Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Entry version 127 (08 May 2019)
Sequence version 2 (22 Nov 2017)
Previous versions | rss
Other tutorials and videosHelp videoFeedback
Protein

Transducin-like enhancer protein 3-B

Gene

tle3b

Organism
Danio rerio (Zebrafish) (Brachydanio rerio)
Status
Reviewed-Annotation score:

Annotation score:4 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Transcriptional corepressor that binds to a number of transcription factors.By similarity

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

Enzyme and pathway databases

Reactome - a knowledgebase of biological pathways and processes

More...
Reactomei
R-DRE-201722 Formation of the beta-catenin:TCF transactivating complex
R-DRE-3769402 Deactivation of the beta-catenin transactivating complex
R-DRE-4641265 Repression of WNT target genes
R-DRE-9018519 Estrogen-dependent gene expression

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Transducin-like enhancer protein 3-BCurated
Alternative name(s):
Protein groucho-11 Publication
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:tle3bCurated
Synonyms:gro11 Publication, groucho11 Publication
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiDanio rerio (Zebrafish) (Brachydanio rerio)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri7955 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiActinopterygiiNeopterygiiTeleosteiOstariophysiCypriniformesCyprinidaeDanio
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000000437 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 7

Organism-specific databases

Zebrafish Information Network genome database

More...
ZFINi
ZDB-GENE-990415-85 tle3b

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Cellular componenti

Nucleus

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00000512881 – 771Transducin-like enhancer protein 3-BAdd BLAST771

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section specifies the position and type of each modified residue excluding <a href="http://www.uniprot.org/manual/lipid">lipids</a>, <a href="http://www.uniprot.org/manual/carbohyd">glycans</a> and <a href="http://www.uniprot.org/manual/crosslnk">protein cross-links</a>.<p><a href='/help/mod_res' target='_top'>More...</a></p>Modified residuei296Phosphoserine1 Publication1
Modified residuei299Phosphoserine1 Publication1

Keywords - PTMi

Phosphoprotein

Proteomic databases

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
O13168

PRoteomics IDEntifications database

More...
PRIDEi
O13168

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
O13168

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

<p>This subsection of the ‘Expression’ section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms. By default, the information is derived from experiments at the mRNA level, unless specified ‘at protein level’. <br></br>Examples: <a href="http://www.uniprot.org/uniprot/P92958#expression">P92958</a>, <a href="http://www.uniprot.org/uniprot/Q8TDN4#expression">Q8TDN4</a>, <a href="http://www.uniprot.org/uniprot/O14734#expression">O14734</a><p><a href='/help/tissue_specificity' target='_top'>More...</a></p>Tissue specificityi

At gastrulation, expression is absent within the axial mesoderm. After gastrulation is complete, expressed in the presomitic mesoderm, but expression in the tailbud doesn't begin until the six to seven somite stage, after which it becomes abundant. Expression is abundant throughout somitogenesis within the posterior half of the somites, but is absent from older somites. Also expressed in a dynamic manner within the neural plate.1 Publication

<p>This subsection of the ‘Expression’ section provides information on the expression of the gene product at various stages of a cell, tissue or organism development. By default, the information is derived from experiments at the mRNA level, unless specified ‘at the protein level’.<p><a href='/help/developmental_stage' target='_top'>More...</a></p>Developmental stagei

Expressed both maternally and zygotically. Expression decreases from the mid-blastula stages onwards before increasing again at the start of gastrulation.1 Publication

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSDARG00000069006 Expressed in 28 organ(s), highest expression level in mature ovarian follicle

ExpressionAtlas, Differential and Baseline Expression

More...
ExpressionAtlasi
O13168 baseline

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

GO - Molecular functioni

Protein-protein interaction databases

STRING: functional protein association networks

More...
STRINGi
7955.ENSDARP00000109120

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section indicates the positions and types of repeated sequence motifs or repeated domains within the protein.<p><a href='/help/repeat' target='_top'>More...</a></p>Repeati483 – 521WD 1Add BLAST39
Repeati529 – 568WD 2Add BLAST40
Repeati573 – 612WD 3Add BLAST40
Repeati615 – 654WD 4Add BLAST40
Repeati656 – 695WD 5Add BLAST40
Repeati697 – 736WD 6Add BLAST40
Repeati738 – 771WD 7Add BLAST34

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni1 – 141Q domainBy similarityAdd BLAST141
Regioni142 – 209GP domainBy similarityAdd BLAST68
Regioni210 – 278CcN domainBy similarityAdd BLAST69
Regioni279 – 451SP domainBy similarityAdd BLAST173

Motif

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section describes a short (usually not more than 20 amino acids) conserved sequence motif of biological significance.<p><a href='/help/motif' target='_top'>More...</a></p>Motifi235 – 238Nuclear localization signalSequence analysis4

<p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the WD repeat Groucho/TLE family.Curated

Keywords - Domaini

Repeat, WD repeat

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG0639 Eukaryota
ENOG410XPX3 LUCA

Ensembl GeneTree

More...
GeneTreei
ENSGT00950000182705

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
HOG000293211

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
O13168

Identification of Orthologs from Complete Genome Data

More...
OMAi
HDLDHRE

Database of Orthologous Groups

More...
OrthoDBi
546143at2759

TreeFam database of animal gene trees

More...
TreeFami
TF314167

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
2.130.10.10, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR005617 Groucho/TLE_N
IPR009146 Groucho_enhance
IPR015943 WD40/YVTN_repeat-like_dom_sf
IPR001680 WD40_repeat
IPR019775 WD40_repeat_CS
IPR017986 WD40_repeat_dom
IPR036322 WD40_repeat_dom_sf

The PANTHER Classification System

More...
PANTHERi
PTHR10814 PTHR10814, 1 hit

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF03920 TLE_N, 1 hit
PF00400 WD40, 2 hits

Protein Motif fingerprint database; a protein domain database

More...
PRINTSi
PR01850 GROUCHOFAMLY

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00320 WD40, 7 hits

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF50978 SSF50978, 1 hit

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS00678 WD_REPEATS_1, 2 hits
PS50082 WD_REPEATS_2, 2 hits
PS50294 WD_REPEATS_REGION, 2 hits

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequence (1+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry has 1 described isoform and 2 potential isoforms that are computationally mapped.Show allAlign All

O13168-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MYPQGRHPAP HQPGQPGFKF TVAESCDRIK DEFQFLQAQY HSLKVEYDKL
60 70 80 90 100
ANEKTEMQRH YVMYYEMSYG LNIEMHKQTE IAKRLNAILA QIMPFLSQEH
110 120 130 140 150
QQQVAQAVER AKQVTMTELN AIIGVRGLPN LPLTQQQLQA QHLSHAAHGP
160 170 180 190 200
PVQLPPHPSG LQPPGIPPVT GSGSGLLALG ALGSQAHLPV KDEKNHHDLE
210 220 230 240 250
HRERESSTNN SVSPSDSLRA SEKHRGSSEY SLDPKKRRVE EKDNMSRYDS
260 270 280 290 300
DGDKSDDLVV DVSNEDPATP RVSPSHSPPE NGLDKARALK KDAPNSPASV
310 320 330 340 350
ASSGSTPSSK AKDHPHNDKS STPGLKSNTP TPRNDAPTPG TSNTPGLRPH
360 370 380 390 400
PGKPPGMEAL TAPALRTPLS IAPPYGTPFM MGHHPEMNGS LTSPGVYPGL
410 420 430 440 450
HISPQMSAAA AAAYGRTHMP GFDPHPHMRA PVLPASLTSI PGGKPAYSFH
460 470 480 490 500
VSADGQMQPV PFPPDALIGP GIPRHARQIN TLSHGEVVCA VTISNPTRHV
510 520 530 540 550
YTGGKGCVKI WDISQPGSKS PVSQLDCLNR DNYIRSCKLL PDGRTLIVGG
560 570 580 590 600
EASTLTIWDL ASQTPRIKAE LTSSAPACYA LAISPDAKVC FSCCSDGNIA
610 620 630 640 650
VWDLHNQTLV RQFQGHTDGA SCIDISHDGT KLWTGGLDNT VRSWDLREGR
660 670 680 690 700
QLQQHDFTSQ IFSLGYCPTG EWLAVGMESS NVEVLHHTKP DKYQLHLHES
710 720 730 740 750
CVLSLKFAYC GKWFVSTGKD NLLNAWRTPY GASIFQSKES SSVLSCDISA
760 770
DDKYIVTGSG DKKATVYEVI Y
Length:771
Mass (Da):83,789
Last modified:November 22, 2017 - v2
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i3B9CEB203826E458
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There are 2 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
A0A2R8QDQ1A0A2R8QDQ1_DANRE
Transducin-like enhancer protein 3-...
tle3b
756Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A1D5NSU2A0A1D5NSU2_DANRE
Transducin-like enhancer protein 3-...
tle3b
104Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti332P → H in AAB57808 (PubMed:27747413).Curated1
Sequence conflicti332P → H in CAA73070 (PubMed:27747413).Curated1
Sequence conflicti350H → R in AAB57808 (PubMed:27747413).Curated1
Sequence conflicti350H → R in CAA73070 (PubMed:27747413).Curated1
Sequence conflicti398P → A in AAB57808 (PubMed:27747413).Curated1
Sequence conflicti398P → A in CAA73070 (PubMed:27747413).Curated1
Sequence conflicti418H → S in AAB57808 (PubMed:27747413).Curated1
Sequence conflicti418H → S in CAA73070 (PubMed:27747413).Curated1
Sequence conflicti548V → A in AAB57808 (PubMed:27747413).Curated1
Sequence conflicti548V → A in CAA73070 (PubMed:27747413).Curated1
Sequence conflicti552A → V in AAB57808 (PubMed:27747413).Curated1
Sequence conflicti552A → V in CAA73070 (PubMed:27747413).Curated1
Sequence conflicti630T → P in AAB57808 (PubMed:27747413).Curated1
Sequence conflicti630T → P in CAA73070 (PubMed:27747413).Curated1
Sequence conflicti707F → S in AAB57808 (PubMed:27747413).Curated1
Sequence conflicti707F → S in CAA73070 (PubMed:27747413).Curated1

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AB040707 mRNA Translation: BAB40698.1
AL954672 Genomic DNA No translation available.
BC162571 mRNA Translation: AAI62571.1
U96451 mRNA Translation: AAB57808.1
Y12467 mRNA Translation: CAA73070.1

NCBI Reference Sequences

More...
RefSeqi
NP_571855.1, NM_131780.1

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENSDART00000130553; ENSDARP00000109120; ENSDARG00000069006
ENSDART00000175980; ENSDARP00000143498; ENSDARG00000069006

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
100007463

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
dre:100007463

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AB040707 mRNA Translation: BAB40698.1
AL954672 Genomic DNA No translation available.
BC162571 mRNA Translation: AAI62571.1
U96451 mRNA Translation: AAB57808.1
Y12467 mRNA Translation: CAA73070.1
RefSeqiNP_571855.1, NM_131780.1

3D structure databases

Database of comparative protein structure models

More...
ModBasei
Search...

SWISS-MODEL Interactive Workspace

More...
SWISS-MODEL-Workspacei
Submit a new modelling project...

Protein-protein interaction databases

STRINGi7955.ENSDARP00000109120

PTM databases

iPTMnetiO13168

Proteomic databases

PaxDbiO13168
PRIDEiO13168

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSDART00000130553; ENSDARP00000109120; ENSDARG00000069006
ENSDART00000175980; ENSDARP00000143498; ENSDARG00000069006
GeneIDi100007463
KEGGidre:100007463

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
100007463
ZFINiZDB-GENE-990415-85 tle3b

Phylogenomic databases

eggNOGiKOG0639 Eukaryota
ENOG410XPX3 LUCA
GeneTreeiENSGT00950000182705
HOGENOMiHOG000293211
InParanoidiO13168
OMAiHDLDHRE
OrthoDBi546143at2759
TreeFamiTF314167

Enzyme and pathway databases

ReactomeiR-DRE-201722 Formation of the beta-catenin:TCF transactivating complex
R-DRE-3769402 Deactivation of the beta-catenin transactivating complex
R-DRE-4641265 Repression of WNT target genes
R-DRE-9018519 Estrogen-dependent gene expression

Miscellaneous databases

Protein Ontology

More...
PROi
PR:O13168

Gene expression databases

BgeeiENSDARG00000069006 Expressed in 28 organ(s), highest expression level in mature ovarian follicle
ExpressionAtlasiO13168 baseline

Family and domain databases

Gene3Di2.130.10.10, 1 hit
InterProiView protein in InterPro
IPR005617 Groucho/TLE_N
IPR009146 Groucho_enhance
IPR015943 WD40/YVTN_repeat-like_dom_sf
IPR001680 WD40_repeat
IPR019775 WD40_repeat_CS
IPR017986 WD40_repeat_dom
IPR036322 WD40_repeat_dom_sf
PANTHERiPTHR10814 PTHR10814, 1 hit
PfamiView protein in Pfam
PF03920 TLE_N, 1 hit
PF00400 WD40, 2 hits
PRINTSiPR01850 GROUCHOFAMLY
SMARTiView protein in SMART
SM00320 WD40, 7 hits
SUPFAMiSSF50978 SSF50978, 1 hit
PROSITEiView protein in PROSITE
PS00678 WD_REPEATS_1, 2 hits
PS50082 WD_REPEATS_2, 2 hits
PS50294 WD_REPEATS_REGION, 2 hits

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiTLE3B_DANRE
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: O13168
Secondary accession number(s): Q98TH2
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: July 15, 1998
Last sequence update: November 22, 2017
Last modified: May 8, 2019
This is version 127 of the entry and version 2 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.

Do not show this banner again