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Protein
Submitted name:

Neurogenin 3

Gene

Neurog3

Organism
Rattus norvegicus (Rat)
Status
Unreviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

GO - Biological processi

  • endocrine pancreas development Source: InterPro
  • epithelial cell differentiation Source: Ensembl
  • forebrain development Source: RGD
  • hindbrain development Source: RGD
  • positive regulation of cell differentiation Source: RGD
  • positive regulation of DNA binding transcription factor activity Source: Ensembl
  • positive regulation of neuron differentiation Source: RGD
  • regulation of dendrite morphogenesis Source: Ensembl
  • regulation of transcription, DNA-templated Source: RGD
  • spinal cord development Source: RGD
  • transdifferentiation Source: Ensembl

Enzyme and pathway databases

ReactomeiR-RNO-210746 Regulation of gene expression in endocrine-committed (NEUROG3+) progenitor cells

Names & Taxonomyi

Protein namesi
Submitted name:
Neurogenin 3Imported
Submitted name:
RelaxImported
Gene namesi
Name:Neurog3Imported
ORF Names:rCG_21967Imported
OrganismiRattus norvegicus (Rat)Imported
Taxonomic identifieri10116 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeRattus
Proteomesi
  • UP000002494 Componenti: Chromosome 20

Organism-specific databases

RGDi631350 Neurog3

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Expressioni

Gene expression databases

BgeeiENSRNOG00000024413

Interactioni

GO - Molecular functioni

Protein-protein interaction databases

STRINGi10116.ENSRNOP00000000661

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini83 – 135BHLHInterPro annotationAdd BLAST53

Phylogenomic databases

eggNOGiKOG3898 Eukaryota
ENOG4111U26 LUCA
GeneTreeiENSGT00680000099860
HOGENOMiHOG000063655
HOVERGENiHBG031743
KOiK08028
OMAiRKKANDR
OrthoDBiEOG091G0PNH
TreeFamiTF315153

Family and domain databases

CDDicd00083 HLH, 1 hit
Gene3Di4.10.280.10, 1 hit
InterProiView protein in InterPro
IPR011598 bHLH_dom
IPR036638 HLH_DNA-bd_sf
IPR032656 Ngn3
PANTHERiPTHR19290:SF94 PTHR19290:SF94, 1 hit
PfamiView protein in Pfam
PF00010 HLH, 1 hit
SMARTiView protein in SMART
SM00353 HLH, 1 hit
SUPFAMiSSF47459 SSF47459, 1 hit
PROSITEiView protein in PROSITE
PS50888 BHLH, 1 hit

Sequencei

Sequence statusi: Complete.

O08718-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAPHPLDAPT IQVSQETQQP FPGASDHEVL SSNSTPPSPT LVPRDCSEAE
60 70 80 90 100
AGDCRGTSRK LRARRGGRNR PKSELALSKQ RRSRRKKAND RERNRMHNLN
110 120 130 140 150
SALDALRGVL PTFPDDAKLT KIETLRFAHN YIWALTQTLR IADHSFYGPE
160 170 180 190 200
PPVPCGELGS PGGGSSGDWG SIYSPVSQAG SLSPTASLEE FPGLQVPSSP
210
SCLLPGTLVF SDFL
Length:214
Mass (Da):23,156
Last modified:July 1, 1997 - v1
Checksum:iC4F6D64E542E4305
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AABR07045018 Genomic DNA No translation available.
Y10619 mRNA Translation: CAA71630.1
CH474016 Genomic DNA Translation: EDL92993.1
RefSeqiNP_067732.1, NM_021700.1
UniGeneiRn.42927

Genome annotation databases

EnsembliENSRNOT00000000661; ENSRNOP00000000661; ENSRNOG00000024413
GeneIDi60329
KEGGirno:60329
UCSCiRGD:631350 rat

Similar proteinsi

Entry informationi

Entry nameiO08718_RAT
AccessioniPrimary (citable) accession number: O08718
Entry historyiIntegrated into UniProtKB/TrEMBL: July 1, 1997
Last sequence update: July 1, 1997
Last modified: July 18, 2018
This is version 121 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

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