Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Entry version 141 (08 May 2019)
Sequence version 3 (25 Apr 2018)
Previous versions | rss
Other tutorials and videosHelp videoFeedback
Protein

Fucose-1-phosphate guanylyltransferase

Gene

FPGT

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Catalyzes the formation of GDP-L-fucose from GTP and L-fucose-1-phosphate. Functions as a salvage pathway to reutilize L-fucose arising from the turnover of glycoproteins and glycolipids.

<p>This subsection of the <a href="http://www.uniprot.org/help/function_section">Function</a> section describes the catalytic activity of an enzyme, i.e. a chemical reaction that the enzyme catalyzes.<p><a href='/help/catalytic_activity' target='_top'>More...</a></p>Catalytic activityi

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionNucleotidyltransferase, Transferase
LigandGTP-binding, Nucleotide-binding

Enzyme and pathway databases

BRENDA Comprehensive Enzyme Information System

More...
BRENDAi
2.7.7.30 2681

Reactome - a knowledgebase of biological pathways and processes

More...
Reactomei
R-HSA-6787639 GDP-fucose biosynthesis

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Fucose-1-phosphate guanylyltransferase (EC:2.7.7.30)
Alternative name(s):
GDP-L-fucose diphosphorylase
GDP-L-fucose pyrophosphorylase
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:FPGT
Synonyms:GFPP
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 1

Organism-specific databases

Human Gene Nomenclature Database

More...
HGNCi
HGNC:3825 FPGT

Online Mendelian Inheritance in Man (OMIM)

More...
MIMi
603609 gene

neXtProt; the human protein knowledge platform

More...
neXtProti
NX_O14772

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

Keywords - Cellular componenti

Cytoplasm

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

DisGeNET

More...
DisGeNETi
8790

Open Targets

More...
OpenTargetsi
ENSG00000254685

The Pharmacogenetics and Pharmacogenomics Knowledge Base

More...
PharmGKBi
PA28243

Polymorphism and mutation databases

BioMuta curated single-nucleotide variation and disease association database

More...
BioMutai
FPGT

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00000873271 – 607Fucose-1-phosphate guanylyltransferaseAdd BLAST607

Proteomic databases

Encyclopedia of Proteome Dynamics

More...
EPDi
O14772

jPOST - Japan Proteome Standard Repository/Database

More...
jPOSTi
O14772

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
O14772

PeptideAtlas

More...
PeptideAtlasi
O14772

PRoteomics IDEntifications database

More...
PRIDEi
O14772

ProteomicsDB human proteome resource

More...
ProteomicsDBi
48223

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
O14772

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...
PhosphoSitePlusi
O14772

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

<p>This subsection of the ‘Expression’ section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms. By default, the information is derived from experiments at the mRNA level, unless specified ‘at protein level’. <br></br>Examples: <a href="http://www.uniprot.org/uniprot/P92958#expression">P92958</a>, <a href="http://www.uniprot.org/uniprot/Q8TDN4#expression">Q8TDN4</a>, <a href="http://www.uniprot.org/uniprot/O14734#expression">O14734</a><p><a href='/help/tissue_specificity' target='_top'>More...</a></p>Tissue specificityi

Expressed in many tissues.

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSG00000254685 Expressed in 197 organ(s), highest expression level in sigmoid colon

ExpressionAtlas, Differential and Baseline Expression

More...
ExpressionAtlasi
O14772 baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
O14772 HS

Organism-specific databases

Human Protein Atlas

More...
HPAi
HPA072331

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGrid)

More...
BioGridi
114318, 1 interactor

STRING: functional protein association networks

More...
STRINGi
9606.ENSP00000359935

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
O14772

Database of comparative protein structure models

More...
ModBasei
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
ENOG410IE28 Eukaryota
ENOG410XT7S LUCA

Ensembl GeneTree

More...
GeneTreei
ENSGT00780000122095

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
HOG000067964

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
O14772

KEGG Orthology (KO)

More...
KOi
K00976

Identification of Orthologs from Complete Genome Data

More...
OMAi
DMIAYRE

Database of Orthologous Groups

More...
OrthoDBi
173077at2759

Database for complete collections of gene phylogenies

More...
PhylomeDBi
O14772

TreeFam database of animal gene trees

More...
TreeFami
TF328750

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR012887 Fucokinase
IPR012120 Fucose-1-phosphate_GuaTrfase
IPR011004 Trimer_LpxA-like_sf

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF07959 Fucokinase, 1 hit

PIRSF; a whole-protein classification database

More...
PIRSFi
PIRSF036640 FPGT, 1 hit

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF51161 SSF51161, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>.<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequences (6+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry describes 6 <p>This subsection of the ‘Sequence’ section lists the alternative protein sequences (isoforms) that can be generated from the same gene by a single or by the combination of up to four biological events (alternative promoter usage, alternative splicing, alternative initiation and ribosomal frameshifting). Additionally, this section gives relevant information on each alternative protein isoform.<p><a href='/help/alternative_products' target='_top'>More...</a></p> isoformsi produced by alternative splicing. AlignAdd to basket

This entry has 6 described isoforms and 4 potential isoforms that are computationally mapped.Show allAlign All

Isoform 2 (identifier: O14772-1) [UniParc]FASTAAdd to basket

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide
        10         20         30         40         50
MRAVRRGLRE GGAMAAARDP PEVSLREATQ RKLRRFSELR GKLVARGEFW
60 70 80 90 100
DIVAITAADE KQELAYNQQL SEKLKRKELP LGVQYHVFVD PAGAKIGNGG
110 120 130 140 150
STLCALQCLE KLYGDKWNSF TILLIHSGGY SQRLPNASAL GKIFTALPLG
160 170 180 190 200
NPIYQMLELK LAMYIDFPLN MNPGILVTCA DDIELYSIGE FEFIRFDKPG
210 220 230 240 250
FTALAHPSSL TIGTTHGVFV LDPFDDLKHR DLEYRSCHRF LHKPSIEKMY
260 270 280 290 300
QFNAVCRPGN FCQQDFAGGD IADLKLDSDY VYTDSLFYMD HKSAKMLLAF
310 320 330 340 350
YEKIGTLSCE IDAYGDFLQA LGPGATVEYT RNTSNVIKEE SELVEMRQRI
360 370 380 390 400
FHLLKGTSLN VVVLNNSKFY HIGTTEEYLF YFTSDNSLKS ELGLQSITFS
410 420 430 440 450
IFPDIPECSG KTSCIIQSIL DSRCSVAPGS VVEYSRLGPD VSVGENCIIS
460 470 480 490 500
GSYILTKAAL PAHSFVCSLS LKMNRCLKYA TMAFGVQDNL KKSVKTLSDI
510 520 530 540 550
KLLQFFGVCF LSCLDVWNLK VTEELFSGNK TCLSLWTARI FPVCSSLSDS
560 570 580 590 600
VITSLKMLNA VKNKSAFSLN SYKLLSIEEM LIYKDVEDMI TYREQIFLEI

SLKSSLM
Length:607
Mass (Da):68,010
Last modified:April 25, 2018 - v3
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i5175BB73A69255F1
GO
Isoform 1 (identifier: Q59H18-1) [UniParc]FASTAAdd to basket
The sequence of this isoform can be found in the external entry Q59H18.
Isoforms of the same protein are often annotated in two different entries if their sequences differ significantly.
Note: Based on a naturally occurring readthrough transcript which produces a FPGT-TNNI3K fusion protein.
Length:936
Mass (Da):104,179
GO
Isoform 3 (identifier: Q59H18-3) [UniParc]FASTAAdd to basket
The sequence of this isoform can be found in the external entry Q59H18.
Isoforms of the same protein are often annotated in two different entries if their sequences differ significantly.
Note: Based on a naturally occurring readthrough transcript which produces a FPGT-TNNI3K fusion protein.
Length:697
Mass (Da):77,957
GO
Isoform 4 (identifier: Q59H18-4) [UniParc]FASTAAdd to basket
The sequence of this isoform can be found in the external entry Q59H18.
Isoforms of the same protein are often annotated in two different entries if their sequences differ significantly.
Note: Based on a naturally occurring readthrough transcript which produces a FPGT-TNNI3K fusion protein.
Length:843
Mass (Da):94,517
GO
Isoform 5 (identifier: O14772-2) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     1-13: Missing.
     150-403: Missing.

Note: No experimental confirmation available.
Show »
Length:340
Mass (Da):37,631
Checksum:i804504F161653FD2
GO
Isoform 6 (identifier: O14772-3) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     1-13: Missing.
     128-607: GGYSQRLPNA...LEISLKSSLM → VSFQIYQNAL...KTALLVVLTS

Note: No experimental confirmation available.
Show »
Length:169
Mass (Da):19,170
Checksum:iE8D68424A3C4D277
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There are 4 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
H0YDF0H0YDF0_HUMAN
Fucose-1-phosphate guanylyltransfer...
FPGT
174Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
E9PK10E9PK10_HUMAN
Fucose-1-phosphate guanylyltransfer...
FPGT
101Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
E9PMK0E9PMK0_HUMAN
Fucose-1-phosphate guanylyltransfer...
FPGT
128Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
E9PMM4E9PMM4_HUMAN
Fucose-1-phosphate guanylyltransfer...
FPGT
137Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

<p>This subsection of the ‘Sequence’ section reports difference(s) between the protein sequence shown in the UniProtKB entry and other available protein sequences derived from the same gene.<p><a href='/help/sequence_caution' target='_top'>More...</a></p>Sequence cautioni

The sequence AAC73005 differs from that shown. Reason: Erroneous initiation. Translation N-terminally extended.Curated
The sequence AAC82511 differs from that shown. Reason: Erroneous gene model prediction.Curated
The sequence AAH32308 differs from that shown. Reason: Erroneous initiation. Translation N-terminally extended.Curated
The sequence BAG65299 differs from that shown. Reason: Erroneous translation. Wrong choice of CDS.Curated

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti57A → T in BAG61434 (PubMed:14702039).Curated1
Sequence conflicti335N → H in AAC73005 (PubMed:9804772).Curated1
Sequence conflicti562K → R in BAG61434 (PubMed:14702039).Curated1

Natural variant

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section describes natural variant(s) of the protein sequence.<p><a href='/help/variant' target='_top'>More...</a></p>Natural variantiVAR_061650461P → L. Corresponds to variant dbSNP:rs55882158Ensembl.1

Alternative sequence

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section describes the sequence of naturally occurring alternative protein isoform(s). The changes in the amino acid sequence may be due to alternative splicing, alternative promoter usage, alternative initiation, or ribosomal frameshifting.<p><a href='/help/var_seq' target='_top'>More...</a></p>Alternative sequenceiVSP_0595411 – 13Missing in isoform 5 and isoform 6. CuratedAdd BLAST13
Alternative sequenceiVSP_059542128 – 607GGYSQ…KSSLM → VSFQIYQNALAKHPVSFKAY WIQDVLWHLAQLWSIPDWGL MFQLGKTALLVVLTS in isoform 6. CuratedAdd BLAST480
Alternative sequenceiVSP_059543150 – 403Missing in isoform 5. CuratedAdd BLAST254

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AF017445 mRNA Translation: AAC73005.1 Different initiation.
AF017446 Genomic DNA Translation: AAC82511.1 Sequence problems.
AK299468 mRNA Translation: BAG61434.1
AK304490 mRNA Translation: BAG65299.1 Sequence problems.
AC098692 Genomic DNA No translation available.
BC032308 mRNA Translation: AAH32308.1 Different initiation.

The Consensus CDS (CCDS) project

More...
CCDSi
CCDS663.2 [O14772-1]

NCBI Reference Sequences

More...
RefSeqi
NP_001186257.2, NM_001199328.2
NP_001186258.2, NM_001199329.2
NP_003829.3, NM_003838.4 [O14772-1]

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENST00000370894; ENSP00000359931; ENSG00000254685 [O14772-3]
ENST00000370898; ENSP00000359935; ENSG00000254685 [O14772-1]
ENST00000534056; ENSP00000432819; ENSG00000254685 [O14772-2]

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
8790

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
hsa:8790

UCSC genome browser

More...
UCSCi
uc057hpq.1 human [O14772-1]

Keywords - Coding sequence diversityi

Alternative splicing, Polymorphism

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF017445 mRNA Translation: AAC73005.1 Different initiation.
AF017446 Genomic DNA Translation: AAC82511.1 Sequence problems.
AK299468 mRNA Translation: BAG61434.1
AK304490 mRNA Translation: BAG65299.1 Sequence problems.
AC098692 Genomic DNA No translation available.
BC032308 mRNA Translation: AAH32308.1 Different initiation.
CCDSiCCDS663.2 [O14772-1]
RefSeqiNP_001186257.2, NM_001199328.2
NP_001186258.2, NM_001199329.2
NP_003829.3, NM_003838.4 [O14772-1]

3D structure databases

SMRiO14772
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi114318, 1 interactor
STRINGi9606.ENSP00000359935

PTM databases

iPTMnetiO14772
PhosphoSitePlusiO14772

Polymorphism and mutation databases

BioMutaiFPGT

Proteomic databases

EPDiO14772
jPOSTiO14772
PaxDbiO14772
PeptideAtlasiO14772
PRIDEiO14772
ProteomicsDBi48223

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000370894; ENSP00000359931; ENSG00000254685 [O14772-3]
ENST00000370898; ENSP00000359935; ENSG00000254685 [O14772-1]
ENST00000534056; ENSP00000432819; ENSG00000254685 [O14772-2]
GeneIDi8790
KEGGihsa:8790
UCSCiuc057hpq.1 human [O14772-1]

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
8790
DisGeNETi8790

GeneCards: human genes, protein and diseases

More...
GeneCardsi
FPGT
HGNCiHGNC:3825 FPGT
HPAiHPA072331
MIMi603609 gene
neXtProtiNX_O14772
OpenTargetsiENSG00000254685
PharmGKBiPA28243

GenAtlas: human gene database

More...
GenAtlasi
Search...

Phylogenomic databases

eggNOGiENOG410IE28 Eukaryota
ENOG410XT7S LUCA
GeneTreeiENSGT00780000122095
HOGENOMiHOG000067964
InParanoidiO14772
KOiK00976
OMAiDMIAYRE
OrthoDBi173077at2759
PhylomeDBiO14772
TreeFamiTF328750

Enzyme and pathway databases

BRENDAi2.7.7.30 2681
ReactomeiR-HSA-6787639 GDP-fucose biosynthesis

Miscellaneous databases

The Gene Wiki collection of pages on human genes and proteins

More...
GeneWikii
FPGT

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

More...
GenomeRNAii
8790

The Stanford Online Universal Resource for Clones and ESTs

More...
SOURCEi
Search...

Gene expression databases

BgeeiENSG00000254685 Expressed in 197 organ(s), highest expression level in sigmoid colon
ExpressionAtlasiO14772 baseline and differential
GenevisibleiO14772 HS

Family and domain databases

InterProiView protein in InterPro
IPR012887 Fucokinase
IPR012120 Fucose-1-phosphate_GuaTrfase
IPR011004 Trimer_LpxA-like_sf
PfamiView protein in Pfam
PF07959 Fucokinase, 1 hit
PIRSFiPIRSF036640 FPGT, 1 hit
SUPFAMiSSF51161 SSF51161, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiFPGT_HUMAN
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: O14772
Secondary accession number(s): A0A0A0MRP2
, A6NMH3, B4DRX2, B4E2Y7, E9PNQ2, Q8N5J7
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: January 10, 2003
Last sequence update: April 25, 2018
Last modified: May 8, 2019
This is version 141 of the entry and version 3 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Human chromosome 1
    Human chromosome 1: entries, gene names and cross-references to MIM
  2. Human entries with polymorphisms or disease mutations
    List of human entries with polymorphisms or disease mutations
  3. Human polymorphisms and disease mutations
    Index of human polymorphisms and disease mutations
  4. MIM cross-references
    Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.

Do not show this banner again