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Entry version 97 (31 Jul 2019)
Sequence version 3 (01 May 2000)
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Protein

Protein sfi1

Gene

sfi1

Organism
Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Status
Reviewed-Annotation score:

Annotation score:3 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Protein inferred from homologyi <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Component of the spindle pole body (SPB) half-bridge involved in the initial steps of SPB duplication.By similarity

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Biological processCell cycle, Cell division, Mitosis

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Protein sfi1
Alternative name(s):
Suppressor of fermentation induced loss of stress resistance protein 1
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:sfi1
ORF Names:pi059, SPBC8D2.05c
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiSchizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri284812 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaTaphrinomycotinaSchizosaccharomycetesSchizosaccharomycetalesSchizosaccharomycetaceaeSchizosaccharomyces
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000002485 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome II

Organism-specific databases

Eukaryotic Pathogen Database Resources

More...
EuPathDBi
FungiDB:SPBC8D2.05c

Schizosaccharomyces pombe database

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PomBasei
SPBC8D2.05c sfi1

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cell wall Cytoskeleton Vacuole Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

Keywords - Cellular componenti

Cytoplasm, Cytoskeleton, Nucleus

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00002906471 – 840Protein sfi1Add BLAST840

Proteomic databases

PaxDb, a database of protein abundance averages across all three domains of life

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PaxDbi
O13652

PRoteomics IDEntifications database

More...
PRIDEi
O13652

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
O13652

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGrid)

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BioGridi
277756, 2 interactors

Protein interaction database and analysis system

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IntActi
O13652, 3 interactors

Molecular INTeraction database

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MINTi
O13652

STRING: functional protein association networks

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STRINGi
4896.SPBC8D2.05c.1

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

<p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the SFI1 family.Curated

Phylogenomic databases

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
O13652

Identification of Orthologs from Complete Genome Data

More...
OMAi
AMKSHYS

Database for complete collections of gene phylogenies

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PhylomeDBi
O13652

Family and domain databases

Integrated resource of protein families, domains and functional sites

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InterProi
View protein in InterPro
IPR013665 Sfi1_dom

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF08457 Sfi1, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

O13652-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MSKNGAPKYV DGGRKIMDED LRRDLEILRL ILLRLSHAAD DTSPLDVFNA
60 70 80 90 100
YESVLRENGL NPARHRSYIR ILYRLISSKK LSWNDEWRNL MRRIGFSQVS
110 120 130 140 150
SDLNTPLFPL NNTDMENDPF IVNGDDYRSR SNQQKSSQFA SEVAQTIKSQ
160 170 180 190 200
TAMFRRADQY RSQKDKILLA NSLDFMLEKY RYYKKIDAVY LRKADAVYRA
210 220 230 240 250
FIMLKYFPRW VQKLRNIQSR IYSAGEAYRL ILIGQMVNRW RQKTRERLHQ
260 270 280 290 300
KLRFQKNAFL LDVLLKWSAL TVNWNRKHEY MLKRRVFTNW MSKRRRNESL
310 320 330 340 350
IQKANVFFQH SVLAHSFKTW KANLSIKNAA TLYEKKVVFM SFNRWHANYE
360 370 380 390 400
SHVLDLQKAE LFSQKAYYSI ALHKWKLRIE ELSDLMNKAD DLYEVNLLQR
410 420 430 440 450
MLVLWRRKAT TYEKIDFWMD GHDVDIVKSA FFKWKNKFIK VDRNFELADT
460 470 480 490 500
ILQNTFLTKW RLAVRVKVVQ EKRNKDRLIV TFRFWYYLMK AKSFQHKRDH
510 520 530 540 550
RLLTIAWEAW KDNYQRRIKL QKEAQELQLT RIQKIAKQYL IKWRISLLDI
560 570 580 590 600
KELSIRAEKL HTTNEIIGVW NQWVVSYNRK VGMQQNADLF FKRKTLRVVF
610 620 630 640 650
EHWRYLRETN MLLRLENKVV DFREVQSEKL VLRCWNAWVA RLLSVSQMLD
660 670 680 690 700
TAELSTQKVV VRAYEAWSFR YNHQKEIMSQ ADQFYNERLM RSAMVFWRYQ
710 720 730 740 750
LRAIKFYFNI SDWKRREFNR QTLRNAFDAW HLLMFRVTSL VMQADRFHEQ
760 770 780 790 800
KKNKLLGKYF RKWLQRMQLN QEESSLLEAE ATIEGNRTSR YMHTFDTTLP
810 820 830 840
MQNDEFTDES VNFENRWKQE LKTPISRFSK FLRPIPPNTR
Length:840
Mass (Da):102,033
Last modified:May 1, 2000 - v3
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i287E62DCC709184B
GO

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

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GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
CU329671 Genomic DNA Translation: CAA17820.2
AB004538 Genomic DNA Translation: BAA21440.1

Protein sequence database of the Protein Information Resource

More...
PIRi
T40750

NCBI Reference Sequences

More...
RefSeqi
NP_595568.1, NM_001021463.2

Genome annotation databases

Ensembl fungal genome annotation project

More...
EnsemblFungii
SPBC8D2.05c.1; SPBC8D2.05c.1:pep; SPBC8D2.05c

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
2541242

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
spo:SPBC8D2.05c

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CU329671 Genomic DNA Translation: CAA17820.2
AB004538 Genomic DNA Translation: BAA21440.1
PIRiT40750
RefSeqiNP_595568.1, NM_001021463.2

3D structure databases

Database of comparative protein structure models

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ModBasei
Search...

SWISS-MODEL Interactive Workspace

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SWISS-MODEL-Workspacei
Submit a new modelling project...

Protein-protein interaction databases

BioGridi277756, 2 interactors
IntActiO13652, 3 interactors
MINTiO13652
STRINGi4896.SPBC8D2.05c.1

PTM databases

iPTMnetiO13652

Proteomic databases

PaxDbiO13652
PRIDEiO13652

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblFungiiSPBC8D2.05c.1; SPBC8D2.05c.1:pep; SPBC8D2.05c
GeneIDi2541242
KEGGispo:SPBC8D2.05c

Organism-specific databases

EuPathDBiFungiDB:SPBC8D2.05c
PomBaseiSPBC8D2.05c sfi1

Phylogenomic databases

InParanoidiO13652
OMAiAMKSHYS
PhylomeDBiO13652

Miscellaneous databases

Protein Ontology

More...
PROi
PR:O13652

Family and domain databases

InterProiView protein in InterPro
IPR013665 Sfi1_dom
PfamiView protein in Pfam
PF08457 Sfi1, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiSFI1_SCHPO
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: O13652
Secondary accession number(s): Q7LWD9
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: June 12, 2007
Last sequence update: May 1, 2000
Last modified: July 31, 2019
This is version 97 of the entry and version 3 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
  2. Schizosaccharomyces pombe
    Schizosaccharomyces pombe: entries and gene names
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