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1 to 18 of 18  Show
  1. 1
    "A novel ligand for an SH3 domain of the adaptor protein Nck bears an SH2 domain and nuclear signaling motifs."
    Matuoka K., Miki H., Takahashi K., Takenawa T.
    Biochem. Biophys. Res. Commun. 239:488-492(1997) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 2), TISSUE SPECIFICITY, INTERACTION WITH NCK1; GRB2 AND PLCG1.
    Category: Expression, Interaction, Sequences.
    Tissue: Brain.
    Source: UniProtKB/Swiss-Prot (reviewed).

    This publication is cited by 2 other entries.

  2. 2
    Category: Sequences.
    Source: UniProtKB/Swiss-Prot (reviewed).

    This publication is cited by 4676 other entries.

  3. 3
    "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
    The MGC Project Team
    Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 147-581.
    Category: Sequences.
    Source: UniProtKB/Swiss-Prot (reviewed).

    This publication is cited by 50446 other entries.

  4. 4
    "Expression of SOCS genes in normal and leukemic human leukocytes stimulated by prolactin, growth hormone and cytokines."
    Dogusan Z., Hooghe-Peters E.L., Berus D., Velkeniers B., Hooghe R.
    J. Neuroimmunol. 109:34-39(2000) [PubMed] [Europe PMC] [Abstract]
    Cited for: INDUCTION.
    Category: Expression.
    Source: UniProtKB/Swiss-Prot (reviewed).
  5. 5
    "The suppressor of cytokine signaling (SOCS)-7 interacts with the actin cytoskeleton through vinexin."
    Martens N., Wery M., Wang P., Braet F., Gertler A., Hooghe R., Vandenhaute J., Hooghe-Peters E.L.
    Exp. Cell Res. 298:239-248(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: INTERACTION WITH SORBS3, SUBCELLULAR LOCATION.
    Category: Subcellular Location, Interaction.
    Source: UniProtKB/Swiss-Prot (reviewed).

    This publication is cited by 3 other entries.

  6. 6
    "Suppressor of cytokine signaling 7 inhibits prolactin, growth hormone, and leptin signaling by interacting with STAT5 or STAT3 and attenuating their nuclear translocation."
    Martens N., Uzan G., Wery M., Hooghe R., Hooghe-Peters E.L., Gertler A.
    J. Biol. Chem. 280:13817-13823(2005) [PubMed] [Europe PMC] [Abstract]
    Cited for: FUNCTION, INTERACTION WITH STAT3 AND STAT5.
    Category: Function, Interaction.
    Source: UniProtKB/Swiss-Prot (reviewed).

    This publication is cited by 3 and mapped to 15 other entries.

  7. 7
    "Deletion of SOCS7 leads to enhanced insulin action and enlarged islets of Langerhans."
    Banks A.S., Li J., McKeag L., Hribal M.L., Kashiwada M., Accili D., Rothman P.B.
    J. Clin. Invest. 115:2462-2471(2005) [PubMed] [Europe PMC] [Abstract]
    Cited for: FUNCTION, INTERACTION WITH INSR AND IRS1, MUTAGENESIS OF 425-ARG--SER-427.
    Category: Function, Pathology & Biotech, Interaction.
    Source: UniProtKB/Swiss-Prot (reviewed).

    This publication is cited by 3 and mapped to 10 other entries.

  8. 8
    "Septins regulate actin organization and cell-cycle arrest through nuclear accumulation of NCK mediated by SOCS7."
    Kremer B.E., Adang L.A., Macara I.G.
    Cell 130:837-850(2007) [PubMed] [Europe PMC] [Abstract]
    Cited for: INTERACTION WITH SEPT6, SUBCELLULAR LOCATION.
    Category: Subcellular Location, Interaction.
    Source: UniProtKB/Swiss-Prot (reviewed).

    This publication is cited by 4 and mapped to 31 other entries.

  9. 9
    "Hepatitis C virus core protein genotype 3a increases SOCS-7 expression through PPAR-{gamma} in Huh-7 cells."
    Pazienza V., Vinciguerra M., Andriulli A., Mangia A.
    J. Gen. Virol. 91:1678-1686(2010) [PubMed] [Europe PMC] [Abstract]
    Category: Function.
    Annotation: findings show that PPAR-gamma is involved in the regulation of SOCS-7 expression by hepatitis C virus core protein genotype 3a.
    Source: GeneRIF:30837.

    This publication is mapped to 13 other entries.

  10. 10
    "Higher expression levels of SOCS 1,3,4,7 are associated with earlier tumour stage and better clinical outcome in human breast cancer."
    Sasi W., Jiang W.G., Sharma A., Mokbel K.
    BMC Cancer 10:178-178(2010) [PubMed] [Europe PMC] [Abstract]
    Category: Expression.
    Annotation: Higher mRNA expression levels of SOCS1 3 4 and 7 are significantly associated with earlier tumour stage and better clinical outcome in human breast cancer.
    Source: GeneRIF:30837.

    This publication is mapped to 5 other entries.

  11. 11
    "Abi1/Hssh3bp1 pY213 links Abl kinase signaling to p85 regulatory subunit of PI-3 kinase in regulation of macropinocytosis in LNCaP cells."
    Dubielecka P.M., Machida K., Xiong X., Hossain S., Ogiue-Ikeda M., Carrera A.C., Mayer B.J., Kotula L.
    FEBS Lett. 584:3279-3286(2010) [PubMed] [Europe PMC] [Abstract]
    Category: Interaction.
    Source: IntAct:O14512.

    This publication is mapped to 75 other entries.

  12. 12
    "LNCaP prostate cancer cells with autocrine interleukin-6 expression are resistant to IL-6-induced neuroendocrine differentiation due to increased expression of suppressors of cytokine signaling."
    Ge D., Gao A.C., Zhang Q., Liu S., Xue Y., You Z.
    Prostate 72:1306-1316(2012) [PubMed] [Europe PMC] [Abstract]
    Category: Function.
    Annotation: LNCaP-S17 cells are resistant to exogenous IL-6-induced neuroendocrine differentiation due to increased levels of CIS/SOCS7 that block activation of JAK2-STAT3 pathways.
    Source: GeneRIF:30837.

    This publication is mapped to 2 other entries.

  13. 13
    "Common variants in SOCS7 gene predict obesity, disturbances in lipid metabolism and insulin resistance."
    Tellechea M.L., Steinhardt A.P., Rodriguez G., Taverna M.J., Poskus E., Frechtel G.
    Nutr Metab Cardiovasc Dis 23:424-431(2013) [PubMed] [Europe PMC] [Abstract]
    Category: Pathology & Biotech, Sequences.
    Annotation: The present report describes for the first time associations between common variants in SOCS7 gene and obesity central obesity insulin resistance and disorders of lipid metabolism in nondiabetic men from Argentina.
    Source: GeneRIF:30837.
  14. 14
    "socs7, a target gene of microRNA-145, regulates interferon-beta induction through STAT3 nuclear translocation in bladder cancer cells."
    Noguchi S., Yamada N., Kumazaki M., Yasui Y., Iwasaki J., Naito S., Akao Y.
    Cell Death Dis 4:e482-e482(2013) [PubMed] [Europe PMC] [Abstract]
    Category: Function.
    Annotation: SOCS7 functioned as an oncogene the finding that revealed a novel mechanism of carcinogenesis in bladder cancer cells.
    Source: GeneRIF:30837.
  15. 15
    Category: Pathology & Biotech, Sequences.
    Annotation: genetic variants in the SOCS7 gene do not impact variation in glucose homeostasis traits and only minimally impact risk of T2DM in the Old Order Amish.
    Source: GeneRIF:30837.
  16. 16
    "Observations on the effects of Suppressor of Cytokine Signaling 7 (SOCS7) knockdown in breast cancer cells: their in vitro response to Insulin Like Growth Factor I (IGF-I)."
    Sasi W., Ye L., Jiang W.G., Mokbel K., Sharma A.
    Clin Transl Oncol 16:476-487(2014) [PubMed] [Europe PMC] [Abstract]
    Category: Function.
    Annotation: Insulin Like Growth Factor I treatment and SOCS7 loss have synergistically resulted in increased growth and migration of MCF7 and in increased migration of MDA-MB-231 cells.
    Source: GeneRIF:30837.
  17. 17
    "In vitro and in vivo effects of suppressor of cytokine signalling 7 knockdown in breast cancer: the influence on cellular response to hepatocyte growth factor."
    Sasi W., Ye L., Jiang W.G., Sharma A.K., Mokbel K.
    Biomed Res Int 2014:648040-648040(2014) [PubMed] [Europe PMC] [Abstract]
    Category: Function.
    Annotation: This SOCS7 knockdown-attributed effect could be due to a precise anti-PLCg-1 role.
    Source: GeneRIF:30837.

    This publication is mapped to 10 other entries.

  18. 18
    "Expression of suppressor of cytokine signaling genes in human elderly and Alzheimer's disease brains and human microglia."
    Walker D.G., Whetzel A.M., Lue L.F.
    Neuroscience 302:121-137(2015) [PubMed] [Europe PMC] [Abstract]
    Category: Expression, Sequences.
    Annotation: This study showed that increased protein levels of SOCS-4 and SOCS-7 in Alzheimer's disease brains.
    Source: GeneRIF:30837.

    This publication is mapped to 12 other entries.

1 to 18 of 18  Show
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