | 759 | N-linked (GlcNAc...) asparagineSequence analysis | 1 | |
Glycosylationi | 795 | N-linked (GlcNAc...) asparagineSequence analysis | 1 | |
Glycosylationi | 844 | N-linked (GlcNAc...) asparagineSequence analysis | 1 | |
Glycosylationi | 1002 | N-linked (GlcNAc...) asparagineSequence analysis | 1 | |
Glycosylationi | 1049 | N-linked (GlcNAc...) asparagineSequence analysis | 1 | |
Glycosylationi | 1068 | N-linked (GlcNAc...) asparagineSequence analysis | 1 | |
Glycosylationi | 1099 | N-linked (GlcNAc...) asparagineSequence analysis | 1 | |
Modified residuei | 1236 | PhosphoserineBy similarity | 1 | |
Modified residuei | 1244 | PhosphoserineBy similarity | 1 | |
Modified residuei | 1570 | PhosphoserineBy similarity | 1 |
Sites
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Sitei | 1164 – 1165 | Cleavage; by proprotein convertases | 2 |
Keywords - PTMi
Disulfide bond, Glycoprotein, PhosphoproteinProteomic databases
CPTACi | CPTAC-1504 CPTAC-2603 |
EPDi | O15031 |
jPOSTi | O15031 |
MassIVEi | O15031 |
MaxQBi | O15031 |
PaxDbi | O15031 |
PeptideAtlasi | O15031 |
PRIDEi | O15031 |
ProteomicsDBi | 48388 |
PTM databases
GlyConnecti | 1613, 57 N-Linked glycans (11 sites) |
GlyGeni | O15031, 16 sites, 56 N-linked glycans (11 sites), 1 O-linked glycan (1 site) |
iPTMneti | O15031 |
PhosphoSitePlusi | O15031 |
SwissPalmi | O15031 |
Expressioni
Gene expression databases
Bgeei | ENSG00000196576, Expressed in right uterine tube and 229 other tissues |
ExpressionAtlasi | O15031, baseline and differential |
Genevisiblei | O15031, HS |
Organism-specific databases
HPAi | ENSG00000196576, Low tissue specificity |
Interactioni
Subunit structurei
Binary interactionsi
O15031
With | #Exp. | IntAct |
---|---|---|
MET [P08581] | 2 | EBI-722004,EBI-1039152 |
MST1R [Q04912] | 2 | EBI-722004,EBI-2637518 |
RND1 [Q92730] | 2 | EBI-722004,EBI-448618 |
RND2 [P52198] | 2 | EBI-722004,EBI-1111436 |
RND3 [P61587] | 2 | EBI-722004,EBI-1111534 |
Protein-protein interaction databases
BioGRIDi | 117178, 199 interactors |
IntActi | O15031, 44 interactors |
MINTi | O15031 |
STRINGi | 9606.ENSP00000409171 |
Miscellaneous databases
RNActi | O15031, protein |
Structurei
Secondary structure
3D structure databases
AlphaFoldDBi | O15031 |
SMRi | O15031 |
ModBasei | Search... |
PDBe-KBi | Search... |
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 20 – 466 | SemaPROSITE-ProRule annotationAdd BLAST | 447 | |
Domaini | 803 – 893 | IPT/TIG 1Add BLAST | 91 | |
Domaini | 895 – 980 | IPT/TIG 2Add BLAST | 86 | |
Domaini | 983 – 1092 | IPT/TIG 3Add BLAST | 110 |
Sequence similaritiesi
Keywords - Domaini
Repeat, Signal, Transmembrane, Transmembrane helixPhylogenomic databases
eggNOGi | KOG3610, Eukaryota |
GeneTreei | ENSGT01020000230394 |
HOGENOMi | CLU_001436_1_0_1 |
InParanoidi | O15031 |
OMAi | CTPPIDE |
OrthoDBi | 90434at2759 |
PhylomeDBi | O15031 |
TreeFami | TF312962 |
Family and domain databases
Gene3Di | 1.10.506.10, 1 hit 2.130.10.10, 1 hit 2.60.40.10, 3 hits |
InterProi | View protein in InterPro IPR013783, Ig-like_fold IPR014756, Ig_E-set IPR002909, IPT_dom IPR031148, Plexin IPR013548, Plexin_cytoplasmic_RasGAP_dom IPR002165, Plexin_repeat IPR016201, PSI IPR008936, Rho_GTPase_activation_prot IPR001627, Semap_dom IPR036352, Semap_dom_sf IPR041019, TIG1_plexin IPR015943, WD40/YVTN_repeat-like_dom_sf |
PANTHERi | PTHR22625, PTHR22625, 1 hit |
Pfami | View protein in Pfam PF08337, Plexin_cytopl, 1 hit PF01437, PSI, 1 hit PF01403, Sema, 1 hit PF01833, TIG, 3 hits PF17960, TIG_plexin, 1 hit |
SMARTi | View protein in SMART SM00429, IPT, 3 hits SM00423, PSI, 3 hits SM00630, Sema, 1 hit |
SUPFAMi | SSF101912, SSF101912, 1 hit SSF48350, SSF48350, 1 hit SSF81296, SSF81296, 3 hits |
PROSITEi | View protein in PROSITE PS51004, SEMA, 1 hit |
(1+)i Sequence
Sequence statusi: Complete.
: The displayed sequence is further processed into a mature form. Sequence processingi
This entry has 1 described isoform and 5 potential isoforms that are computationally mapped.Show allAlign All
10 20 30 40 50
MALQLWALTL LGLLGAGASL RPRKLDFFRS EKELNHLAVD EASGVVYLGA
60 70 80 90 100
VNALYQLDAK LQLEQQVATG PALDNKKCTP PIEASQCHEA EMTDNVNQLL
110 120 130 140 150
LLDPPRKRLV ECGSLFKGIC ALRALSNISL RLFYEDGSGE KSFVASNDEG
160 170 180 190 200
VATVGLVSST GPGGDRVLFV GKGNGPHDNG IIVSTRLLDR TDSREAFEAY
210 220 230 240 250
TDHATYKAGY LSTNTQQFVA AFEDGPYVFF VFNQQDKHPA RNRTLLARMC
260 270 280 290 300
REDPNYYSYL EMDLQCRDPD IHAAAFGTCL AASVAAPGSG RVLYAVFSRD
310 320 330 340 350
SRSSGGPGAG LCLFPLDKVH AKMEANRNAC YTGTREARDI FYKPFHGDIQ
360 370 380 390 400
CGGHAPGSSK SFPCGSEHLP YPLGSRDGLR GTAVLQRGGL NLTAVTVAAE
410 420 430 440 450
NNHTVAFLGT SDGRILKVYL TPDGTSSEYD SILVEINKRV KRDLVLSGDL
460 470 480 490 500
GSLYAMTQDK VFRLPVQECL SYPTCTQCRD SQDPYCGWCV VEGRCTRKAE
510 520 530 540 550
CPRAEEASHW LWSRSKSCVA VTSAQPQNMS RRAQGEVQLT VSPLPALSEE
560 570 580 590 600
DELLCLFGES PPHPARVEGE AVICNSPSSI PVTPPGQDHV AVTIQLLLRR
610 620 630 640 650
GNIFLTSYQY PFYDCRQAMS LEENLPCISC VSNRWTCQWD LRYHECREAS
660 670 680 690 700
PNPEDGIVRA HMEDSCPQFL GPSPLVIPMN HETDVNFQGK NLDTVKGSSL
710 720 730 740 750
HVGSDLLKFM EPVTMQESGT FAFRTPKLSH DANETLPLHL YVKSYGKNID
760 770 780 790 800
SKLHVTLYNC SFGRSDCSLC RAANPDYRCA WCGGQSRCVY EALCNTTSEC
810 820 830 840 850
PPPVITRIQP ETGPLGGGIR ITILGSNLGV QAGDIQRISV AGRNCSFQPE
860 870 880 890 900
RYSVSTRIVC VIEAAETPFT GGVEVDVFGK LGRSPPNVQF TFQQPKPLSV
910 920 930 940 950
EPQQGPQAGG TTLTIHGTHL DTGSQEDVRV TLNGVPCKVT KFGAQLQCVT
960 970 980 990 1000
GPQATRGQML LEVSYGGSPV PNPGIFFTYR ENPVLRAFEP LRSFASGGRS
1010 1020 1030 1040 1050
INVTGQGFSL IQRFAMVVIA EPLQSWQPPR EAESLQPMTV VGTDYVFHND
1060 1070 1080 1090 1100
TKVVFLSPAV PEEPEAYNLT VLIEMDGHRA LLRTEAGAFE YVPDPTFENF
1110 1120 1130 1140 1150
TGGVKKQVNK LIHARGTNLN KAMTLQEAEA FVGAERCTMK TLTETDLYCE
1160 1170 1180 1190 1200
PPEVQPPPKR RQKRDTTHNL PEFIVKFGSR EWVLGRVEYD TRVSDVPLSL
1210 1220 1230 1240 1250
ILPLVIVPMV VVIAVSVYCY WRKSQQAERE YEKIKSQLEG LEESVRDRCK
1260 1270 1280 1290 1300
KEFTDLMIEM EDQTNDVHEA GIPVLDYKTY TDRVFFLPSK DGDKDVMITG
1310 1320 1330 1340 1350
KLDIPEPRRP VVEQALYQFS NLLNSKSFLI NFIHTLENQR EFSARAKVYF
1360 1370 1380 1390 1400
ASLLTVALHG KLEYYTDIMH TLFLELLEQY VVAKNPKLML RRSETVVERM
1410 1420 1430 1440 1450
LSNWMSICLY QYLKDSAGEP LYKLFKAIKH QVEKGPVDAV QKKAKYTLND
1460 1470 1480 1490 1500
TGLLGDDVEY APLTVSVIVQ DEGVDAIPVK VLNCDTISQV KEKIIDQVYR
1510 1520 1530 1540 1550
GQPCSCWPRP DSVVLEWRPG STAQILSDLD LTSQREGRWK RVNTLMHYNV
1560 1570 1580 1590 1600
RDGATLILSK VGVSQQPEDS QQDLPGERHA LLEEENRVWH LVRPTDEVDE
1610 1620 1630 1640 1650
GKSKRGSVKE KERTKAITEI YLTRLLSVKG TLQQFVDNFF QSVLAPGHAV
1660 1670 1680 1690 1700
PPAVKYFFDF LDEQAEKHNI QDEDTIHIWK TNSLPLRFWV NILKNPHFIF
1710 1720 1730 1740 1750
DVHVHEVVDA SLSVIAQTFM DACTRTEHKL SRDSPSNKLL YAKEISTYKK
1760 1770 1780 1790 1800
MVEDYYKGIR QMVQVSDQDM NTHLAEISRA HTDSLNTLVA LHQLYQYTQK
1810 1820 1830
YYDEIINALE EDPAAQKMQL AFRLQQIAAA LENKVTDL
Computationally mapped potential isoform sequencesi
There are 5 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basketE2PU09 | E2PU09_HUMAN | Plexin-B2 | PLXNB2 | 477 | Annotation score: | ||
A6QRH1 | A6QRH1_HUMAN | Plexin-B2 | PLXNB2 | 161 | Annotation score: | ||
H0Y6J7 | H0Y6J7_HUMAN | Plexin-B2 | PLXNB2 | 189 | Annotation score: | ||
A6QRG9 | A6QRG9_HUMAN | Plexin-B2 | PLXNB2 | 234 | Annotation score: | ||
H0Y7X5 | H0Y7X5_HUMAN | Plexin-B2 | PLXNB2 | 84 | Annotation score: |
Sequence cautioni
Experimental Info
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Sequence conflicti | 1535 | R → Q in AAH04542 (PubMed:15489334).Curated | 1 | |
Sequence conflicti | 1535 | R → Q in AAP35533 (Ref. 4) Curated | 1 |
Natural variant
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Natural variantiVAR_050600 | 318 | K → ECombined sourcesCorresponds to variant dbSNP:rs28379706Ensembl. | 1 | |
Natural variantiVAR_061537 | 823 | I → V. Corresponds to variant dbSNP:rs11547731Ensembl. | 1 |
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AB002313 mRNA Translation: BAA21571.1 Different initiation. AL022328 Genomic DNA No translation available. BX649592 Genomic DNA No translation available. BC004542 mRNA Translation: AAH04542.2 BT006887 mRNA Translation: AAP35533.1 |
CCDSi | CCDS43035.1 |
RefSeqi | NP_036533.2, NM_012401.3 XP_005261966.1, XM_005261909.1 XP_005261967.1, XM_005261910.2 XP_005261968.1, XM_005261911.4 XP_006724476.1, XM_006724413.2 XP_016884192.1, XM_017028703.1 XP_016884193.1, XM_017028704.1 |
Genome annotation databases
Ensembli | ENST00000359337.9; ENSP00000352288.4; ENSG00000196576.16 ENST00000449103.5; ENSP00000409171.1; ENSG00000196576.16 |
GeneIDi | 23654 |
KEGGi | hsa:23654 |
MANE-Selecti | ENST00000359337.9; ENSP00000352288.4; NM_012401.4; NP_036533.2 |
UCSCi | uc003bkv.4, human |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AB002313 mRNA Translation: BAA21571.1 Different initiation. AL022328 Genomic DNA No translation available. BX649592 Genomic DNA No translation available. BC004542 mRNA Translation: AAH04542.2 BT006887 mRNA Translation: AAP35533.1 |
CCDSi | CCDS43035.1 |
RefSeqi | NP_036533.2, NM_012401.3 XP_005261966.1, XM_005261909.1 XP_005261967.1, XM_005261910.2 XP_005261968.1, XM_005261911.4 XP_006724476.1, XM_006724413.2 XP_016884192.1, XM_017028703.1 XP_016884193.1, XM_017028704.1 |
3D structure databases
Select the link destinations: PDBei RCSB PDBi PDBji Links Updated | PDB entry | Method | Resolution (Å) | Chain | Positions | PDBsum |
4E71 | X-ray | 2.26 | A | 1452-1562 | [»] | |
AlphaFoldDBi | O15031 | |||||
SMRi | O15031 | |||||
ModBasei | Search... | |||||
PDBe-KBi | Search... |
Protein-protein interaction databases
BioGRIDi | 117178, 199 interactors |
IntActi | O15031, 44 interactors |
MINTi | O15031 |
STRINGi | 9606.ENSP00000409171 |
PTM databases
GlyConnecti | 1613, 57 N-Linked glycans (11 sites) |
GlyGeni | O15031, 16 sites, 56 N-linked glycans (11 sites), 1 O-linked glycan (1 site) |
iPTMneti | O15031 |
PhosphoSitePlusi | O15031 |
SwissPalmi | O15031 |
Genetic variation databases
BioMutai | PLXNB2 |
Proteomic databases
CPTACi | CPTAC-1504 CPTAC-2603 |
EPDi | O15031 |
jPOSTi | O15031 |
MassIVEi | O15031 |
MaxQBi | O15031 |
PaxDbi | O15031 |
PeptideAtlasi | O15031 |
PRIDEi | O15031 |
ProteomicsDBi | 48388 |
Protocols and materials databases
Antibodypediai | 322, 151 antibodies from 22 providers |
DNASUi | 23654 |
Genome annotation databases
Ensembli | ENST00000359337.9; ENSP00000352288.4; ENSG00000196576.16 ENST00000449103.5; ENSP00000409171.1; ENSG00000196576.16 |
GeneIDi | 23654 |
KEGGi | hsa:23654 |
MANE-Selecti | ENST00000359337.9; ENSP00000352288.4; NM_012401.4; NP_036533.2 |
UCSCi | uc003bkv.4, human |
Organism-specific databases
CTDi | 23654 |
DisGeNETi | 23654 |
GeneCardsi | PLXNB2 |
HGNCi | HGNC:9104, PLXNB2 |
HPAi | ENSG00000196576, Low tissue specificity |
MIMi | 604293, gene |
neXtProti | NX_O15031 |
OpenTargetsi | ENSG00000196576 |
PharmGKBi | PA33430 |
VEuPathDBi | HostDB:ENSG00000196576 |
HUGEi | Search... |
GenAtlasi | Search... |
Phylogenomic databases
eggNOGi | KOG3610, Eukaryota |
GeneTreei | ENSGT01020000230394 |
HOGENOMi | CLU_001436_1_0_1 |
InParanoidi | O15031 |
OMAi | CTPPIDE |
OrthoDBi | 90434at2759 |
PhylomeDBi | O15031 |
TreeFami | TF312962 |
Enzyme and pathway databases
PathwayCommonsi | O15031 |
SignaLinki | O15031 |
Miscellaneous databases
BioGRID-ORCSi | 23654, 23 hits in 1077 CRISPR screens |
ChiTaRSi | PLXNB2, human |
GeneWikii | PLXNB2 |
GenomeRNAii | 23654 |
Pharosi | O15031, Tbio |
PROi | PR:O15031 |
RNActi | O15031, protein |
SOURCEi | Search... |
Gene expression databases
Bgeei | ENSG00000196576, Expressed in right uterine tube and 229 other tissues |
ExpressionAtlasi | O15031, baseline and differential |
Genevisiblei | O15031, HS |
Family and domain databases
Gene3Di | 1.10.506.10, 1 hit 2.130.10.10, 1 hit 2.60.40.10, 3 hits |
InterProi | View protein in InterPro IPR013783, Ig-like_fold IPR014756, Ig_E-set IPR002909, IPT_dom IPR031148, Plexin IPR013548, Plexin_cytoplasmic_RasGAP_dom IPR002165, Plexin_repeat IPR016201, PSI IPR008936, Rho_GTPase_activation_prot IPR001627, Semap_dom IPR036352, Semap_dom_sf IPR041019, TIG1_plexin IPR015943, WD40/YVTN_repeat-like_dom_sf |
PANTHERi | PTHR22625, PTHR22625, 1 hit |
Pfami | View protein in Pfam PF08337, Plexin_cytopl, 1 hit PF01437, PSI, 1 hit PF01403, Sema, 1 hit PF01833, TIG, 3 hits PF17960, TIG_plexin, 1 hit |
SMARTi | View protein in SMART SM00429, IPT, 3 hits SM00423, PSI, 3 hits SM00630, Sema, 1 hit |
SUPFAMi | SSF101912, SSF101912, 1 hit SSF48350, SSF48350, 1 hit SSF81296, SSF81296, 3 hits |
PROSITEi | View protein in PROSITE PS51004, SEMA, 1 hit |
MobiDBi | Search... |
Entry informationi
Entry namei | PLXB2_HUMAN | |
Accessioni | O15031Primary (citable) accession number: O15031 Secondary accession number(s): A6QRH0, Q7KZU3, Q9BSU7 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | August 31, 2004 |
Last sequence update: | February 20, 2007 | |
Last modified: | May 25, 2022 | |
This is version 180 of the entry and version 3 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Chordata Protein Annotation Program | |
Disclaimer | Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. |
Miscellaneousi
Keywords - Technical termi
3D-structure, Reference proteomeDocuments
- Human chromosome 22
Human chromosome 22: entries, gene names and cross-references to MIM - Human entries with genetic variants
List of human entries with genetic variants - Human variants curated from literature reports
Index of human variants curated from literature reports - MIM cross-references
Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot - PDB cross-references
Index of Protein Data Bank (PDB) cross-references - SIMILARITY comments
Index of protein domains and families