pmt3

Functionⁱ

Required for chromosome segregation where it may be involved in microtubule assembly. Loss of smt3 leads to an increase in telomere length.1 Publication

GO - Molecular functionⁱ

protein tag
Source: PomBase
Inferred from direct assayⁱ
- 28552615

View the complete GO annotation on QuickGO ...

GO - Biological processⁱ

chromatin silencing at centromere
Source: PomBase
Inferred from mutant phenotypeⁱ
- 16168376
chromatin silencing at silent mating-type cassette
Source: PomBase
Inferred from mutant phenotypeⁱ
- 16168376
negative regulation of histone H3-K14 acetylation
Source: PomBase
Inferred from mutant phenotypeⁱ
- 16168376
negative regulation of histone H3-K4 methylation
Source: PomBase
Inferred from mutant phenotypeⁱ
- 16168376
negative regulation of histone H3-K9 methylation
Source: PomBase
Inferred from mutant phenotypeⁱ
- 16168376
protein sumoylation
Source: PomBase
Inferred from direct assayⁱ
- 28552615
telomere maintenance
Source: PomBase
Inferred from mutant phenotypeⁱ
- 10567589

View the complete GO annotation on QuickGO ...

Keywordsⁱ

Biological process	Ubl conjugation pathway

Biological process

Ubl conjugation pathway

Enzyme and pathway databases

Reactomeⁱ	R-SPO-3065676 SUMO is conjugated to E1 (UBA2:SAE1) R-SPO-3065678 SUMO is transferred from E1 to E2 (UBE2I, UBC9) R-SPO-3065679 SUMO is proteolytically processed R-SPO-3108214 SUMOylation of DNA damage response and repair proteins R-SPO-3899300 SUMOylation of transcription cofactors R-SPO-4085377 SUMOylation of SUMOylation proteins R-SPO-4551638 SUMOylation of chromatin organization proteins R-SPO-4570464 SUMOylation of RNA binding proteins R-SPO-4615885 SUMOylation of DNA replication proteins

Reactomeⁱ

R-SPO-3065676 SUMO is conjugated to E1 (UBA2:SAE1)
R-SPO-3065678 SUMO is transferred from E1 to E2 (UBE2I, UBC9)
R-SPO-3065679 SUMO is proteolytically processed
R-SPO-3108214 SUMOylation of DNA damage response and repair proteins
R-SPO-3899300 SUMOylation of transcription cofactors
R-SPO-4085377 SUMOylation of SUMOylation proteins
R-SPO-4551638 SUMOylation of chromatin organization proteins
R-SPO-4570464 SUMOylation of RNA binding proteins
R-SPO-4615885 SUMOylation of DNA replication proteins

Names & Taxonomyⁱ

Protein namesⁱ	Recommended name: Ubiquitin-like protein pmt3/smt3
Gene namesⁱ	Name:pmt3 Synonyms:smt3, ubl2 ORF Names:SPBC365.06
Organismⁱ	Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Taxonomic identifierⁱ	284812 [NCBI]
Taxonomic lineageⁱ	cellular organisms › Eukaryota › Opisthokonta › Fungi › Dikarya › Ascomycota › Taphrinomycotina › Schizosaccharomycetes › Schizosaccharomycetales › Schizosaccharomycetaceae › Schizosaccharomyces › Schizosaccharomyces pombe
Proteomesⁱ	UP000002485 Componentⁱ: Chromosome II

Organism-specific databases

EuPathDBⁱ	FungiDB:SPBC365.06
PomBaseⁱ	SPBC365.06 pmt3

Keywords - Cellular componentⁱ

Nucleus

PTM / Processingⁱ

Molecule processing

Feature key	Position(s)	DescriptionActions	Graphical view	Length
ChainⁱPRO_0000035961	1 – 111	Ubiquitin-like protein pmt3/smt3Add BLAST		111
PropeptideⁱPRO_0000035962	112 – 117	Sequence analysis		6

Amino acid modifications

Feature key	Position(s)	DescriptionActions	Graphical view	Length
Cross-linkⁱ	111	Glycyl lysine isopeptide (Gly-Lys) (interchain with K-? in acceptor proteins)

Keywords - PTMⁱ

Isopeptide bond

Proteomic databases

MaxQB - The MaxQuant DataBase More...MaxQBⁱ	O13351
PaxDbⁱ	O13351
PRIDEⁱ	O13351

PTM databases

iPTMnetⁱ	O13351

iPTMnetⁱ

O13351

Interactionⁱ

Subunit structureⁱ

Interacts with rfp1.1 Publication

Binary interactionsⁱ

With	Entry	#Exp.	IntAct	Notes
rad22	P36592	4	EBI-966336,EBI-966242
rfp1	O13826	5	EBI-966336,EBI-3647269

Protein-protein interaction databases

BioGridⁱ	277443, 54 interactors
IntActⁱ	O13351, 10 interactors
Molecular INTeraction database More...MINTⁱ	O13351
STRINGⁱ	4896.SPBC365.06.1

Structureⁱ

3D structure databases

ProteinModelPortalⁱ	O13351
SMRⁱ	O13351
ModBaseⁱ	Search...
MobiDBⁱ	Search...

Family & Domainsⁱ

Domains and Repeats

Feature key	Position(s)	DescriptionActions	Graphical view	Length
Domainⁱ	35 – 115	Ubiquitin-likePROSITE-ProRule annotationAdd BLAST		81

Sequence similaritiesⁱ

Belongs to the ubiquitin family. SUMO subfamily.Curated

Phylogenomic databases

HOGENOMⁱ	HOG000207495
InParanoidⁱ	O13351
KEGG Orthology (KO) More...KOⁱ	K12160
OMAⁱ	NDTIDVM
Database of Orthologous Groups More...OrthoDBⁱ	EOG092C5C59
PhylomeDBⁱ	O13351

Family and domain databases

Conserved Domains Database More...CDDⁱ	cd01763 Sumo, 1 hit
InterProⁱ	View protein in InterPro IPR022617 Rad60/SUMO-like_dom IPR033950 Sumo IPR029071 Ubiquitin-like_domsf IPR000626 Ubiquitin_dom
Pfam protein domain database More...Pfamⁱ	View protein in Pfam PF11976 Rad60-SLD, 1 hit
SMARTⁱ	View protein in SMART SM00213 UBQ, 1 hit
SUPFAMⁱ	SSF54236 SSF54236, 1 hit
PROSITEⁱ	View protein in PROSITE PS50053 UBIQUITIN_2, 1 hit

Sequenceⁱ

Sequence statusⁱ: Complete.

Sequence processingⁱ: The displayed sequence is further processed into a mature form.

O13351-1 [UniParc]FASTA Add to basket

« Hide

        10         20         30         40         50
MSESPSANIS DADKSAITPT TGDTSQQDVK PSTEHINLKV VGQDNNEVFF 
        60         70         80         90        100
KIKKTTEFSK LMKIYCARQG KSMNSLRFLV DGERIRPDQT PAELDMEDGD 
       110 
QIEAVLEQLG GCTHLCL

Length:117

Mass (Da):12,935

Last modified:January 11, 2001 - v2

Checksum:ⁱ11C860EBEA172FD2

GO

Sequence cautionⁱ

The sequence AAB71541 differs from that shown. Reason: Frameshift at position 29.Curated

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	AB017187 Genomic DNA Translation: BAA32595.1 CU329671 Genomic DNA Translation: CAB44758.1 AF019235 mRNA Translation: AAB71541.1 Frameshift.
PIRⁱ	T40313 T43537
NCBI Reference Sequences More...RefSeqⁱ	NP_596035.1, NM_001021945.2

Genome annotation databases

EnsemblFungiⁱ	SPBC365.06.1; SPBC365.06.1:pep; SPBC365.06
KEGGⁱ	spo:SPBC365.06

Similar proteinsⁱ

50% Identity

Protein	Similar proteins		Species	Score	Length	Source
O13351	Ubiquitin-like protein pmt3/smt3 (Fragment)		Anthurium amnicola		144	UniRef50_O13351
Uncharacterized protein		SCHJY		117

Cross-referencesⁱ

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	AB017187 Genomic DNA Translation: BAA32595.1 CU329671 Genomic DNA Translation: CAB44758.1 AF019235 mRNA Translation: AAB71541.1 Frameshift.
PIRⁱ	T40313 T43537
RefSeqⁱ	NP_596035.1, NM_001021945.2

3D structure databases

ProteinModelPortalⁱ	O13351
SMRⁱ	O13351
ModBaseⁱ	Search...
MobiDBⁱ	Search...

Protein-protein interaction databases

BioGridⁱ	277443, 54 interactors
IntActⁱ	O13351, 10 interactors
MINTⁱ	O13351
STRINGⁱ	4896.SPBC365.06.1

PTM databases

iPTMnetⁱ	O13351

iPTMnetⁱ

O13351

Proteomic databases

MaxQBⁱ	O13351
PaxDbⁱ	O13351
PRIDEⁱ	O13351

Protocols and materials databases

Structural Biology Knowledgebase	Search...

Structural Biology Knowledgebase

Search...

Genome annotation databases

EnsemblFungiⁱ	SPBC365.06.1; SPBC365.06.1:pep; SPBC365.06
KEGGⁱ	spo:SPBC365.06

Organism-specific databases

EuPathDBⁱ	FungiDB:SPBC365.06
PomBaseⁱ	SPBC365.06 pmt3

Phylogenomic databases

HOGENOMⁱ	HOG000207495
InParanoidⁱ	O13351
KOⁱ	K12160
OMAⁱ	NDTIDVM
OrthoDBⁱ	EOG092C5C59
PhylomeDBⁱ	O13351

Enzyme and pathway databases

Reactomeⁱ	R-SPO-3065676 SUMO is conjugated to E1 (UBA2:SAE1) R-SPO-3065678 SUMO is transferred from E1 to E2 (UBE2I, UBC9) R-SPO-3065679 SUMO is proteolytically processed R-SPO-3108214 SUMOylation of DNA damage response and repair proteins R-SPO-3899300 SUMOylation of transcription cofactors R-SPO-4085377 SUMOylation of SUMOylation proteins R-SPO-4551638 SUMOylation of chromatin organization proteins R-SPO-4570464 SUMOylation of RNA binding proteins R-SPO-4615885 SUMOylation of DNA replication proteins

Reactomeⁱ

R-SPO-3065676 SUMO is conjugated to E1 (UBA2:SAE1)
R-SPO-3065678 SUMO is transferred from E1 to E2 (UBE2I, UBC9)
R-SPO-3065679 SUMO is proteolytically processed
R-SPO-3108214 SUMOylation of DNA damage response and repair proteins
R-SPO-3899300 SUMOylation of transcription cofactors
R-SPO-4085377 SUMOylation of SUMOylation proteins
R-SPO-4551638 SUMOylation of chromatin organization proteins
R-SPO-4570464 SUMOylation of RNA binding proteins
R-SPO-4615885 SUMOylation of DNA replication proteins

Miscellaneous databases

Protein Ontology More...PROⁱ	PR:O13351

PROⁱ

PR:O13351

Family and domain databases

CDDⁱ	cd01763 Sumo, 1 hit
InterProⁱ	View protein in InterPro IPR022617 Rad60/SUMO-like_dom IPR033950 Sumo IPR029071 Ubiquitin-like_domsf IPR000626 Ubiquitin_dom
Pfamⁱ	View protein in Pfam PF11976 Rad60-SLD, 1 hit
SMARTⁱ	View protein in SMART SM00213 UBQ, 1 hit
SUPFAMⁱ	SSF54236 SSF54236, 1 hit
PROSITEⁱ	View protein in PROSITE PS50053 UBIQUITIN_2, 1 hit
ProtoNetⁱ	Search...

Entry informationⁱ

Entry nameⁱ	PMT3_SCHPO
Accessionⁱ	O13351Primary (citable) accession number: O13351 Secondary accession number(s): O74186
Entry historyⁱ	Integrated into UniProtKB/Swiss-Prot:	July 15, 1998
	Last sequence update:	January 11, 2001
	Last modified:	September 12, 2018
	This is version 149 of the entry and version 2 of the sequence. See complete history.
Entry statusⁱ	Reviewed (UniProtKB/Swiss-Prot)
Annotation program	Fungal Protein Annotation Program

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UniParc

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UniRef

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Supporting data

UniProtKB - O13351 (PMT3_SCHPO)

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Ubiquitin-like protein pmt3/smt3

Select a section on the left to see content.

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

Enzyme and pathway databases

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

Organism-specific databases

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Nucleus

Cytoskeleton

Nucleus

Other locations

Keywords - Cellular componenti

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Amino acid modifications

Keywords - PTMi

Proteomic databases

PTM databases

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

<p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Phylogenomic databases

Family and domain databases

<p>This subsection of the ‘Sequence’ section reports difference(s) between the protein sequence shown in the UniProtKB entry and other available protein sequences derived from the same gene.<p><a href='/help/sequence_caution' target='_top'>More...</a></p>Sequence cautioni

Sequence databases

Genome annotation databases

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

3D structure databases

Protein-protein interaction databases

PTM databases

Proteomic databases

Protocols and materials databases

Genome annotation databases

Organism-specific databases

Phylogenomic databases

Enzyme and pathway databases

Miscellaneous databases

Family and domain databases

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

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Functionⁱ

GO - Molecular functionⁱ

GO - Biological processⁱ

Names & Taxonomyⁱ

Subcellular locationⁱ

Keywords - Cellular componentⁱ

PTM / Processingⁱ

Keywords - PTMⁱ

Interactionⁱ

Structureⁱ

Family & Domainsⁱ

Sequence similaritiesⁱ

Sequence cautionⁱ

Cross-referencesⁱ

Entry informationⁱ

Miscellaneousⁱ

Keywords - Technical termⁱ