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UniProtKB - O13395 (CHS6_USTMA)

Entry version 128 (23 Feb 2022)
Sequence version 2 (09 Jan 2007)
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Protein

Chitin synthase 6

Gene

CHS6

Organism
Ustilago maydis (strain 521 / FGSC 9021) (Corn smut fungus)
Status
Reviewed-Annotation score:

Annotation score:4 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>-Protein inferred from homologyi <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Polymerizes chitin, a structural polymer of the cell wall and septum, by transferring the sugar moiety of UDP-GlcNAc to the non-reducing end of the growing chitin polymer.

1 Publication

<p>This subsection of the <a href="http://www.uniprot.org/help/function%5Fsection">Function</a> section describes the catalytic activity of an enzyme, i.e. a chemical reaction that the enzyme catalyzes.<p><a href='/help/catalytic_activity' target='_top'>More...</a></p>Catalytic activityi

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

  • chitin synthase activity Source: GO_Central
Complete GO annotation on QuickGO ...

GO - Biological processi

Complete GO annotation on QuickGO ...

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionGlycosyltransferase, Transferase
Biological processCell wall biogenesis/degradation

Enzyme and pathway databases

BRENDA Comprehensive Enzyme Information System

More...BRENDAi		2.4.1.16, 6587

Protein family/group databases

Carbohydrate-Active enZymes

More...CAZyi		GT2, Glycosyltransferase Family 2

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Chitin synthase 6 (EC:2.4.1.16)
Alternative name(s):
Chitin-UDP acetyl-glucosaminyl transferase 6
Class-V chitin synthase 6
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:CHS6
ORF Names:UMAG_10367
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiUstilago maydis (strain 521 / FGSC 9021) (Corn smut fungus)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri237631 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryota › Fungi › Dikarya › Basidiomycota › Ustilaginomycotina › Ustilaginomycetes › Ustilaginales › Ustilaginaceae › Ustilago ›
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000000561 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 7

Organism-specific databases

Eukaryotic Pathogen, Vector and Host Database Resources

More...VEuPathDBi		FungiDB:UMAG_10367

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/subcellular%5Flocation%5Fsection">'Subcellular location'</a> section describes the extent of a membrane-spanning region of the protein. It denotes the presence of both alpha-helical transmembrane regions and the membrane spanning regions of beta-barrel transmembrane proteins.<p><a href='/help/transmem' target='_top'>More...</a></p>Transmembranei108 – 128HelicalSequence analysisAdd BLAST21
Transmembranei374 – 394HelicalSequence analysisAdd BLAST21
Transmembranei762 – 782HelicalSequence analysisAdd BLAST21
Transmembranei795 – 815HelicalSequence analysisAdd BLAST21
Transmembranei822 – 842HelicalSequence analysisAdd BLAST21

Keywords - Cellular componenti

Cell membrane, Cytoplasmic vesicle, Membrane

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Miscellaneous databases

Pathogen-Host Interaction database

More...PHI-basei		PHI:1116
PHI:389

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00001937241 – 1180Chitin synthase 6Add BLAST1180

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/ptm%5Fprocessing%5Fsection">PTM / Processing</a> section specifies the position and type of each covalently attached glycan group (mono-, di-, or polysaccharide).<p><a href='/help/carbohyd' target='_top'>More...</a></p>Glycosylationi737N-linked (GlcNAc...) asparagineSequence analysis1

Keywords - PTMi

Glycoprotein

Proteomic databases

PRoteomics IDEntifications database

More...PRIDEi		O13395

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

STRING: functional protein association networks

More...STRINGi		5270.UM03052P0

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family%5Fand%5Fdomains%5Fsection">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini1119 – 1174DEK C-terminalSequence analysisAdd BLAST56

<p>This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the chitin synthase family. Class V subfamily.Curated

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...eggNOGi		KOG2571, Eukaryota

InParanoid: Eukaryotic Ortholog Groups

More...InParanoidi		O13395

Database of Orthologous Groups

More...OrthoDBi		134286at2759

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

More...Gene3Di		3.10.120.10, 2 hits

Integrated resource of protein families, domains and functional sites

More...InterProi		View protein in InterPro
IPR004835, Chitin_synth
IPR001199, Cyt_B5-like_heme/steroid-bd
IPR036400, Cyt_B5-like_heme/steroid_sf
IPR014876, DEK_C
IPR029044, Nucleotide-diphossugar_trans

The PANTHER Classification System

More...PANTHERi		PTHR22914, PTHR22914, 1 hit

Pfam protein domain database

More...Pfami		View protein in Pfam
PF00173, Cyt-b5, 2 hits
PF08766, DEK_C, 1 hit

Simple Modular Architecture Research Tool; a protein domain database

More...SMARTi		View protein in SMART
SM01117, Cyt-b5, 2 hits

Superfamily database of structural and functional annotation

More...SUPFAMi		SSF53448, SSF53448, 1 hit
SSF55856, SSF55856, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

O13395-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MSTKDAHDPF ATPLETITHD PLAETAGLKA DYDKRAYGEA NPALMGTLEK 
        60         70         80         90        100
DDMANRPIDA VEEVPTTSIR KWWVRLTWFT TWWIPSFVLS KCGGMKRPDV 
       110        120        130        140        150
QMAWREKFTI CAIIFWLCAI ILFYIIAFGR LLCPDYDKAW NLSQLSQHAG 
       160        170        180        190        200
ENDYYAAVRG TVYDFSKFYK GDHSDITNLQ TSSDLMLQLA GQDLTGYFPV 
       210        220        230        240        250
PLSVGCQSLV SDTSLALMPT ANNTPLISQA IHTSGPLQGD TSSKLHDINW 
       260        270        280        290        300
YPDRFLPFVK KLRKGYYVYS KKDLANQGQW RNWAVIHGKV YDLSNYLNTV 
       310        320        330        340        350
STYQTNPAYS FLDSSIVSLF KSQAGSDITA DFEDAMSTFN QTYRGATQAC 
       360        370        380        390        400
LDNVFYVGRT DFRDTARCEV QNYLLLAFSV LLVTTVLAKF IAALQLGTKR 
       410        420        430        440        450
SPEQQDKFVI CQVPCYTEGE EELRKTIDSL AGLEYDDKRK LLFLICDGMI 
       460        470        480        490        500
VGSGNDRSTP RIVLDILGVD PKIDPEPLMF KSVAEGSKQL NYAKVYSGLY 
       510        520        530        540        550
EFEGHVVPYI VVVKVGRPSE RSRPGNRGKR DSQILLMRYL NRVHFDAPMF 
       560        570        580        590        600
PLELEIYHQM KNVIGIDPAF YEYILMVDAD TRVEADGLNR LVANCADDSS 
       610        620        630        640        650
IIAICGETTL DNAEGSWWTM IQVYEYYISH HLSKAFESLF GSVTCLPGCF 
       660        670        680        690        700
SLYRIRSSDK GRPLFISNRI IDDYSENRVD TLHKKNLLHL GEDRYLTTLV 
       710        720        730        740        750
LKNFPSFRTK FVPDAKALTS APDRFGVLLS QRRRWINSTV HNLAELVLMP 
       760        770        780        790        800
ELCGFCLFSM RFIVFIDLLG TVILPATAVY LVYLIVTVAT KSAPIPYISI 
       810        820        830        840        850
AMIAAVYGLQ AILFLLKRQW QYIGWLVIYI LAYPVFSFFL PIYSFWHMDD 
       860        870        880        890        900
FSWGNTRIVV GEKGNKKIVA GTDDEPYDDT MIPLKRFSEY QREVWEEEAA 
       910        920        930        940        950
APSMRSGMTG ASGPFGNSQA ILHSGPPSVY RAGGSAYAGS VAGSDYGAGL 
       960        970        980        990       1000
GDYYQNTNVL QKPAHSRQTS AAALSQMGGS QAASMMFGTG TPSVYGMAGM 
      1010       1020       1030       1040       1050
GSMYGMPGSS ASMYGLPNPM MNTTASMYGL PPMLANPLGA NHSPAHSDIG 
      1060       1070       1080       1090       1100
VSMPVSQQNT GGSHIWAQPP EAATVAANSG RGSGMQARPV STLSALNATN 
      1110       1120       1130       1140       1150
PFGVTAVARA LAVNEASDPT DEEIKSAVQT YLANQPSLMN VTKRSVREAL 
      1160       1170       1180
VAAFPNAELS YKKSMINKAI DDTLSGGAQA
Length:1,180
Mass (Da):130,623
Last modified:January 9, 2007 - v2
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i72974D483D5F684B
GO

<p>This subsection of the 'Sequence' section reports difference(s) between the protein sequence shown in the UniProtKB entry and other available protein sequences derived from the same gene.<p><a href='/help/sequence_caution' target='_top'>More...</a></p>Sequence cautioni

The sequence AAB84285 differs from that shown. Reason: Frameshift.Curated

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti196G → R in AAB84285 (PubMed:9454647).Curated1

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...EMBLi

GenBank nucleotide sequence database

More...GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...DDBJi
Links Updated
AF030554 Genomic DNA Translation: AAB84285.1 Frameshift.
CM003146 Genomic DNA Translation: KIS69073.1

Protein sequence database of the Protein Information Resource

More...PIRi		T42022

NCBI Reference Sequences

More...RefSeqi		XP_011389509.1, XM_011391207.1

Genome annotation databases

Ensembl fungal genome annotation project

More...EnsemblFungii		KIS69073; KIS69073; UMAG_10367

Database of genes from NCBI RefSeq genomes

More...GeneIDi		23566410

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...KEGGi		uma:UMAG_10367

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF030554 Genomic DNA Translation: AAB84285.1 Frameshift.
CM003146 Genomic DNA Translation: KIS69073.1
PIRiT42022
RefSeqiXP_011389509.1, XM_011391207.1

3D structure databases

Database of comparative protein structure models

More...ModBasei		Search...

SWISS-MODEL Interactive Workspace

More...SWISS-MODEL-Workspacei		Submit a new modelling project...

Protein-protein interaction databases

STRINGi5270.UM03052P0

Protein family/group databases

CAZyiGT2, Glycosyltransferase Family 2

Proteomic databases

PRIDEiO13395

Genome annotation databases

EnsemblFungiiKIS69073; KIS69073; UMAG_10367
GeneIDi23566410
KEGGiuma:UMAG_10367

Organism-specific databases

VEuPathDBiFungiDB:UMAG_10367

Phylogenomic databases

eggNOGiKOG2571, Eukaryota
InParanoidiO13395
OrthoDBi134286at2759

Enzyme and pathway databases

BRENDAi2.4.1.16, 6587

Miscellaneous databases

PHI-baseiPHI:1116
PHI:389

Family and domain databases

Gene3Di3.10.120.10, 2 hits
InterProiView protein in InterPro
IPR004835, Chitin_synth
IPR001199, Cyt_B5-like_heme/steroid-bd
IPR036400, Cyt_B5-like_heme/steroid_sf
IPR014876, DEK_C
IPR029044, Nucleotide-diphossugar_trans
PANTHERiPTHR22914, PTHR22914, 1 hit
PfamiView protein in Pfam
PF00173, Cyt-b5, 2 hits
PF08766, DEK_C, 1 hit
SMARTiView protein in SMART
SM01117, Cyt-b5, 2 hits
SUPFAMiSSF53448, SSF53448, 1 hit
SSF55856, SSF55856, 1 hit

MobiDB: a database of protein disorder and mobility annotations

More...MobiDBi		Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiCHS6_USTMA
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: O13395
Secondary accession number(s): A0A0D1CR95, Q4PA11
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: July 15, 1999
Last sequence update: January 9, 2007
Last modified: February 23, 2022
This is version 128 of the entry and version 2 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
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