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Entry version 129 (29 Sep 2021)
Sequence version 1 (01 Jan 1998)
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Protein

Putative alpha,alpha-trehalose-phosphate synthase [UDP-forming] 106 kDa subunit

Gene

SPAC2E11.16c

Organism
Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Status
Reviewed-Annotation score:

Annotation score:3 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>This subsection of the <a href="http://www.uniprot.org/help/function_section">Function</a> section describes the catalytic activity of an enzyme, i.e. a chemical reaction that the enzyme catalyzes.<p><a href='/help/catalytic_activity' target='_top'>More...</a></p>Catalytic activityi

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionGlycosyltransferase, Transferase

Protein family/group databases

Carbohydrate-Active enZymes

More...
CAZyi
GT20, Glycosyltransferase Family 20

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Putative alpha,alpha-trehalose-phosphate synthase [UDP-forming] 106 kDa subunit (EC:2.4.1.15)
Alternative name(s):
Trehalose-6-phosphate synthase
UDP-glucose-glucosephosphate glucosyltransferase
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
ORF Names:SPAC2E11.16c, SPACUNK4.16c
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiSchizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri284812 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaTaphrinomycotinaSchizosaccharomycetesSchizosaccharomycetalesSchizosaccharomycetaceaeSchizosaccharomyces
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000002485 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome I

Organism-specific databases

Schizosaccharomyces pombe database

More...
PomBasei
SPACUNK4.16c

Eukaryotic Pathogen, Vector and Host Database Resources

More...
VEuPathDBi
FungiDB:SPACUNK4.16c

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00001225121 – 944Putative alpha,alpha-trehalose-phosphate synthase [UDP-forming] 106 kDa subunitAdd BLAST944

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section specifies the position and type of each modified residue excluding <a href="http://www.uniprot.org/manual/lipid">lipids</a>, <a href="http://www.uniprot.org/manual/carbohyd">glycans</a> and <a href="http://www.uniprot.org/manual/crosslnk">protein cross-links</a>.<p><a href='/help/mod_res' target='_top'>More...</a></p>Modified residuei141Phosphoserine1 Publication1
Modified residuei145Phosphoserine1 Publication1
Modified residuei149Phosphoserine1 Publication1
Modified residuei150Phosphoserine1 Publication1
Modified residuei163Phosphoserine1 Publication1
Modified residuei177Phosphoserine1 Publication1
Modified residuei189Phosphothreonine1 Publication1

Keywords - PTMi

Phosphoprotein

Proteomic databases

MaxQB - The MaxQuant DataBase

More...
MaxQBi
O14081

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
O14081

PRoteomics IDEntifications database

More...
PRIDEi
O14081

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
O14081

SwissPalm database of S-palmitoylation events

More...
SwissPalmi
O14081

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGRID)

More...
BioGRIDi
278957, 19 interactors

STRING: functional protein association networks

More...
STRINGi
4896.SPACUNK4.16c.1

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
O14081

Database of comparative protein structure models

More...
ModBasei
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni73 – 113DisorderedSequence analysisAdd BLAST41
Regioni129 – 166DisorderedSequence analysisAdd BLAST38
Regioni173 – 652GlycosyltransferaseAdd BLAST480

<p>This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

In the N-terminal section; belongs to the glycosyltransferase 20 family.Curated

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG1050, Eukaryota

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
CLU_002351_2_2_1

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
O14081

Identification of Orthologs from Complete Genome Data

More...
OMAi
KGTDAKW

Database for complete collections of gene phylogenies

More...
PhylomeDBi
O14081

Family and domain databases

Conserved Domains Database

More...
CDDi
cd03788, GT20_TPS, 1 hit

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
3.40.50.1000, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR001830, Glyco_trans_20
IPR036412, HAD-like_sf
IPR023214, HAD_sf
IPR003337, Trehalose_PPase

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF00982, Glyco_transf_20, 1 hit
PF02358, Trehalose_PPase, 1 hit

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF56784, SSF56784, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

O14081-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MGRILIAHLF LPSSVGFSFD TVPHDEVGSK FMQKEESKDW IADTPLDESA
60 70 80 90 100
IVSEEESDDD SLLSDLPEEI DSTNAQSNIA TPSPGTVAAA ISGIQPPPKT
110 120 130 140 150
PSSDSPSLEN SLSNLNDLFK SRGRHMAFSK NDGTNLSLPP SRHQSPPPSS
160 170 180 190 200
VLASQRHHRR HDSELEEFAR RASRSLSFSM NGTPQRRMTF DAEAWKNVIF
210 220 230 240 250
KIKPSSFGNA SFYNAISAAT RSKQFDDHLF VGTCGIPTDS LPDSLKERIS
260 270 280 290 300
HDYITEHSSL VVYPTDTDFV GHYNHYCKNI LWPTFHYQIP DNPKSKAYED
310 320 330 340 350
HSWANYVKVN KAFADTIVDN YEQDDMIWIN DYHLLLVPEM VRERLPRAKI
360 370 380 390 400
GFFLHIPFPS SEVFRCLATR QEILKGMLGA NILGFQIPEF AYHFLQTCSR
410 420 430 440 450
LVNIDIRKNG VVSFENRQID VIALPISIDP GFIDRCLASP PVEHWAKVLQ
460 470 480 490 500
DRFRGKHIIL SHDKLDPIRG LRSKLISFER FLQKYPEYRE NTILLQVAPE
510 520 530 540 550
SLQDSEHLPH ISDIVTRINS AYSNIASRHV PVILLRQKLG YAQFLALMMI
560 570 580 590 600
SDALIDNSLR EGISLTSHQF IYVQRKRHRP LILSEFVGSA SILNDNAIIV
610 620 630 640 650
NPWDYSKTAE AFRTALTMSE EECQKRNKAM CNLILRHDAA SWAVTFQSLI
660 670 680 690 700
KESWKEQIDM QRIPAFTAQL IKEPYQNAQK RLILLYFEGT ISTWGSQYHN
710 720 730 740 750
VMTSLQRTIN LLNMLTSDPK NTVYVFSALS CQELEQLFQR VPKLGIVAEN
760 770 780 790 800
GCFVRSPPKG DATMPVSKKE IAELWKNKVL GTDLTWMKTV SEIFEYYAER
810 820 830 840 850
TTGAYVENKD ATVILHLREA EDDEAAMWAA KECCESVNNF NVPCSATIQN
860 870 880 890 900
DMVVCRSNKV SKRLAAEDIY SANGGDYDFI FAASNDPDDD TVFSWMKNFK
910 920 930 940
QSKKEVVPFT FSVCVSEHGN STNADAESSG VFGFLQALEK VYSA
Length:944
Mass (Da):106,818
Last modified:January 1, 1998 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iD9B48874CCCB1A8A
GO

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
CU329670 Genomic DNA Translation: CAA20146.1

Protein sequence database of the Protein Information Resource

More...
PIRi
T41711

NCBI Reference Sequences

More...
RefSeqi
NP_593962.1, NM_001019389.2

Genome annotation databases

Ensembl fungal genome annotation project

More...
EnsemblFungii
SPACUNK4.16c.1; SPACUNK4.16c.1:pep; SPACUNK4.16c

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
2542498

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
spo:SPACUNK4.16c

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CU329670 Genomic DNA Translation: CAA20146.1
PIRiT41711
RefSeqiNP_593962.1, NM_001019389.2

3D structure databases

SMRiO14081
ModBaseiSearch...

Protein-protein interaction databases

BioGRIDi278957, 19 interactors
STRINGi4896.SPACUNK4.16c.1

Protein family/group databases

CAZyiGT20, Glycosyltransferase Family 20

PTM databases

iPTMnetiO14081
SwissPalmiO14081

Proteomic databases

MaxQBiO14081
PaxDbiO14081
PRIDEiO14081

Genome annotation databases

EnsemblFungiiSPACUNK4.16c.1; SPACUNK4.16c.1:pep; SPACUNK4.16c
GeneIDi2542498
KEGGispo:SPACUNK4.16c

Organism-specific databases

PomBaseiSPACUNK4.16c
VEuPathDBiFungiDB:SPACUNK4.16c

Phylogenomic databases

eggNOGiKOG1050, Eukaryota
HOGENOMiCLU_002351_2_2_1
InParanoidiO14081
OMAiKGTDAKW
PhylomeDBiO14081

Miscellaneous databases

Protein Ontology

More...
PROi
PR:O14081

Family and domain databases

CDDicd03788, GT20_TPS, 1 hit
Gene3Di3.40.50.1000, 1 hit
InterProiView protein in InterPro
IPR001830, Glyco_trans_20
IPR036412, HAD-like_sf
IPR023214, HAD_sf
IPR003337, Trehalose_PPase
PfamiView protein in Pfam
PF00982, Glyco_transf_20, 1 hit
PF02358, Trehalose_PPase, 1 hit
SUPFAMiSSF56784, SSF56784, 1 hit

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiTPSX_SCHPO
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: O14081
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: November 1, 2002
Last sequence update: January 1, 1998
Last modified: September 29, 2021
This is version 129 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteome

Documents

  1. Schizosaccharomyces pombe
    Schizosaccharomyces pombe: entries and gene names
  2. SIMILARITY comments
    Index of protein domains and families
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