tsr1

Functionⁱ

Required for 40S ribosomal subunit synthesis. Required for normal export of the pre-40S particles from the nucleus to the cytoplasm (By similarity).By similarity

GO - Molecular functionⁱ

GTPase activity Source: GO_Central
GTP binding Source: GO_Central
U3 snoRNA binding Source: GO_Central

View the complete GO annotation on QuickGO ...

GO - Biological processⁱ

endonucleolytic cleavage of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) Source: GO_Central
maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) Source: GO_Central
rRNA processing Source: PomBase

View the complete GO annotation on QuickGO ...

Keywordsⁱ

Biological process	Ribosome biogenesis

Biological process

Ribosome biogenesis

Names & Taxonomyⁱ

Protein namesⁱ	Recommended name: Ribosome biogenesis protein tsr1
Gene namesⁱ	Name:tsr1 ORF Names:SPAC23H4.15
Organismⁱ	Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Taxonomic identifierⁱ	284812 [NCBI]
Taxonomic lineageⁱ	cellular organisms › Eukaryota › Opisthokonta › Fungi › Dikarya › Ascomycota › Taphrinomycotina › Schizosaccharomycetes › Schizosaccharomycetales › Schizosaccharomycetaceae › Schizosaccharomyces › Schizosaccharomyces pombe
Proteomesⁱ	UP000002485 Componentⁱ: Chromosome I

Organism-specific databases

EuPathDBⁱ	FungiDB:SPAC23H4.15
PomBaseⁱ	SPAC23H4.15 tsr1

Keywords - Cellular componentⁱ

Cytoplasm, Nucleus

PTM / Processingⁱ

Molecule processing

Feature key	Position(s)	DescriptionActions	Graphical view	Length
ChainⁱPRO_0000339127	1 – 783	Ribosome biogenesis protein tsr1Add BLAST		783

Proteomic databases

MaxQB - The MaxQuant DataBase More...MaxQBⁱ	O13956
PaxDbⁱ	O13956
PRIDEⁱ	O13956

PTM databases

iPTMnetⁱ	O13956

iPTMnetⁱ

O13956

Interactionⁱ

Protein-protein interaction databases

STRINGⁱ	4896.SPAC23H4.15.1

STRINGⁱ

4896.SPAC23H4.15.1

Family & Domainsⁱ

Domains and Repeats

Feature key	Position(s)	DescriptionActions	Graphical view	Length
Domainⁱ	80 – 249	Bms1-type GAdd BLAST		170

Compositional bias

Feature key	Position(s)	DescriptionActions	Graphical view	Length
Compositional biasⁱ	396 – 488	Glu-richAdd BLAST		93

Sequence similaritiesⁱ

Belongs to the TRAFAC class translation factor GTPase superfamily. Bms1-like GTPase family. TSR1 subfamily.Curated

Phylogenomic databases

HOGENOMⁱ	HOG000165026
InParanoidⁱ	O13956
KEGG Orthology (KO) More...KOⁱ	K14799
OMAⁱ	YFKATFD
Database of Orthologous Groups More...OrthoDBⁱ	EOG092C16GO
PhylomeDBⁱ	O13956

Family and domain databases

InterProⁱ	View protein in InterPro IPR012948 AARP2CN IPR007034 BMS1_TSR1_C IPR030387 G_Bms1/Tsr1_dom
Pfam protein domain database More...Pfamⁱ	View protein in Pfam PF08142 AARP2CN, 1 hit PF04950 RIBIOP_C, 1 hit
SMARTⁱ	View protein in SMART SM00785 AARP2CN, 1 hit SM01362 DUF663, 1 hit
PROSITEⁱ	View protein in PROSITE PS51714 G_BMS1, 1 hit

Sequenceⁱ

Sequence statusⁱ: Complete.

O13956-1 [UniParc]FASTA Add to basket

« Hide

        10         20         30         40         50
MAHHHRSTFK AKKPFKSKHA SKSSLKEKYK NEVEPHRSGP KNIVHTSTKA 
        60         70         80         90        100
DRRNTAKQIQ LNKRTEVAMN NRIFGGKNGA PKVITIVPLC NNVDSWNVLT 
       110        120        130        140        150
NLLRSIDPEA SLPKFDKDSI SYSTTIDRFK QNLLFLLPKR EFYSLIDACK 
       160        170        180        190        200
VSDYVIFVLS AVQEVDEFGE LIVRTTQGQG ISSVLSMVHD LSEVDSLKTR 
       210        220        230        240        250
NEVKKSLQSF MNFFFSDQER VFAADVSQDA LNVMRALCTS HPRGIHWRDS 
       260        270        280        290        300
RSYLLSQEIS YSNGNLLVRG IVRGKGLDPN RLIHIQGFGD FAINRIYEAP 
       310        320        330        340        350
QGIQNSRGIS MDEDTNLTGG LVELCSPTQE QDSLESLGPI IDDMDTDMDS 
       360        370        380        390        400
EVGKEASRGV RLDDFYYFDD EEEPVAVAKR VPKGTSTYQA TWIPDEDEES 
       410        420        430        440        450
DQYSDVEDTE VIIEDQDNQE ISNHVAEEKI DSDEEETIDD AKSEMFVDLS 
       460        470        480        490        500
EEEEVRQYEE YRKKQKELQE ELEFPDEVEL QPNELARERF KKYRGLRSLY 
       510        520        530        540        550
TSQWDADEYD PNEPREWRQL FKFENYRNLK NKFLKQPFIG EAKPGKAVYV 
       560        570        580        590        600
ELRNVPIEIF EYYNKPWNLL VLYSLLQYEN KLTVSQFTAM QHSEYEEPIE 
       610        620        630        640        650
SKEELLLQIG PRRFMVRPLY SDPTASGASN NLQKYHRYLP PKQAVIASVI 
       660        670        680        690        700
SPIVFGNVPI IMFKKSSDNS LRLAATGSYV NCDTNSVIAK RAVLTGHPFK 
       710        720        730        740        750
VHKKLVTIRY MFFNPEDVIW FKPIQLFTKQ GRTGYIKEPL GTHGYFKATF 
       760        770        780 
NGKITVQDTV AMSLYKRMYP LPCELFKVTD IDS

Length:783

Mass (Da):90,126

Last modified:January 1, 1998 - v1

Checksum:ⁱ67BDC6EC0AA7D346

GO

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	CU329670 Genomic DNA Translation: CAB11669.1
PIRⁱ	T38313
NCBI Reference Sequences More...RefSeqⁱ	NP_593391.1, NM_001018823.2

Genome annotation databases

EnsemblFungiⁱ	SPAC23H4.15.1; SPAC23H4.15.1:pep; SPAC23H4.15
GeneIDⁱ	2541779
KEGGⁱ	spo:SPAC23H4.15

Similar proteinsⁱ

50% Identity

Protein	Similar proteins		Species	Score	Length	Source
O13956	Ribosome biogenesis protein Tsr1		SCHCR		776	UniRef50_O13956
Ribosome biogenesis protein Tsr1		SCHJY		774
Ribosome biogenesis protein Tsr1		SCHOY		778

Cross-referencesⁱ

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	CU329670 Genomic DNA Translation: CAB11669.1
PIRⁱ	T38313
RefSeqⁱ	NP_593391.1, NM_001018823.2

3D structure databases

ModBaseⁱ	Search...
MobiDBⁱ	Search...

Protein-protein interaction databases

STRINGⁱ	4896.SPAC23H4.15.1

STRINGⁱ

4896.SPAC23H4.15.1

PTM databases

iPTMnetⁱ	O13956

iPTMnetⁱ

O13956

Proteomic databases

MaxQBⁱ	O13956
PaxDbⁱ	O13956
PRIDEⁱ	O13956

Protocols and materials databases

Structural Biology Knowledgebase	Search...

Structural Biology Knowledgebase

Search...

Genome annotation databases

EnsemblFungiⁱ	SPAC23H4.15.1; SPAC23H4.15.1:pep; SPAC23H4.15
GeneIDⁱ	2541779
KEGGⁱ	spo:SPAC23H4.15

Organism-specific databases

EuPathDBⁱ	FungiDB:SPAC23H4.15
PomBaseⁱ	SPAC23H4.15 tsr1

Phylogenomic databases

HOGENOMⁱ	HOG000165026
InParanoidⁱ	O13956
KOⁱ	K14799
OMAⁱ	YFKATFD
OrthoDBⁱ	EOG092C16GO
PhylomeDBⁱ	O13956

Miscellaneous databases

Protein Ontology More...PROⁱ	PR:O13956

PROⁱ

PR:O13956

Family and domain databases

InterProⁱ	View protein in InterPro IPR012948 AARP2CN IPR007034 BMS1_TSR1_C IPR030387 G_Bms1/Tsr1_dom
Pfamⁱ	View protein in Pfam PF08142 AARP2CN, 1 hit PF04950 RIBIOP_C, 1 hit
SMARTⁱ	View protein in SMART SM00785 AARP2CN, 1 hit SM01362 DUF663, 1 hit
PROSITEⁱ	View protein in PROSITE PS51714 G_BMS1, 1 hit
ProtoNetⁱ	Search...

Entry informationⁱ

Entry nameⁱ	TSR1_SCHPO
Accessionⁱ	O13956Primary (citable) accession number: O13956
Entry historyⁱ	Integrated into UniProtKB/Swiss-Prot:	June 10, 2008
	Last sequence update:	January 1, 1998
	Last modified:	June 20, 2018
	This is version 94 of the entry and version 1 of the sequence. See complete history.
Entry statusⁱ	Reviewed (UniProtKB/Swiss-Prot)
Annotation program	Fungal Protein Annotation Program

UniProtKB

UniParc

Help

UniRef

Proteomes

Annotation systems

Supporting data

UniProtKB - O13956 (TSR1_SCHPO)

Your basket is currently empty. i <p>When browsing through different UniProt proteins, you can use the ‘basket’ to save them, so that you can back to find or analyse them later.<p><a href='/help/basket' target='_top'>More...</a></p>

Ribosome biogenesis protein tsr1

Select a section on the left to see content.

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

Organism-specific databases

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Nucleus

Other locations

Nucleus

Other locations

Keywords - Cellular componenti

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Proteomic databases

PTM databases

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Compositional bias

<p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Phylogenomic databases

Family and domain databases

Sequence databases

Genome annotation databases

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

3D structure databases

Protein-protein interaction databases

PTM databases

Proteomic databases

Protocols and materials databases

Genome annotation databases

Organism-specific databases

Phylogenomic databases

Miscellaneous databases

Family and domain databases

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Documents

UniProt is an ELIXIR core data resource

Your basket is currently empty. ⁱ

Functionⁱ

GO - Molecular functionⁱ

GO - Biological processⁱ

Names & Taxonomyⁱ

Subcellular locationⁱ

Keywords - Cellular componentⁱ

PTM / Processingⁱ

Interactionⁱ

Family & Domainsⁱ

Sequence similaritiesⁱ

Cross-referencesⁱ

Entry informationⁱ

Miscellaneousⁱ

Keywords - Technical termⁱ