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Protein

Signal recognition particle receptor subunit beta

Gene

srp102

Organism
Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Component of the SRP (signal recognition particle) receptor. Ensures, in conjunction with the signal recognition particle, the correct targeting of the nascent secretory proteins to the endoplasmic reticulum membrane system. Has GTPase activity. May mediate the membrane association of SRPR (By similarity).By similarity

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Binding sitei87GTP; via amide nitrogenBy similarity1

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Nucleotide bindingi44 – 52GTPBy similarity9
Nucleotide bindingi65 – 68GTPBy similarity4

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionReceptor
LigandGTP-binding, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Signal recognition particle receptor subunit beta
Short name:
SR-beta
Gene namesi
Name:srp102
ORF Names:SPAC23H4.07c
OrganismiSchizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Taxonomic identifieri284812 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaTaphrinomycotinaSchizosaccharomycetesSchizosaccharomycetalesSchizosaccharomycetaceaeSchizosaccharomyces
Proteomesi
  • UP000002485 Componenti: Chromosome I

Organism-specific databases

EuPathDBiFungiDB:SPAC23H4.07c
PomBaseiSPAC23H4.07c srp102

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cell wall Cytoskeleton Vacuole Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei8 – 28HelicalSequence analysisAdd BLAST21

Keywords - Cellular componenti

Endoplasmic reticulum, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001012291 – 227Signal recognition particle receptor subunit betaAdd BLAST227

Proteomic databases

MaxQBiO13950
PaxDbiO13950
PRIDEiO13950

Interactioni

Subunit structurei

Heterodimer of an alpha and a beta chain.

Protein-protein interaction databases

STRINGi4896.SPAC23H4.07c.1

Structurei

3D structure databases

ProteinModelPortaliO13950
SMRiO13950
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the SRP receptor beta subunit family.Curated

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

InParanoidiO13950
KOiK12272
OMAiNKQDQTT
OrthoDBiEOG092C5BU6
PhylomeDBiO13950

Family and domain databases

CDDicd04105 SR_beta, 1 hit
InterProiView protein in InterPro
IPR027417 P-loop_NTPase
IPR019009 SRP_receptor_beta_su
PANTHERiPTHR11485:SF34 PTHR11485:SF34, 1 hit
PfamiView protein in Pfam
PF09439 SRPRB, 1 hit
SUPFAMiSSF52540 SSF52540, 1 hit

Sequencei

Sequence statusi: Complete.

O13950-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MDGTSQAFKI IVATIIIGAI ISTLGIFFTR KTIQKKLPAV FLIGPSDSGK
60 70 80 90 100
TSLFCELIYK EKKTTVPSIE PNEAVWKYGA WLVDLPGHPR AKRWITTKFS
110 120 130 140 150
GNYNVKAVVF VLNSATIDRD VHEVGLMLFD TILKCRKHHV PHLLIACNKF
160 170 180 190 200
DLFTAQPAEK IQQLLKAELH NILEEKNLQL ESIVSEDVDW ESVADQIEDT
210 220
DLKFLPGSVA KMSNIEEWIS WMESALQ
Length:227
Mass (Da):25,612
Last modified:January 1, 1998 - v1
Checksum:i814ED594E4F8C97F
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CU329670 Genomic DNA Translation: CAB11661.1
AB027896 Genomic DNA Translation: BAA87200.1
PIRiT38321
RefSeqiNP_593399.1, NM_001018831.2

Genome annotation databases

EnsemblFungiiSPAC23H4.07c.1; SPAC23H4.07c.1:pep; SPAC23H4.07c
GeneIDi2541760
KEGGispo:SPAC23H4.07c

Similar proteinsi

Entry informationi

Entry nameiSRPB_SCHPO
AccessioniPrimary (citable) accession number: O13950
Secondary accession number(s): Q9USB4
Entry historyiIntegrated into UniProtKB/Swiss-Prot: June 1, 2001
Last sequence update: January 1, 1998
Last modified: February 28, 2018
This is version 123 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Schizosaccharomyces pombe
    Schizosaccharomyces pombe: entries and gene names
  2. SIMILARITY comments
    Index of protein domains and families

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