UniProtKB - O09118 (NET1_MOUSE)

BLAST

>sp|O09118|NET1_MOUSE Netrin-1 OS=Mus musculus OX=10090 GN=Ntn1 PE=1 SV=3
MMRAVWEALAALAAVACLVGAVRGGPGLSMFAGQAAQPDPCSDENGHPRRCIPDFVNAAF
GKDVRVSSTCGRPPARYCVVSERGEERLRSCHLCNSSDPKKAHPPAFLTDLNNPHNLTCW
QSENYLQFPHNVTLTLSLGKKFEVTYVSLQFCSPRPESMAIYKSMDYGRTWVPFQFYSTQ
CRKMYNRPHRAPITKQNEQEAVCTDSHTDMRPLSGGLIAFSTLDGRPSAHDFDNSPVLQD
WVTATDIRVAFSRLHTFGDENEDDSELARDSYYYAVSDLQVGGRCKCNGHAARCVRDRDD
SLVCDCRHNTAGPECDRCKPFHYDRPWQRATAREANECVACNCNLHARRCRFNMELYKLS
GRKSGGVCLNCRHNTAGRHCHYCKEGFYRDMGKPITHRKACKACDCHPVGAAGKTCNQTT
GQCPCKDGVTGITCNRCAKGYQQSRSPIAPCIKIPVAPPTTAASSVEEPEDCDSYCKASK
GKLKMNMKKYCRKDYAVQIHILKADKAGDWWKFTVNIISVYKQGTSRIRRGDQSLWIRSR
DIACKCPKIKPLKKYLLLGNAEDSPDQSGIVADKSSLVIQWRDTWARRLRKFQQREKKGK
CKKA

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History
Entry version 160 (07 Nov 2018)
Sequence version 3 (27 Jul 2011)
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Protein

Netrin-1

Gene

Ntn1

Organism

Mus musculus (Mouse)

Status

Reviewed-Annotation score: -Experimental evidence at protein levelⁱ

Functionⁱ

Netrins control guidance of CNS commissural axons and peripheral motor axons. Its association with either DCC or some UNC5 receptors will lead to axon attraction or repulsion, respectively. It also serve as a survival factor via its association with its receptors which prevent the initiation of apoptosis. Involved in colorectal tumorigenesis by regulating apoptosis (By similarity).By similarity2 Publications

GO - Molecular functionⁱ

extracellular matrix structural constituent
Source: BHF-UCL
Inferred from high throughput direct assayⁱ
- 22159717

View the complete GO annotation on QuickGO ...

GO - Biological processⁱ

anterior/posterior axon guidance
Source: MGI
Inferred from mutant phenotypeⁱ
- 18479186
apoptotic process Source: UniProtKB-KW
axon guidance
Source: MGI
Inferred from direct assayⁱ
axonogenesis
Source: MGI
Inferred from direct assayⁱ
- 10908620
Cdc42 protein signal transduction Source: UniProtKB
cell-cell adhesion
Source: MGI
Inferred from genetic interactionⁱ
- 16439476
inner ear morphogenesis
Source: MGI
Inferred from mutant phenotypeⁱ
- 17616930
mammary gland development
Source: MGI
Inferred from genetic interactionⁱ
- 18425773
mammary gland duct morphogenesis
Source: MGI
Inferred from genetic interactionⁱ
- 16439476
negative regulation of axon extension
Source: MGI
Inferred from direct assayⁱ
- 10704383
neuron migration
Source: MGI
Inferred from mutant phenotypeⁱ
- 14750959
- 16267219
nuclear migration
Source: MGI
Inferred from direct assayⁱ
- 12051827
positive regulation of axon extension
Source: MGI
Inferred from direct assayⁱ
- 10704383
positive regulation of cell motility Source: UniProtKB
positive regulation of cell proliferation
Source: MGI
Inferred from mutant phenotypeⁱ
- 16481423
Ras protein signal transduction Source: UniProtKB
regulation of cell migration
Source: MGI
Inferred from direct assayⁱ
- 10704383
regulation of synapse assembly
Source: SynGO
Inferred from direct assayⁱ
- 24174661
substrate-dependent cell migration, cell extension Source: UniProtKB

View the complete GO annotation on QuickGO ...

Keywordsⁱ

Biological process	Apoptosis

Biological process

Apoptosis

Enzyme and pathway databases

Reactomeⁱ	R-MMU-373752 Netrin-1 signaling R-MMU-418885 DCC mediated attractive signaling

Reactomeⁱ

R-MMU-373752 Netrin-1 signaling
R-MMU-418885 DCC mediated attractive signaling

Names & Taxonomyⁱ

Protein namesⁱ	Recommended name: Netrin-1
Gene namesⁱ	Name:Ntn1
Organismⁱ	Mus musculus (Mouse)
Taxonomic identifierⁱ	10090 [NCBI]
Taxonomic lineageⁱ	cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Dipnotetrapodomorpha › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Boreoeutheria › Euarchontoglires › Glires › Rodentia › Myomorpha › Muroidea › Muridae › Murinae › Mus › Mus
Proteomesⁱ	UP000000589 Componentⁱ: Chromosome 11

Organism-specific databases

MGIⁱ	MGI:105088 Ntn1

Keywords - Cellular componentⁱ

Extracellular matrix, Secreted

PTM / Processingⁱ

Molecule processing

Feature key	Position(s)	DescriptionActions	Graphical view	Length
Signal peptideⁱ	1 – 24	Sequence analysisAdd BLAST		24
ChainⁱPRO_0000017083	25 – 604	Netrin-1Add BLAST		580

Amino acid modifications

Feature key	Position(s)	DescriptionActions	Length
Glycosylationⁱ	95	N-linked (GlcNAc...) asparagineSequence analysis	1
Glycosylationⁱ	116	N-linked (GlcNAc...) asparagineSequence analysis	1
Disulfide bondⁱ	119 ↔ 152	By similarity
Glycosylationⁱ	131	N-linked (GlcNAc...) asparagineSequence analysis	1
Disulfide bondⁱ	285 ↔ 294	By similarity
Disulfide bondⁱ	287 ↔ 304	By similarity
Disulfide bondⁱ	306 ↔ 315	By similarity
Disulfide bondⁱ	318 ↔ 338	By similarity
Disulfide bondⁱ	341 ↔ 350	By similarity
Disulfide bondⁱ	343 ↔ 368	By similarity
Disulfide bondⁱ	371 ↔ 380	By similarity
Disulfide bondⁱ	383 ↔ 401	By similarity
Disulfide bondⁱ	404 ↔ 416	By similarity
Disulfide bondⁱ	406 ↔ 423	By similarity
Glycosylationⁱ	417	N-linked (GlcNAc...) asparagineSequence analysis	1
Disulfide bondⁱ	425 ↔ 434	By similarity
Disulfide bondⁱ	437 ↔ 451	By similarity
Disulfide bondⁱ	472 ↔ 544	By similarity
Disulfide bondⁱ	491 ↔ 601	By similarity

Keywords - PTMⁱ

Disulfide bond, Glycoprotein

Proteomic databases

MaxQB - The MaxQuant DataBase More...MaxQBⁱ	O09118
PaxDbⁱ	O09118
PeptideAtlas More...PeptideAtlasⁱ	O09118
PRIDEⁱ	O09118

PTM databases

PhosphoSitePlusⁱ	O09118

PhosphoSitePlusⁱ

O09118

Expressionⁱ

Tissue specificityⁱ

In the embryo, widely expressed in the developing nervous system and in mesodermal tissues.1 Publication

Gene expression databases

Bgeeⁱ	ENSMUSG00000020902 Expressed in 281 organ(s), highest expression level in aorta
CleanExⁱ	MM_NTN1
ExpressionAtlasⁱ	O09118 baseline and differential
Genevisibleⁱ	O09118 MM

Interactionⁱ

Subunit structureⁱ

Binds to its receptors; DCC, UNC5A, UNC5B, UNC5C and probably UNC5D (By similarity). Binds to its receptor; DSCAM.By similarity

Binary interactionsⁱ

With	Entry	#Exp.	IntAct	Notes
Unc5b	Q8K1S3-1	4	EBI-1798844,EBI-11658250

With

Entry

#Exp.

IntAct

Notes

Unc5b

Q8K1S3-1

EBI-1798844,EBI-11658250

Protein-protein interaction databases

IntActⁱ	O09118, 4 interactors
STRINGⁱ	10090.ENSMUSP00000021284

Structureⁱ

Secondary structure

Legend: HelixTurnBeta strandPDB Structure known for this area

Feature key	Position(s)	DescriptionActions	Length
Beta strandⁱ	40 – 42	Combined sources	3
Turnⁱ	58 – 61	Combined sources	4
Beta strandⁱ	65 – 67	Combined sources	3
Beta strandⁱ	75 – 81	Combined sources	7
Beta strandⁱ	83 – 85	Combined sources	3
Beta strandⁱ	88 – 94	Combined sources	7
Turnⁱ	99 – 101	Combined sources	3
Helixⁱ	105 – 108	Combined sources	4
Beta strandⁱ	132 – 153	Combined sources	22
Beta strandⁱ	157 – 166	Combined sources	10
Beta strandⁱ	172 – 177	Combined sources	6
Helixⁱ	181 – 185	Combined sources	5
Beta strandⁱ	197 – 199	Combined sources	3
Helixⁱ	206 – 208	Combined sources	3
Beta strandⁱ	213 – 215	Combined sources	3
Beta strandⁱ	217 – 221	Combined sources	5
Turnⁱ	222 – 225	Combined sources	4
Helixⁱ	227 – 234	Combined sources	8
Helixⁱ	236 – 241	Combined sources	6
Beta strandⁱ	243 – 253	Combined sources	11
Beta strandⁱ	275 – 285	Combined sources	11
Beta strandⁱ	294 – 296	Combined sources	3
Beta strandⁱ	302 – 304	Combined sources	3
Turnⁱ	312 – 315	Combined sources	4
Beta strandⁱ	348 – 352	Combined sources	5
Helixⁱ	354 – 359	Combined sources	6
Beta strandⁱ	366 – 370	Combined sources	5
Beta strandⁱ	373 – 376	Combined sources	4
Turnⁱ	377 – 380	Combined sources	4
Beta strandⁱ	387 – 389	Combined sources	3
Beta strandⁱ	401 – 403	Combined sources	3
Turnⁱ	408 – 410	Combined sources	3
Turnⁱ	418 – 420	Combined sources	3
Turnⁱ	431 – 434	Combined sources	4
Beta strandⁱ	441 – 443	Combined sources	3
Beta strandⁱ	451 – 453	Combined sources	3

Show more details

3D structure databases

ProteinModelPortalⁱ	O09118
SMRⁱ	O09118
ModBaseⁱ	Search...
MobiDBⁱ	Search...

Family & Domainsⁱ

Domains and Repeats

Feature key	Position(s)	DescriptionActions	Length
Domainⁱ	47 – 284	Laminin N-terminalPROSITE-ProRule annotationAdd BLAST	238
Domainⁱ	285 – 340	Laminin EGF-like 1PROSITE-ProRule annotationAdd BLAST	56
Domainⁱ	341 – 403	Laminin EGF-like 2PROSITE-ProRule annotationAdd BLAST	63
Domainⁱ	404 – 453	Laminin EGF-like 3PROSITE-ProRule annotationAdd BLAST	50
Domainⁱ	472 – 601	NTRPROSITE-ProRule annotationAdd BLAST	130

Motif

Feature key	Position(s)	DescriptionActions	Graphical view	Length
Motifⁱ	530 – 532	Cell attachment siteSequence analysis		3

Keywords - Domainⁱ

Laminin EGF-like domain, Repeat, Signal

Phylogenomic databases

eggNOGⁱ	KOG3512 Eukaryota ENOG410XS7U LUCA
Ensembl GeneTree More...GeneTreeⁱ	ENSGT00890000139348
HOGENOMⁱ	HOG000286017
HOVERGENⁱ	HBG006464
InParanoidⁱ	O09118
KEGG Orthology (KO) More...KOⁱ	K06843
OMAⁱ	DQFLWVR
Database of Orthologous Groups More...OrthoDBⁱ	EOG091G005L
TreeFamⁱ	TF352481

Family and domain databases

Gene3Dⁱ	2.60.120.1490, 1 hit
InterProⁱ	View protein in InterPro IPR008979 Galactose-bd-like_sf IPR002049 Laminin_EGF IPR008211 Laminin_N IPR038684 Laminin_N_sf IPR001134 Netrin_domain IPR018933 Netrin_module_non-TIMP IPR008993 TIMP-like_OB-fold
Pfam protein domain database More...Pfamⁱ	View protein in Pfam PF00053 Laminin_EGF, 3 hits PF00055 Laminin_N, 1 hit PF01759 NTR, 1 hit
SMARTⁱ	View protein in SMART SM00643 C345C, 1 hit SM00180 EGF_Lam, 3 hits SM00136 LamNT, 1 hit
SUPFAMⁱ	SSF49785 SSF49785, 1 hit SSF50242 SSF50242, 1 hit
PROSITEⁱ	View protein in PROSITE PS00022 EGF_1, 2 hits PS01248 EGF_LAM_1, 3 hits PS50027 EGF_LAM_2, 3 hits PS51117 LAMININ_NTER, 1 hit PS50189 NTR, 1 hit

Sequence (1+)ⁱ

Sequence statusⁱ: Complete.

Sequence processingⁱ: The displayed sequence is further processed into a mature form.

This entry has 1 described isoform and 1 potential isoform that is computationally mapped.Show all Align All

O09118-1 [UniParc]FASTA Add to basket

« Hide

        10         20         30         40         50
MMRAVWEALA ALAAVACLVG AVRGGPGLSM FAGQAAQPDP CSDENGHPRR 
        60         70         80         90        100
CIPDFVNAAF GKDVRVSSTC GRPPARYCVV SERGEERLRS CHLCNSSDPK 
       110        120        130        140        150
KAHPPAFLTD LNNPHNLTCW QSENYLQFPH NVTLTLSLGK KFEVTYVSLQ 
       160        170        180        190        200
FCSPRPESMA IYKSMDYGRT WVPFQFYSTQ CRKMYNRPHR APITKQNEQE 
       210        220        230        240        250
AVCTDSHTDM RPLSGGLIAF STLDGRPSAH DFDNSPVLQD WVTATDIRVA 
       260        270        280        290        300
FSRLHTFGDE NEDDSELARD SYYYAVSDLQ VGGRCKCNGH AARCVRDRDD 
       310        320        330        340        350
SLVCDCRHNT AGPECDRCKP FHYDRPWQRA TAREANECVA CNCNLHARRC 
       360        370        380        390        400
RFNMELYKLS GRKSGGVCLN CRHNTAGRHC HYCKEGFYRD MGKPITHRKA 
       410        420        430        440        450
CKACDCHPVG AAGKTCNQTT GQCPCKDGVT GITCNRCAKG YQQSRSPIAP 
       460        470        480        490        500
CIKIPVAPPT TAASSVEEPE DCDSYCKASK GKLKMNMKKY CRKDYAVQIH 
       510        520        530        540        550
ILKADKAGDW WKFTVNIISV YKQGTSRIRR GDQSLWIRSR DIACKCPKIK 
       560        570        580        590        600
PLKKYLLLGN AEDSPDQSGI VADKSSLVIQ WRDTWARRLR KFQQREKKGK 

CKKA

Length:604

Mass (Da):67,810

Last modified:July 27, 2011 - v3

Checksum:ⁱ135120DB6F0482F3

Computationally mapped potential isoform sequencesⁱ

There is 1 potential isoform mapped to this entry.BLAST Align Show all Add to basket

	Entry	Entry name		Protein names	Gene names	Length	Annotation

	B0QZL0	B0QZL0_MOUSE		Netrin-1 Netrin-1	Ntn1	159	Annotation score:

Experimental Info

Feature key	Position(s)	DescriptionActions	Length
Sequence conflictⁱ	24	Missing in AAC52971 (PubMed:8978605).Curated	1
Sequence conflictⁱ	88	L → V in AAC52971 (PubMed:8978605).Curated	1
Sequence conflictⁱ	88	L → V in AAD28602 (PubMed:10381568).Curated	1
Sequence conflictⁱ	466	V → A in AAD28602 (PubMed:10381568).Curated	1

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	U65418 mRNA Translation: AAC52971.1 AF128865 mRNA Translation: AAD28602.1 AL669842, AL606831, AL662894 Genomic DNA Translation: CAI24775.1 AL606831, AL662894, AL669842 Genomic DNA Translation: CAI25691.1 AL662894, AL606831, AL669842 Genomic DNA Translation: CAI25793.1 CH466601 Genomic DNA Translation: EDL10446.1 BC141294 mRNA Translation: AAI41295.1 U23505 mRNA Translation: AAA87938.1
The Consensus CDS (CCDS) project More...CCDSⁱ	CCDS24864.1
NCBI Reference Sequences More...RefSeqⁱ	NP_032770.2, NM_008744.2
UniGeneⁱ	Mm.39095

Genome annotation databases

Ensemblⁱ	ENSMUST00000021284; ENSMUSP00000021284; ENSMUSG00000020902 ENSMUST00000108674; ENSMUSP00000104314; ENSMUSG00000020902
GeneIDⁱ	18208
KEGGⁱ	mmu:18208
UCSC genome browser More...UCSCⁱ	uc007jnm.1 mouse

Similar proteinsⁱ

100% Identity
90% Identity
50% Identity

Protein	Similar proteins		Species	Score	Length	Source
O09118	Netrin-1 (Fragment)		MOUSE		159	UniRef100_O09118

Protein	Similar proteins		Species	Score	Length	Source
O09118	Netrin-1	)	HUMAN		604	UniRef90_O09118
Netrin-1		RAT		604
Netrin-1		PIG		600
Netrin-1 (Fragment)		MOUSE		159
netrin-1		Florida manatee		690
+102

Protein	Similar proteins		Species	Score	Length	Source
O09118	Netrin-1		RAT		604	UniRef50_O09118
Netrin-1	)	HUMAN		604
Netrin-1		PIG		600
Netrin-1	)	CHICK		606
Netrin-1 (Fragment)		MOUSE		159
+495

Cross-referencesⁱ

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	U65418 mRNA Translation: AAC52971.1 AF128865 mRNA Translation: AAD28602.1 AL669842, AL606831, AL662894 Genomic DNA Translation: CAI24775.1 AL606831, AL662894, AL669842 Genomic DNA Translation: CAI25691.1 AL662894, AL606831, AL669842 Genomic DNA Translation: CAI25793.1 CH466601 Genomic DNA Translation: EDL10446.1 BC141294 mRNA Translation: AAI41295.1 U23505 mRNA Translation: AAA87938.1
CCDSⁱ	CCDS24864.1
RefSeqⁱ	NP_032770.2, NM_008744.2
UniGeneⁱ	Mm.39095

3D structure databases

Select the link destinations: Protein Data Bank Europe More...PDBeⁱ Protein Data Bank RCSB More...RCSB PDBⁱ Protein Data Bank Japan More...PDBjⁱ Links Updated	PDB entry	Method	Resolution (Å)	Chain	Positions	PDBsum
	4OVE	X-ray	2.64	A	23-457	[»]
ProteinModelPortalⁱ	O09118
SMRⁱ	O09118
ModBaseⁱ	Search...
MobiDBⁱ	Search...

Protein-protein interaction databases

IntActⁱ	O09118, 4 interactors
STRINGⁱ	10090.ENSMUSP00000021284

PTM databases

PhosphoSitePlusⁱ	O09118

PhosphoSitePlusⁱ

O09118

Proteomic databases

MaxQBⁱ	O09118
PaxDbⁱ	O09118
PeptideAtlasⁱ	O09118
PRIDEⁱ	O09118

Protocols and materials databases

Structural Biology Knowledgebase	Search...

Structural Biology Knowledgebase

Search...

Genome annotation databases

Ensemblⁱ	ENSMUST00000021284; ENSMUSP00000021284; ENSMUSG00000020902 ENSMUST00000108674; ENSMUSP00000104314; ENSMUSG00000020902
GeneIDⁱ	18208
KEGGⁱ	mmu:18208
UCSCⁱ	uc007jnm.1 mouse

Organism-specific databases

CTDⁱ	9423
MGIⁱ	MGI:105088 Ntn1

Phylogenomic databases

eggNOGⁱ	KOG3512 Eukaryota ENOG410XS7U LUCA
GeneTreeⁱ	ENSGT00890000139348
HOGENOMⁱ	HOG000286017
HOVERGENⁱ	HBG006464
InParanoidⁱ	O09118
KOⁱ	K06843
OMAⁱ	DQFLWVR
OrthoDBⁱ	EOG091G005L
TreeFamⁱ	TF352481

Enzyme and pathway databases

Reactomeⁱ	R-MMU-373752 Netrin-1 signaling R-MMU-418885 DCC mediated attractive signaling

Reactomeⁱ

R-MMU-373752 Netrin-1 signaling
R-MMU-418885 DCC mediated attractive signaling

Miscellaneous databases

Protein Ontology More...PROⁱ	PR:O09118
SOURCEⁱ	Search...

Gene expression databases

Bgeeⁱ	ENSMUSG00000020902 Expressed in 281 organ(s), highest expression level in aorta
CleanExⁱ	MM_NTN1
ExpressionAtlasⁱ	O09118 baseline and differential
Genevisibleⁱ	O09118 MM

Family and domain databases

Gene3Dⁱ	2.60.120.1490, 1 hit
InterProⁱ	View protein in InterPro IPR008979 Galactose-bd-like_sf IPR002049 Laminin_EGF IPR008211 Laminin_N IPR038684 Laminin_N_sf IPR001134 Netrin_domain IPR018933 Netrin_module_non-TIMP IPR008993 TIMP-like_OB-fold
Pfamⁱ	View protein in Pfam PF00053 Laminin_EGF, 3 hits PF00055 Laminin_N, 1 hit PF01759 NTR, 1 hit
SMARTⁱ	View protein in SMART SM00643 C345C, 1 hit SM00180 EGF_Lam, 3 hits SM00136 LamNT, 1 hit
SUPFAMⁱ	SSF49785 SSF49785, 1 hit SSF50242 SSF50242, 1 hit
PROSITEⁱ	View protein in PROSITE PS00022 EGF_1, 2 hits PS01248 EGF_LAM_1, 3 hits PS50027 EGF_LAM_2, 3 hits PS51117 LAMININ_NTER, 1 hit PS50189 NTR, 1 hit
ProtoNetⁱ	Search...

Entry informationⁱ

Entry nameⁱ	NET1_MOUSE
Accessionⁱ	O09118Primary (citable) accession number: O09118 Secondary accession number(s): B1ARR0, Q60832, Q9QY50
Entry historyⁱ	Integrated into UniProtKB/Swiss-Prot:	November 15, 2002
	Last sequence update:	July 27, 2011
	Last modified:	November 7, 2018
	This is version 160 of the entry and version 3 of the sequence. See complete history.
Entry statusⁱ	Reviewed (UniProtKB/Swiss-Prot)
Annotation program	Chordata Protein Annotation Program

Miscellaneousⁱ

Keywords - Technical termⁱ

3D-structure, Complete proteome, Reference proteome

Documents

MGD cross-references
Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
PDB cross-references
Index of Protein Data Bank (PDB) cross-references

UniProtKB

UniParc

Help

UniRef

Proteomes

Annotation systems

Supporting data

UniProtKB - O09118 (NET1_MOUSE)

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Netrin-1

Ntn1

Select a section on the left to see content.

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

Enzyme and pathway databases

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

Organism-specific databases

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted

Extracellular region or secreted

Other locations

Keywords - Cellular componenti

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Amino acid modifications

Keywords - PTMi

Proteomic databases

PTM databases

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

Secondary structure

3D structure databases

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Motif

Keywords - Domaini

Phylogenomic databases

Family and domain databases

Experimental Info

Sequence databases

Genome annotation databases

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

3D structure databases

Protein-protein interaction databases

PTM databases

Proteomic databases

Protocols and materials databases

Genome annotation databases

Organism-specific databases

Phylogenomic databases

Enzyme and pathway databases

Miscellaneous databases

Gene expression databases

Family and domain databases

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Documents

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Functionⁱ

GO - Molecular functionⁱ

GO - Biological processⁱ

Names & Taxonomyⁱ

Subcellular locationⁱ

Keywords - Cellular componentⁱ

PTM / Processingⁱ

Keywords - PTMⁱ

Expressionⁱ

Interactionⁱ

Structureⁱ

Family & Domainsⁱ

Keywords - Domainⁱ

Cross-referencesⁱ

Entry informationⁱ

Miscellaneousⁱ

Keywords - Technical termⁱ