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Entry version 113 (10 Apr 2019)
Sequence version 1 (01 Jul 1997)
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Protein

Maltose phosphorylase

Gene

mdxK

Organism
Bacillus subtilis (strain 168)
Status
Reviewed-Annotation score:

Annotation score:3 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Protein inferred from homologyi <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Catalyzes the phosphorolysis of maltose, leading to the formation of glucose and glucose 1-P.By similarity

<p>This subsection of the <a href="http://www.uniprot.org/help/function_section">Function</a> section describes the catalytic activity of an enzyme, i.e. a chemical reaction that the enzyme catalyzes.<p><a href='/help/catalytic_activity' target='_top'>More...</a></p>Catalytic activityi

<p>This subsection of the <a href="http://www.uniprot.org/help/function_section">'Function'</a> section describes the metabolic pathway(s) associated with a protein.<p><a href='/help/pathway' target='_top'>More...</a></p>Pathwayi: maltose degradation

This protein is involved in the pathway maltose degradation, which is part of Glycan degradation.
View all proteins of this organism that are known to be involved in the pathway maltose degradation and in Glycan degradation.

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Function’ section is used for enzymes and indicates the residues directly involved in catalysis.<p><a href='/help/act_site' target='_top'>More...</a></p>Active sitei483Proton donorBy similarity1

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionGlycosyltransferase, Transferase
Biological processCarbohydrate metabolism

Enzyme and pathway databases

BioCyc Collection of Pathway/Genome Databases

More...
BioCyci
BSUB:BSU34570-MONOMER

UniPathway: a resource for the exploration and annotation of metabolic pathways

More...
UniPathwayi
UPA00150

Protein family/group databases

Carbohydrate-Active enZymes

More...
CAZyi
GH65 Glycoside Hydrolase Family 65

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Maltose phosphorylase (EC:2.4.1.8)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:mdxK
Synonyms:malK, yvdK
Ordered Locus Names:BSU34570
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiBacillus subtilis (strain 168)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri224308 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiBacteriaFirmicutesBacilliBacillalesBacillaceaeBacillus
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000001570 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

GO - Cellular componenti

  • cell wall Source: GO_Central

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00001080181 – 757Maltose phosphorylaseAdd BLAST757

Proteomic databases

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
O06993

PRoteomics IDEntifications database

More...
PRIDEi
O06993

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

Protein interaction database and analysis system

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IntActi
O06993, 1 interactor

STRING: functional protein association networks

More...
STRINGi
224308.BSU34570

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

Protein Model Portal of the PSI-Nature Structural Biology Knowledgebase

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ProteinModelPortali
O06993

SWISS-MODEL Repository - a database of annotated 3D protein structure models

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SMRi
O06993

Database of comparative protein structure models

More...
ModBasei
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni354 – 355Substrate bindingBy similarity2
Regioni588 – 589Substrate bindingBy similarity2

<p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the glycosyl hydrolase 65 family.Curated

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
COG1554 LUCA

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
HOG000055023

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
O06993

KEGG Orthology (KO)

More...
KOi
K00691

Identification of Orthologs from Complete Genome Data

More...
OMAi
EAYCIPF

Database for complete collections of gene phylogenies

More...
PhylomeDBi
O06993

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
1.50.10.10, 1 hit
2.70.98.40, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR008928 6-hairpin_glycosidase_sf
IPR012341 6hp_glycosidase-like_sf
IPR011013 Gal_mutarotase_sf_dom
IPR005194 Glyco_hydro_65_C
IPR005195 Glyco_hydro_65_M
IPR005196 Glyco_hydro_65_N
IPR037018 Glyco_hydro_65_N_sf
IPR017045 Malt_Pase/Glycosyl_Hdrlase

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF03633 Glyco_hydro_65C, 1 hit
PF03632 Glyco_hydro_65m, 1 hit
PF03636 Glyco_hydro_65N, 1 hit

PIRSF; a whole-protein classification database

More...
PIRSFi
PIRSF036289 Glycosyl_hydrolase_malt_phosph, 1 hit

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF48208 SSF48208, 1 hit
SSF74650 SSF74650, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>.<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

O06993-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MINQRLFEID EWKIKTNTFN KEHTRLLESL TSLANGYMGV RGNFEEGYSG
60 70 80 90 100
DSHQGTYIAG VWFPDKTRVG WWKNGYPEYF GKVINAMNFM GIGLYVDGEK
110 120 130 140 150
IDLHQNPIEL FEVELNMKEG ILRRSAVVRI QDKTVRIRSE RFLSLAVKEL
160 170 180 190 200
CAIHYEAECL TGDAVITLVP YLDGNVANED SNYQEQFWQE EAKGADSHSG
210 220 230 240 250
HLAAKTIENP FGTPRFTVLA AMANETEGFV HESFKTTEMY VENRYSYQTK
260 270 280 290 300
ASLKKFVIVT TSRDFREEEL LSKAKELLAD VVENGYEDAK RRHTDRWKER
310 320 330 340 350
WAKADIEIKG DEELQQGIRY NIFQLFSTYY GGDARLNIGP KGFTGEKYGG
360 370 380 390 400
AAYWDTEAYA VPMYLATAEP EVTKNLLLYR YHQLEAAKRN AAKLGMKGAL
410 420 430 440 450
YPMVTFTGDE CHNEWEITFE EIHRNGAICY AIYNYINYTG DRNYMEEYGI
460 470 480 490 500
DVLVAVSRFW ADRVHFSKRK NKYMIHGVTG PNEYENNVNN NWYTNVIAAW
510 520 530 540 550
TLEYTLQSLE SISAEKRRHL DVQEVELEVW REIIQHMYYP FSEELQIFVQ
560 570 580 590 600
HDTFLDKDLQ TVDELDPAER PLYQNWSWDK ILRSNFIKQA DVLQGIYLFN
610 620 630 640 650
DRFTMEEKRR NFEFYEPMTV HESSLSPSVH AILAAELKLE KKALELYKRT
660 670 680 690 700
ARLDLDNYNH DTEEGLHITS MTGSWLAIVH GFAGMRTANE TLSFAPFLPK
710 720 730 740 750
EWDEYSFNIN YRNRLINVTV DEKRVIFELV KGEPLHMNVY EEPVVLQGRC

ERRTPNE
Length:757
Mass (Da):88,279
Last modified:July 1, 1997 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i75B3ECE933850F29
GO

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

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EMBLi

GenBank nucleotide sequence database

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GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
Z94043 Genomic DNA Translation: CAB08040.1
AL009126 Genomic DNA Translation: CAB15462.1

Protein sequence database of the Protein Information Resource

More...
PIRi
C70034

NCBI Reference Sequences

More...
RefSeqi
NP_391337.1, NC_000964.3
WP_003243769.1, NZ_JNCM01000033.1

Genome annotation databases

Ensembl bacterial and archaeal genome annotation project

More...
EnsemblBacteriai
CAB15462; CAB15462; BSU34570

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
938621

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
bsu:BSU34570

Pathosystems Resource Integration Center (PATRIC)

More...
PATRICi
fig|224308.179.peg.3744

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
Z94043 Genomic DNA Translation: CAB08040.1
AL009126 Genomic DNA Translation: CAB15462.1
PIRiC70034
RefSeqiNP_391337.1, NC_000964.3
WP_003243769.1, NZ_JNCM01000033.1

3D structure databases

ProteinModelPortaliO06993
SMRiO06993
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

IntActiO06993, 1 interactor
STRINGi224308.BSU34570

Protein family/group databases

CAZyiGH65 Glycoside Hydrolase Family 65

Proteomic databases

PaxDbiO06993
PRIDEiO06993

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiCAB15462; CAB15462; BSU34570
GeneIDi938621
KEGGibsu:BSU34570
PATRICifig|224308.179.peg.3744

Phylogenomic databases

eggNOGiCOG1554 LUCA
HOGENOMiHOG000055023
InParanoidiO06993
KOiK00691
OMAiEAYCIPF
PhylomeDBiO06993

Enzyme and pathway databases

UniPathwayi
UPA00150

BioCyciBSUB:BSU34570-MONOMER

Family and domain databases

Gene3Di1.50.10.10, 1 hit
2.70.98.40, 1 hit
InterProiView protein in InterPro
IPR008928 6-hairpin_glycosidase_sf
IPR012341 6hp_glycosidase-like_sf
IPR011013 Gal_mutarotase_sf_dom
IPR005194 Glyco_hydro_65_C
IPR005195 Glyco_hydro_65_M
IPR005196 Glyco_hydro_65_N
IPR037018 Glyco_hydro_65_N_sf
IPR017045 Malt_Pase/Glycosyl_Hdrlase
PfamiView protein in Pfam
PF03633 Glyco_hydro_65C, 1 hit
PF03632 Glyco_hydro_65m, 1 hit
PF03636 Glyco_hydro_65N, 1 hit
PIRSFiPIRSF036289 Glycosyl_hydrolase_malt_phosph, 1 hit
SUPFAMiSSF48208 SSF48208, 1 hit
SSF74650 SSF74650, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiMALPY_BACSU
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: O06993
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: July 15, 1998
Last sequence update: July 1, 1997
Last modified: April 10, 2019
This is version 113 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
  2. Glycosyl hydrolases
    Classification of glycosyl hydrolase families and list of entries
  3. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  4. Bacillus subtilis
    Bacillus subtilis (strain 168): entries, gene names and cross-references to SubtiList
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