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Entry version 151 (07 Apr 2021)
Sequence version 1 (01 Jul 1997)
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Protein
Submitted name:

RNA polymerase factor sigma-54

Gene

rpoN

Organism
Listeria monocytogenes
Status
Unreviewed-Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Protein inferred from homologyi <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionDNA-bindingARBA annotation, NucleotidyltransferaseARBA annotation, Sigma factorARBA annotation, Transferase
Biological processTranscription, Transcription regulation

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Submitted name:
RNA polymerase factor sigma-54Imported
Submitted name:
RNA polymerase sigma factor sigma 54Imported
Submitted name:
RNA polymerase sigma-54 factor RpoNImported
Submitted name:
Sigma-54 proteinImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:rpoNImported
ORF Names:AFY08_10690Imported, AFY14_11815Imported, AOA09_13475Imported, B1N38_12635Imported, B1N39_11555Imported, B1N40_06195Imported, B1O10_09775Imported, B1O25_07000Imported, B4X79_11460Imported, B4X80_11985Imported, B4X87_12335Imported, B4X92_10605Imported, B4Y36_12215Imported, B4Y40_10965Imported, B4Y47_08330Imported, B4Y57_12215Imported, B5H26_12045Imported, CCZ59_13680Imported, D3B94_13615Imported, EDI43_04385Imported, FORC68_2461Imported, FR217_12830Imported, FVI78_11790Imported, GJW26_13460Imported, HRK22_01385Imported, TX60_07875Imported, ZY91_13780Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiListeria monocytogenesImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri1639 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiBacteriaFirmicutesBacilliBacillalesListeriaceaeListeria
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000327645 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Unassembled WGS sequence
  • UP000412663 Componenti: Unassembled WGS sequence
  • UP000400212 Componenti: Unassembled WGS sequence
  • UP000401494 Componenti: Unassembled WGS sequence
  • UP000379716 Componenti: Unassembled WGS sequence
  • UP000295446 Componenti: Chromosome
  • UP000406015 Componenti: Unassembled WGS sequence
  • UP000393672 Componenti: Unassembled WGS sequence
  • UP000283665 Componenti: Unassembled WGS sequence
  • UP000480909 Componenti: Unassembled WGS sequence
  • UP000327754 Componenti: Unassembled WGS sequence
  • UP000410674 Componenti: Unassembled WGS sequence
  • UP000352536 Componenti: Unassembled WGS sequence
  • UP000502106 Componenti: Chromosome
  • UP000349296 Componenti: Unassembled WGS sequence
  • UP000383652 Componenti: Unassembled WGS sequence
  • UP000330940 Componenti: Unassembled WGS sequence
  • UP000455458 Componenti: Unassembled WGS sequence
  • UP000398027 Componenti: Unassembled WGS sequence
  • UP000411086 Componenti: Unassembled WGS sequence
  • UP000270746 Componenti: Unassembled WGS sequence
  • UP000370839 Componenti: Unassembled WGS sequence
  • UP000372189 Componenti: Unassembled WGS sequence
  • UP000360871 Componenti: Unassembled WGS sequence
  • UP000413484 Componenti: Unassembled WGS sequence
  • UP000328841 Componenti: Unassembled WGS sequence
  • UP000385787 Componenti: Unassembled WGS sequence

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Keywords - Cellular componenti

DNA-directed RNA polymeraseARBA annotation

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family%5Fand%5Fdomains%5Fsection">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini83 – 269Sigma54_CBDInterPro annotationAdd BLAST187
Domaini283 – 446Sigma54_DBDInterPro annotationAdd BLAST164

<p>This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the sigma-54 factor family.ARBA annotation

Family and domain databases

Conserved Domains Database

More...
CDDi
cd01392, HTH_LacI, 1 hit

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
1.10.10.1330, 1 hit
1.10.260.40, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR000843, HTH_LacI
IPR010982, Lambda_DNA-bd_dom_sf
IPR000394, RNA_pol_sigma_54
IPR007046, RNA_pol_sigma_54_core-bd
IPR007634, RNA_pol_sigma_54_DNA-bd
IPR038709, RpoN_core-bd_sf

The PANTHER Classification System

More...
PANTHERi
PTHR32248, PTHR32248, 1 hit

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF00309, Sigma54_AID, 1 hit
PF04963, Sigma54_CBD, 1 hit
PF04552, Sigma54_DBD, 1 hit

PIRSF; a whole-protein classification database

More...
PIRSFi
PIRSF000774, RpoN, 1 hit

Protein Motif fingerprint database; a protein domain database

More...
PRINTSi
PR00045, SIGMA54FCT

TIGRFAMs; a protein family database

More...
TIGRFAMsi
TIGR02395, rpoN_sigma, 1 hit

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS00717, SIGMA54_1, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

O08352-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MRLESNFVQK QQQKQSQKLN MTQQLSQSIA MLQFATADLV AFLEDKALEN
60 70 80 90 100
PLIEVIPGSD FATDFSYSSR KSAGSSDDTD WLEQIADNKM TLADALKEQL
110 120 130 140 150
HLMDVTQTQK IIVLYLIESL NDNGYLQIDL KDVSAALLMD DSSVLEGLEI
160 170 180 190 200
LQSMEPAGVG ARDARECILL QIERSPDAPY IAYDVIQKFF TEFAEKKWKK
210 220 230 240 250
IASEMDVSLQ DIQEVSDYIQ TLNPKPGSEF ESERVQYVVP DLILLQHEDE
260 270 280 290 300
FAVSLAKQFL PQVRFQEAYY ETMRATEEKD VAQFLREKAG EFDWIKKGIE
310 320 330 340 350
QRESTLQRVG EAIVSHQKAY FLDNSAHLQP LTLKEVAEEL GVHESTVSRA
360 370 380 390 400
VNGKYMETTN GVYELKRFFA SGLQKKSSEN ENIGDISSTT IKKLVQEFVA
410 420 430 440
AEDKLKPLSD QKIVDMLAEK EIQVSRRAIA KYRLELNIPS SSKRKRF
Length:447
Mass (Da):50,855
Last modified:July 1, 1997 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iE92BACAF422B3472
GO

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

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GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
KF540169 Genomic DNA Translation: AHA85012.1
KF540170 Genomic DNA Translation: AHA85013.1
KF540171 Genomic DNA Translation: AHA85014.1
KF540172 Genomic DNA Translation: AHA85015.1
KF540173 Genomic DNA Translation: AHA85016.1
KF540174 Genomic DNA Translation: AHA85017.1
KF540176 Genomic DNA Translation: AHA85019.1
KF540196 Genomic DNA Translation: AHA85039.1
KF540197 Genomic DNA Translation: AHA85040.1
KF540198 Genomic DNA Translation: AHA85041.1
KF540199 Genomic DNA Translation: AHA85042.1
KF540200 Genomic DNA Translation: AHA85043.1
KF540201 Genomic DNA Translation: AHA85044.1
KF540202 Genomic DNA Translation: AHA85045.1
KF540203 Genomic DNA Translation: AHA85046.1
KF540205 Genomic DNA Translation: AHA85048.1
KF540206 Genomic DNA Translation: AHA85049.1
KF540210 Genomic DNA Translation: AHA85053.1
X93169 Genomic DNA Translation: CAA63657.1
AAAAEK010000006 Genomic DNA Translation: EAA0288855.1
AAAHXY010000006 Genomic DNA Translation: EAC3544726.1
AAAIBW010000006 Genomic DNA Translation: EAC3853958.1
AAAIKJ010000006 Genomic DNA Translation: EAC4520505.1
AAAIVC010000005 Genomic DNA Translation: EAC5357726.1
AAAIVQ010000005 Genomic DNA Translation: EAC5406232.1
AAAIWH010000005 Genomic DNA Translation: EAC5459032.1
AAAJWK010000007 Genomic DNA Translation: EAC7541547.1
AAAKTJ010000007 Genomic DNA Translation: EAC9289849.1
AAAKUA010000005 Genomic DNA Translation: EAC9344124.1
AAAKVI010000005 Genomic DNA Translation: EAC9447287.1
AAAKVN010000004 Genomic DNA Translation: EAC9463913.1
AAAKVM010000012 Genomic DNA Translation: EAC9466774.1
AAAKWG010000005 Genomic DNA Translation: EAC9530902.1
AAAKWO010000005 Genomic DNA Translation: EAC9549333.1
AAALIQ010000005 Genomic DNA Translation: EAD0496708.1
AAAMEQ010000005 Genomic DNA Translation: EAD2192901.1
AAAMTO010000006 Genomic DNA Translation: EAD3359194.1
AAAPOT010000005 Genomic DNA Translation: EAD9094987.1
AABAZG010000005 Genomic DNA Translation: EAG2302542.1
AAJDON010000007 Genomic DNA Translation: ECK8153298.1
AANDRZ010000012 Genomic DNA Translation: EDN9793045.1
AANEGM010000006 Genomic DNA Translation: EDO0909157.1
RSVN01000004 Genomic DNA Translation: MIV57273.1
CP029175 Genomic DNA Translation: QBZ19689.1
CP054042 Genomic DNA Translation: QKI98616.1
QYFE01000006 Genomic DNA Translation: RJB31005.1

Protein sequence database of the Protein Information Resource

More...
PIRi
AE1382

NCBI Reference Sequences

More...
RefSeqi
WP_003732487.1, NZ_WUEC01000004.1

Genome annotation databases

Ensembl bacterial and archaeal genome annotation project

More...
EnsemblBacteriai
QBZ19689; QBZ19689; FORC68_2461

Pathosystems Resource Integration Center (PATRIC)

More...
PATRICi
fig|1639.1007.peg.2476

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
KF540169 Genomic DNA Translation: AHA85012.1
KF540170 Genomic DNA Translation: AHA85013.1
KF540171 Genomic DNA Translation: AHA85014.1
KF540172 Genomic DNA Translation: AHA85015.1
KF540173 Genomic DNA Translation: AHA85016.1
KF540174 Genomic DNA Translation: AHA85017.1
KF540176 Genomic DNA Translation: AHA85019.1
KF540196 Genomic DNA Translation: AHA85039.1
KF540197 Genomic DNA Translation: AHA85040.1
KF540198 Genomic DNA Translation: AHA85041.1
KF540199 Genomic DNA Translation: AHA85042.1
KF540200 Genomic DNA Translation: AHA85043.1
KF540201 Genomic DNA Translation: AHA85044.1
KF540202 Genomic DNA Translation: AHA85045.1
KF540203 Genomic DNA Translation: AHA85046.1
KF540205 Genomic DNA Translation: AHA85048.1
KF540206 Genomic DNA Translation: AHA85049.1
KF540210 Genomic DNA Translation: AHA85053.1
X93169 Genomic DNA Translation: CAA63657.1
AAAAEK010000006 Genomic DNA Translation: EAA0288855.1
AAAHXY010000006 Genomic DNA Translation: EAC3544726.1
AAAIBW010000006 Genomic DNA Translation: EAC3853958.1
AAAIKJ010000006 Genomic DNA Translation: EAC4520505.1
AAAIVC010000005 Genomic DNA Translation: EAC5357726.1
AAAIVQ010000005 Genomic DNA Translation: EAC5406232.1
AAAIWH010000005 Genomic DNA Translation: EAC5459032.1
AAAJWK010000007 Genomic DNA Translation: EAC7541547.1
AAAKTJ010000007 Genomic DNA Translation: EAC9289849.1
AAAKUA010000005 Genomic DNA Translation: EAC9344124.1
AAAKVI010000005 Genomic DNA Translation: EAC9447287.1
AAAKVN010000004 Genomic DNA Translation: EAC9463913.1
AAAKVM010000012 Genomic DNA Translation: EAC9466774.1
AAAKWG010000005 Genomic DNA Translation: EAC9530902.1
AAAKWO010000005 Genomic DNA Translation: EAC9549333.1
AAALIQ010000005 Genomic DNA Translation: EAD0496708.1
AAAMEQ010000005 Genomic DNA Translation: EAD2192901.1
AAAMTO010000006 Genomic DNA Translation: EAD3359194.1
AAAPOT010000005 Genomic DNA Translation: EAD9094987.1
AABAZG010000005 Genomic DNA Translation: EAG2302542.1
AAJDON010000007 Genomic DNA Translation: ECK8153298.1
AANDRZ010000012 Genomic DNA Translation: EDN9793045.1
AANEGM010000006 Genomic DNA Translation: EDO0909157.1
RSVN01000004 Genomic DNA Translation: MIV57273.1
CP029175 Genomic DNA Translation: QBZ19689.1
CP054042 Genomic DNA Translation: QKI98616.1
QYFE01000006 Genomic DNA Translation: RJB31005.1
PIRiAE1382
RefSeqiWP_003732487.1, NZ_WUEC01000004.1

3D structure databases

Database of comparative protein structure models

More...
ModBasei
Search...

SWISS-MODEL Interactive Workspace

More...
SWISS-MODEL-Workspacei
Submit a new modelling project...

Genome annotation databases

EnsemblBacteriaiQBZ19689; QBZ19689; FORC68_2461
PATRICifig|1639.1007.peg.2476

Family and domain databases

CDDicd01392, HTH_LacI, 1 hit
Gene3Di1.10.10.1330, 1 hit
1.10.260.40, 1 hit
InterProiView protein in InterPro
IPR000843, HTH_LacI
IPR010982, Lambda_DNA-bd_dom_sf
IPR000394, RNA_pol_sigma_54
IPR007046, RNA_pol_sigma_54_core-bd
IPR007634, RNA_pol_sigma_54_DNA-bd
IPR038709, RpoN_core-bd_sf
PANTHERiPTHR32248, PTHR32248, 1 hit
PfamiView protein in Pfam
PF00309, Sigma54_AID, 1 hit
PF04963, Sigma54_CBD, 1 hit
PF04552, Sigma54_DBD, 1 hit
PIRSFiPIRSF000774, RpoN, 1 hit
PRINTSiPR00045, SIGMA54FCT
TIGRFAMsiTIGR02395, rpoN_sigma, 1 hit
PROSITEiView protein in PROSITE
PS00717, SIGMA54_1, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiO08352_LISMN
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: O08352
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: July 1, 1997
Last sequence update: July 1, 1997
Last modified: April 7, 2021
This is version 151 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)
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