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UniProtKB - O07002 (ASPP_BACSU)
Protein
Aspartate-proton symporter
Gene
yveA
Organism
Bacillus subtilis (strain 168)
Status
Functioni
Uptake of L-aspartate with the concomitant import of a proton. Can also transport aspartate hydroxamate and L-glutamate with lower affinity and efficiency.
Miscellaneous
Allows enhanced growth with L-aspartate as a sole source nitrogen source.
Inhibited by carbonyl cyanide m-chlorophenylhydrazone and carbonyl cyanide 4-trifluoro-methoxyphenylhydrazone.
GO - Molecular functioni
- symporter activity Source: UniProtKB-KW
GO - Biological processi
- amino acid transport Source: UniProtKB-KW
Keywordsi
Biological process | Amino-acid transport, Symport, Transport |
Enzyme and pathway databases
BioCyci | BSUB:BSU34470-MONOMER |
Protein family/group databases
TCDBi | 2.A.3.11.1, the amino acid-polyamine-organocation (apc) family |
Names & Taxonomyi
Protein namesi | Recommended name: Aspartate-proton symporterAlternative name(s): L-aspartate transporter |
Gene namesi | Name:yveA Ordered Locus Names:BSU34470 |
Organismi | Bacillus subtilis (strain 168) |
Taxonomic identifieri | 224308 [NCBI] |
Taxonomic lineagei | Bacteria › Firmicutes › Bacilli › Bacillales › Bacillaceae › Bacillus › |
Proteomesi |
|
Subcellular locationi
Plasma membrane
Plasma Membrane
- plasma membrane Source: UniProtKB-SubCell
Other locations
- integral component of membrane Source: UniProtKB-KW
Topology
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Transmembranei | 13 – 33 | HelicalSequence analysisAdd BLAST | 21 | |
Transmembranei | 49 – 69 | HelicalSequence analysisAdd BLAST | 21 | |
Transmembranei | 85 – 105 | HelicalSequence analysisAdd BLAST | 21 | |
Transmembranei | 130 – 150 | HelicalSequence analysisAdd BLAST | 21 | |
Transmembranei | 161 – 181 | HelicalSequence analysisAdd BLAST | 21 | |
Transmembranei | 201 – 221 | HelicalSequence analysisAdd BLAST | 21 | |
Transmembranei | 232 – 252 | HelicalSequence analysisAdd BLAST | 21 | |
Transmembranei | 281 – 301 | HelicalSequence analysisAdd BLAST | 21 | |
Transmembranei | 345 – 365 | HelicalSequence analysisAdd BLAST | 21 | |
Transmembranei | 366 – 386 | HelicalSequence analysisAdd BLAST | 21 | |
Transmembranei | 402 – 422 | HelicalSequence analysisAdd BLAST | 21 | |
Transmembranei | 425 – 445 | HelicalSequence analysisAdd BLAST | 21 | |
Transmembranei | 460 – 480 | HelicalSequence analysisAdd BLAST | 21 | |
Transmembranei | 482 – 502 | HelicalSequence analysisAdd BLAST | 21 |
Keywords - Cellular componenti
Cell membrane, MembranePTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
ChainiPRO_0000054283 | 1 – 520 | Aspartate-proton symporterAdd BLAST | 520 |
Proteomic databases
PaxDbi | O07002 |
Expressioni
Inductioni
Induced by sucrose.1 Publication
Family & Domainsi
Sequence similaritiesi
Belongs to the amino acid-polyamine-organocation (APC) superfamily. AGT (TC 2.A.3.11) family. [View classification]Curated
Keywords - Domaini
Transmembrane, Transmembrane helixPhylogenomic databases
eggNOGi | COG0531, Bacteria |
InParanoidi | O07002 |
OMAi | FRGWGSL |
PhylomeDBi | O07002 |
Family and domain databases
InterProi | View protein in InterPro IPR002293, AA/rel_permease1 |
Pfami | View protein in Pfam PF13520, AA_permease_2, 1 hit |
i Sequence
Sequence statusi: Complete.
O07002-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MSKQGNFQKS MSLFDLILIG MGAIFGSAWL FAVSNVASKA GPSGAFSWIL
60 70 80 90 100
GGAIILLIGL VYAELGAALP RTGGIIRYPV YSHGHLVGYL ISFVTIVAYT
110 120 130 140 150
SLISIEVTAV RQYVAYWFPG LTIKGSDSPT ISGWILQFAL LCLFFLLNYW
160 170 180 190 200
SVKTFAKANF IISIFKYIVP ITIIIVLIFH FQPENLSVQG FAPFGFTGIQ
210 220 230 240 250
AAISTGGVMF AYLGLHPIVS VAGEVQNPKR NIPIALIICI IVSTIIYTVL
260 270 280 290 300
QVTFIGAIPT ETLKHGWPAI GREFSLPFKD IAVMLGLGWL ATLVILDAIL
310 320 330 340 350
SPGGNGNIFM NTTSRLVYAW ARNGTLFGIF SKVNKDTGTP RASLWLSFAL
360 370 380 390 400
SIFWTLPFPS WNALVNVCSV ALILSYAIAP ISSAALRVNA KDLNRPFYLK
410 420 430 440 450
GMSIIGPLSF IFTAFIVYWS GWKTVSWLLG SQLVMFLIYL CFSKYTPKED
460 470 480 490 500
VSLAQQLKSA WWLIGFYIMM LIFSYIGSFG HGLGIISNPV DLILVAIGSL
510 520
AIYYWAKYTG LPKAAIDYDK
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | Z94043 Genomic DNA Translation: CAB08050.1 AL009126 Genomic DNA Translation: CAB15452.1 |
PIRi | D70035 |
RefSeqi | NP_391327.1, NC_000964.3 WP_003228228.1, NZ_JNCM01000033.1 |
Genome annotation databases
EnsemblBacteriai | CAB15452; CAB15452; BSU_34470 |
GeneIDi | 938612 |
KEGGi | bsu:BSU34470 |
PATRICi | fig|224308.179.peg.3734 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | Z94043 Genomic DNA Translation: CAB08050.1 AL009126 Genomic DNA Translation: CAB15452.1 |
PIRi | D70035 |
RefSeqi | NP_391327.1, NC_000964.3 WP_003228228.1, NZ_JNCM01000033.1 |
3D structure databases
SMRi | O07002 |
ModBasei | Search... |
Protein-protein interaction databases
STRINGi | 224308.BSU34470 |
Protein family/group databases
TCDBi | 2.A.3.11.1, the amino acid-polyamine-organocation (apc) family |
Proteomic databases
PaxDbi | O07002 |
Genome annotation databases
EnsemblBacteriai | CAB15452; CAB15452; BSU_34470 |
GeneIDi | 938612 |
KEGGi | bsu:BSU34470 |
PATRICi | fig|224308.179.peg.3734 |
Phylogenomic databases
eggNOGi | COG0531, Bacteria |
InParanoidi | O07002 |
OMAi | FRGWGSL |
PhylomeDBi | O07002 |
Enzyme and pathway databases
BioCyci | BSUB:BSU34470-MONOMER |
Family and domain databases
InterProi | View protein in InterPro IPR002293, AA/rel_permease1 |
Pfami | View protein in Pfam PF13520, AA_permease_2, 1 hit |
MobiDBi | Search... |
Entry informationi
Entry namei | ASPP_BACSU | |
Accessioni | O07002Primary (citable) accession number: O07002 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | March 1, 2004 |
Last sequence update: | July 1, 1997 | |
Last modified: | February 23, 2022 | |
This is version 122 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Prokaryotic Protein Annotation Program |
Miscellaneousi
Keywords - Technical termi
Reference proteomeDocuments
- SIMILARITY comments
Index of protein domains and families