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Entry version 122 (29 Sep 2021)
Sequence version 1 (01 Jan 1998)
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Protein

PH and SEC7 domain-containing protein C11E3.11c

Gene

SPAC11E3.11c

Organism
Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Status
Reviewed-Annotation score:

Annotation score:3 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Protein predictedi <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

Enzyme and pathway databases

Reactome - a knowledgebase of biological pathways and processes

More...
Reactomei
R-SPO-6811438, Intra-Golgi traffic

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
PH and SEC7 domain-containing protein C11E3.11c
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
ORF Names:SPAC11E3.11c
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiSchizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri284812 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaTaphrinomycotinaSchizosaccharomycetesSchizosaccharomycetalesSchizosaccharomycetaceaeSchizosaccharomyces
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000002485 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome I

Organism-specific databases

Schizosaccharomyces pombe database

More...
PomBasei
SPAC11E3.11c

Eukaryotic Pathogen, Vector and Host Database Resources

More...
VEuPathDBi
FungiDB:SPAC11E3.11c

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00003171531 – 942PH and SEC7 domain-containing protein C11E3.11cAdd BLAST942

Proteomic databases

MaxQB - The MaxQuant DataBase

More...
MaxQBi
O13690

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
O13690

PRoteomics IDEntifications database

More...
PRIDEi
O13690

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
O13690

SwissPalm database of S-palmitoylation events

More...
SwissPalmi
O13690

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGRID)

More...
BioGRIDi
278276, 4 interactors

STRING: functional protein association networks

More...
STRINGi
4896.SPAC11E3.11c.1

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
O13690

Database of comparative protein structure models

More...
ModBasei
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family_and_domains_section">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini295 – 497SEC7PROSITE-ProRule annotationAdd BLAST203
Domaini681 – 804PHPROSITE-ProRule annotationAdd BLAST124

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni1 – 128DisorderedSequence analysisAdd BLAST128
Regioni259 – 308DisorderedSequence analysisAdd BLAST50

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes the position of regions of compositional bias within the protein and the particular type of amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi1 – 74Polar residuesSequence analysisAdd BLAST74
Compositional biasi88 – 125Polar residuesSequence analysisAdd BLAST38
Compositional biasi288 – 308Polar residuesSequence analysisAdd BLAST21

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG0929, Eukaryota

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
CLU_323935_0_0_1

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
O13690

Identification of Orthologs from Complete Genome Data

More...
OMAi
CHIVLFS

Database for complete collections of gene phylogenies

More...
PhylomeDBi
O13690

Family and domain databases

Conserved Domains Database

More...
CDDi
cd00171, Sec7, 1 hit

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
1.10.1000.11, 1 hit
2.30.29.30, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR011993, PH-like_dom_sf
IPR041681, PH_9
IPR001849, PH_domain
IPR023394, Sec7_C_sf
IPR000904, Sec7_dom
IPR035999, Sec7_dom_sf

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF15410, PH_9, 1 hit
PF01369, Sec7, 1 hit

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00233, PH, 1 hit
SM00222, Sec7, 1 hit

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF48425, SSF48425, 1 hit

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS50003, PH_DOMAIN, 1 hit
PS50190, SEC7, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

O13690-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MSRNASNAYL KNGNSTPSND KRSPSSLSQR SKTSTRSSKP FLQRLFPSTW
60 70 80 90 100
FKNESSSRHP LTSIKENDTQ TIGRRPSMRV KLFGKDKSKA SMSTNDLPSH
110 120 130 140 150
PRSQSVMGFS SSTSQLTGTS NSSRTRLNKD MRRDFGMTSM SSITSSTPTP
160 170 180 190 200
SQLPVRPSTS LSFFDDIPLG PSFSAETILS SLSISTSNNA MSKTTPAPPL
210 220 230 240 250
VTTKSISADQ DDFYTCKEEV STYEGLNSQI ELSPVKSRDS QNKSAKNLST
260 270 280 290 300
AYRTVSGESR NLMVDPKVSP YGNSRTPLRD SSNYLRDRRS INRQSSLSIP
310 320 330 340 350
KSTSETTRKT LALSNGGIDQ SRVSSDSFKV DDSSAKMAAI DIWEGSQHIV
360 370 380 390 400
SNDKALSWLV TDKPYNKAVL KHYISLYDFE NTDILQSLRM ICGNLYVHGE
410 420 430 440 450
TQELDHFLGE FSNQWCRTNP KGLFCNPQIV HSIAFSLLLL NTDLHIAELS
460 470 480 490 500
ASERMSRNQF VENTYRSIKQ ALNDSFDGNE EKKNAFFLSS YKSFASNESC
510 520 530 540 550
NSPAIHSLHG NLSPGKSAEL KKLHKRSLSS KVLEEAFSSY WMSALKEMYH
560 570 580 590 600
SIKVSMILQP DRYLDMNFDF NDTNKINNPS STANQTRHFH SVSEIKKLPM
610 620 630 640 650
GTDELEKSMV RPSTAMYINR QNENAVSIDK SRDLQGTVNT KEIRSRSALS
660 670 680 690 700
YQNDRPLATD LPSVIYNHKH PNVVSPFYVH PYIKQGILKF QSKESHKFRK
710 720 730 740 750
KEVWSTVLAV LQRDVFTLYN LNTPNLSYDP KDLDISKVGK PVIKTTIIAS
760 770 780 790 800
LAKPFPSSED AVVLKSTNSL YFDLETSSQL KLRFAGPSPK DAQGWIDALN
810 820 830 840 850
YWAARSSKVP LLGGVTNVDY GWARCTGQRA QKSNAQLLKT KTDKIIVHKW
860 870 880 890 900
QPQPVNTIPS SLSLGEQLSA FNNFMKLLKK TNDEHQNLHK EMLVVLSSQP
910 920 930 940
KSTFRRAVEN WKYKSDYLQL NLVRLRVYIS VLEKYKSQAQ NS
Length:942
Mass (Da):105,909
Last modified:January 1, 1998 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iA677CE2E619ECDF4
GO

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

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EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
CU329670 Genomic DNA Translation: CAB11190.1

Protein sequence database of the Protein Information Resource

More...
PIRi
T37539

NCBI Reference Sequences

More...
RefSeqi
NP_594936.1, NM_001020367.2

Genome annotation databases

Ensembl fungal genome annotation project

More...
EnsemblFungii
SPAC11E3.11c.1; SPAC11E3.11c.1:pep; SPAC11E3.11c

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
2541783

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
spo:SPAC11E3.11c

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CU329670 Genomic DNA Translation: CAB11190.1
PIRiT37539
RefSeqiNP_594936.1, NM_001020367.2

3D structure databases

SMRiO13690
ModBaseiSearch...

Protein-protein interaction databases

BioGRIDi278276, 4 interactors
STRINGi4896.SPAC11E3.11c.1

PTM databases

iPTMnetiO13690
SwissPalmiO13690

Proteomic databases

MaxQBiO13690
PaxDbiO13690
PRIDEiO13690

Genome annotation databases

EnsemblFungiiSPAC11E3.11c.1; SPAC11E3.11c.1:pep; SPAC11E3.11c
GeneIDi2541783
KEGGispo:SPAC11E3.11c

Organism-specific databases

PomBaseiSPAC11E3.11c
VEuPathDBiFungiDB:SPAC11E3.11c

Phylogenomic databases

eggNOGiKOG0929, Eukaryota
HOGENOMiCLU_323935_0_0_1
InParanoidiO13690
OMAiCHIVLFS
PhylomeDBiO13690

Enzyme and pathway databases

ReactomeiR-SPO-6811438, Intra-Golgi traffic

Miscellaneous databases

Protein Ontology

More...
PROi
PR:O13690

Family and domain databases

CDDicd00171, Sec7, 1 hit
Gene3Di1.10.1000.11, 1 hit
2.30.29.30, 1 hit
InterProiView protein in InterPro
IPR011993, PH-like_dom_sf
IPR041681, PH_9
IPR001849, PH_domain
IPR023394, Sec7_C_sf
IPR000904, Sec7_dom
IPR035999, Sec7_dom_sf
PfamiView protein in Pfam
PF15410, PH_9, 1 hit
PF01369, Sec7, 1 hit
SMARTiView protein in SMART
SM00233, PH, 1 hit
SM00222, Sec7, 1 hit
SUPFAMiSSF48425, SSF48425, 1 hit
PROSITEiView protein in PROSITE
PS50003, PH_DOMAIN, 1 hit
PS50190, SEC7, 1 hit

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiYDYB_SCHPO
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: O13690
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: February 5, 2008
Last sequence update: January 1, 1998
Last modified: September 29, 2021
This is version 122 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Technical termi

Reference proteome

Documents

  1. Schizosaccharomyces pombe
    Schizosaccharomyces pombe: entries and gene names
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