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UniProtKB - O13353 (CHS4_MAGO7)

Entry version 122 (23 Feb 2022)
Sequence version 2 (12 Jun 2007)
Previous versions | rss
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Protein

Chitin synthase 4

Gene

CHS4

Organism
Magnaporthe oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958) (Rice blast fungus) (Pyricularia oryzae)
Status
Reviewed-Annotation score:

Annotation score:4 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>-Protein inferred from homologyi <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Polymerizes chitin, a structural polymer of the cell wall and septum, by transferring the sugar moiety of UDP-GlcNAc to the non-reducing end of the growing chitin polymer.

Curated

<p>This subsection of the <a href="http://www.uniprot.org/help/function%5Fsection">Function</a> section describes the catalytic activity of an enzyme, i.e. a chemical reaction that the enzyme catalyzes.<p><a href='/help/catalytic_activity' target='_top'>More...</a></p>Catalytic activityi

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

Complete GO annotation on QuickGO ...

GO - Biological processi

Complete GO annotation on QuickGO ...

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionGlycosyltransferase, Transferase
Biological processCell wall biogenesis/degradation

Protein family/group databases

Carbohydrate-Active enZymes

More...CAZyi		GT2, Glycosyltransferase Family 2

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Chitin synthase 4 (EC:2.4.1.16)
Alternative name(s):
Chitin-UDP acetyl-glucosaminyl transferase 4
Class-IV chitin synthase 4
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:CHS4
ORF Names:MGG_09962
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiMagnaporthe oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958) (Rice blast fungus) (Pyricularia oryzae)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri242507 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryota › Fungi › Dikarya › Ascomycota › Pezizomycotina › Sordariomycetes › Sordariomycetidae › Magnaporthales › Pyriculariaceae › Pyricularia ›
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000009058 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 1

Organism-specific databases

Eukaryotic Pathogen, Vector and Host Database Resources

More...VEuPathDBi		FungiDB:MGG_09962

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/subcellular%5Flocation%5Fsection">'Subcellular location'</a> section describes the subcellular compartment where each non-membrane region of a membrane-spanning protein is found.<p><a href='/help/topo_dom' target='_top'>More...</a></p>Topological domaini1 – 202CytoplasmicCuratedAdd BLAST202
<p>This subsection of the <a href="http://www.uniprot.org/help/subcellular%5Flocation%5Fsection">'Subcellular location'</a> section describes the extent of a membrane-spanning region of the protein. It denotes the presence of both alpha-helical transmembrane regions and the membrane spanning regions of beta-barrel transmembrane proteins.<p><a href='/help/transmem' target='_top'>More...</a></p>Transmembranei203 – 223HelicalSequence analysisAdd BLAST21
Topological domaini224 – 240ExtracellularCuratedAdd BLAST17
Transmembranei241 – 261HelicalSequence analysisAdd BLAST21
Topological domaini262 – 495CytoplasmicCuratedAdd BLAST234
Transmembranei496 – 516HelicalSequence analysisAdd BLAST21
Topological domaini517 – 1054ExtracellularCuratedAdd BLAST538
Transmembranei1055 – 1075HelicalSequence analysisAdd BLAST21
Topological domaini1076 – 1088CytoplasmicCuratedAdd BLAST13
Transmembranei1089 – 1109HelicalSequence analysisAdd BLAST21
Topological domaini1110 – 1114ExtracellularCurated5
Transmembranei1115 – 1135HelicalSequence analysisAdd BLAST21
Topological domaini1136 – 1229CytoplasmicCuratedAdd BLAST94

Keywords - Cellular componenti

Cell membrane, Membrane

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00001937001 – 1229Chitin synthase 4Add BLAST1229

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/ptm%5Fprocessing%5Fsection">PTM / Processing</a> section specifies the position and type of each covalently attached glycan group (mono-, di-, or polysaccharide).<p><a href='/help/carbohyd' target='_top'>More...</a></p>Glycosylationi608N-linked (GlcNAc...) asparaginePROSITE-ProRule annotation1
Glycosylationi635N-linked (GlcNAc...) asparaginePROSITE-ProRule annotation1
Glycosylationi1030N-linked (GlcNAc...) asparaginePROSITE-ProRule annotation1

Keywords - PTMi

Glycoprotein

Proteomic databases

PRoteomics IDEntifications database

More...PRIDEi		O13353

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

STRING: functional protein association networks

More...STRINGi		318829.MGG_09962T0

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni1 – 196DisorderedSequence analysisAdd BLAST196
Regioni539 – 589DisorderedSequence analysisAdd BLAST51
Regioni601 – 648DisorderedSequence analysisAdd BLAST48
Regioni1210 – 1229DisorderedSequence analysisAdd BLAST20

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes the position of regions of compositional bias within the protein and the particular type of amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi45 – 80Polar residuesSequence analysisAdd BLAST36
Compositional biasi81 – 109Basic and acidic residuesSequence analysisAdd BLAST29
Compositional biasi136 – 151Polar residuesSequence analysisAdd BLAST16
Compositional biasi154 – 196Basic and acidic residuesSequence analysisAdd BLAST43
Compositional biasi539 – 560Basic and acidic residuesSequence analysisAdd BLAST22
Compositional biasi573 – 589Polar residuesSequence analysisAdd BLAST17
Compositional biasi601 – 647Polar residuesSequence analysisAdd BLAST47

<p>This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the chitin synthase family. Class IV subfamily.Curated

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...eggNOGi		KOG2571, Eukaryota

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...HOGENOMi		CLU_002572_1_0_1

InParanoid: Eukaryotic Ortholog Groups

More...InParanoidi		O13353

Identification of Orthologs from Complete Genome Data

More...OMAi		FPLAHTM

Database of Orthologous Groups

More...OrthoDBi		134286at2759

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

More...Gene3Di		3.90.550.10, 1 hit

Integrated resource of protein families, domains and functional sites

More...InterProi		View protein in InterPro
IPR004835, Chitin_synth
IPR001199, Cyt_B5-like_heme/steroid-bd
IPR029044, Nucleotide-diphossugar_trans

The PANTHER Classification System

More...PANTHERi		PTHR22914, PTHR22914, 1 hit

Simple Modular Architecture Research Tool; a protein domain database

More...SMARTi		View protein in SMART
SM01117, Cyt-b5, 1 hit

Superfamily database of structural and functional annotation

More...SUPFAMi		SSF53448, SSF53448, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

O13353-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MSLPERPGAK ASYEQRNSYR KSPSRRNRPN DIEASGYYPV TGGQHQRGPS 
        60         70         80         90        100
VNSFAETIRS PNSNIESAPL SPSAEQIEHG SDQPFQRKRS LIRPERNRID 
       110        120        130        140        150
RDHPNYHYRK HAAKMNTLPS STGNDPVLED VSGATESGPP SGSNSASGSG 
       160        170        180        190        200
VREENIPRKS RKASGRETVA EKSDNTRRRV STRNSKIVKE GKRKEKIPEQ 
       210        220        230        240        250
LRPPSAWNVY CAVITFWSPD FIMKCCGMPA KAQRRAWREK IGLISLILII 
       260        270        280        290        300
MGVVGFLTFG FNQAVCGGPV LRLHINSVDR SYMIFHGTAY NLDGSHHPVA 
       310        320        330        340        350
EGIPKRLDGT GANVVYDLPE GYGGTDGSFM FQNVNGKCKG LITKAPNSDV 
       360        370        380        390        400
PSEGDNLAWY FPCHARNQDG SSQPNMTYPY YFGYACHTTP LARSTFYTQL 
       410        420        430        440        450
DKSADVYFTW ADIRNNSRNL FVYSGNVLDL DLLFWFNRDQ VNIPRRFEEL 
       460        470        480        490        500
RDKNNAANRA IRGRDATRTF MASGDRQIAE CFEDIIKVGT VDTDTVGCIA 
       510        520        530        540        550
AKVVLYVSLA LILSVVGARF TLALIFQWFI SKNYAADKTS QTSDKRKRNK 
       560        570        580        590        600
QIEDWSEDIY RAPPRMPGDV GSSVAGASSS DHTSKRSSFL PTTSRFSTVY 
       610        620        630        640        650
GAERSARNKS MPTTMASQAS GGYMGPSSTA YRETNESRTS FLKSDPYATN 
       660        670        680        690        700
TAPIEGPGPS GFIHDSVVPQ PPSDWMPFGF PLAHTICLVT AYSEGELGLR 
       710        720        730        740        750
TTLDSVAMTD YPNSHKVILV ICDGIIKGKG ESKSTPEYVL DMMKDHTIPV 
       760        770        780        790        800
EDVEAFSYVA VASGSKRHNM AKIYAGFYDY GTQSNIPLDK QQRVPMMVVV 
       810        820        830        840        850
KCGTPDEMVK SKPGNRGKRD SQIILMSFLQ KVMFDERMTE LEYEMFNGLW 
       860        870        880        890        900
KVTGISPDFY EIVLMVDADT KVFPDSLTHM ISAMVKDPEI MGLCGETKIA 
       910        920        930        940        950
NKRDSWVSAI QVFEYFISHH LAKSFESVFG GVTCLPGCFC MYRIKAPKGA 
       960        970        980        990       1000
QNYWVPILAN PDVVEHYSEN VVDTLHKKNL LLLGEDRYLT TLMLRTFPKR 
      1010       1020       1030       1040       1050
KQVFVPQAVC KTTVPDSFMV LLSQRRRWIN STIHNLMELV LVRDLCGTFC 
      1060       1070       1080       1090       1100
FSMQFVIFIE LIGTLVLPAA IAFTFYVVII SIINQPPQII PLVLLGLILG 
      1110       1120       1130       1140       1150
LPAILIIITA HSWSYVLWML IYLLSLPVWN FVLPAYAFWK FDDFSWGDTR 
      1160       1170       1180       1190       1200
KTAGEKTKKA GIEYEGEFDS SKITMKRWAE FERDRRARQS QYWGSRENVT 
      1210       1220 
GGVRTASGVW ASAPPHHHQQ QYDEYYSDA
Length:1,229
Mass (Da):137,828
Last modified:June 12, 2007 - v2
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i388030A667144D55
GO

<p>This subsection of the 'Sequence' section reports difference(s) between the protein sequence shown in the UniProtKB entry and other available protein sequences derived from the same gene.<p><a href='/help/sequence_caution' target='_top'>More...</a></p>Sequence cautioni

The sequence AAB71411 differs from that shown. Reason: Frameshift.Curated

Natural variant

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section describes natural variant(s) of the protein sequence.<p><a href='/help/variant' target='_top'>More...</a></p>Natural varianti545 – 546KR → NG in strain: Guyane 11. 2

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...EMBLi

GenBank nucleotide sequence database

More...GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...DDBJi
Links Updated
AF020528 Genomic DNA Translation: AAB71411.1 Frameshift.
CM001231 Genomic DNA Translation: EHA57460.1
CM001231 Genomic DNA Translation: EHA57461.1

NCBI Reference Sequences

More...RefSeqi		XP_003710072.1, XM_003710024.1
XP_003710073.1, XM_003710025.1

Genome annotation databases

Ensembl fungal genome annotation project

More...EnsemblFungii		MGG_09962T0; MGG_09962T0; MGG_09962
MGG_09962T1; MGG_09962T1; MGG_09962

Database of genes from NCBI RefSeq genomes

More...GeneIDi		2680870

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...KEGGi		mgr:MGG_09962

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF020528 Genomic DNA Translation: AAB71411.1 Frameshift.
CM001231 Genomic DNA Translation: EHA57460.1
CM001231 Genomic DNA Translation: EHA57461.1
RefSeqiXP_003710072.1, XM_003710024.1
XP_003710073.1, XM_003710025.1

3D structure databases

Database of comparative protein structure models

More...ModBasei		Search...

SWISS-MODEL Interactive Workspace

More...SWISS-MODEL-Workspacei		Submit a new modelling project...

Protein-protein interaction databases

STRINGi318829.MGG_09962T0

Protein family/group databases

CAZyiGT2, Glycosyltransferase Family 2

Proteomic databases

PRIDEiO13353

Genome annotation databases

EnsemblFungiiMGG_09962T0; MGG_09962T0; MGG_09962
MGG_09962T1; MGG_09962T1; MGG_09962
GeneIDi2680870
KEGGimgr:MGG_09962

Organism-specific databases

VEuPathDBiFungiDB:MGG_09962

Phylogenomic databases

eggNOGiKOG2571, Eukaryota
HOGENOMiCLU_002572_1_0_1
InParanoidiO13353
OMAiFPLAHTM
OrthoDBi134286at2759

Family and domain databases

Gene3Di3.90.550.10, 1 hit
InterProiView protein in InterPro
IPR004835, Chitin_synth
IPR001199, Cyt_B5-like_heme/steroid-bd
IPR029044, Nucleotide-diphossugar_trans
PANTHERiPTHR22914, PTHR22914, 1 hit
SMARTiView protein in SMART
SM01117, Cyt-b5, 1 hit
SUPFAMiSSF53448, SSF53448, 1 hit

MobiDB: a database of protein disorder and mobility annotations

More...MobiDBi		Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiCHS4_MAGO7
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: O13353
Secondary accession number(s): A4R0F5, G4MRN7
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: July 15, 1999
Last sequence update: June 12, 2007
Last modified: February 23, 2022
This is version 122 of the entry and version 2 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
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