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UniProtKB - O14522 (PTPRT_HUMAN)

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Protein

Receptor-type tyrosine-protein phosphatase T

Gene

PTPRT

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

May be involved in both signal transduction and cellular adhesion in the CNS.

Catalytic activityi

Protein tyrosine phosphate + H2O = protein tyrosine + phosphate.PROSITE-ProRule annotation

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Binding sitei1052SubstrateBy similarity1
Active sitei1084Phosphocysteine intermediateBy similarity1
Binding sitei1128SubstrateBy similarity1
Active sitei1378Phosphocysteine intermediateBy similarity1

GO - Molecular functioni

  • alpha-catenin binding Source: UniProtKB
  • beta-catenin binding Source: UniProtKB
  • cadherin binding Source: UniProtKB
  • delta-catenin binding Source: UniProtKB
  • gamma-catenin binding Source: UniProtKB
  • protein tyrosine phosphatase activity Source: UniProtKB
View the complete GO annotation on QuickGO ...

GO - Biological processi

  • cell adhesion Source: UniProtKB
  • homophilic cell adhesion via plasma membrane adhesion molecules Source: UniProtKB
  • protein dephosphorylation Source: UniProtKB
  • signal transduction Source: UniProtKB
  • transmembrane receptor protein tyrosine kinase signaling pathway Source: UniProtKB
View the complete GO annotation on QuickGO ...

Keywordsi

Molecular functionHydrolase, Protein phosphatase, Receptor

Enzyme and pathway databases

BRENDAi3.1.3.48 2681
SignaLinkiO14522

Names & Taxonomyi

Protein namesi
Recommended name:
Receptor-type tyrosine-protein phosphatase T (EC:3.1.3.48)
Short name:
R-PTP-T
Alternative name(s):
Receptor-type tyrosine-protein phosphatase rho
Short name:
RPTP-rho
Gene namesi
Name:PTPRT
Synonyms:KIAA0283
OrganismiHomo sapiens (Human)
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo
Proteomesi
  • UP000005640 Componenti: Chromosome 20

Organism-specific databases

EuPathDBiHostDB:ENSG00000196090.12
HGNCiHGNC:9682 PTPRT
MIMi608712 gene
neXtProtiNX_O14522

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Topological domaini26 – 747ExtracellularSequence analysisAdd BLAST722
Transmembranei748 – 768HelicalSequence analysisAdd BLAST21
Topological domaini769 – 1441CytoplasmicSequence analysisAdd BLAST673

Keywords - Cellular componenti

Membrane

Pathology & Biotechi

Organism-specific databases

DisGeNETi11122
OpenTargetsiENSG00000196090
PharmGKBiPA34027

Polymorphism and mutation databases

BioMutaiPTPRT

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 25Sequence analysisAdd BLAST25
ChainiPRO_000002546326 – 1441Receptor-type tyrosine-protein phosphatase TAdd BLAST1416

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Glycosylationi78N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi98N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi137N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi208N-linked (GlcNAc...) asparagineSequence analysis1
Disulfide bondi213 ↔ 267PROSITE-ProRule annotation
Glycosylationi421N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi510N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi547N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi601N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi654N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi684N-linked (GlcNAc...) asparagineSequence analysis1
Modified residuei1208PhosphoserineBy similarity1

Keywords - PTMi

Disulfide bond, Glycoprotein, Phosphoprotein

Proteomic databases

EPDiO14522
MaxQBiO14522
PaxDbiO14522
PeptideAtlasiO14522
PRIDEiO14522
ProteomicsDBi48065
48066 [O14522-1]

PTM databases

DEPODiO14522
iPTMnetiO14522
PhosphoSitePlusiO14522

Expressioni

Tissue specificityi

Expressed in colon, lung, heart and testis, as well as in fetal and adult brain. Not detected in muscle and peripheral blood leukocytes.1 Publication

Gene expression databases

BgeeiENSG00000196090
ExpressionAtlasiO14522 baseline and differential
GenevisibleiO14522 HS

Organism-specific databases

HPAiCAB069423
HPA017336

Interactioni

Binary interactionsi

Show more details

GO - Molecular functioni

  • alpha-catenin binding Source: UniProtKB
  • beta-catenin binding Source: UniProtKB
  • cadherin binding Source: UniProtKB
  • delta-catenin binding Source: UniProtKB
  • gamma-catenin binding Source: UniProtKB
View the complete GO annotation on QuickGO ...

Protein-protein interaction databases

BioGridi116296, 7 interactors
DIPiDIP-33967N
IntActiO14522, 14 interactors
MINTiO14522
STRINGi9606.ENSP00000362283

Structurei

Secondary structure

11441
Legend: HelixTurnBeta strandPDB Structure known for this area
Show more details
Feature keyPosition(s)DescriptionActionsGraphical viewLength
Helixi871 – 873Combined sources3
Helixi874 – 882Combined sources9
Helixi889 – 895Combined sources7
Turni905 – 908Combined sources4
Helixi910 – 915Combined sources6
Helixi925 – 927Combined sources3
Helixi938 – 941Combined sources4
Beta strandi944 – 948Combined sources5
Beta strandi951 – 953Combined sources3
Beta strandi957 – 960Combined sources4
Turni965 – 967Combined sources3
Helixi968 – 978Combined sources11
Beta strandi982 – 985Combined sources4
Beta strandi989 – 991Combined sources3
Beta strandi1003 – 1009Combined sources7
Beta strandi1011 – 1020Combined sources10
Beta strandi1022 – 1033Combined sources12
Beta strandi1040 – 1047Combined sources8
Helixi1060 – 1072Combined sources13
Beta strandi1080 – 1083Combined sources4
Beta strandi1085 – 1088Combined sources4
Helixi1089 – 1107Combined sources19
Beta strandi1108 – 1110Combined sources3
Helixi1112 – 1122Combined sources11
Helixi1130 – 1145Combined sources16

3D structure databases

ProteinModelPortaliO14522
SMRiO14522
ModBaseiSearch...
MobiDBiSearch...

Miscellaneous databases

EvolutionaryTraceiO14522

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini30 – 191MAMPROSITE-ProRule annotationAdd BLAST162
Domaini193 – 284Ig-like C2-typeAdd BLAST92
Domaini291 – 384Fibronectin type-III 1PROSITE-ProRule annotationAdd BLAST94
Domaini389 – 483Fibronectin type-III 2PROSITE-ProRule annotationAdd BLAST95
Domaini484 – 590Fibronectin type-III 3PROSITE-ProRule annotationAdd BLAST107
Domaini591 – 726Fibronectin type-III 4PROSITE-ProRule annotationAdd BLAST136
Domaini889 – 1143Tyrosine-protein phosphatase 1PROSITE-ProRule annotationAdd BLAST255
Domaini1175 – 1437Tyrosine-protein phosphatase 2PROSITE-ProRule annotationAdd BLAST263

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Regioni1084 – 1090Substrate bindingBy similarity7

Sequence similaritiesi

Belongs to the protein-tyrosine phosphatase family. Receptor class 2B subfamily.Curated

Keywords - Domaini

Immunoglobulin domain, Repeat, Signal, Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiKOG4228 Eukaryota
COG5599 LUCA
GeneTreeiENSGT00760000118900
HOVERGENiHBG062785
InParanoidiO14522
KOiK13297
OMAiQYEAEEV
OrthoDBiEOG091G00CK
PhylomeDBiO14522
TreeFamiTF312900

Family and domain databases

CDDicd00063 FN3, 3 hits
cd06263 MAM, 1 hit
Gene3Di2.60.40.10, 4 hits
3.90.190.10, 2 hits
InterProiView protein in InterPro
IPR013320 ConA-like_dom_sf
IPR003961 FN3_dom
IPR036116 FN3_sf
IPR007110 Ig-like_dom
IPR036179 Ig-like_dom_sf
IPR013783 Ig-like_fold
IPR000998 MAM_dom
IPR029021 Prot-tyrosine_phosphatase-like
IPR000242 PTPase_domain
IPR016130 Tyr_Pase_AS
IPR003595 Tyr_Pase_cat
IPR000387 TYR_PHOSPHATASE_dom
PfamiView protein in Pfam
PF00041 fn3, 2 hits
PF00629 MAM, 1 hit
PF00102 Y_phosphatase, 2 hits
PRINTSiPR00020 MAMDOMAIN
PR00700 PRTYPHPHTASE
SMARTiView protein in SMART
SM00060 FN3, 3 hits
SM00137 MAM, 1 hit
SM00194 PTPc, 2 hits
SM00404 PTPc_motif, 2 hits
SUPFAMiSSF48726 SSF48726, 1 hit
SSF49265 SSF49265, 2 hits
SSF49899 SSF49899, 1 hit
SSF52799 SSF52799, 2 hits
PROSITEiView protein in PROSITE
PS50853 FN3, 3 hits
PS50835 IG_LIKE, 1 hit
PS00740 MAM_1, 1 hit
PS50060 MAM_2, 1 hit
PS00383 TYR_PHOSPHATASE_1, 2 hits
PS50056 TYR_PHOSPHATASE_2, 2 hits
PS50055 TYR_PHOSPHATASE_PTP, 2 hits

Sequences (2)i

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

This entry describes 2 isoformsi produced by alternative splicing. AlignAdd to basket

Isoform 3 (identifier: O14522-3) [UniParc]FASTAAdd to basket

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide

        10         20         30         40         50
MASLAALALS LLLRLQLPPL PGARAQSAAG GCSFDEHYSN CGYSVALGTN 
        60         70         80         90        100
GFTWEQINTW EKPMLDQAVP TGSFMMVNSS GRASGQKAHL LLPTLKENDT 
       110        120        130        140        150
HCIDFHYYFS SRDRSSPGAL NVYVKVNGGP QGNPVWNVSG VVTEGWVKAE 
       160        170        180        190        200
LAISTFWPHF YQVIFESVSL KGHPGYIAVD EVRVLAHPCR KAPHFLRLQN 
       210        220        230        240        250
VEVNVGQNAT FQCIAGGKWS QHDKLWLQQW NGRDTALMVT RVVNHRRFSA 
       260        270        280        290        300
TVSVADTAQR SVSKYRCVIR SDGGSGVSNY AELIVKEPPT PIAPPELLAV 
       310        320        330        340        350
GATYLWIKPN ANSIIGDGPI ILKEVEYRTT TGTWAETHIV DSPNYKLWHL 
       360        370        380        390        400
DPDVEYEIRV LLTRPGEGGT GPPGPPLTTR TKCADPVHGP QNVEIVDIRA 
       410        420        430        440        450
RQLTLQWEPF GYAVTRCHSY NLTVQYQYVF NQQQYEAEEV IQTSSHYTLR 
       460        470        480        490        500
GLRPFMTIRL RLLLSNPEGR MESEELVVQT EEDVPGAVPL ESIQGGPFEE 
       510        520        530        540        550
KIYIQWKPPN ETNGVITLYE INYKAVGSLD PSADLSSQRG KVFKLRNETH 
       560        570        580        590        600
HLFVGLYPGT TYSFTIKAST AKGFGPPVTT RIATKISAPS MPEYDTDTPL 
       610        620        630        640        650
NETDTTITVM LKPAQSRGAP VSVYQLVVKE ERLQKSRRAA DIIECFSVPV 
       660        670        680        690        700
SYRNASSLDS LHYFAAELKP ANLPVTQPFT VGDNKTYNGY WNPPLSPLKS 
       710        720        730        740        750
YSIYFQALSK ANGETKINCV RLATKGASTQ NSNTVEPEKQ VDNTVKMAGV 
       760        770        780        790        800
IAGLLMFIII LLGVMLTIKR RRNAYSYSYY LKLAKKQKET QSGAQREMGP 
       810        820        830        840        850
VASADKPTTK LSASRNDEGF SSSSQDVNGF TDGSRGELSQ PTLTIQTHPY 
       860        870        880        890        900
RTCDPVEMSY PRDQFQPAIR VADLLQHITQ MKRGQGYGFK EEYEALPEGQ 
       910        920        930        940        950
TASWDTAKED ENRNKNRYGN IISYDHSRVR LLVLDGDPHS DYINANYIDG 
       960        970        980        990       1000
YHRPRHYIAT QGPMQETVKD FWRMIWQENS ASIVMVTNLV EVGRVKCVRY 
      1010       1020       1030       1040       1050
WPDDTEVYGD IKVTLIETEP LAEYVIRTFT VQKKGYHEIR ELRLFHFTSW 
      1060       1070       1080       1090       1100
PDHGVPCYAT GLLGFVRQVK FLNPPEAGPI VVHCSAGAGR TGCFIAIDTM 
      1110       1120       1130       1140       1150
LDMAENEGVV DIFNCVRELR AQRVNLVQTE EQYVFVHDAI LEACLCGNTA 
      1160       1170       1180       1190       1200
IPVCEFRSLY YNISRLDPQT NSSQIKDEFQ TLNIVTPRVR PEDCSIGLLP 
      1210       1220       1230       1240       1250
RNHDKNRSMD VLPLDRCLPF LISVDGESSN YINAALMDSH KQPAAFVVTQ 
      1260       1270       1280       1290       1300
HPLPNTVADF WRLVFDYNCS SVVMLNEMDT AQFCMQYWPE KTSGCYGPIQ 
      1310       1320       1330       1340       1350
VEFVSADIDE DIIHRIFRIC NMARPQDGYR IVQHLQYIGW PAYRDTPPSK 
      1360       1370       1380       1390       1400
RSLLKVVRRL EKWQEQYDGR EGRTVVHCLN GGGRSGTFCA ICSVCEMIQQ 
      1410       1420       1430       1440 
QNIIDVFHIV KTLRNNKSNM VETLEQYKFV YEVALEYLSS F
Length:1,441
Mass (Da):162,134
Last modified:January 11, 2011 - v6
Checksum:iBE60F3DB2CE13539
GO
Isoform 1 (identifier: O14522-1) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     725-725: K → KAPMGSAQVTPGTPLCLLTT
     781-781: L → LSQR

Show »
Length:1,463
Mass (Da):164,346
Checksum:i531E33DF9040F4B5
GO

Sequence cautioni

The sequence BAA22952 differs from that shown. Reason: Erroneous initiation. Translation N-terminally shortened.Curated
The sequence CAH72555 differs from that shown. Reason: Erroneous gene model prediction.Curated
The sequence CAI19251 differs from that shown. Reason: Erroneous gene model prediction.Curated
The sequence CAI19867 differs from that shown. Reason: Erroneous gene model prediction.Curated
The sequence CAI19879 differs from that shown. Reason: Erroneous gene model prediction.Curated
The sequence CAI19983 differs from that shown. Reason: Erroneous gene model prediction.Curated
The sequence CAI20439 differs from that shown. Reason: Erroneous gene model prediction.Curated
The sequence CAI22491 differs from that shown. Reason: Erroneous gene model prediction.Curated
The sequence CAI22911 differs from that shown. Reason: Erroneous gene model prediction.Curated
The sequence CAI23312 differs from that shown. Reason: Erroneous gene model prediction.Curated

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Sequence conflicti60W → T in AAD09421 (PubMed:9602027).Curated1
Sequence conflicti375P → A in AAD09421 (PubMed:9602027).Curated1
Sequence conflicti867P → L in AAD09421 (PubMed:9602027).Curated1

Natural variant

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Natural variantiVAR_02879529A → P3 PublicationsCorresponds to variant dbSNP:rs2867655Ensembl.1
Natural variantiVAR_02074674F → S in a colorectal cancer. 1 Publication1
Natural variantiVAR_02879676M → V. Corresponds to variant dbSNP:rs17811401Ensembl.1
Natural variantiVAR_020747209A → T in some colorectal cancers. 1 Publication1
Natural variantiVAR_020748218K → T in a gastric cancer. 1 Publication1
Natural variantiVAR_020749248F → S in a colorectal cancer. 1 Publication1
Natural variantiVAR_020750280Y → H in a colorectal cancer. 1 Publication1
Natural variantiVAR_020751395I → V in a colorectal cancer. 1 Publication1
Natural variantiVAR_020752412Y → F in a colorectal cancer. 1 Publication1
Natural variantiVAR_020753453R → C in a gastric cancer. 1 Publication1
Natural variantiVAR_020754510N → K in a colorectal cancer. 1 PublicationCorresponds to variant dbSNP:rs749647294Ensembl.1
Natural variantiVAR_020755605T → M in a colorectal cancer. 1 Publication1
Natural variantiVAR_020756648V → G in a colorectal cancer. 1 Publication1
Natural variantiVAR_020757707A → T in a colorectal cancer. 1 Publication1
Natural variantiVAR_020758707A → V in a colorectal cancer. 1 Publication1
Natural variantiVAR_020759708L → P in a colorectal cancer. 1 Publication1
Natural variantiVAR_020760771R → I in a lung cancer. 1 Publication1
Natural variantiVAR_020761905D → G in a colorectal cancer. 1 Publication1
Natural variantiVAR_020762965Q → K in a colorectal cancer; reduced phosphatase activity. 1 Publication1
Natural variantiVAR_0207631096A → P in a colorectal cancer. 1 Publication1
Natural variantiVAR_0207641106N → I in a colorectal cancer; reduced phosphatase activity. 1 Publication1
Natural variantiVAR_0207651190R → W in a colorectal cancer; reduced phosphatase activity. 1 PublicationCorresponds to variant dbSNP:rs370873414Ensembl.1
Natural variantiVAR_0541441213P → L in an acute myeloid leukemia sample; somatic mutation. 1 Publication1
Natural variantiVAR_0207661237M → L in a colorectal cancer. 1 Publication1
Natural variantiVAR_0207671247V → M in a colorectal cancer. 1 PublicationCorresponds to variant dbSNP:rs761148007Ensembl.1
Natural variantiVAR_0207681324R → L in a lung cancer; reduced phosphatase activity. 1 Publication1
Natural variantiVAR_0207691329Y → F in a colorectal cancer. 1 Publication1
Natural variantiVAR_0207701346T → M Found in a patient with severe intellectual disability, behavioral problems, microcephaly, congenital cardiac defect and herniation of the abdominal diaphragm; also observed in some colorectal cancers; reduced phosphatase activity; unknown pathological significance. 2 PublicationsCorresponds to variant dbSNP:rs199947379Ensembl.1

Alternative sequence

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Alternative sequenceiVSP_040385725K → KAPMGSAQVTPGTPLCLLTT in isoform 1. 1 Publication1
Alternative sequenceiVSP_040386781L → LSQR in isoform 1. 1 Publication1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF043644 mRNA Translation: AAD09421.2
AB006621 mRNA Translation: BAA22952.2 Different initiation.
AL021395
, AL022239, AL024473, AL031656, AL035459, AL049812, AL121763, AL136461, Z93942 Genomic DNA Translation: CAI19981.1
AL021395
, AL022239, AL024473, AL031656, AL035459, AL049812, AL121763, AL136461, Z93942 Genomic DNA Translation: CAI19983.1 Sequence problems.
AL022239
, AL021395, AL024473, AL031656, AL035459, AL049812, AL121763, AL136461, Z93942 Genomic DNA Translation: CAI20437.1
AL022239
, AL021395, AL024473, AL031656, AL035459, AL049812, AL121763, AL136461, Z93942 Genomic DNA Translation: CAI20439.1 Sequence problems.
AL024473
, AL021395, AL022239, AL031656, AL035459, AL049812, AL121763, AL136461, Z93942 Genomic DNA Translation: CAI22489.1
AL024473
, AL021395, AL022239, AL031656, AL035459, AL049812, AL121763, AL136461, Z93942 Genomic DNA Translation: CAI22491.1 Sequence problems.
AL031656
, AL021395, AL022239, AL024473, AL035459, AL049812, AL121763, AL136461, Z93942 Genomic DNA Translation: CAI19877.1
AL031656
, AL021395, AL022239, AL024473, AL035459, AL049812, AL121763, AL136461, Z93942 Genomic DNA Translation: CAI19879.1 Sequence problems.
AL035459
, AL021395, AL022239, AL024473, AL031656, AL049812, AL121763, AL136461, Z93942 Genomic DNA Translation: CAI22909.1
AL035459
, AL021395, AL022239, AL024473, AL031656, AL049812, AL121763, AL136461, Z93942 Genomic DNA Translation: CAI22911.1 Sequence problems.
AL049812
, AL021395, AL022239, AL024473, AL031656, AL035459, AL121763, AL136461, Z93942 Genomic DNA Translation: CAI19251.1 Sequence problems.
AL049812
, AL022239, AL031656, AL021395, AL024473, AL035459, AL121763, AL136461, Z93942 Genomic DNA Translation: CAI19253.1
AL121763
, AL021395, AL022239, AL024473, AL031656, AL035459, AL049812, AL136461, Z93942 Genomic DNA Translation: CAI23310.1
AL121763
, AL021395, AL022239, AL024473, AL031656, AL035459, AL049812, AL136461, Z93942 Genomic DNA Translation: CAI23312.1 Sequence problems.
AL136461
, AL021395, AL022239, AL024473, AL031656, AL035459, AL049812, AL121763, Z93942 Genomic DNA Translation: CAH72553.1
AL136461
, AL021395, AL022239, AL024473, AL031656, AL035459, AL049812, AL121763, Z93942 Genomic DNA Translation: CAH72555.1 Sequence problems.
Z93942
, AL021395, AL022239, AL024473, AL031656, AL035459, AL049812, AL121763, AL136461 Genomic DNA Translation: CAI19865.1
Z93942
, AL021395, AL022239, AL024473, AL031656, AL035459, AL049812, AL121763, AL136461 Genomic DNA Translation: CAI19867.1 Sequence problems.
AL031676 Genomic DNA No translation available.
AL035666 Genomic DNA No translation available.
AL109826 Genomic DNA No translation available.
AL117374 Genomic DNA No translation available.
AL359695 Genomic DNA No translation available.
BC153300 mRNA Translation: AAI53301.1
CCDSiCCDS42874.1 [O14522-3]
RefSeqiNP_008981.4, NM_007050.5 [O14522-3]
NP_573400.3, NM_133170.3
UniGeneiHs.526879

Genome annotation databases

EnsembliENST00000373187; ENSP00000362283; ENSG00000196090 [O14522-3]
ENST00000373193; ENSP00000362289; ENSG00000196090 [O14522-1]
GeneIDi11122
KEGGihsa:11122
UCSCiuc002xkg.4 human [O14522-3]

Keywords - Coding sequence diversityi

Alternative splicing, Polymorphism

Similar proteinsi

Entry informationi

Entry nameiPTPRT_HUMAN
AccessioniPrimary (citable) accession number: O14522
Secondary accession number(s): A8E4R6
, O43655, O75664, Q5W0X9, Q5W0Y1, Q9BR24, Q9BR28, Q9H0Y8, Q9NTL1, Q9NU72, Q9UBD2, Q9UJL7
Entry historyiIntegrated into UniProtKB/Swiss-Prot: July 19, 2003
Last sequence update: January 11, 2011
Last modified: July 18, 2018
This is version 166 of the entry and version 6 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

3D-structure, Complete proteome, Reference proteome

Documents

  1. Human chromosome 20
    Human chromosome 20: entries, gene names and cross-references to MIM
  2. Human entries with polymorphisms or disease mutations
    List of human entries with polymorphisms or disease mutations
  3. Human polymorphisms and disease mutations
    Index of human polymorphisms and disease mutations
  4. MIM cross-references
    Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
  5. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  6. SIMILARITY comments
    Index of protein domains and families

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