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UniProtKB - O14645 (IDLC_HUMAN)

Entry version 136 (13 Feb 2019)
Sequence version 2 (27 Sep 2005)
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Protein

Axonemal dynein light intermediate polypeptide 1

Gene

DNALI1

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

May play a dynamic role in flagellar motility.

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

  • dynein heavy chain binding Source: GO_Central
  • motor activity Source: UniProtKB-KW
View the complete GO annotation on QuickGO ...

GO - Biological processi

View the complete GO annotation on QuickGO ...

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionMotor protein

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Axonemal dynein light intermediate polypeptide 1
Alternative name(s):
Inner dynein arm light chain, axonemal
hp28
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:DNALI1
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 1

Organism-specific databases

Eukaryotic Pathogen Database Resources

More...EuPathDBi		HostDB:ENSG00000163879.10

Human Gene Nomenclature Database

More...HGNCi		HGNC:14353 DNALI1

Online Mendelian Inheritance in Man (OMIM)

More...MIMi		602135 gene

neXtProt; the human protein knowledge platform

More...neXtProti		NX_O14645

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Cell projection, Dynein

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

DisGeNET

More...DisGeNETi		7802

The Pharmacogenetics and Pharmacogenomics Knowledge Base

More...PharmGKBi		PA38381

Polymorphism and mutation databases

BioMuta curated single-nucleotide variation and disease association database

More...BioMutai		DNALI1

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00001146751 – 258Axonemal dynein light intermediate polypeptide 1Add BLAST258

Proteomic databases

Encyclopedia of Proteome Dynamics

More...EPDi		O14645

PaxDb, a database of protein abundance averages across all three domains of life

More...PaxDbi		O14645

PeptideAtlas

More...PeptideAtlasi		O14645

PRoteomics IDEntifications database

More...PRIDEi		O14645

ProteomicsDB human proteome resource

More...ProteomicsDBi		48141

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...iPTMneti		O14645

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...PhosphoSitePlusi		O14645

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

<p>This subsection of the ‘Expression’ section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms. By default, the information is derived from experiments at the mRNA level, unless specified ‘at protein level’. <br></br>Examples: <a href="http://www.uniprot.org/uniprot/P92958#expression">P92958</a>, <a href="http://www.uniprot.org/uniprot/Q8TDN4#expression">Q8TDN4</a>, <a href="http://www.uniprot.org/uniprot/O14734#expression">O14734</a><p><a href='/help/tissue_specificity' target='_top'>More...</a></p>Tissue specificityi

Expressed in many tissues. A smaller 0.9 kb and a larger 2.5 kb transcripts were detected at the highest level in the testis, at medium levels in the prostate, heart, liver, lung and pancreas, at low levels in the ovary, skeletal muscle and small intestine. Not detected in spleen, colon epithelium, thymus or peripheral blood leukocytes. The 0.9 kb transcript is expressed at a 20-fold higher level than the 2.5 kb transcript in the testis.

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...Bgeei		ENSG00000163879 Expressed in 150 organ(s), highest expression level in testis

Genevisible search portal to normalized and curated expression data from Genevestigator

More...Genevisiblei		O14645 HS

Organism-specific databases

Human Protein Atlas

More...HPAi		HPA028305

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the '<a href="http://www.uniprot.org/help/interaction_section%27">Interaction</a> section provides information about binary protein-protein interactions. The data presented in this section are a quality-filtered subset of binary interactions automatically derived from the <a href="http://www.ebi.ac.uk/intact/">IntAct database</a>. It is updated on a monthly basis. Each binary interaction is displayed on a separate line.<p><a href='/help/binary_interactions' target='_top'>More...</a></p>Binary interactionsi

GO - Molecular functioni

View the complete GO annotation on QuickGO ...

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGrid)

More...BioGridi		113577, 16 interactors

Protein interaction database and analysis system

More...IntActi		O14645, 18 interactors

Molecular INTeraction database

More...MINTi		O14645

STRING: functional protein association networks

More...STRINGi		9606.ENSP00000296218

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

Protein Model Portal of the PSI-Nature Structural Biology Knowledgebase

More...ProteinModelPortali		O14645

Database of comparative protein structure models

More...ModBasei		Search...

MobiDB: a database of protein disorder and mobility annotations

More...MobiDBi		Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and domains’ section denotes the positions of regions of coiled coil within the protein.<p><a href='/help/coiled' target='_top'>More...</a></p>Coiled coili176 – 255Sequence analysisAdd BLAST80

<p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the inner dynein arm light chain family.Curated

Keywords - Domaini

Coiled coil

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...eggNOGi		KOG4001 Eukaryota
ENOG410XP66 LUCA

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...HOGENOMi		HOG000090301

The HOVERGEN Database of Homologous Vertebrate Genes

More...HOVERGENi		HBG019035

InParanoid: Eukaryotic Ortholog Groups

More...InParanoidi		O14645

KEGG Orthology (KO)

More...KOi		K10410

Database of Orthologous Groups

More...OrthoDBi		1375694at2759

Database for complete collections of gene phylogenies

More...PhylomeDBi		O14645

TreeFam database of animal gene trees

More...TreeFami		TF314891

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...InterProi		View protein in InterPro
IPR019347 Axonemal_dynein_light_chain

The PANTHER Classification System

More...PANTHERi		PTHR13183 PTHR13183, 1 hit

Pfam protein domain database

More...Pfami		View protein in Pfam
PF10211 Ax_dynein_light, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>.<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequences (2)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry describes 2 <p>This subsection of the ‘Sequence’ section lists the alternative protein sequences (isoforms) that can be generated from the same gene by a single or by the combination of up to four biological events (alternative promoter usage, alternative splicing, alternative initiation and ribosomal frameshifting). Additionally, this section gives relevant information on each alternative protein isoform.<p><a href='/help/alternative_products' target='_top'>More...</a></p> isoformsi produced by alternative splicing. AlignAdd to basket
Isoform 1 (identifier: O14645-1) [UniParc]FASTAAdd to basket

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide
        10         20         30         40         50
MIPPADSLLK YDTPVLVSRN TEKRSPKARL LKVSPQQPGP SGSAPQPPKT 
        60         70         80         90        100
KLPSTPCVPD PTKQAEEILN AILPPREWVE DTQLWIQQVS STPSTRMDVV 
       110        120        130        140        150
HLQEQLDLKL QQRQARETGI CPVRRELYSQ CFDELIREVT INCAERGLLL 
       160        170        180        190        200
LRVRDEIRMT IAAYQTLYES SVAFGMRKAL QAEQGKSDME RKIAELETEK 
       210        220        230        240        250
RDLERQVNEQ KAKCEATEKR ESERRQVEEK KHNEEIQFLK RTNQQLKAQL 

EGIIAPKK
Length:258
Mass (Da):29,662
Last modified:September 27, 2005 - v2
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i5E95F15FE4476BF7
GO
Isoform 2 (identifier: O14645-2) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     1-6: MIPPAD → MPYYPQ
     7-132: Missing.

Note: No experimental confirmation available.
Show »
Length:132
Mass (Da):15,583
Checksum:iD0AD5D94C2965156
GO

<p>This subsection of the ‘Sequence’ section reports difference(s) between the protein sequence shown in the UniProtKB entry and other available protein sequences derived from the same gene.<p><a href='/help/sequence_caution' target='_top'>More...</a></p>Sequence cautioni

The sequence AAB69193 differs from that shown. Reason: Frameshift at positions 7, 28, 94, 125, 139 and 153.Curated
The sequence CAI46082 differs from that shown. Reason: Erroneous initiation. Translation N-terminally extended.Curated

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti54S → P in CAI46082 (PubMed:17974005).Curated1
Sequence conflicti76R → K in BAF83191 (PubMed:14702039).Curated1
Sequence conflicti152R → Q in AAB69193 (PubMed:9284741).Curated1

Natural variant

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section describes natural variant(s) of the protein sequence.<p><a href='/help/variant' target='_top'>More...</a></p>Natural variantiVAR_01447365A → V. Corresponds to variant dbSNP:rs11749Ensembl.1
Natural variantiVAR_035701120I → M in a colorectal cancer sample; somatic mutation. 1 Publication1

Alternative sequence

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section describes the sequence of naturally occurring alternative protein isoform(s). The changes in the amino acid sequence may be due to alternative splicing, alternative promoter usage, alternative initiation, or ribosomal frameshifting.<p><a href='/help/var_seq' target='_top'>More...</a></p>Alternative sequenceiVSP_0569651 – 6MIPPAD → MPYYPQ in isoform 2. 1 Publication6
Alternative sequenceiVSP_0569667 – 132Missing in isoform 2. 1 PublicationAdd BLAST126

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...EMBLi

GenBank nucleotide sequence database

More...GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...DDBJi
Links Updated
AF006386 mRNA Translation: AAB69193.1 Frameshift.
AK295199 mRNA Translation: BAG58198.1
AK290502 mRNA Translation: BAF83191.1
BX647913 mRNA Translation: CAI46082.1 Different initiation.
AL034379 Genomic DNA No translation available.
BC039074 mRNA Translation: AAH39074.1
BC046117 mRNA Translation: AAH46117.1

The Consensus CDS (CCDS) project

More...CCDSi		CCDS420.1 [O14645-1]

NCBI Reference Sequences

More...RefSeqi		NP_003453.2, NM_003462.3 [O14645-1]
XP_005271229.1, XM_005271172.2 [O14645-2]

UniGene gene-oriented nucleotide sequence clusters

More...UniGenei		Hs.406050

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...Ensembli		ENST00000296218; ENSP00000296218; ENSG00000163879

Database of genes from NCBI RefSeq genomes

More...GeneIDi		7802

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...KEGGi		hsa:7802

UCSC genome browser

More...UCSCi		uc001cbj.3 human [O14645-1]

Keywords - Coding sequence diversityi

Alternative splicing, Polymorphism

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF006386 mRNA Translation: AAB69193.1 Frameshift.
AK295199 mRNA Translation: BAG58198.1
AK290502 mRNA Translation: BAF83191.1
BX647913 mRNA Translation: CAI46082.1 Different initiation.
AL034379 Genomic DNA No translation available.
BC039074 mRNA Translation: AAH39074.1
BC046117 mRNA Translation: AAH46117.1
CCDSiCCDS420.1 [O14645-1]
RefSeqiNP_003453.2, NM_003462.3 [O14645-1]
XP_005271229.1, XM_005271172.2 [O14645-2]
UniGeneiHs.406050

3D structure databases

ProteinModelPortaliO14645
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi113577, 16 interactors
IntActiO14645, 18 interactors
MINTiO14645
STRINGi9606.ENSP00000296218

PTM databases

iPTMnetiO14645
PhosphoSitePlusiO14645

Polymorphism and mutation databases

BioMutaiDNALI1

Proteomic databases

EPDiO14645
PaxDbiO14645
PeptideAtlasiO14645
PRIDEiO14645
ProteomicsDBi48141

Protocols and materials databases

The DNASU plasmid repository

More...DNASUi		7802
Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000296218; ENSP00000296218; ENSG00000163879
GeneIDi7802
KEGGihsa:7802
UCSCiuc001cbj.3 human [O14645-1]

Organism-specific databases

Comparative Toxicogenomics Database

More...CTDi		7802
DisGeNETi7802
EuPathDBiHostDB:ENSG00000163879.10

GeneCards: human genes, protein and diseases

More...GeneCardsi		DNALI1

H-Invitational Database, human transcriptome db

More...H-InvDBi		HIX0023523
HGNCiHGNC:14353 DNALI1
HPAiHPA028305
MIMi602135 gene
neXtProtiNX_O14645
PharmGKBiPA38381

GenAtlas: human gene database

More...GenAtlasi		Search...

Phylogenomic databases

eggNOGiKOG4001 Eukaryota
ENOG410XP66 LUCA
HOGENOMiHOG000090301
HOVERGENiHBG019035
InParanoidiO14645
KOiK10410
OrthoDBi1375694at2759
PhylomeDBiO14645
TreeFamiTF314891

Miscellaneous databases

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

More...ChiTaRSi		DNALI1 human

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

More...GenomeRNAii		7802

Protein Ontology

More...PROi		PR:O14645

The Stanford Online Universal Resource for Clones and ESTs

More...SOURCEi		Search...

Gene expression databases

BgeeiENSG00000163879 Expressed in 150 organ(s), highest expression level in testis
GenevisibleiO14645 HS

Family and domain databases

InterProiView protein in InterPro
IPR019347 Axonemal_dynein_light_chain
PANTHERiPTHR13183 PTHR13183, 1 hit
PfamiView protein in Pfam
PF10211 Ax_dynein_light, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...ProtoNeti		Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiIDLC_HUMAN
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: O14645
Secondary accession number(s): A8K387
, B4DHN6, Q05BL9, Q5HYE2, Q5TGH0, Q7L0I5
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: June 20, 2001
Last sequence update: September 27, 2005
Last modified: February 13, 2019
This is version 136 of the entry and version 2 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
  2. MIM cross-references
    Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
  3. Human chromosome 1
    Human chromosome 1: entries, gene names and cross-references to MIM
  4. Human entries with polymorphisms or disease mutations
    List of human entries with polymorphisms or disease mutations
  5. Human polymorphisms and disease mutations
    Index of human polymorphisms and disease mutations
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