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Protein
Submitted name:

Discs, large homolog 4 (Drosophila), isoform CRA_d

Gene

DLG4

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Names & Taxonomyi

Protein namesi
Submitted name:
Discs, large homolog 4 (Drosophila), isoform CRA_dImported
Submitted name:
Disks large homolog 4Imported
Submitted name:
Tax interaction protein 15Imported
Gene namesi
Name:DLG4Imported
ORF Names:hCG_40530Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 17

Organism-specific databases

EuPathDBiHostDB:ENSG00000132535.18
HGNCiHGNC:2903 DLG4

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000132535

PTM / Processingi

Proteomic databases

EPDiO14909
MaxQBiO14909
PeptideAtlasiO14909
PRIDEiO14909

Expressioni

Gene expression databases

BgeeiENSG00000132535 Expressed in 146 organ(s), highest expression level in dorsolateral prefrontal cortex
ExpressionAtlasiO14909 baseline and differential

Interactioni

Protein-protein interaction databases

MINTiO14909

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini62 – 149PDZInterPro annotationAdd BLAST88
Domaini157 – 244PDZInterPro annotationAdd BLAST88

Phylogenomic databases

eggNOGiKOG0708 Eukaryota
COG0194 LUCA
GeneTreeiENSGT00760000118866
HOVERGENiHBG052815

Family and domain databases

InterProiView protein in InterPro
IPR019590 DLG1_PEST_dom
IPR001478 PDZ
IPR019583 PDZ_assoc
IPR036034 PDZ_sf
PfamiView protein in Pfam
PF10608 MAGUK_N_PEST, 1 hit
PF00595 PDZ, 2 hits
PF10600 PDZ_assoc, 1 hit
SMARTiView protein in SMART
SM01277 MAGUK_N_PEST, 1 hit
SM00228 PDZ, 2 hits
SUPFAMiSSF50156 SSF50156, 2 hits
PROSITEiView protein in PROSITE
PS50106 PDZ, 2 hits

Sequence (1+)i

Sequence statusi: Complete.

This entry has 1 described isoform and 6 potential isoforms that are computationally mapped.Show allAlign All

O14909-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MDCLCIVTTK KYRYQDEDTP PLEHSPAHLP NQANSPPVIV NTDTLEAPGY
60 70 80 90 100
VNGTEGEMEY EEITLERGNS GLGFSIAGGT DNPHIGDDPS IFITKIIPGG
110 120 130 140 150
AAAQDGRLRV NDSILFVNEV DVREVTHSAA VEALKEAGSI VRLYVMRRKP
160 170 180 190 200
PAEKVMEIKL IKGPKGLGFS IAGGVGNQHI PGDNSIYVTK IIEGGAAHKD
210 220 230 240 250
GRLQIGDKIL AVNSVGLEDV MHEDAVAALK NTYDVVYLKV AKPSNAYLSD
260 270 280 290
SYAPPDITTC ESPSNTKVPH DPSRLTHDMQ SHDIPVAVPL QIFPMK
Length:296
Mass (Da):31,914
Last modified:January 1, 1998 - v1
Checksum:iD8ABEE061CEF94DD
GO

Computationally mapped potential isoform sequencesi

There are 6 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
P78352DLG4_HUMAN
Disks large homolog 4
DLG4 PSD95
724Annotation score:
C9JWP9C9JWP9_HUMAN
Disks large homolog 4
DLG4
234Annotation score:
C9JYG3C9JYG3_HUMAN
Disks large homolog 4
DLG4
281Annotation score:
K7EKP9K7EKP9_HUMAN
Disks large homolog 4
DLG4
115Annotation score:
K7EQM6K7EQM6_HUMAN
Disks large homolog 4
DLG4
85Annotation score:
K7EKU8K7EKU8_HUMAN
Disks large homolog 4
DLG4
91Annotation score:

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei296Imported1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC120057 Genomic DNA No translation available.
AF028825 mRNA Translation: AAB84250.1
CH471108 Genomic DNA Translation: EAW90254.1
UniGeneiHs.463928

Genome annotation databases

EnsembliENST00000485100; ENSP00000460625; ENSG00000132535
UCSCiuc002geu.4 human

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC120057 Genomic DNA No translation available.
AF028825 mRNA Translation: AAB84250.1
CH471108 Genomic DNA Translation: EAW90254.1
UniGeneiHs.463928

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

MINTiO14909

Proteomic databases

EPDiO14909
MaxQBiO14909
PeptideAtlasiO14909
PRIDEiO14909

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000485100; ENSP00000460625; ENSG00000132535
UCSCiuc002geu.4 human

Organism-specific databases

EuPathDBiHostDB:ENSG00000132535.18
HGNCiHGNC:2903 DLG4
OpenTargetsiENSG00000132535
GenAtlasiSearch...

Phylogenomic databases

eggNOGiKOG0708 Eukaryota
COG0194 LUCA
GeneTreeiENSGT00760000118866
HOVERGENiHBG052815

Miscellaneous databases

ChiTaRSiDLG4 human

Gene expression databases

BgeeiENSG00000132535 Expressed in 146 organ(s), highest expression level in dorsolateral prefrontal cortex
ExpressionAtlasiO14909 baseline and differential

Family and domain databases

InterProiView protein in InterPro
IPR019590 DLG1_PEST_dom
IPR001478 PDZ
IPR019583 PDZ_assoc
IPR036034 PDZ_sf
PfamiView protein in Pfam
PF10608 MAGUK_N_PEST, 1 hit
PF00595 PDZ, 2 hits
PF10600 PDZ_assoc, 1 hit
SMARTiView protein in SMART
SM01277 MAGUK_N_PEST, 1 hit
SM00228 PDZ, 2 hits
SUPFAMiSSF50156 SSF50156, 2 hits
PROSITEiView protein in PROSITE
PS50106 PDZ, 2 hits
ProtoNetiSearch...

Entry informationi

Entry nameiO14909_HUMAN
AccessioniPrimary (citable) accession number: O14909
Entry historyiIntegrated into UniProtKB/TrEMBL: January 1, 1998
Last sequence update: January 1, 1998
Last modified: September 12, 2018
This is version 121 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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