UniProtKB - O14978 (ZN263_HUMAN)

BLAST

>sp|O14978|ZN263_HUMAN Zinc finger protein 263 OS=Homo sapiens OX=9606 GN=ZNF263 PE=1 SV=2
MASGPGSQEREGLLIVKLEEDCAWSQELPPPDPGPSPEASHLRFRRFRFQEAAGPREALS
RLQELCHGWLRPEMRTKEQILELLVLEQFLTILPQEIQSRVQELHPESGEEAVTLVEDMQ
RELGRLRQQVTNHGRGTEVLLEEPLPLETARESPSFKLEPMETERSPGPRLQELLGPSPQ
RDPQAVKERALSAPWLSLFPPEGNMEDKEMTGPQLPESLEDVAMYISQEEWGHQDPSKRA
LSRDTVQESYENVDSLESHIPSQEVPGTQVGQGGKLWDPSVQSCKEGLSPRGPAPGEEKF
ENLEGVPSVCSENIHPQVLLPDQARGEVPWSPELGRPHDRSQGDWAPPPEGGMEQALAGA
SSGRELGRPKELQPKKLHLCPLCGKNFSNNSNLIRHQRIHAAERLCMGVDCTEIFGGNPR
FLSLHRAHLGEEAHKCLECGKCFSQNTHLTRHQRTHTGEKPYQCNICGKCFSCNSNLHRH
QRTHTGEKPYKCPECGEIFAHSSNLLRHQRIHTGERPYKCPECGKSFSRSSHLVIHERTH
ERERLYPFSECGEAVSDSTPFLTNHGAHKAEKKLFECLTCGKSFRQGMHLTRHQRTHTGE
KPYKCTLCGENFSHRSNLIRHQRIHTGEKPYTCHECGDSFSHSSNRIRHLRTHTGERPYK
CSECGESFSRSSRLMSHQRTHTG

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History
Entry version 169 (07 Nov 2018)
Sequence version 2 (25 Oct 2002)
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Protein

Zinc finger protein 263

Gene

ZNF263

Organism

Homo sapiens (Human)

Status

Reviewed-Annotation score: -Experimental evidence at protein levelⁱ

Functionⁱ

Might play an important role in basic cellular processes as a transcriptional repressor.

Regions

Feature key	Position(s)	DescriptionActions	Length
Zinc fingerⁱ	378 – 400	C2H2-type 1PROSITE-ProRule annotationAdd BLAST	23
Zinc fingerⁱ	434 – 456	C2H2-type 2PROSITE-ProRule annotationAdd BLAST	23
Zinc fingerⁱ	462 – 484	C2H2-type 3PROSITE-ProRule annotationAdd BLAST	23
Zinc fingerⁱ	490 – 512	C2H2-type 4PROSITE-ProRule annotationAdd BLAST	23
Zinc fingerⁱ	518 – 540	C2H2-type 5PROSITE-ProRule annotationAdd BLAST	23
Zinc fingerⁱ	575 – 597	C2H2-type 6PROSITE-ProRule annotationAdd BLAST	23
Zinc fingerⁱ	603 – 625	C2H2-type 7PROSITE-ProRule annotationAdd BLAST	23
Zinc fingerⁱ	631 – 653	C2H2-type 8PROSITE-ProRule annotationAdd BLAST	23
Zinc fingerⁱ	659 – 681	C2H2-type 9PROSITE-ProRule annotationAdd BLAST	23

GO - Molecular functionⁱ

DNA-binding transcription factor activity
Source: ProtInc
Traceable author statementⁱ
- 9256059
DNA-binding transcription factor activity, RNA polymerase II-specific Source: NTNU_SB
DNA-binding transcription repressor activity, RNA polymerase II-specific Source: NTNU_SB
metal ion binding Source: UniProtKB-KW
sequence-specific DNA binding
Source: NTNU_SB
Inferred from direct assayⁱ
- 28473536

View the complete GO annotation on QuickGO ...

GO - Biological processⁱ

negative regulation of transcription, DNA-templated
Source: GO_Central
Inferred from biological aspect of ancestorⁱ
- 21873635
negative regulation of transcription by RNA polymerase II
Source: NTNU_SB
Inferred from direct assayⁱ
- 19887448
regulation of transcription, DNA-templated
Source: ProtInc
Traceable author statementⁱ
- 9256059

View the complete GO annotation on QuickGO ...

Keywordsⁱ

Molecular function	DNA-binding, Repressor
Biological process	Transcription, Transcription regulation
Ligand	Metal-binding, Zinc

Enzyme and pathway databases

Reactomeⁱ	R-HSA-212436 Generic Transcription Pathway
SignaLinkⁱ	O14978

Names & Taxonomyⁱ

Protein namesⁱ	Recommended name: Zinc finger protein 263 Alternative name(s): Zinc finger protein FPM315 Zinc finger protein with KRAB and SCAN domains 12
Gene namesⁱ	Name:ZNF263 Synonyms:FPM315, ZKSCAN12
Organismⁱ	Homo sapiens (Human)
Taxonomic identifierⁱ	9606 [NCBI]
Taxonomic lineageⁱ	cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Dipnotetrapodomorpha › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Boreoeutheria › Euarchontoglires › Primates › Haplorrhini › Simiiformes › Catarrhini › Hominoidea › Hominidae › Homininae › Homo
Proteomesⁱ	UP000005640 Componentⁱ: Chromosome 16

Organism-specific databases

EuPathDBⁱ	HostDB:ENSG00000006194.9
Human Gene Nomenclature Database More...HGNCⁱ	HGNC:13056 ZNF263
MIMⁱ	604191 gene
neXtProtⁱ	NX_O14978

Keywords - Cellular componentⁱ

Nucleus

Pathology & Biotechⁱ

Organism-specific databases

Open Targets More...OpenTargetsⁱ	ENSG00000006194
PharmGKBⁱ	PA37634

Polymorphism and mutation databases

BioMutaⁱ	ZNF263

BioMutaⁱ

ZNF263

PTM / Processingⁱ

Molecule processing

Feature key	Position(s)	DescriptionActions	Graphical view	Length
ChainⁱPRO_0000047491	1 – 683	Zinc finger protein 263Add BLAST		683

Amino acid modifications

Feature key	Position(s)	DescriptionActions	Length
Cross-linkⁱ	17	Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)Combined sources
Cross-linkⁱ	157	Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)Combined sources
Modified residueⁱ	166	PhosphoserineCombined sources	1
Modified residueⁱ	178	PhosphoserineCombined sources	1
Cross-linkⁱ	285	Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)Combined sources
Cross-linkⁱ	299	Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)Combined sources
Cross-linkⁱ	376	Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)Combined sources
Cross-linkⁱ	573	Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)Combined sources
Cross-linkⁱ	582	Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)Combined sources

Keywords - PTMⁱ

Isopeptide bond, Phosphoprotein, Ubl conjugation

Proteomic databases

EPDⁱ	O14978
MaxQB - The MaxQuant DataBase More...MaxQBⁱ	O14978
PaxDbⁱ	O14978
PeptideAtlas More...PeptideAtlasⁱ	O14978
PRIDEⁱ	O14978
ProteomicsDBⁱ	48352

PTM databases

iPTMnetⁱ	O14978
PhosphoSitePlusⁱ	O14978

Expressionⁱ

Tissue specificityⁱ

Expressed in heart, brain, placenta, lung, liver, skeletal muscle, kidney, pancreas, spleen, thymus, prostate, testis, ovary, small intestine, colon and leukocyte.

Gene expression databases

Bgeeⁱ	ENSG00000006194 Expressed in 219 organ(s), highest expression level in pituitary gland
CleanExⁱ	HS_ZNF263
ExpressionAtlasⁱ	O14978 baseline and differential
Genevisibleⁱ	O14978 HS

Organism-specific databases

Human Protein Atlas More...HPAⁱ	HPA035085 HPA035086

HPAⁱ

HPA035085
HPA035086

Interactionⁱ

Binary interactionsⁱ

With	Entry	#Exp.	IntAct
CLK2	P49760	3	EBI-744493,EBI-750020
CLK3	P49761	3	EBI-744493,EBI-745579
GPATCH2L	Q9NWQ4	3	EBI-744493,EBI-5666657
SCAND1	P57086	3	EBI-744493,EBI-745846
TCAF1	Q9Y4C2	3	EBI-744493,EBI-750484
TRIM41	Q8WV44	3	EBI-744493,EBI-725997

Protein-protein interaction databases

BioGridⁱ	115431, 72 interactors
IntActⁱ	O14978, 18 interactors
STRINGⁱ	9606.ENSP00000219069

Structureⁱ

3D structure databases

ProteinModelPortalⁱ	O14978
SMRⁱ	O14978
ModBaseⁱ	Search...
MobiDBⁱ	Search...

Family & Domainsⁱ

Domains and Repeats

Feature key	Position(s)	DescriptionActions	Graphical view	Length
Domainⁱ	41 – 123	SCAN boxPROSITE-ProRule annotationAdd BLAST		83
Domainⁱ	217 – 289	KRABPROSITE-ProRule annotationAdd BLAST		73

Sequence similaritiesⁱ

Belongs to the krueppel C2H2-type zinc-finger protein family.Curated

Zinc finger

Feature key	Position(s)	DescriptionActions	Length
Zinc fingerⁱ	378 – 400	C2H2-type 1PROSITE-ProRule annotationAdd BLAST	23
Zinc fingerⁱ	434 – 456	C2H2-type 2PROSITE-ProRule annotationAdd BLAST	23
Zinc fingerⁱ	462 – 484	C2H2-type 3PROSITE-ProRule annotationAdd BLAST	23
Zinc fingerⁱ	490 – 512	C2H2-type 4PROSITE-ProRule annotationAdd BLAST	23
Zinc fingerⁱ	518 – 540	C2H2-type 5PROSITE-ProRule annotationAdd BLAST	23
Zinc fingerⁱ	575 – 597	C2H2-type 6PROSITE-ProRule annotationAdd BLAST	23
Zinc fingerⁱ	603 – 625	C2H2-type 7PROSITE-ProRule annotationAdd BLAST	23
Zinc fingerⁱ	631 – 653	C2H2-type 8PROSITE-ProRule annotationAdd BLAST	23
Zinc fingerⁱ	659 – 681	C2H2-type 9PROSITE-ProRule annotationAdd BLAST	23

Keywords - Domainⁱ

Repeat, Zinc-finger

Phylogenomic databases

eggNOGⁱ	KOG1721 Eukaryota COG5048 LUCA
Ensembl GeneTree More...GeneTreeⁱ	ENSGT00910000144000
HOGENOMⁱ	HOG000234619
HOVERGENⁱ	HBG018163
InParanoidⁱ	O14978
KEGG Orthology (KO) More...KOⁱ	K09229
OMAⁱ	YPFSECG
Database of Orthologous Groups More...OrthoDBⁱ	EOG091G02UG
PhylomeDBⁱ	O14978
TreeFamⁱ	TF350829

Family and domain databases

Conserved Domains Database More...CDDⁱ	cd07765 KRAB_A-box, 1 hit cd07936 SCAN, 1 hit
Gene3Dⁱ	1.10.4020.10, 1 hit
InterProⁱ	View protein in InterPro IPR001909 KRAB IPR036051 KRAB_dom_sf IPR003309 SCAN_dom IPR038269 SCAN_sf IPR036236 Znf_C2H2_sf IPR013087 Znf_C2H2_type
Pfam protein domain database More...Pfamⁱ	View protein in Pfam PF01352 KRAB, 1 hit PF02023 SCAN, 1 hit PF00096 zf-C2H2, 9 hits
SMARTⁱ	View protein in SMART SM00349 KRAB, 1 hit SM00431 SCAN, 1 hit SM00355 ZnF_C2H2, 9 hits
SUPFAMⁱ	SSF109640 SSF109640, 1 hit SSF57667 SSF57667, 6 hits
PROSITEⁱ	View protein in PROSITE PS50805 KRAB, 1 hit PS50804 SCAN_BOX, 1 hit PS00028 ZINC_FINGER_C2H2_1, 9 hits PS50157 ZINC_FINGER_C2H2_2, 9 hits

Sequence (1+)ⁱ

Sequence statusⁱ: Complete.

This entry has 1 described isoform and 7 potential isoforms that are computationally mapped.Show all Align All

O14978-1 [UniParc]FASTA Add to basket

« Hide

        10         20         30         40         50
MASGPGSQER EGLLIVKLEE DCAWSQELPP PDPGPSPEAS HLRFRRFRFQ 
        60         70         80         90        100
EAAGPREALS RLQELCHGWL RPEMRTKEQI LELLVLEQFL TILPQEIQSR 
       110        120        130        140        150
VQELHPESGE EAVTLVEDMQ RELGRLRQQV TNHGRGTEVL LEEPLPLETA 
       160        170        180        190        200
RESPSFKLEP METERSPGPR LQELLGPSPQ RDPQAVKERA LSAPWLSLFP 
       210        220        230        240        250
PEGNMEDKEM TGPQLPESLE DVAMYISQEE WGHQDPSKRA LSRDTVQESY 
       260        270        280        290        300
ENVDSLESHI PSQEVPGTQV GQGGKLWDPS VQSCKEGLSP RGPAPGEEKF 
       310        320        330        340        350
ENLEGVPSVC SENIHPQVLL PDQARGEVPW SPELGRPHDR SQGDWAPPPE 
       360        370        380        390        400
GGMEQALAGA SSGRELGRPK ELQPKKLHLC PLCGKNFSNN SNLIRHQRIH 
       410        420        430        440        450
AAERLCMGVD CTEIFGGNPR FLSLHRAHLG EEAHKCLECG KCFSQNTHLT 
       460        470        480        490        500
RHQRTHTGEK PYQCNICGKC FSCNSNLHRH QRTHTGEKPY KCPECGEIFA 
       510        520        530        540        550
HSSNLLRHQR IHTGERPYKC PECGKSFSRS SHLVIHERTH ERERLYPFSE 
       560        570        580        590        600
CGEAVSDSTP FLTNHGAHKA EKKLFECLTC GKSFRQGMHL TRHQRTHTGE 
       610        620        630        640        650
KPYKCTLCGE NFSHRSNLIR HQRIHTGEKP YTCHECGDSF SHSSNRIRHL 
       660        670        680 
RTHTGERPYK CSECGESFSR SSRLMSHQRT HTG

Length:683

Mass (Da):77,299

Last modified:October 25, 2002 - v2

Checksum:ⁱ1E02C862FCE69265

Computationally mapped potential isoform sequencesⁱ

There are 7 potential isoforms mapped to this entry.BLAST Align Show all Add to basket

Entry	Entry name	Protein names	Gene names	Length	Annotation

I3NI39	I3NI39_HUMAN	Zinc finger protein 263 Zinc finger protein 263	ZNF263	141	Annotation score:
I3L393	I3L393_HUMAN	Zinc finger protein 263 Zinc finger protein 263	ZNF263	149	Annotation score:
I3L2X3	I3L2X3_HUMAN	Zinc finger protein 263 Zinc finger protein 263	ZNF263	226	Annotation score:
I3L0N0	I3L0N0_HUMAN	Zinc finger protein 263 Zinc finger protein 263	ZNF263	115	Annotation score:
B4DI05	B4DI05_HUMAN	cDNA FLJ57935, highly similar to Zi... cDNA FLJ57935, highly similar to Zinc finger protein 263	ZNF263	331	Annotation score:
I3L538	I3L538_HUMAN	Zinc finger protein 263 Zinc finger protein 263	ZNF263	51	Annotation score:
I3L4C4	I3L4C4_HUMAN	Zinc finger protein 263 Zinc finger protein 263	ZNF263	115	Annotation score:

Experimental Info

Feature key	Position(s)	DescriptionActions	Graphical view	Length
Sequence conflictⁱ	118	D → G in BAA21853 (PubMed:9256059).Curated		1

Natural variant

Feature key	Position(s)	DescriptionActions	Length
Natural variantⁱVAR_052801	310	C → S. Corresponds to variant dbSNP:rs220379Ensembl.	1
Natural variantⁱVAR_052802	534	V → I. Corresponds to variant dbSNP:rs34236132Ensembl.	1
Natural variantⁱVAR_061943	646	R → Q. Corresponds to variant dbSNP:rs57710602Ensembl.	1

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	D88827 mRNA Translation: BAA21853.1 AK312421 mRNA Translation: BAG35331.1 AC004232 Genomic DNA Translation: AAC24490.1 CH471112 Genomic DNA Translation: EAW85379.1 BC008805 mRNA Translation: AAH08805.1
The Consensus CDS (CCDS) project More...CCDSⁱ	CCDS10499.1
NCBI Reference Sequences More...RefSeqⁱ	NP_005732.2, NM_005741.4
UniGeneⁱ	Hs.611475

Genome annotation databases

Ensemblⁱ	ENST00000219069; ENSP00000219069; ENSG00000006194
GeneIDⁱ	10127
KEGGⁱ	hsa:10127
UCSC genome browser More...UCSCⁱ	uc002cuq.4 human

Keywords - Coding sequence diversityⁱ

Polymorphism

Similar proteinsⁱ

100% Identity
90% Identity
50% Identity

Protein	Similar proteins		Species	Score	Length	Source
O14978	cDNA FLJ57935, highly similar to Zinc finger protein 263		HUMAN		331	UniRef100_O14978
ZNF263 isoform 4		PANTR		331
UPI0003EB052A		HUMAN		479

Protein	Similar proteins		Species	Score	Length	Source
O14978	cDNA FLJ57935, highly similar to Zinc finger protein 263		HUMAN		331	UniRef90_O14978
ZNF263 isoform 4		PANTR		331
Uncharacterized protein		ICTTR		686
Zinc finger protein 263-like protein (Fragment)		HORSE		99
Zinc finger protein 263		MACMU		684
+65

Protein	Similar proteins		Species	Score	Length	Source
O14978	cDNA FLJ57935, highly similar to Zinc finger protein 263		HUMAN		331	UniRef50_O14978
ZNF263 isoform 4		PANTR		331
Uncharacterized protein		ICTTR		686
Zinc finger protein 263-like protein (Fragment)		HORSE		99
Zinc finger protein 263		MACNE		684
+249

Cross-referencesⁱ

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	D88827 mRNA Translation: BAA21853.1 AK312421 mRNA Translation: BAG35331.1 AC004232 Genomic DNA Translation: AAC24490.1 CH471112 Genomic DNA Translation: EAW85379.1 BC008805 mRNA Translation: AAH08805.1
CCDSⁱ	CCDS10499.1
RefSeqⁱ	NP_005732.2, NM_005741.4
UniGeneⁱ	Hs.611475

3D structure databases

ProteinModelPortalⁱ	O14978
SMRⁱ	O14978
ModBaseⁱ	Search...
MobiDBⁱ	Search...

Protein-protein interaction databases

BioGridⁱ	115431, 72 interactors
IntActⁱ	O14978, 18 interactors
STRINGⁱ	9606.ENSP00000219069

PTM databases

iPTMnetⁱ	O14978
PhosphoSitePlusⁱ	O14978

Polymorphism and mutation databases

BioMutaⁱ	ZNF263

BioMutaⁱ

ZNF263

Proteomic databases

EPDⁱ	O14978
MaxQBⁱ	O14978
PaxDbⁱ	O14978
PeptideAtlasⁱ	O14978
PRIDEⁱ	O14978
ProteomicsDBⁱ	48352

Protocols and materials databases

The DNASU plasmid repository More...DNASUⁱ	10127
Structural Biology Knowledgebase	Search...

Genome annotation databases

Ensemblⁱ	ENST00000219069; ENSP00000219069; ENSG00000006194
GeneIDⁱ	10127
KEGGⁱ	hsa:10127
UCSCⁱ	uc002cuq.4 human

Organism-specific databases

CTDⁱ	10127
EuPathDBⁱ	HostDB:ENSG00000006194.9
GeneCardsⁱ	ZNF263
HGNCⁱ	HGNC:13056 ZNF263
HPAⁱ	HPA035085 HPA035086
MIMⁱ	604191 gene
neXtProtⁱ	NX_O14978
OpenTargetsⁱ	ENSG00000006194
PharmGKBⁱ	PA37634
GenAtlas: human gene database More...GenAtlasⁱ	Search...

Phylogenomic databases

eggNOGⁱ	KOG1721 Eukaryota COG5048 LUCA
GeneTreeⁱ	ENSGT00910000144000
HOGENOMⁱ	HOG000234619
HOVERGENⁱ	HBG018163
InParanoidⁱ	O14978
KOⁱ	K09229
OMAⁱ	YPFSECG
OrthoDBⁱ	EOG091G02UG
PhylomeDBⁱ	O14978
TreeFamⁱ	TF350829

Enzyme and pathway databases

Reactomeⁱ	R-HSA-212436 Generic Transcription Pathway
SignaLinkⁱ	O14978

Miscellaneous databases

ChiTaRSⁱ	ZNF263 human
GenomeRNAiⁱ	10127
Protein Ontology More...PROⁱ	PR:O14978
SOURCEⁱ	Search...

Gene expression databases

Bgeeⁱ	ENSG00000006194 Expressed in 219 organ(s), highest expression level in pituitary gland
CleanExⁱ	HS_ZNF263
ExpressionAtlasⁱ	O14978 baseline and differential
Genevisibleⁱ	O14978 HS

Family and domain databases

CDDⁱ	cd07765 KRAB_A-box, 1 hit cd07936 SCAN, 1 hit
Gene3Dⁱ	1.10.4020.10, 1 hit
InterProⁱ	View protein in InterPro IPR001909 KRAB IPR036051 KRAB_dom_sf IPR003309 SCAN_dom IPR038269 SCAN_sf IPR036236 Znf_C2H2_sf IPR013087 Znf_C2H2_type
Pfamⁱ	View protein in Pfam PF01352 KRAB, 1 hit PF02023 SCAN, 1 hit PF00096 zf-C2H2, 9 hits
SMARTⁱ	View protein in SMART SM00349 KRAB, 1 hit SM00431 SCAN, 1 hit SM00355 ZnF_C2H2, 9 hits
SUPFAMⁱ	SSF109640 SSF109640, 1 hit SSF57667 SSF57667, 6 hits
PROSITEⁱ	View protein in PROSITE PS50805 KRAB, 1 hit PS50804 SCAN_BOX, 1 hit PS00028 ZINC_FINGER_C2H2_1, 9 hits PS50157 ZINC_FINGER_C2H2_2, 9 hits
ProtoNetⁱ	Search...

Entry informationⁱ

Entry nameⁱ	ZN263_HUMAN
Accessionⁱ	O14978Primary (citable) accession number: O14978 Secondary accession number(s): B2R634, O43387, Q96H95
Entry historyⁱ	Integrated into UniProtKB/Swiss-Prot:	May 30, 2000
	Last sequence update:	October 25, 2002
	Last modified:	November 7, 2018
	This is version 169 of the entry and version 2 of the sequence. See complete history.
Entry statusⁱ	Reviewed (UniProtKB/Swiss-Prot)
Annotation program	Chordata Protein Annotation Program
Disclaimer	Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousⁱ

Keywords - Technical termⁱ

Complete proteome, Reference proteome

Documents

SIMILARITY comments
Index of protein domains and families
Human chromosome 16
Human chromosome 16: entries, gene names and cross-references to MIM
Human entries with polymorphisms or disease mutations
List of human entries with polymorphisms or disease mutations
Human polymorphisms and disease mutations
Index of human polymorphisms and disease mutations
MIM cross-references
Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot

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Supporting data

UniProtKB - O14978 (ZN263_HUMAN)

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Zinc finger protein 263

ZNF263

Select a section on the left to see content.

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Regions

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

Enzyme and pathway databases

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

Organism-specific databases

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Nucleus

Nucleus

Keywords - Cellular componenti

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

Polymorphism and mutation databases

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Amino acid modifications

Keywords - PTMi

Proteomic databases

PTM databases

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Organism-specific databases

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

<p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Zinc finger

Keywords - Domaini

Phylogenomic databases

Family and domain databases

Experimental Info

Natural variant

Sequence databases

Genome annotation databases

Keywords - Coding sequence diversityi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

3D structure databases

Protein-protein interaction databases

PTM databases

Polymorphism and mutation databases

Proteomic databases

Protocols and materials databases

Genome annotation databases

Organism-specific databases

Phylogenomic databases

Enzyme and pathway databases

Miscellaneous databases

Gene expression databases

Family and domain databases

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Documents

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Functionⁱ

GO - Molecular functionⁱ

GO - Biological processⁱ

Names & Taxonomyⁱ

Subcellular locationⁱ

Keywords - Cellular componentⁱ

Pathology & Biotechⁱ

PTM / Processingⁱ

Keywords - PTMⁱ

Expressionⁱ

Interactionⁱ

Structureⁱ

Family & Domainsⁱ

Sequence similaritiesⁱ

Keywords - Domainⁱ

Keywords - Coding sequence diversityⁱ

Cross-referencesⁱ

Entry informationⁱ

Miscellaneousⁱ

Keywords - Technical termⁱ