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Protein

Histone-lysine N-methyltransferase 2B

Gene

Kmt2b

Organism
Mus musculus (Mouse)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

Histone methyltransferase. Methylates 'Lys-4' of histone H3. H3 'Lys-4' methylation represents a specific tag for epigenetic transcriptional activation. Plays a central role in beta-globin locus transcription regulation by being recruited by NFE2 (By similarity). Plays an important role in controlling bulk H3K4me during oocyte growth and preimplantation development. Required during the transcriptionally active period of oocyte growth for the establishment and/or maintenance of bulk H3K4 trimethylation (H3K4me3), global transcriptional silencing that preceeds resumption of meiosis, oocyte survival and normal zygotic genome activation.By similarity1 Publication

Caution

The human ortholog, KMT2B/MLL4, was first named MLL2 (see AC Q9UMN6). Thus, mouse Kmt2b/Mll4 is also often referred to as Mll2 and vice versa in the literature.Curated

Catalytic activityi

S-adenosyl-L-methionine + L-lysine-[histone] = S-adenosyl-L-homocysteine + N6-methyl-L-lysine-[histone].

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Binding sitei2583S-adenosyl-L-methioninePROSITE-ProRule annotation1
Binding sitei2585S-adenosyl-L-methioninePROSITE-ProRule annotation1
Binding sitei2627S-adenosyl-L-methioninePROSITE-ProRule annotation1
Metal bindingi2653ZincBy similarity1
Metal bindingi2701ZincBy similarity1
Binding sitei2702S-adenosyl-L-methioninePROSITE-ProRule annotation1
Metal bindingi2703ZincBy similarity1
Metal bindingi2708ZincBy similarity1

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
DNA bindingi37 – 44A.T hook 18
DNA bindingi110 – 117A.T hook 28
DNA bindingi357 – 365A.T hook 39
Zinc fingeri964 – 1011CXXC-typePROSITE-ProRule annotationAdd BLAST48
Zinc fingeri1207 – 1258PHD-type 1PROSITE-ProRule annotationAdd BLAST52
Zinc fingeri1255 – 1309PHD-type 2PROSITE-ProRule annotationAdd BLAST55
Zinc fingeri1341 – 1402PHD-type 3PROSITE-ProRule annotationAdd BLAST62
Zinc fingeri1584 – 1624C2HC pre-PHD-typePROSITE-ProRule annotationAdd BLAST41
Zinc fingeri1645 – 1692PHD-type 4PROSITE-ProRule annotationAdd BLAST48

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionChromatin regulator, DNA-binding, Methyltransferase, Transferase
Biological processTranscription, Transcription regulation
LigandMetal-binding, S-adenosyl-L-methionine, Zinc

Enzyme and pathway databases

ReactomeiR-MMU-3214841 PKMTs methylate histone lysines
R-MMU-8936459 RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function

Names & Taxonomyi

Protein namesi
Recommended name:
Histone-lysine N-methyltransferase 2B (EC:2.1.1.43)
Short name:
Lysine N-methyltransferase 2B
Alternative name(s):
Myeloid/lymphoid or mixed-lineage leukemia protein 4 homolog
Trithorax homolog 2
WW domain-binding protein 7
Short name:
WBP-7
Gene namesi
Name:Kmt2b
Synonyms:Mll2, Trx2, Wbp7
OrganismiMus musculus (Mouse)
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 7

Organism-specific databases

MGIiMGI:109565 Kmt2b

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Nucleus

Pathology & Biotechi

Disruption phenotypei

Females are infertile due to anovulation and follicle loss. Oocytes show reduced H3K4me3 but not H3K4me1, abnormal expression of pro-apoptotic genes and Iap elements (which may contribute to oocyte death and, ultimately, follicle loss) and fail to establish transcriptional repression.1 Publication

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Initiator methionineiRemovedBy similarity
ChainiPRO_00001248822 – 2713Histone-lysine N-methyltransferase 2BAdd BLAST2712

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Modified residuei2N-acetylalanineBy similarity1
Modified residuei113PhosphoserineCombined sources1
Modified residuei114PhosphoserineCombined sources1
Modified residuei118PhosphoserineCombined sources1
Cross-linki810Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)By similarity
Modified residuei826PhosphoserineBy similarity1
Modified residuei849PhosphoserineBy similarity1
Modified residuei866PhosphoserineBy similarity1
Modified residuei941PhosphoserineBy similarity1
Modified residuei1037PhosphoserineCombined sources1
Modified residuei1040PhosphoserineCombined sources1
Modified residuei1098PhosphoserineCombined sources1
Modified residuei1101PhosphoserineCombined sources1
Cross-linki1142Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)By similarity
Modified residuei1926PhosphoserineBy similarity1
Modified residuei1932PhosphoserineBy similarity1
Modified residuei2064PhosphothreonineCombined sources1
Modified residuei2079PhosphothreonineBy similarity1
Modified residuei2286PhosphoserineBy similarity1
Modified residuei2346PhosphoserineCombined sources1

Keywords - PTMi

Acetylation, Isopeptide bond, Phosphoprotein, Ubl conjugation

Proteomic databases

EPDiO08550
MaxQBiO08550
PaxDbiO08550
PRIDEiO08550

PTM databases

iPTMnetiO08550
PhosphoSitePlusiO08550

Expressioni

Gene expression databases

BgeeiENSMUSG00000006307 Expressed in 245 organ(s), highest expression level in secondary oocyte
CleanExiMM_WBP7
ExpressionAtlasiO08550 baseline and differential
GenevisibleiO08550 MM

Interactioni

Subunit structurei

Component of the menin-associated histone methyltransferase complex, at least composed of KMT2B/MLL4, ASH2L, RBBP5, WDR5, DPY30, MEN1; the complex interacts with POLR2A and POLR2B via MEN1. Interacts with NFE2. Interacts with KDM6B.By similarity

Protein-protein interaction databases

BioGridi217461, 3 interactors
CORUMiO08550
IntActiO08550, 1 interactor
MINTiO08550
STRINGi10090.ENSMUSP00000103789

Structurei

3D structure databases

ProteinModelPortaliO08550
SMRiO08550
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini1733 – 1789FYR N-terminalPROSITE-ProRule annotationAdd BLAST57
Domaini2409 – 2490FYR C-terminalPROSITE-ProRule annotationAdd BLAST82
Domaini2573 – 2689SETPROSITE-ProRule annotationAdd BLAST117
Domaini2697 – 2713Post-SETPROSITE-ProRule annotationAdd BLAST17

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Regioni2650 – 2651S-adenosyl-L-methionine bindingBy similarity2

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Compositional biasi6 – 106Gly-richAdd BLAST101
Compositional biasi272 – 300Gly-richAdd BLAST29
Compositional biasi347 – 410Glu-richAdd BLAST64
Compositional biasi414 – 776Pro-richAdd BLAST363
Compositional biasi1814 – 2296Pro-richAdd BLAST483

Sequence similaritiesi

Zinc finger

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Zinc fingeri964 – 1011CXXC-typePROSITE-ProRule annotationAdd BLAST48
Zinc fingeri1207 – 1258PHD-type 1PROSITE-ProRule annotationAdd BLAST52
Zinc fingeri1255 – 1309PHD-type 2PROSITE-ProRule annotationAdd BLAST55
Zinc fingeri1341 – 1402PHD-type 3PROSITE-ProRule annotationAdd BLAST62
Zinc fingeri1584 – 1624C2HC pre-PHD-typePROSITE-ProRule annotationAdd BLAST41
Zinc fingeri1645 – 1692PHD-type 4PROSITE-ProRule annotationAdd BLAST48

Keywords - Domaini

Repeat, Zinc-finger

Phylogenomic databases

eggNOGiKOG1084 Eukaryota
COG2940 LUCA
GeneTreeiENSGT00760000119228
HOGENOMiHOG000015326
HOVERGENiHBG100043
InParanoidiO08550
KOiK14959
TreeFamiTF319820

Family and domain databases

Gene3Di1.20.920.10, 1 hit
3.30.40.10, 3 hits
InterProiView protein in InterPro
IPR036427 Bromodomain-like_sf
IPR034732 EPHD
IPR003889 FYrich_C
IPR003888 FYrich_N
IPR016569 MeTrfase_trithorax
IPR003616 Post-SET_dom
IPR001214 SET_dom
IPR002857 Znf_CXXC
IPR011011 Znf_FYVE_PHD
IPR001965 Znf_PHD
IPR019787 Znf_PHD-finger
IPR013083 Znf_RING/FYVE/PHD
PfamiView protein in Pfam
PF05965 FYRC, 1 hit
PF05964 FYRN, 1 hit
PF00628 PHD, 2 hits
PF00856 SET, 1 hit
PF02008 zf-CXXC, 1 hit
PIRSFiPIRSF010354 Methyltransferase_trithorax, 1 hit
SMARTiView protein in SMART
SM00542 FYRC, 1 hit
SM00541 FYRN, 1 hit
SM00249 PHD, 4 hits
SM00508 PostSET, 1 hit
SM00317 SET, 1 hit
SUPFAMiSSF57903 SSF57903, 2 hits
PROSITEiView protein in PROSITE
PS51805 EPHD, 1 hit
PS51543 FYRC, 1 hit
PS51542 FYRN, 1 hit
PS50868 POST_SET, 1 hit
PS50280 SET, 1 hit
PS51058 ZF_CXXC, 1 hit
PS01359 ZF_PHD_1, 3 hits
PS50016 ZF_PHD_2, 3 hits

Sequence (1+)i

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

This entry has 1 described isoform and 2 potential isoforms that are computationally mapped.Show allAlign All

O08550-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MAAAAGGGSC PGPGSARGRF PGRPRGSGGG GGRGGRGNGA ERVRVALRRG
60 70 80 90 100
GGAAGPGGAE PGEDTALLRL LGLRRGLRRL RRLWAGARVQ RGRGRGRGRG
110 120 130 140 150
WGPNRGCMPE EESSDGESEE EEFQGFHSDE DVAPSSLRSA LRSQRGRAPR
160 170 180 190 200
GRGRKHKTTP LPPRLADVTP VPPKAPTRKR GEEGTERMVQ ALTELLRRSQ
210 220 230 240 250
APQPPRSRAR AREPSTPRRS RGRPPGRPAG PCRKKQQAVV LAEAAVTIPK
260 270 280 290 300
PEPPPPVVPV KNKAGSWKCK EGPGPGPGTP KRGGQPGRGG RGGRGRGRGG
310 320 330 340 350
LPLMIKFVSK AKKVKMGQLS QELESGQGHG QRGESWQDAP QRKDGDEPER
360 370 380 390 400
GSCRKKQEQK LEEEEEEEEK EGEEKEEKDD NEDNNKQEEE EETERAVAEE
410 420 430 440 450
EAMLAKEKEE AKLPSPPLTP PVPSPPPPLP PPSTSPPPPA SPLPPPVSPP
460 470 480 490 500
PPLSPPPYPA PEKQEESPPL VPATCSRKRG RPPLTPSQRA EREAARSGPE
510 520 530 540 550
GTLSPTPNPS TTTGSPLEDS PTVVPKSTTF LKNIRQFIMP VVSARSSRVI
560 570 580 590 600
KTPRRFMDED PPKPPKVEAS IVRPPVATSP PAPQEPVPVS SPPRVPTPPS
610 620 630 640 650
TPVPLPEKRR SILREPTFRW TSLTRELPPP PPAPPPAPSP PPAPATPSRR
660 670 680 690 700
PLLLRAPQFT PSEAHLKIYE SVLTPPPLGA LETPEPELPP ADDSPAEPEP
710 720 730 740 750
RAVGRTNHLS LPRFVPVVTS PVKVEVPPHG APALSEGQQL QLQQPPQALQ
760 770 780 790 800
TQLLPQALPP QQPQAQPPPS PQHTPPLEKA RVASLGSLPL SGVEEKMFSL
810 820 830 840 850
LKRAKVQLFK IDQQQQQKVA ASMPLSPAVQ TEEAVGTVKQ TPDRGCVRSE
860 870 880 890 900
DESMEAKRDR ASGPESPLQG PRIKHVCRHA AVALGQARAM VPEDVPRLSA
910 920 930 940 950
LPLRDRQDLA TEDTSSASET ESVPSRSQRE KVESAGPGGD SEPTGSTGAL
960 970 980 990 1000
AHTPRRSLPS HHGKKMRMAR CGHCRGCLRV QDCGSCVNCL DKPKFGGPNT
1010 1020 1030 1040 1050
KKQCCVYRKC DKIEARKMER LAKKGRTIVK TLLPWDSDES PEASPGPPGP
1060 1070 1080 1090 1100
RRGAGAGGSR EEVGATPGPE EQDSLLLQRK SARRCVKQRP SYDVFEDSDD
1110 1120 1130 1140 1150
SEPGGPPAPR RRTPREHELP VLEPEEQSRP RKPTLQPVLQ LKARRRLDKD
1160 1170 1180 1190 1200
ALAPGPFASF PNGWTGKQKS PDGVHRVRVD FKEDCDLENV WLMGGLSVLT
1210 1220 1230 1240 1250
SVPGGPPMVC LLCASKGLHE LVFCQVCCDP FHPFCLEEAE RPSPQHRDTW
1260 1270 1280 1290 1300
CCRRCKFCHV CGRKGRGSKH LLECERCRHA YHPACLGPSY PTRATRRRRH
1310 1320 1330 1340 1350
WICSACVRCK SCGATPGKNW DVEWSGDYSL CPRCTELYEK GNYCPICTRC
1360 1370 1380 1390 1400
YEDNDYESKM MQCAQCDHWV HAKCEGLSDE DYEILSGLPD SVLYTCGPCA
1410 1420 1430 1440 1450
GATQPRWREA LSGALQGGLR QVLQGLLSSK VAGPLLLCTQ CGQDGKQLHP
1460 1470 1480 1490 1500
GPCDLQAVGK RFEEGLYKSV HSFMEDVVAI LMRHSEEGET PERRAGSQMK
1510 1520 1530 1540 1550
GLLLKLLESA FCWFDAHDPK YWRRSTRLPN GVLPNAVLPP SLDHVYAQWR
1560 1570 1580 1590 1600
QQESETPESG QPPGDPSAAF QSKDPAAFSH LDDPRQCALC LKYGDADSKE
1610 1620 1630 1640 1650
AGRLLYIGQN EWTHVNCAIW SAEVFEENDG SLKNVHAAVA RGRQMRCELC
1660 1670 1680 1690 1700
LKPGATVGCC LSSCLSNFHF MCARASYCIF QDDKKVFCQK HTDLLDGKEI
1710 1720 1730 1740 1750
VTPDGFDVLR RVYVDFEGIN FKRKFLTGLE PDVINVLIGS IRINSLGTLS
1760 1770 1780 1790 1800
DLSDCEGRLF PIGYQCSRLY WSTVDARRRC WYRCRILEYR PWGPREEPVH
1810 1820 1830 1840 1850
LEAAEENQTI VHSPTPSSDT DSLIPGDPVH HSPIQNLDPP LRTDSSNGPP
1860 1870 1880 1890 1900
PTPRSFSGAR IKVPNYSPSR RPLGGVSFGP LPSPGSPSSL THHIPTVGDS
1910 1920 1930 1940 1950
DFPAPPRRSR RPSPLATRPP PSRRTSSPLR TSPQLRVPLS TSVTALTPTS
1960 1970 1980 1990 2000
GELAPPDLAP SPLPPSEDLG PDFEDMEVVS GLSAADLDFA ASLLGTEPFQ
2010 2020 2030 2040 2050
EEIVAAGAVG SSQGGPGDSS EEEASPTTHY VHFPVTVVSG PALAPSSLAG
2060 2070 2080 2090 2100
APRIEQLDGV DDGTDSEAEA VQQPRGQGTP PSGPGVGRGG VLGAAGDRAQ
2110 2120 2130 2140 2150
PPEDLPSEIV DFVLKNLGGP GEGAAGPRED SLPSAPPLAN GSQPPQSLST
2160 2170 2180 2190 2200
SPADPTRTFA WLPGAPGVRV LSLGPAPEPP KPATSKIILV NKLGQVFVKM
2210 2220 2230 2240 2250
AGEGEPVAPP VKQPPLPPII PPTAPTSWTL PPGPLLSVLP VVGVGVVRPA
2260 2270 2280 2290 2300
PPPPPPPLTL VFSSGPPSPP RQAIRVKRVS TFSGRSPPVP PPNKTPRLDE
2310 2320 2330 2340 2350
DGESLEDAHH VPGISGSGFS RVRMKTPTVR GVLDLNNPGE QPEEESPGRP
2360 2370 2380 2390 2400
QDRCPLLPLA EAPSQALDGS SDLLFESQWH HYSAGEASSS EEEPPSPEDK
2410 2420 2430 2440 2450
ENQVPKRVGP HLRFEISSDD GFSVEAESLE VAWRTLIEKV QEARGHARLR
2460 2470 2480 2490 2500
HLSFSGMSGA RLLGIHHDAV IFLAEQLPGA QRCQHYKFRY HQQGEGQEEP
2510 2520 2530 2540 2550
PLNPHGAARA EVYLRKCTFD MFNFLASQHR VLPEGATCDE EEDEVQLRST
2560 2570 2580 2590 2600
RRATSLELPM AMRFRHLKKT SKEAVGVYRS AIHGRGLFCK RNIDAGEMVI
2610 2620 2630 2640 2650
EYSGIVIRSV LTDKREKFYD GKGIGCYMFR MDDFDVVDAT MHGNAARFIN
2660 2670 2680 2690 2700
HSCEPNCFSR VIHVEGQKHI VIFALRRILR GEELTYDYKF PIEDASNKLP
2710
CNCGAKRCRR FLN
Length:2,713
Mass (Da):294,821
Last modified:July 27, 2011 - v3
Checksum:i2AD4343C5C081933
GO

Computationally mapped potential isoform sequencesi

There are 2 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
F8WJ40F8WJ40_MOUSE
Histone-lysine N-methyltransferase
Kmt2b Wbp7
2,721Annotation score:
F6W623F6W623_MOUSE
Histone-lysine N-methyltransferase ...
Kmt2b Wbp7
2,014Annotation score:

Sequence cautioni

The sequence AAC53192 differs from that shown. Possible contaminating sequence. The N-terminal 3 residues and C-terminal 8 residues do not match the underlying genomic sequence.Curated

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Sequence conflicti18G → V in BAD81031 (Ref. 1) Curated1
Sequence conflicti25 – 27RGS → LGC in BAD81031 (Ref. 1) Curated3

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AB182318 mRNA Translation: BAD81031.1
AC167970 Genomic DNA No translation available.
U92455 mRNA Translation: AAC53192.1 Sequence problems.
CCDSiCCDS21101.1
RefSeqiNP_083550.2, NM_029274.2
UniGeneiMm.168688

Genome annotation databases

EnsembliENSMUST00000108154; ENSMUSP00000103789; ENSMUSG00000006307
GeneIDi75410
KEGGimmu:75410
UCSCiuc009gfg.1 mouse

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AB182318 mRNA Translation: BAD81031.1
AC167970 Genomic DNA No translation available.
U92455 mRNA Translation: AAC53192.1 Sequence problems.
CCDSiCCDS21101.1
RefSeqiNP_083550.2, NM_029274.2
UniGeneiMm.168688

3D structure databases

ProteinModelPortaliO08550
SMRiO08550
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi217461, 3 interactors
CORUMiO08550
IntActiO08550, 1 interactor
MINTiO08550
STRINGi10090.ENSMUSP00000103789

PTM databases

iPTMnetiO08550
PhosphoSitePlusiO08550

Proteomic databases

EPDiO08550
MaxQBiO08550
PaxDbiO08550
PRIDEiO08550

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSMUST00000108154; ENSMUSP00000103789; ENSMUSG00000006307
GeneIDi75410
KEGGimmu:75410
UCSCiuc009gfg.1 mouse

Organism-specific databases

CTDi9757
MGIiMGI:109565 Kmt2b

Phylogenomic databases

eggNOGiKOG1084 Eukaryota
COG2940 LUCA
GeneTreeiENSGT00760000119228
HOGENOMiHOG000015326
HOVERGENiHBG100043
InParanoidiO08550
KOiK14959
TreeFamiTF319820

Enzyme and pathway databases

ReactomeiR-MMU-3214841 PKMTs methylate histone lysines
R-MMU-8936459 RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function

Miscellaneous databases

PROiPR:O08550
SOURCEiSearch...

Gene expression databases

BgeeiENSMUSG00000006307 Expressed in 245 organ(s), highest expression level in secondary oocyte
CleanExiMM_WBP7
ExpressionAtlasiO08550 baseline and differential
GenevisibleiO08550 MM

Family and domain databases

Gene3Di1.20.920.10, 1 hit
3.30.40.10, 3 hits
InterProiView protein in InterPro
IPR036427 Bromodomain-like_sf
IPR034732 EPHD
IPR003889 FYrich_C
IPR003888 FYrich_N
IPR016569 MeTrfase_trithorax
IPR003616 Post-SET_dom
IPR001214 SET_dom
IPR002857 Znf_CXXC
IPR011011 Znf_FYVE_PHD
IPR001965 Znf_PHD
IPR019787 Znf_PHD-finger
IPR013083 Znf_RING/FYVE/PHD
PfamiView protein in Pfam
PF05965 FYRC, 1 hit
PF05964 FYRN, 1 hit
PF00628 PHD, 2 hits
PF00856 SET, 1 hit
PF02008 zf-CXXC, 1 hit
PIRSFiPIRSF010354 Methyltransferase_trithorax, 1 hit
SMARTiView protein in SMART
SM00542 FYRC, 1 hit
SM00541 FYRN, 1 hit
SM00249 PHD, 4 hits
SM00508 PostSET, 1 hit
SM00317 SET, 1 hit
SUPFAMiSSF57903 SSF57903, 2 hits
PROSITEiView protein in PROSITE
PS51805 EPHD, 1 hit
PS51543 FYRC, 1 hit
PS51542 FYRN, 1 hit
PS50868 POST_SET, 1 hit
PS50280 SET, 1 hit
PS51058 ZF_CXXC, 1 hit
PS01359 ZF_PHD_1, 3 hits
PS50016 ZF_PHD_2, 3 hits
ProtoNetiSearch...

Entry informationi

Entry nameiKMT2B_MOUSE
AccessioniPrimary (citable) accession number: O08550
Secondary accession number(s): E9QKF4, Q5NU09
Entry historyiIntegrated into UniProtKB/Swiss-Prot: December 1, 2000
Last sequence update: July 27, 2011
Last modified: November 7, 2018
This is version 148 of the entry and version 3 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
  2. MGD cross-references
    Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
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