Glutathione transporter 1

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functionⁱ

<p>This subsection of the 'Function' section describes biophysical and chemical properties, such as maximal absorption, kinetic parameters, pH dependence, redox potentials and temperature dependence.<p><a href='/help/biophysicochemical_properties' target='_top'>More...</a></p>Kineticsⁱ

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functionⁱ

• glutathione transmembrane transporter activity Source: PomBase <p>Inferred from Direct Assay</p> <p>Used to indicate a direct assay for the function, process or component indicated by the GO term.</p> <p>More information in the <a href="http://geneontology.org/page/guide%2Dgo%2Devidence%2Dcodes#ida">GO evidence code guide</a></p> Inferred from direct assayⁱ
  • Ref.4

    "Pgt1, a glutathione transporter from the fission yeast Schizosaccharomyces pombe."
    Thakur A., Kaur J., Bachhawat A.K.
    FEMS Yeast Res. 8:916-929(2008) [PubMed] [Europe PMC] [Abstract]

    Cited for: FUNCTION, BIOPHYSICOCHEMICAL PROPERTIES, INDUCTION, SUBCELLULAR LOCATION.
• oligopeptide transmembrane transporter activity Source: GO_Central <p>Inferred from Biological aspect of Ancestor</p> <p>A type of phylogenetic evidence whereby an aspect of a descendent is inferred through the characterization of an aspect of a ancestral gene.</p> <p>More information in the <a href="http://geneontology.org/page/guide%2Dgo%2Devidence%2Dcodes#iba">GO evidence code guide</a></p> Inferred from biological aspect of ancestorⁱ
  • "Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium."
    Gaudet P., Livstone M.S., Lewis S.E., Thomas P.D.
    Brief Bioinform 12:449-462(2011) [PubMed] [Europe PMC] [Abstract]

GO - Biological processⁱ

• glutathione import across plasma membrane Source: PomBaseInferred from direct assayⁱ
  • Ref.4

    "Pgt1, a glutathione transporter from the fission yeast Schizosaccharomyces pombe."
    Thakur A., Kaur J., Bachhawat A.K.
    FEMS Yeast Res. 8:916-929(2008) [PubMed] [Europe PMC] [Abstract]

    Cited for: FUNCTION, BIOPHYSICOCHEMICAL PROPERTIES, INDUCTION, SUBCELLULAR LOCATION.
• glutathione transmembrane transport Source: PomBaseInferred from direct assayⁱ
  • Ref.4

    "Pgt1, a glutathione transporter from the fission yeast Schizosaccharomyces pombe."
    Thakur A., Kaur J., Bachhawat A.K.
    FEMS Yeast Res. 8:916-929(2008) [PubMed] [Europe PMC] [Abstract]

    Cited for: FUNCTION, BIOPHYSICOCHEMICAL PROPERTIES, INDUCTION, SUBCELLULAR LOCATION.
• protein transport Source: UniProtKB-KW

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsⁱ

Protein family/group databases

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyⁱ

Organism-specific databases

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationⁱ

Topology

Keywords - Cellular componentⁱ

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingⁱ

Molecule processing

Amino acid modifications

Keywords - PTMⁱ

Proteomic databases

PTM databases

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressionⁱ

<p>This subsection of the 'Expression' section reports the experimentally proven effects of inducers and repressors (usually chemical compounds or environmental factors) on the level of protein (or mRNA) expression (up-regulation, down-regulation, constitutive expression).<p><a href='/help/induction' target='_top'>More...</a></p>Inductionⁱ

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactionⁱ

Protein-protein interaction databases

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsⁱ

Coiled coil

<p>This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesⁱ

Keywords - Domainⁱ

Phylogenomic databases

Family and domain databases

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequenceⁱ

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusⁱ: Complete.

        10         20         30         40         50
MTARNSASIP TSIRKTSENE VSGDETPAGV GNLSTKTASK TSLTFRQSSS 
        60         70         80         90        100
DESTSSYSGN HHNINIQHHP NRPFRTNSSS FSPNDYSISE SPSKSKKDGV 
       110        120        130        140        150
HVSAVQLDNE TDSEVESEVE ELERELEAIE DSVYPEVRAA VNPTDDVNLP 
       160        170        180        190        200
VNTWRTWVLT TIFVIVFAAV NQFFSLRYPA LSISFIVAQL ILFPLGKLLN 
       210        220        230        240        250
LLPNWKIGYG RFSFYLNSSP FNVKEHAAIT IAVSLTSSTA YATNILSAQT 
       260        270        280        290        300
SFYKQNLSWG YKILIVLTSQ MLGYGFAGLT RRWIVYPAAM IWPQTLVSTV 
       310        320        330        340        350
LFRTLHGNSG NDIGVLKNNR ISANGWTISR YRFFAYVMIG SFVFYWFPGF 
       360        370        380        390        400
IFKGLSYFTV LCWIWPKNRV VNQLFGYNSG LGILPLTFDW QQVVYNSNPL 
       410        420        430        440        450
ASPWWVICNT FGSVVLIFWI VVPILYYKGV WFSNYLPMLS SSTFDHTGVS 
       460        470        480        490        500
YNSSRVLNSD YSFNHTKYES YSPLYMPMSY SMSTALNFAA VTAIFTHCAL 
       510        520        530        540        550
YNGKDIWQRL WKESGKDECI HRKLMRNYKE APQWWYATLF IVVFGLTIFT 
       560        570        580        590        600
VRYYDTQCPV WALIVALLIF IVNFIPQGVL EGITNQHVGL NIITELIGGY 
       610        620        630        640        650
ILPGKPLANL MIKLYGFIPM RQGLEFSRDL KLAQYMKIPP RILFFVQLFA 
       660        670        680        690        700
TILGGITQVA VQEWMNYHIP GICTTSQSNG FTCPNGRSIY NASLIWGAIG 
       710        720        730        740        750
PAKMFSKGKP YYPLIFFFLI GAVAPFITWG LRKRFPKSWI GKLNAPVLFT 
       760        770        780        790        800
GPGNIPPATG INYSSWAIVG FIFNYVIRKR AIHWWRKYNY VLAAAMDSGV 
       810        820        830        840        850
AVAGVVIFLC VSYPGGKITW WGNTVYTKTY DWKSVPYRSL GPNETFGYTN 

W                                                      

Sequence databases

Genome annotation databases

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsⁱ

• 50% Identity

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesⁱ

Sequence databases

3D structure databases

Protein-protein interaction databases

Protein family/group databases

PTM databases

Proteomic databases

Genome annotation databases

Organism-specific databases

Phylogenomic databases

Miscellaneous databases

Family and domain databases

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationⁱ

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousⁱ

Keywords - Technical termⁱ

Documents

1. Schizosaccharomyces pombe
   Schizosaccharomyces pombe: entries and gene names
2. SIMILARITY comments
   Index of protein domains and families