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Protein

Secretory carrier-associated membrane protein 3

Gene

SCAMP3

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Functions in post-Golgi recycling pathways. Acts as a recycling carrier to the cell surface.

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

  • ubiquitin protein ligase binding Source: UniProtKB

GO - Biological processi

  • post-Golgi vesicle-mediated transport Source: ProtInc
  • protein transport Source: GO_Central

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Biological processProtein transport, Transport

Enzyme and pathway databases

SIGNOR Signaling Network Open Resource

More...
SIGNORi
O14828

Protein family/group databases

Transport Classification Database

More...
TCDBi
8.A.103.1.3 the secretory carrier-associated membrane protein (scamp) family

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Secretory carrier-associated membrane protein 3
Short name:
Secretory carrier membrane protein 3
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:SCAMP3
Synonyms:C1orf3, PROPIN1
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 1

Organism-specific databases

Eukaryotic Pathogen Database Resources

More...
EuPathDBi
HostDB:ENSG00000116521.10

Human Gene Nomenclature Database

More...
HGNCi
HGNC:10565 SCAMP3

Online Mendelian Inheritance in Man (OMIM)

More...
MIMi
606913 gene

neXtProt; the human protein knowledge platform

More...
neXtProti
NX_O14828

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/subcellular_location_section">'Subcellular location'</a> section describes the subcellular compartment where each non-membrane region of a membrane-spanning protein is found.<p><a href='/help/topo_dom' target='_top'>More...</a></p>Topological domaini1 – 170CytoplasmicSequence analysisAdd BLAST170
<p>This subsection of the <a href="http://www.uniprot.org/help/subcellular_location_section">'Subcellular location'</a> section describes the extent of a membrane-spanning region of the protein. It denotes the presence of both alpha-helical transmembrane regions and the membrane spanning regions of beta-barrel transmembrane proteins.<p><a href='/help/transmem' target='_top'>More...</a></p>Transmembranei171 – 191HelicalSequence analysisAdd BLAST21
Transmembranei197 – 217HelicalSequence analysisAdd BLAST21
Transmembranei247 – 267HelicalSequence analysisAdd BLAST21
Transmembranei277 – 297HelicalSequence analysisAdd BLAST21
Topological domaini298 – 347CytoplasmicSequence analysisAdd BLAST50

Keywords - Cellular componenti

Membrane

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Mutagenesis

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/manual/pathology_and_biotech_section">'Pathology and Biotech'</a> section describes the effect of the experimental mutation of one or more amino acid(s) on the biological properties of the protein.<p><a href='/help/mutagen' target='_top'>More...</a></p>Mutagenesisi67P → L: Abolishes interaction with TSG101. 1 Publication1

Organism-specific databases

DisGeNET

More...
DisGeNETi
10067

Open Targets

More...
OpenTargetsi
ENSG00000116521

The Pharmacogenetics and Pharmacogenomics Knowledge Base

More...
PharmGKBi
PA34978

Polymorphism and mutation databases

BioMuta curated single-nucleotide variation and disease association database

More...
BioMutai
SCAMP3

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00001912571 – 347Secretory carrier-associated membrane protein 3Add BLAST347

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section specifies the position and type of each modified residue excluding <a href="http://www.uniprot.org/manual/lipid">lipids</a>, <a href="http://www.uniprot.org/manual/carbohyd">glycans</a> and <a href="http://www.uniprot.org/manual/crosslnk">protein cross-links</a>.<p><a href='/help/mod_res' target='_top'>More...</a></p>Modified residuei32PhosphoserineCombined sources1
Modified residuei37PhosphothreonineCombined sources1
Modified residuei41PhosphotyrosineCombined sources1
Modified residuei53PhosphotyrosineCombined sources1
Modified residuei72PhosphoserineCombined sources1
Modified residuei76PhosphoserineCombined sources1
Modified residuei83PhosphotyrosineBy similarity1
Modified residuei85PhosphoserineCombined sources1
<p>This subsection of the <a href="http://www.uniprot.org/help/ptm_processing_section">PTM / Processing</a> section describes <strong>covalent linkages</strong> of various types formed <strong>between two proteins (interchain cross-links)</strong> or <strong>between two parts of the same protein (intrachain cross-links)</strong>, except the disulfide bonds that are annotated in the <a href="http://www.uniprot.org/manual/disulfid">'Disulfide bond'</a> subsection.<p><a href='/help/crosslnk' target='_top'>More...</a></p>Cross-linki313Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO1)Combined sources

<p>This subsection of the <a href="http://www.uniprot.org/help/ptm_processing_section">PTM/processing</a> section describes post-translational modifications (PTMs). This subsection <strong>complements</strong> the information provided at the sequence level or describes modifications for which <strong>position-specific data is not yet available</strong>.<p><a href='/help/post-translational_modification' target='_top'>More...</a></p>Post-translational modificationi

Monoubiquitinated.

Keywords - PTMi

Isopeptide bond, Phosphoprotein, Ubl conjugation

Proteomic databases

Encyclopedia of Proteome Dynamics

More...
EPDi
O14828

jPOST - Japan Proteome Standard Repository/Database

More...
jPOSTi
O14828

MaxQB - The MaxQuant DataBase

More...
MaxQBi
O14828

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
O14828

PeptideAtlas

More...
PeptideAtlasi
O14828

PRoteomics IDEntifications database

More...
PRIDEi
O14828

ProteomicsDB human proteome resource

More...
ProteomicsDBi
48259
48260 [O14828-2]

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
O14828

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...
PhosphoSitePlusi
O14828

SwissPalm database of S-palmitoylation events

More...
SwissPalmi
O14828

Miscellaneous databases

CutDB - Proteolytic event database

More...
PMAP-CutDBi
O14828

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

<p>This subsection of the ‘Expression’ section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms. By default, the information is derived from experiments at the mRNA level, unless specified ‘at protein level’. <br></br>Examples: <a href="http://www.uniprot.org/uniprot/P92958#expression">P92958</a>, <a href="http://www.uniprot.org/uniprot/Q8TDN4#expression">Q8TDN4</a>, <a href="http://www.uniprot.org/uniprot/O14734#expression">O14734</a><p><a href='/help/tissue_specificity' target='_top'>More...</a></p>Tissue specificityi

Widely expressed, with highest expression in heart and skeletal muscle.

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSG00000116521 Expressed in 220 organ(s), highest expression level in left adrenal gland

CleanEx database of gene expression profiles

More...
CleanExi
HS_SCAMP3

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
O14828 HS

Organism-specific databases

Human Protein Atlas

More...
HPAi
HPA071167

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the <a href="http://www.uniprot.org/help/interaction_section">'Interaction'</a> section provides information about the protein quaternary structure and interaction(s) with other proteins or protein complexes (with the exception of physiological receptor-ligand interactions which are annotated in the <a href="http://www.uniprot.org/help/function_section">'Function'</a> section).<p><a href='/help/subunit_structure' target='_top'>More...</a></p>Subunit structurei

Interacts with NEDD4, NEDD4L and TSG101. Interacts with RNF126.2 Publications

GO - Molecular functioni

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGrid)

More...
BioGridi
115378, 66 interactors

CORUM comprehensive resource of mammalian protein complexes

More...
CORUMi
O14828

The Eukaryotic Linear Motif resource for Functional Sites in Proteins

More...
ELMi
O14828

Protein interaction database and analysis system

More...
IntActi
O14828, 49 interactors

Molecular INTeraction database

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MINTi
O14828

STRING: functional protein association networks

More...
STRINGi
9606.ENSP00000307275

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

Protein Model Portal of the PSI-Nature Structural Biology Knowledgebase

More...
ProteinModelPortali
O14828

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
O14828

Database of comparative protein structure models

More...
ModBasei
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

<p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the SCAMP family.Curated

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG3088 Eukaryota
ENOG410XSJN LUCA

Ensembl GeneTree

More...
GeneTreei
ENSGT00940000160917

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
HOG000294221

The HOVERGEN Database of Homologous Vertebrate Genes

More...
HOVERGENi
HBG071938

InParanoid: Eukaryotic Ortholog Groups

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InParanoidi
O14828

KEGG Orthology (KO)

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KOi
K19995

Identification of Orthologs from Complete Genome Data

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OMAi
FIFFAQD

Database of Orthologous Groups

More...
OrthoDBi
995882at2759

Database for complete collections of gene phylogenies

More...
PhylomeDBi
O14828

TreeFam database of animal gene trees

More...
TreeFami
TF313797

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR007273 SCAMP

The PANTHER Classification System

More...
PANTHERi
PTHR10687 PTHR10687, 1 hit

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF04144 SCAMP, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>.<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequences (2)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry describes 2 <p>This subsection of the ‘Sequence’ section lists the alternative protein sequences (isoforms) that can be generated from the same gene by a single or by the combination of up to four biological events (alternative promoter usage, alternative splicing, alternative initiation and ribosomal frameshifting). Additionally, this section gives relevant information on each alternative protein isoform.<p><a href='/help/alternative_products' target='_top'>More...</a></p> isoformsi produced by alternative splicing. AlignAdd to basket
Isoform 1 (identifier: O14828-1) [UniParc]FASTAAdd to basket

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide
        10         20         30         40         50
MAQSRDGGNP FAEPSELDNP FQDPAVIQHR PSRQYATLDV YNPFETREPP
60 70 80 90 100
PAYEPPAPAP LPPPSAPSLQ PSRKLSPTEP KNYGSYSTQA SAAAATAELL
110 120 130 140 150
KKQEELNRKA EELDRREREL QHAALGGTAT RQNNWPPLPS FCPVQPCFFQ
160 170 180 190 200
DISMEIPQEF QKTVSTMYYL WMCSTLALLL NFLACLASFC VETNNGAGFG
210 220 230 240 250
LSILWVLLFT PCSFVCWYRP MYKAFRSDSS FNFFVFFFIF FVQDVLFVLQ
260 270 280 290 300
AIGIPGWGFS GWISALVVPK GNTAVSVLML LVALLFTGIA VLGIVMLKRI
310 320 330 340
HSLYRRTGAS FQKAQQEFAA GVFSNPAVRT AAANAAAGAA ENAFRAP
Length:347
Mass (Da):38,287
Last modified:September 23, 2008 - v3
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iD5B0870C66B84F9F
GO
Isoform 2 (identifier: O14828-2) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     23-48: Missing.

Note: No experimental confirmation available.
Show »
Length:321
Mass (Da):35,202
Checksum:i4F1819F7430A70C0
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti3Q → R in AAB62724 (PubMed:9378760).Curated1
Sequence conflicti74K → M in AAB62724 (PubMed:9378760).Curated1
Sequence conflicti331A → R in AAC51821 (PubMed:9331372).Curated1

Natural variant

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section describes natural variant(s) of the protein sequence.<p><a href='/help/variant' target='_top'>More...</a></p>Natural variantiVAR_01188538L → R1 PublicationCorresponds to variant dbSNP:rs760073Ensembl.1
Natural variantiVAR_011886235V → A1 PublicationCorresponds to variant dbSNP:rs1318328Ensembl.1
Natural variantiVAR_011887239I → N1 PublicationCorresponds to variant dbSNP:rs909106Ensembl.1
Natural variantiVAR_011888242V → D1 PublicationCorresponds to variant dbSNP:rs909107Ensembl.1

Alternative sequence

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section describes the sequence of naturally occurring alternative protein isoform(s). The changes in the amino acid sequence may be due to alternative splicing, alternative promoter usage, alternative initiation, or ribosomal frameshifting. The information stored in this subsection is used to automatically construct alternative protein sequence(s) for display.<p><a href='/help/var_seq' target='_top'>More...</a></p>Alternative sequenceiVSP_00438123 – 48Missing in isoform 2. 1 PublicationAdd BLAST26

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

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GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AF023268 Genomic DNA Translation: AAC51821.1
AF005039 mRNA Translation: AAB62724.1
AL713999 Genomic DNA No translation available.
CH471121 Genomic DNA Translation: EAW53090.1
CH471121 Genomic DNA Translation: EAW53092.1
BC000161 mRNA Translation: AAH00161.1
BC005135 mRNA Translation: AAH05135.1
BC010505 mRNA Translation: AAH10505.1

The Consensus CDS (CCDS) project

More...
CCDSi
CCDS1105.1 [O14828-1]
CCDS1106.1 [O14828-2]

Protein sequence database of the Protein Information Resource

More...
PIRi
T08826

NCBI Reference Sequences

More...
RefSeqi
NP_005689.2, NM_005698.3 [O14828-1]
NP_443069.1, NM_052837.2 [O14828-2]

UniGene gene-oriented nucleotide sequence clusters

More...
UniGenei
Hs.200600

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENST00000302631; ENSP00000307275; ENSG00000116521 [O14828-1]
ENST00000355379; ENSP00000347540; ENSG00000116521 [O14828-2]
ENST00000570831; ENSP00000461521; ENSG00000263290 [O14828-1]
ENST00000573013; ENSP00000458542; ENSG00000263290 [O14828-2]

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
10067

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
hsa:10067

UCSC genome browser

More...
UCSCi
uc001fjs.4 human [O14828-1]

Keywords - Coding sequence diversityi

Alternative splicing, Polymorphism

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF023268 Genomic DNA Translation: AAC51821.1
AF005039 mRNA Translation: AAB62724.1
AL713999 Genomic DNA No translation available.
CH471121 Genomic DNA Translation: EAW53090.1
CH471121 Genomic DNA Translation: EAW53092.1
BC000161 mRNA Translation: AAH00161.1
BC005135 mRNA Translation: AAH05135.1
BC010505 mRNA Translation: AAH10505.1
CCDSiCCDS1105.1 [O14828-1]
CCDS1106.1 [O14828-2]
PIRiT08826
RefSeqiNP_005689.2, NM_005698.3 [O14828-1]
NP_443069.1, NM_052837.2 [O14828-2]
UniGeneiHs.200600

3D structure databases

ProteinModelPortaliO14828
SMRiO14828
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi115378, 66 interactors
CORUMiO14828
ELMiO14828
IntActiO14828, 49 interactors
MINTiO14828
STRINGi9606.ENSP00000307275

Protein family/group databases

TCDBi8.A.103.1.3 the secretory carrier-associated membrane protein (scamp) family

PTM databases

iPTMnetiO14828
PhosphoSitePlusiO14828
SwissPalmiO14828

Polymorphism and mutation databases

BioMutaiSCAMP3

Proteomic databases

EPDiO14828
jPOSTiO14828
MaxQBiO14828
PaxDbiO14828
PeptideAtlasiO14828
PRIDEiO14828
ProteomicsDBi48259
48260 [O14828-2]

Protocols and materials databases

The DNASU plasmid repository

More...
DNASUi
10067
Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000302631; ENSP00000307275; ENSG00000116521 [O14828-1]
ENST00000355379; ENSP00000347540; ENSG00000116521 [O14828-2]
ENST00000570831; ENSP00000461521; ENSG00000263290 [O14828-1]
ENST00000573013; ENSP00000458542; ENSG00000263290 [O14828-2]
GeneIDi10067
KEGGihsa:10067
UCSCiuc001fjs.4 human [O14828-1]

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
10067
DisGeNETi10067
EuPathDBiHostDB:ENSG00000116521.10

GeneCards: human genes, protein and diseases

More...
GeneCardsi
SCAMP3
HGNCiHGNC:10565 SCAMP3
HPAiHPA071167
MIMi606913 gene
neXtProtiNX_O14828
OpenTargetsiENSG00000116521
PharmGKBiPA34978

GenAtlas: human gene database

More...
GenAtlasi
Search...

Phylogenomic databases

eggNOGiKOG3088 Eukaryota
ENOG410XSJN LUCA
GeneTreeiENSGT00940000160917
HOGENOMiHOG000294221
HOVERGENiHBG071938
InParanoidiO14828
KOiK19995
OMAiFIFFAQD
OrthoDBi995882at2759
PhylomeDBiO14828
TreeFamiTF313797

Enzyme and pathway databases

SIGNORiO14828

Miscellaneous databases

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

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ChiTaRSi
SCAMP3 human

The Gene Wiki collection of pages on human genes and proteins

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GeneWikii
SCAMP3

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

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GenomeRNAii
10067
PMAP-CutDBiO14828

Protein Ontology

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PROi
PR:O14828

The Stanford Online Universal Resource for Clones and ESTs

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SOURCEi
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Gene expression databases

BgeeiENSG00000116521 Expressed in 220 organ(s), highest expression level in left adrenal gland
CleanExiHS_SCAMP3
GenevisibleiO14828 HS

Family and domain databases

InterProiView protein in InterPro
IPR007273 SCAMP
PANTHERiPTHR10687 PTHR10687, 1 hit
PfamiView protein in Pfam
PF04144 SCAMP, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

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ProtoNeti
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<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiSCAM3_HUMAN
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: O14828
Secondary accession number(s): A9Z1W6
, B1AVS6, O15128, Q96FR8, Q9BPY0
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: December 15, 1998
Last sequence update: September 23, 2008
Last modified: January 16, 2019
This is version 177 of the entry and version 3 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
  2. Human entries with polymorphisms or disease mutations
    List of human entries with polymorphisms or disease mutations
  3. Human polymorphisms and disease mutations
    Index of human polymorphisms and disease mutations
  4. MIM cross-references
    Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
  5. Human chromosome 1
    Human chromosome 1: entries, gene names and cross-references to MIM
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