Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
The new UniProt website is here! Take me to UniProt BETA

UniProtKB - O14683 (P5I11_HUMAN)

Entry version 125 (25 May 2022)
Sequence version 2 (15 Jun 2010)
Previous versions | rss
Add a publicationFeedback
Protein

Tumor protein p53-inducible protein 11

Gene

TP53I11

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score:

Annotation score:3 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Biological processi

Complete GO annotation on QuickGO ...

Enzyme and pathway databases

Pathway Commons web resource for biological pathway data

More...PathwayCommonsi		O14683

SignaLink: a signaling pathway resource with multi-layered regulatory networks

More...SignaLinki		O14683

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Tumor protein p53-inducible protein 11
Alternative name(s):
p53-induced gene 11 protein
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:TP53I11
Synonyms:PIG11
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 11

Organism-specific databases

Human Gene Nomenclature Database

More...HGNCi		HGNC:16842, TP53I11

Online Mendelian Inheritance in Man (OMIM)

More...MIMi		617867, gene

neXtProt; the human protein knowledge platform

More...neXtProti		NX_O14683

Eukaryotic Pathogen, Vector and Host Database Resources

More...VEuPathDBi		HostDB:ENSG00000175274

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/subcellular%5Flocation%5Fsection">'Subcellular location'</a> section describes the subcellular compartment where each non-membrane region of a membrane-spanning protein is found.<p><a href='/help/topo_dom' target='_top'>More...</a></p>Topological domaini1 – 63CytoplasmicSequence analysisAdd BLAST63
<p>This subsection of the <a href="http://www.uniprot.org/help/subcellular%5Flocation%5Fsection">'Subcellular location'</a> section describes the extent of a membrane-spanning region of the protein. It denotes the presence of both alpha-helical transmembrane regions and the membrane spanning regions of beta-barrel transmembrane proteins.<p><a href='/help/transmem' target='_top'>More...</a></p>Transmembranei64 – 84HelicalSequence analysisAdd BLAST21
Topological domaini85 – 108ExtracellularSequence analysisAdd BLAST24
Transmembranei109 – 129HelicalSequence analysisAdd BLAST21
Topological domaini130CytoplasmicSequence analysis1
Transmembranei131 – 151HelicalSequence analysisAdd BLAST21
Topological domaini152 – 155ExtracellularSequence analysis4
Transmembranei156 – 176HelicalSequence analysisAdd BLAST21
Topological domaini177 – 189CytoplasmicSequence analysisAdd BLAST13

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Cellular componenti

Membrane

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

DisGeNET

More...DisGeNETi		9537

Open Targets

More...OpenTargetsi		ENSG00000175274

The Pharmacogenetics and Pharmacogenomics Knowledge Base

More...PharmGKBi		PA134967898

Miscellaneous databases

Pharos NIH Druggable Genome Knowledgebase

More...Pharosi		O14683, Tbio

Genetic variation databases

BioMuta curated single-nucleotide variation and disease association database

More...BioMutai		TP53I11

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00000581421 – 189Tumor protein p53-inducible protein 11Add BLAST189

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section specifies the position and type of each modified residue excluding <a href="http://www.uniprot.org/manual/lipid">lipids</a>, <a href="http://www.uniprot.org/manual/carbohyd">glycans</a> and <a href="http://www.uniprot.org/manual/crosslnk">protein cross-links</a>.<p><a href='/help/mod_res' target='_top'>More...</a></p>Modified residuei14PhosphoserineCombined sources1

Keywords - PTMi

Phosphoprotein

Proteomic databases

Encyclopedia of Proteome Dynamics

More...EPDi		O14683

jPOST - Japan Proteome Standard Repository/Database

More...jPOSTi		O14683

MassIVE - Mass Spectrometry Interactive Virtual Environment

More...MassIVEi		O14683

MaxQB - The MaxQuant DataBase

More...MaxQBi		O14683

PaxDb, a database of protein abundance averages across all three domains of life

More...PaxDbi		O14683

PeptideAtlas

More...PeptideAtlasi		O14683

PRoteomics IDEntifications database

More...PRIDEi		O14683

ProteomicsDB: a multi-organism proteome resource

More...ProteomicsDBi		48166

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...iPTMneti		O14683

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...PhosphoSitePlusi		O14683

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

<p>This subsection of the 'Expression' section reports the experimentally proven effects of inducers and repressors (usually chemical compounds or environmental factors) on the level of protein (or mRNA) expression (up-regulation, down-regulation, constitutive expression).<p><a href='/help/induction' target='_top'>More...</a></p>Inductioni

By p53/TP53.1 Publication

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...Bgeei		ENSG00000175274, Expressed in cortical plate and 197 other tissues

ExpressionAtlas, Differential and Baseline Expression

More...ExpressionAtlasi		O14683, baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...Genevisiblei		O14683, HS

Organism-specific databases

Human Protein Atlas

More...HPAi		ENSG00000175274, Low tissue specificity

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGRID)

More...BioGRIDi		114913, 36 interactors

Protein interaction database and analysis system

More...IntActi		O14683, 10 interactors

Molecular INTeraction database

More...MINTi		O14683

STRING: functional protein association networks

More...STRINGi		9606.ENSP00000436152

Miscellaneous databases

RNAct, Protein-RNA interaction predictions for model organisms.

More...RNActi		O14683, protein

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

AlphaFold Protein Structure Database

More...AlphaFoldDBi		O14683

Database of comparative protein structure models

More...ModBasei		Search...

SWISS-MODEL Interactive Workspace

More...SWISS-MODEL-Workspacei		Submit a new modelling project...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...eggNOGi		ENOG502QQ2K, Eukaryota

Ensembl GeneTree

More...GeneTreei		ENSGT00390000017249

InParanoid: Eukaryotic Ortholog Groups

More...InParanoidi		O14683

Identification of Orthologs from Complete Genome Data

More...OMAi		VQFVVVT

Database of Orthologous Groups

More...OrthoDBi		1573043at2759

Database for complete collections of gene phylogenies

More...PhylomeDBi		O14683

TreeFam database of animal gene trees

More...TreeFami		TF321310

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...InterProi		View protein in InterPro
IPR028266, TP53I11

The PANTHER Classification System

More...PANTHERi		PTHR31584, PTHR31584, 1 hit

Pfam protein domain database

More...Pfami		View protein in Pfam
PF14936, p53-inducible11, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequence (1+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry has 1 described isoform and 12 potential isoforms that are computationally mapped.Show allAlign All

O14683-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MAAKQPPPLM KKHSQTDLVS RLKTRKILGV GGEDDDGEVH RSKISQVLGN 
        60         70         80         90        100
EIKFTIREPL GLRVWQFVSA VLFSGIAIMA LAFPDQLYDA VFDGAQVTSK 
       110        120        130        140        150
TPIRLYGGAL LSISLIMWNA LYTAEKVIIR WTLLTEACYF GVQFLVVTAT 
       160        170        180 
LAETGLMSLG ILLLLVSRLL FVVISIYYYY QVGRRPKKA
Length:189
Mass (Da):21,054
Last modified:June 15, 2010 - v2
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i5E858F5872FE3171
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There are 12 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
E9PPM1E9PPM1_HUMAN
Tumor protein p53-inducible protein...
TP53I11
236Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
E9PIN5E9PIN5_HUMAN
Tumor protein p53-inducible protein...
TP53I11
123Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
U3KQ32U3KQ32_HUMAN
Tumor protein p53-inducible protein...
TP53I11
154Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
E9PKZ4E9PKZ4_HUMAN
Tumor protein p53-inducible protein...
TP53I11
158Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
E9PQ46E9PQ46_HUMAN
Tumor protein p53-inducible protein...
TP53I11
98Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
E9PMW4E9PMW4_HUMAN
Tumor protein p53-inducible protein...
TP53I11
93Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
E9PMY0E9PMY0_HUMAN
Tumor protein p53-inducible protein...
TP53I11
91Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
E9PN66E9PN66_HUMAN
Tumor protein p53-inducible protein...
TP53I11
62Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
E9PKN9E9PKN9_HUMAN
Tumor protein p53-inducible protein...
TP53I11
73Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
E9PS55E9PS55_HUMAN
Tumor protein p53-inducible protein...
TP53I11
79Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
There are more potential isoformsShow all

<p>This subsection of the 'Sequence' section reports difference(s) between the protein sequence shown in the UniProtKB entry and other available protein sequences derived from the same gene.<p><a href='/help/sequence_caution' target='_top'>More...</a></p>Sequence cautioni

The sequence AAC39533 differs from that shown. Localized in an untranslated region: wrong choice of CDS.Curated

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...EMBLi

GenBank nucleotide sequence database

More...GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...DDBJi
Links Updated
AF010315 mRNA Translation: AAC39533.1 Sequence problems.
AK292837 mRNA Translation: BAF85526.1
AC068858 Genomic DNA No translation available.
AC092733 Genomic DNA No translation available.
CH471064 Genomic DNA Translation: EAW68052.1
CH471064 Genomic DNA Translation: EAW68053.1
CH471064 Genomic DNA Translation: EAW68055.1
CH471064 Genomic DNA Translation: EAW68057.1
BC045666 mRNA Translation: AAH45666.1

The Consensus CDS (CCDS) project

More...CCDSi		CCDS7911.1

NCBI Reference Sequences

More...RefSeqi		NP_001245249.1, NM_001258320.1
NP_001245250.1, NM_001258321.1
NP_001245251.1, NM_001258322.1
NP_001245252.1, NM_001258323.2
NP_001245253.1, NM_001258324.1
NP_001305313.1, NM_001318384.1
NP_001305314.1, NM_001318385.1
NP_001305315.1, NM_001318386.1
NP_006025.2, NM_006034.4
XP_005253284.1, XM_005253227.4
XP_011518777.1, XM_011520475.2
XP_011518778.1, XM_011520476.2
XP_011518779.1, XM_011520477.2
XP_011518780.1, XM_011520478.2
XP_016874069.1, XM_017018580.1
XP_016874070.1, XM_017018581.1

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...Ensembli		ENST00000308212.9; ENSP00000309532.5; ENSG00000175274.19
ENST00000395648.7; ENSP00000379009.3; ENSG00000175274.19
ENST00000525680.6; ENSP00000433474.1; ENSG00000175274.19
ENST00000533940.5; ENSP00000436152.1; ENSG00000175274.19
ENST00000616990.4; ENSP00000481456.1; ENSG00000175274.19

Database of genes from NCBI RefSeq genomes

More...GeneIDi		9537

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...KEGGi		hsa:9537

Matched Annotation from NCBI and EMBL-EBI (MANE) - Phase one

More...MANE-Selecti		ENST00000525680.6; ENSP00000433474.1; NM_006034.5; NP_006025.2

UCSC genome browser

More...UCSCi		uc001myi.5, human

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF010315 mRNA Translation: AAC39533.1 Sequence problems.
AK292837 mRNA Translation: BAF85526.1
AC068858 Genomic DNA No translation available.
AC092733 Genomic DNA No translation available.
CH471064 Genomic DNA Translation: EAW68052.1
CH471064 Genomic DNA Translation: EAW68053.1
CH471064 Genomic DNA Translation: EAW68055.1
CH471064 Genomic DNA Translation: EAW68057.1
BC045666 mRNA Translation: AAH45666.1
CCDSiCCDS7911.1
RefSeqiNP_001245249.1, NM_001258320.1
NP_001245250.1, NM_001258321.1
NP_001245251.1, NM_001258322.1
NP_001245252.1, NM_001258323.2
NP_001245253.1, NM_001258324.1
NP_001305313.1, NM_001318384.1
NP_001305314.1, NM_001318385.1
NP_001305315.1, NM_001318386.1
NP_006025.2, NM_006034.4
XP_005253284.1, XM_005253227.4
XP_011518777.1, XM_011520475.2
XP_011518778.1, XM_011520476.2
XP_011518779.1, XM_011520477.2
XP_011518780.1, XM_011520478.2
XP_016874069.1, XM_017018580.1
XP_016874070.1, XM_017018581.1

3D structure databases

AlphaFoldDBiO14683
ModBaseiSearch...
SWISS-MODEL-WorkspaceiSubmit a new modelling project...

Protein-protein interaction databases

BioGRIDi114913, 36 interactors
IntActiO14683, 10 interactors
MINTiO14683
STRINGi9606.ENSP00000436152

PTM databases

iPTMnetiO14683
PhosphoSitePlusiO14683

Genetic variation databases

BioMutaiTP53I11

Proteomic databases

EPDiO14683
jPOSTiO14683
MassIVEiO14683
MaxQBiO14683
PaxDbiO14683
PeptideAtlasiO14683
PRIDEiO14683
ProteomicsDBi48166

Protocols and materials databases

Antibodypedia a portal for validated antibodies

More...Antibodypediai		26149, 185 antibodies from 27 providers

The DNASU plasmid repository

More...DNASUi		9537

Genome annotation databases

EnsembliENST00000308212.9; ENSP00000309532.5; ENSG00000175274.19
ENST00000395648.7; ENSP00000379009.3; ENSG00000175274.19
ENST00000525680.6; ENSP00000433474.1; ENSG00000175274.19
ENST00000533940.5; ENSP00000436152.1; ENSG00000175274.19
ENST00000616990.4; ENSP00000481456.1; ENSG00000175274.19
GeneIDi9537
KEGGihsa:9537
MANE-SelectiENST00000525680.6; ENSP00000433474.1; NM_006034.5; NP_006025.2
UCSCiuc001myi.5, human

Organism-specific databases

Comparative Toxicogenomics Database

More...CTDi		9537
DisGeNETi9537

GeneCards: human genes, protein and diseases

More...GeneCardsi		TP53I11
HGNCiHGNC:16842, TP53I11
HPAiENSG00000175274, Low tissue specificity
MIMi617867, gene
neXtProtiNX_O14683
OpenTargetsiENSG00000175274
PharmGKBiPA134967898
VEuPathDBiHostDB:ENSG00000175274

GenAtlas: human gene database

More...GenAtlasi		Search...

Phylogenomic databases

eggNOGiENOG502QQ2K, Eukaryota
GeneTreeiENSGT00390000017249
InParanoidiO14683
OMAiVQFVVVT
OrthoDBi1573043at2759
PhylomeDBiO14683
TreeFamiTF321310

Enzyme and pathway databases

PathwayCommonsiO14683
SignaLinkiO14683

Miscellaneous databases

BioGRID ORCS database of CRISPR phenotype screens

More...BioGRID-ORCSi		9537, 16 hits in 1075 CRISPR screens

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

More...ChiTaRSi		TP53I11, human

The Gene Wiki collection of pages on human genes and proteins

More...GeneWikii		TP53I11

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

More...GenomeRNAii		9537
PharosiO14683, Tbio

Protein Ontology

More...PROi		PR:O14683
RNActiO14683, protein

The Stanford Online Universal Resource for Clones and ESTs

More...SOURCEi		Search...

Gene expression databases

BgeeiENSG00000175274, Expressed in cortical plate and 197 other tissues
ExpressionAtlasiO14683, baseline and differential
GenevisibleiO14683, HS

Family and domain databases

InterProiView protein in InterPro
IPR028266, TP53I11
PANTHERiPTHR31584, PTHR31584, 1 hit
PfamiView protein in Pfam
PF14936, p53-inducible11, 1 hit

MobiDB: a database of protein disorder and mobility annotations

More...MobiDBi		Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiP5I11_HUMAN
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: O14683
Secondary accession number(s): Q3ZCS0
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: May 30, 2000
Last sequence update: June 15, 2010
Last modified: May 25, 2022
This is version 125 of the entry and version 2 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteome

Documents

  1. Human chromosome 11
    Human chromosome 11: entries, gene names and cross-references to MIM
  2. MIM cross-references
    Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.

Do not show this banner again