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Entry version 136 (02 Jun 2021)
Sequence version 1 (01 Jan 1998)
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Protein

E3 ubiquitin-protein ligase ptr1

Gene

ptr1

Organism
Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Status
Reviewed-Annotation score:

Annotation score:4 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Probable ubiquitin ligase protein involved in mRNA export. E3 ubiquitin ligase proteins mediate ubiquitination and subsequent proteasomal degradation of target proteins. Probably participates in mRNA export from the nucleus by regulating the transport of hnRNP proteins such as rae1.

1 Publication

<p>This subsection of the <a href="http://www.uniprot.org/help/function_section">Function</a> section describes the catalytic activity of an enzyme, i.e. a chemical reaction that the enzyme catalyzes.<p><a href='/help/catalytic_activity' target='_top'>More...</a></p>Catalytic activityi

  • S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine. EC:2.3.2.26

<p>This subsection of the <a href="http://www.uniprot.org/help/function_section">'Function'</a> section describes the metabolic pathway(s) associated with a protein.<p><a href='/help/pathway' target='_top'>More...</a></p>Pathwayi: protein ubiquitination

This protein is involved in the pathway protein ubiquitination, which is part of Protein modification.
View all proteins of this organism that are known to be involved in the pathway protein ubiquitination and in Protein modification.

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/function_section">Function</a> section is used for enzymes and indicates the residues directly involved in catalysis.<p><a href='/help/act_site' target='_top'>More...</a></p>Active sitei3194Glycyl thioester intermediatePROSITE-ProRule annotation1

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionTransferase
Biological processmRNA transport, Transport, Ubl conjugation pathway

Enzyme and pathway databases

Reactome - a knowledgebase of biological pathways and processes

More...
Reactomei
R-SPO-6798695, Neutrophil degranulation
R-SPO-983168, Antigen processing: Ubiquitination & Proteasome degradation

UniPathway: a resource for the exploration and annotation of metabolic pathways

More...
UniPathwayi
UPA00143

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
E3 ubiquitin-protein ligase ptr1 (EC:2.3.2.26)
Alternative name(s):
HECT-type E3 ubiquitin transferase ptr1
Poly(A)+ RNA transport protein 1
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:ptr1
ORF Names:SPAC19D5.04
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiSchizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri284812 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaTaphrinomycotinaSchizosaccharomycetesSchizosaccharomycetalesSchizosaccharomycetaceaeSchizosaccharomyces
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000002485 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome I

Organism-specific databases

Schizosaccharomyces pombe database

More...
PomBasei
SPAC19D5.04, ptr1

Eukaryotic Pathogen, Vector and Host Database Resources

More...
VEuPathDBi
FungiDB:SPAC19D5.04

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Keywords - Cellular componenti

Nucleus

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Mutagenesis

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/manual/pathology_and_biotech_section">'Pathology and Biotech'</a> section describes the effect of the experimental mutation of one or more amino acid(s) on the biological properties of the protein.<p><a href='/help/mutagen' target='_top'>More...</a></p>Mutagenesisi2887L → Q in ptr1-1; induces defects in mRNA export. 1

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00001203471 – 3227E3 ubiquitin-protein ligase ptr1Add BLAST3227

Proteomic databases

MaxQB - The MaxQuant DataBase

More...
MaxQBi
O13834

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
O13834

PRoteomics IDEntifications database

More...
PRIDEi
O13834

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
O13834

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGRID)

More...
BioGRIDi
278994, 8 interactors

STRING: functional protein association networks

More...
STRINGi
4896.SPAC19D5.04.1

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
O13834

Database of comparative protein structure models

More...
ModBasei
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family_and_domains_section">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini2891 – 3227HECTPROSITE-ProRule annotationAdd BLAST337

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni1806 – 1836DisorderedSequence analysisAdd BLAST31
Regioni1869 – 1894DisorderedSequence analysisAdd BLAST26
Regioni1908 – 1929DisorderedSequence analysisAdd BLAST22
Regioni2577 – 2607DisorderedSequence analysisAdd BLAST31

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes the position of regions of compositional bias within the protein and the particular type of amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi1806 – 1823Polar residuesSequence analysisAdd BLAST18
Compositional biasi2577 – 2598Polar residuesSequence analysisAdd BLAST22

<p>This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the UPL family. TOM1/PTR1 subfamily.Curated

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG0939, Eukaryota

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
CLU_000215_0_1_1

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
O13834

Identification of Orthologs from Complete Genome Data

More...
OMAi
HGLLFQI

Database for complete collections of gene phylogenies

More...
PhylomeDBi
O13834

Family and domain databases

Conserved Domains Database

More...
CDDi
cd00078, HECTc, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR010309, E3_Ub_ligase_DUF908
IPR010314, E3_Ub_ligase_DUF913
IPR000569, HECT_dom
IPR035983, Hect_E3_ubiquitin_ligase
IPR025527, HUWE1/Rev1_UBM

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF06012, DUF908, 1 hit
PF06025, DUF913, 1 hit
PF00632, HECT, 1 hit
PF14377, UBM, 2 hits

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00119, HECTc, 1 hit

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF56204, SSF56204, 1 hit

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS50237, HECT, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

O13834-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MRITKSPPKN QYSQPPPRVA EFIRQAQNEE VTSDLGLVSL CSEFRKNDWP
60 70 80 90 100
YPRGDLYSWV PVLNRFDAIL ERIVEHYSLK DKVQTKPFDS DTLSILLEIL
110 120 130 140 150
SFSAHLLSHC ANRSIYNSTV YLEYLLNSSV LEVIDSTLAL LLHIVQKATI
160 170 180 190 200
SKRGKQLFSL SQDRLFRFLM FLPQDAMKTG FSQNYETLLF SNEIPQEWCS
210 220 230 240 250
LELSYYKSSP SKDFSSASQP NSEGFSILKL PYNKVLGKPI EELLVKTLHD
260 270 280 290 300
NQIPEQYSFD LLVSLMLRQN LYDINRRRLM IRIGLLALSN LVYAHSQAVQ
310 320 330 340 350
TRFLIADPEI TTHLANLVSP DVDLPQNFKA VCFECFKAFF FKKSMIPSVL
360 370 380 390 400
ASLNVSVSYG LMMNLVRDFS KNLENPNFYY EREYVDSFYD FLQFMTSSPL
410 420 430 440 450
GGNMACSAGL TSLLGYHLSV KTPQATYVVA RSIVMLDHLI DGYSMAFPDF
460 470 480 490 500
SESKGLDMLV DRVQYELEAG LQDIKSGKGN PEIVLNMDYA ISYDRYFLLK
510 520 530 540 550
NLLKFVLHLI QSGGSVVELR NLIDSSLISS LAFLLEHHEV YGSNLFASTT
560 570 580 590 600
NIMSTFIHNE PTCYGIIHEK KLSHAFLDAV NRKILNSSDA ITSIPLAFGA
610 620 630 640 650
ICLNSQGFDL FLEKNPIPQL FSIFTSLNHC KSLISSDNAA ILGTYIDELM
660 670 680 690 700
RHQPSLKDPI VKMIFKACDQ VSALLDNFNP FQYINAKEYP YLLYLETFSS
710 720 730 740 750
FLENIITNEG HARYLISKGI VSHVLNLIQH PVLAFGFIDS SAFNSFFVLL
760 770 780 790 800
HHAVDFDAPE VFRPLLDCII TRCEEGITEF TIVSLKQATI SLIKDSNMGH
810 820 830 840 850
EDANNFLHFS IVGNLLTIFA ELFSSHAALK KAGNLPLVQL FISPSRYAGI
860 870 880 890 900
FDILCNIKSI ATSLDIHICL GVSDDFVLCS DSLTTIVTDK DEKEKFETKK
910 920 930 940 950
KELTQDSSFC KFQNIRSNFS QIAYGVSKFF TSLTRALGNT SVQDFNEYKM
960 970 980 990 1000
IHKLGSNIAL VVDELINLSS KQITSHPQSL SIASLEASLI FVLGASSIIR
1010 1020 1030 1040 1050
EDDSKVTLVL LISRLLGGCR TMDVLISLNE TVSGFFRLSD RDPLSKSNRV
1060 1070 1080 1090 1100
LLALSSTLLN LILVFTSADF MSETSKTLNM ALKSEFDMTD FNNSGSKLMH
1110 1120 1130 1140 1150
VLHARIFISV LHLWRSADDL HLPYITRALL TNVLSNCYQF EDGIKNVVDS
1160 1170 1180 1190 1200
INNLRTSIAN GDIKEPLDVV TDDNTNSNFS LEETNASVTD MPESEKHENG
1210 1220 1230 1240 1250
IFQAYLLKEM PNDIVSQFEM LKSKQIELTV QMASYEGDLN QNLCDFLYTR
1260 1270 1280 1290 1300
DDVQMNADVQ FSVTSGLIVE IKKLAQSTDC KAKNQLGPAV GLLSLFISHD
1310 1320 1330 1340 1350
FTQNKAKNCV LSELNFFLEL LHSLNNGLPS DSHKTSIVCI LYLLEVLLAD
1360 1370 1380 1390 1400
SKKPDEFEFN SEDCSLKLTD GAITVDLASQ KHIMSSVITL LSLNSANLGV
1410 1420 1430 1440 1450
VVSAFRVVVL LTSASEMIHT FVKLSGLPSL FKAMRACSGF CNESLHIPFI
1460 1470 1480 1490 1500
SILRRLLEFD EVVELMMFDD LVNIFKLQGR ARKTELHGFI RANAEMVLRS
1510 1520 1530 1540 1550
PECFIKILKD CCVLGHFTPE SEHYYLELKE SLPGVLQNGQ TDLDPSKEQM
1560 1570 1580 1590 1600
SSVIVSFLLD ELMDLTETRQ FSDRSPNSEF TPENDSLYMY NVFLLQCLTE
1610 1620 1630 1640 1650
LLSGYNACKR CFLNFQPRRK APFFNLSRKY NSYLVGFFLE KLLPFGCIRL
1660 1670 1680 1690 1700
SENNEVRKAF SVSNWAISIL VFLCAYSNEQ QTQAVDEIRR EVLTSVLKFY
1710 1720 1730 1740 1750
KSSSSFSENL EAYYCKLLVL AELCYRLCDA QTVSQKAPNH LLRRSQDQNV
1760 1770 1780 1790 1800
KTMIDLGYIP TLTNAISEID MNYPVSRKVV RHILKPLQLL TKEAIFLSQT
1810 1820 1830 1840 1850
NPEALSGAAQ DSMGDQSLSS SSEESSDSDR EEPPDLYRNS VLGIFQGDIV
1860 1870 1880 1890 1900
NENDENYEDS EDDGVYEEME FEDDQSGSAD SVVSEDDADD VMYSDNDDMN
1910 1920 1930 1940 1950
IEFMVDEQDA SSQNDDSSFD EASSHGDVIS IDEEDLDNQG EEFEWEDEDN
1960 1970 1980 1990 2000
ASSGYEDELD YNEDEVGEND STTFEAMENA FTETSDNDDH LEEADHVSPV
2010 2020 2030 2040 2050
EIDFLENDEN SSSEQDDEFQ WEWNTETPSG ADILSRHGAL LRDLFPLPGL
2060 2070 2080 2090 2100
SRRVMIINSN DPSRSRPFLN NNASEGLLKH PLLLRNNLIH TPKATELWEN
2110 2120 2130 2140 2150
LAEIDNHTAS GAAFQRLLYY LALEIPNEDS SVLGWTSLKV SKHTDPLRAT
2160 2170 2180 2190 2200
SDFIPLFSMQ RWNSITSMFF AHASGSIALR ITGSVLFALV PPALEKYNLE
2210 2220 2230 2240 2250
NQKKEILENE SKEEETRQPE VNIQPEEPIN TSDMEGVTTE ANEIGSYQEP
2260 2270 2280 2290 2300
SLINIRGREV DVSSLGIDPT FLLALPEEMR EEVVFQHIQE RHMESISDSS
2310 2320 2330 2340 2350
RRIDPSFLEV LPSDLRDELL FQEAVQMRLF DHATRNNNSV DHEVEMEEID
2360 2370 2380 2390 2400
QGGTVSEHRE KSVKPVKKIP VPNLLDRQGL YSLIRLIFIS QHNGKNPYYD
2410 2420 2430 2440 2450
LIVNISENKQ HRADIVGLLL YILQEASIND RASEKCYRDL TVKSLNNSQQ
2460 2470 2480 2490 2500
KEVKKSTGLL ESLCKVPVVN GISAPALILQ QGIDLLSHLA TWADHFASFF
2510 2520 2530 2540 2550
LSMHDFSGIA SKKSAGRKNR ESNVYKIAPI NVLLGLLARE ELFGNTLVMN
2560 2570 2580 2590 2600
TFSELLSTLT KPLLSFYKSE KLQKDSATTG YTNDQDSRGS TVPKQDPGTT
2610 2620 2630 2640 2650
ASRKDKKILS PPNILDENLR LAASLITTDS CSSRTFQNAL SVMFHLSSIP
2660 2670 2680 2690 2700
KAKILIGKEL LRHGQEYGNS ITNDLSRLCA DVKSGKNESE LQVALAPFCP
2710 2720 2730 2740 2750
ASSNQAKLLR CLKALDYIFE RRPKGQEQSP GNIIQLLEFY DNLKFSSLWE
2760 2770 2780 2790 2800
VLSECLSALR DHTSITHVST VLLPLIESLM VICRLVFIEL PEDVGKHISP
2810 2820 2830 2840 2850
ILERFKTLFI SFTEEHRKII NMMVFTTPSL MSGSFSLLVK NPKVLEFENK
2860 2870 2880 2890 2900
RNYFNRQLHE EAAKEQYPPL NITVRRDHVF LDSYRALHFK DADEVKFSKL
2910 2920 2930 2940 2950
NIHFRDEEGV DAGGVTREWL QVLARQMFNP DYALFLPVTG DATTFHPNRD
2960 2970 2980 2990 3000
SSVNPDHLSF FKFTGRIIGK ALYDGRLLDC HFSRAVYKHM LHRSVSVKDI
3010 3020 3030 3040 3050
ESLDPDYYKS LVWMLNNDIT DIITEEFAVE KDVFGEKTVV DLIPNGRNIP
3060 3070 3080 3090 3100
VTELNKQNYV NRMVDYKLRE SVKDQLKSLL DGFSDIIPSH LIQIFNEQEL
3110 3120 3130 3140 3150
ELLISGLPEI DIDDWKNNTE YHGYNVSSPQ VQWFWRAVRS FDEEERAKLL
3160 3170 3180 3190 3200
QFATGTSKVP LNGFKELEGM SGFQRFNIHK SYGSLNRLPQ SHTCFNQLDL
3210 3220
PEYDTYEQLR SMLLTAINEG SEGFGFA
Length:3,227
Mass (Da):365,035
Last modified:January 1, 1998 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i07FC47AB79124575
GO

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
CU329670 Genomic DNA Translation: CAB16714.1

Protein sequence database of the Protein Information Resource

More...
PIRi
T37964

NCBI Reference Sequences

More...
RefSeqi
NP_594902.1, NM_001020331.2

Genome annotation databases

Ensembl fungal genome annotation project

More...
EnsemblFungii
SPAC19D5.04.1; SPAC19D5.04.1:pep; SPAC19D5.04

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
2542537

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
spo:SPAC19D5.04

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CU329670 Genomic DNA Translation: CAB16714.1
PIRiT37964
RefSeqiNP_594902.1, NM_001020331.2

3D structure databases

SMRiO13834
ModBaseiSearch...

Protein-protein interaction databases

BioGRIDi278994, 8 interactors
STRINGi4896.SPAC19D5.04.1

PTM databases

iPTMnetiO13834

Proteomic databases

MaxQBiO13834
PaxDbiO13834
PRIDEiO13834

Genome annotation databases

EnsemblFungiiSPAC19D5.04.1; SPAC19D5.04.1:pep; SPAC19D5.04
GeneIDi2542537
KEGGispo:SPAC19D5.04

Organism-specific databases

PomBaseiSPAC19D5.04, ptr1
VEuPathDBiFungiDB:SPAC19D5.04

Phylogenomic databases

eggNOGiKOG0939, Eukaryota
HOGENOMiCLU_000215_0_1_1
InParanoidiO13834
OMAiHGLLFQI
PhylomeDBiO13834

Enzyme and pathway databases

UniPathwayiUPA00143
ReactomeiR-SPO-6798695, Neutrophil degranulation
R-SPO-983168, Antigen processing: Ubiquitination & Proteasome degradation

Miscellaneous databases

Protein Ontology

More...
PROi
PR:O13834

Family and domain databases

CDDicd00078, HECTc, 1 hit
InterProiView protein in InterPro
IPR010309, E3_Ub_ligase_DUF908
IPR010314, E3_Ub_ligase_DUF913
IPR000569, HECT_dom
IPR035983, Hect_E3_ubiquitin_ligase
IPR025527, HUWE1/Rev1_UBM
PfamiView protein in Pfam
PF06012, DUF908, 1 hit
PF06025, DUF913, 1 hit
PF00632, HECT, 1 hit
PF14377, UBM, 2 hits
SMARTiView protein in SMART
SM00119, HECTc, 1 hit
SUPFAMiSSF56204, SSF56204, 1 hit
PROSITEiView protein in PROSITE
PS50237, HECT, 1 hit

MobiDB: a database of protein disorder and mobility annotations

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<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiPTR1_SCHPO
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: O13834
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: July 19, 2004
Last sequence update: January 1, 1998
Last modified: June 2, 2021
This is version 136 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteome

Documents

  1. Schizosaccharomyces pombe
    Schizosaccharomyces pombe: entries and gene names
  2. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  3. SIMILARITY comments
    Index of protein domains and families
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