UniProtKB - O14091 (SUT1_SCHPO)
Protein
General alpha-glucoside permease
Gene
sut1
Organism
Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Status
Functioni
Responsible for the transport of maltose and sucrose into the cell, with the concomitant uptake of protons (symport system).1 Publication
GO - Molecular functioni
- maltose:proton symporter activity Source: PomBase
- sucrose:proton symporter activity Source: PomBase
GO - Biological processi
- fructose transmembrane transport Source: GOC
- maltose import across plasma membrane Source: PomBase
- mannitol transport Source: GOC
- raffinose transport Source: GOC
- sucrose import across plasma membrane Source: PomBase
Keywordsi
Biological process | Sugar transport, Symport, Transport |
Enzyme and pathway databases
Reactomei | R-SPO-189200, Cellular hexose transport |
Protein family/group databases
TCDBi | 2.A.2.6.1, the glycoside-pentoside-hexuronide (gph):cation symporter family |
Names & Taxonomyi
Protein namesi | Recommended name: General alpha-glucoside permease |
Gene namesi | Name:sut1 ORF Names:SPAC2F3.08 |
Organismi | Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) |
Taxonomic identifieri | 284812 [NCBI] |
Taxonomic lineagei | Eukaryota › Fungi › Dikarya › Ascomycota › Taphrinomycotina › Schizosaccharomycetes › Schizosaccharomycetales › Schizosaccharomycetaceae › Schizosaccharomyces › |
Proteomesi |
|
Organism-specific databases
PomBasei | SPAC2F3.08, sut1 |
VEuPathDBi | FungiDB:SPAC2F3.08 |
Subcellular locationi
Other locations
- Membrane Curated; Multi-pass membrane protein Curated
Golgi apparatus
- Golgi apparatus Source: PomBase
Plasma Membrane
- integral component of plasma membrane Source: PomBase
Vacuole
- fungal-type vacuole membrane Source: PomBase
Other locations
- membrane Source: GO_Central
Topology
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Topological domaini | 1 – 33 | CytoplasmicSequence analysisAdd BLAST | 33 | |
Transmembranei | 34 – 54 | HelicalSequence analysisAdd BLAST | 21 | |
Topological domaini | 55 – 72 | ExtracellularSequence analysisAdd BLAST | 18 | |
Transmembranei | 73 – 93 | HelicalSequence analysisAdd BLAST | 21 | |
Topological domaini | 94 – 111 | CytoplasmicSequence analysisAdd BLAST | 18 | |
Transmembranei | 112 – 132 | HelicalSequence analysisAdd BLAST | 21 | |
Topological domaini | 133 – 140 | ExtracellularSequence analysis | 8 | |
Transmembranei | 141 – 161 | HelicalSequence analysisAdd BLAST | 21 | |
Topological domaini | 162 – 186 | CytoplasmicSequence analysisAdd BLAST | 25 | |
Transmembranei | 187 – 207 | HelicalSequence analysisAdd BLAST | 21 | |
Topological domaini | 208 – 216 | ExtracellularSequence analysis | 9 | |
Transmembranei | 217 – 237 | HelicalSequence analysisAdd BLAST | 21 | |
Topological domaini | 238 – 280 | CytoplasmicSequence analysisAdd BLAST | 43 | |
Transmembranei | 281 – 301 | HelicalSequence analysisAdd BLAST | 21 | |
Topological domaini | 302 – 322 | ExtracellularSequence analysisAdd BLAST | 21 | |
Transmembranei | 323 – 343 | HelicalSequence analysisAdd BLAST | 21 | |
Topological domaini | 344 – 424 | CytoplasmicSequence analysisAdd BLAST | 81 | |
Transmembranei | 425 – 445 | HelicalSequence analysisAdd BLAST | 21 | |
Topological domaini | 446 – 452 | ExtracellularSequence analysis | 7 | |
Transmembranei | 453 – 473 | HelicalSequence analysisAdd BLAST | 21 | |
Topological domaini | 474 – 494 | CytoplasmicSequence analysisAdd BLAST | 21 | |
Transmembranei | 495 – 515 | HelicalSequence analysisAdd BLAST | 21 | |
Topological domaini | 516 – 521 | ExtracellularSequence analysis | 6 | |
Transmembranei | 522 – 542 | HelicalSequence analysisAdd BLAST | 21 | |
Topological domaini | 543 – 553 | CytoplasmicSequence analysisAdd BLAST | 11 |
Keywords - Cellular componenti
MembranePTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
ChainiPRO_0000122532 | 1 – 553 | General alpha-glucoside permeaseAdd BLAST | 553 |
Proteomic databases
MaxQBi | O14091 |
PaxDbi | O14091 |
PRIDEi | O14091 |
PTM databases
iPTMneti | O14091 |
Interactioni
Protein-protein interaction databases
BioGRIDi | 278450, 15 interactors |
STRINGi | 4896.SPAC2F3.08.1 |
Family & Domainsi
Sequence similaritiesi
Belongs to the glycoside-pentoside-hexuronide (GPH) cation symporter transporter (TC 2.A.2.4) family. [View classification]Curated
Keywords - Domaini
Transmembrane, Transmembrane helixPhylogenomic databases
eggNOGi | KOG0637, Eukaryota |
HOGENOMi | CLU_018303_1_1_1 |
InParanoidi | O14091 |
OMAi | QFKVLCA |
PhylomeDBi | O14091 |
Family and domain databases
InterProi | View protein in InterPro IPR036259, MFS_trans_sf |
SUPFAMi | SSF103473, SSF103473, 1 hit |
i Sequence
Sequence statusi: Complete.
O14091-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MSVDENQLEN GQLLSSENEA SSPFKESIPS RSSLYLIALT VSLLGVQLTW
60 70 80 90 100
SVELGYGTPY LFSLGLRKEW TSIIWIAGPL TGILIQPIAG ILSDRVNSRI
110 120 130 140 150
GRRRPFMLCA SLLGTFSLFL MGWAPDICLF IFSNEVLMKR VTIVLATISI
160 170 180 190 200
YLLDVAVNVV MASTRSLIVD SVRSDQQHEA NSWAGRMIGV GNVLGYLLGY
210 220 230 240 250
LPLYRIFSFL NFTQLQVFCV LASISLVLTV TITTIFVSER RFPPVEHEKS
260 270 280 290 300
VAGEIFEFFT TMRQSITALP FTLKRICFVQ FFAYFGWFPF LFYITTYVGI
310 320 330 340 350
LYLRHAPKGH EEDWDMATRQ GSFALLLFAI ISLAANTALP LLLEDTEDDE
360 370 380 390 400
EDESSDASNN EYNIQERNDL GNIRTGTNTP RLGNLSETTS FRSENEPSRR
410 420 430 440 450
RLLPSSRSIM TTISSKVQIK GLTLPILWLS SHVLFGVCML STIFLQTSWQ
460 470 480 490 500
AQAMVAICGL SWACTLWIPY SLFSSEIGKL GLRESSGKMI GVHNVFISAP
510 520 530 540 550
QVLSTIIATI VFIQSEGSHR DIADNSIAWV LRIGGISAFL AAYQCRHLLP
INF
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | CU329670 Genomic DNA Translation: CAB16264.1 AB027797 Genomic DNA Translation: BAA87101.1 |
PIRi | T38541 |
RefSeqi | NP_594387.1, NM_001019808.2 |
Genome annotation databases
EnsemblFungii | SPAC2F3.08.1; SPAC2F3.08.1:pep; SPAC2F3.08 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | CU329670 Genomic DNA Translation: CAB16264.1 AB027797 Genomic DNA Translation: BAA87101.1 |
PIRi | T38541 |
RefSeqi | NP_594387.1, NM_001019808.2 |
3D structure databases
ModBasei | Search... |
SWISS-MODEL-Workspacei | Submit a new modelling project... |
Protein-protein interaction databases
BioGRIDi | 278450, 15 interactors |
STRINGi | 4896.SPAC2F3.08.1 |
Protein family/group databases
TCDBi | 2.A.2.6.1, the glycoside-pentoside-hexuronide (gph):cation symporter family |
PTM databases
iPTMneti | O14091 |
Proteomic databases
MaxQBi | O14091 |
PaxDbi | O14091 |
PRIDEi | O14091 |
Genome annotation databases
EnsemblFungii | SPAC2F3.08.1; SPAC2F3.08.1:pep; SPAC2F3.08 |
Organism-specific databases
PomBasei | SPAC2F3.08, sut1 |
VEuPathDBi | FungiDB:SPAC2F3.08 |
Phylogenomic databases
eggNOGi | KOG0637, Eukaryota |
HOGENOMi | CLU_018303_1_1_1 |
InParanoidi | O14091 |
OMAi | QFKVLCA |
PhylomeDBi | O14091 |
Enzyme and pathway databases
Reactomei | R-SPO-189200, Cellular hexose transport |
Miscellaneous databases
PROi | PR:O14091 |
Family and domain databases
InterProi | View protein in InterPro IPR036259, MFS_trans_sf |
SUPFAMi | SSF103473, SSF103473, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | SUT1_SCHPO | |
Accessioni | O14091Primary (citable) accession number: O14091 Secondary accession number(s): Q9UU60 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | December 6, 2002 |
Last sequence update: | January 1, 1998 | |
Last modified: | February 10, 2021 | |
This is version 125 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Fungal Protein Annotation Program |
Miscellaneousi
Keywords - Technical termi
Reference proteomeDocuments
- SIMILARITY comments
Index of protein domains and families - Schizosaccharomyces pombe
Schizosaccharomyces pombe: entries and gene names