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Entry version 56 (08 May 2019)
Sequence version 1 (01 Jul 1997)
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Protein
Submitted name:

Sb component

Gene

sbs

Organism
[Clostridium] spiroforme
Status
Unreviewed-Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Protein predictedi <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Biological processi

Protein family/group databases

Transport Classification Database

More...
TCDBi
1.C.42.1.7 the channel-forming bacillus anthracis protective antigen (bapa) family

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Submitted name:
Sb componentImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:sbsImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>Organismi[Clostridium] spiroformeImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri29348 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiBacteriaFirmicutesErysipelotrichiaErysipelotrichalesErysipelotrichaceaeErysipelatoclostridium

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

GO - Cellular componenti

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section denotes the presence of an N-terminal signal peptide.<p><a href='/help/signal' target='_top'>More...</a></p>Signal peptidei1 – 26Sequence analysisAdd BLAST26
<p>This subsection of the ‘PTM / Processing’ section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_500415771227 – 879Sequence analysisAdd BLAST853

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

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SMRi
O06498

Database of comparative protein structure models

More...
ModBasei
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family_and_domains_section">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini47 – 180PA14InterPro annotationAdd BLAST134

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Domaini

SignalSequence analysis

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
2.60.120.240, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR003896 Bacterial_exotoxin_B
IPR035331 Binary_toxB_3
IPR011658 PA14_dom
IPR035088 PA_Ca-bd
IPR027439 PA_heptamer_dom
IPR037149 PA_heptamer_dom_sf

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF03495 Binary_toxB, 1 hit
PF17475 Binary_toxB_2, 1 hit
PF17476 Binary_toxB_3, 1 hit

Protein Motif fingerprint database; a protein domain database

More...
PRINTSi
PR01391 BINARYTOXINB

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00758 PA14, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

O06498-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MKNKKILGLL TCTVLVGQMM TYPVYAKTIT QNYDNQEVET TNEKTVSSNG
60 70 80 90 100
LMGYYFADEH FKDLELMAPV KNGELKFEKN KVEKLLTEEK TNIKSIRWTG
110 120 130 140 150
RIIPSKDGEY TLSTDKDNVL MQINAEGEIA NTLKVNMIKG QEYSIRIEIQ
160 170 180 190 200
DKDIGYVDDL SSPKLYWELN GDKTLIPEKN LFLRDYSKID ENDPFIPKDN
210 220 230 240 250
FFDLKLKSRS ARLASGWGDE DLDTDNDNIP DAYEKNGYTI KDSIAVKWED
260 270 280 290 300
SFAQQGYKKY LSSYLESNTA GDPYTDYQKA SGSFDKAIKA EARDPLVAAY
310 320 330 340 350
PVVGVGMEKL IISTNEHAST DQGKTVSRNT TNSKTDANTA GVAINIAYQN
360 370 380 390 400
GFTGSITTNY SHTTENSTAV QNSNGESWNT SLSINKGESA YINANVRYYN
410 420 430 440 450
TGTAPMYKVT PTTNLVLDGD TLTTIKAQDN QIGNNLSPNE TYPKKGLSPL
460 470 480 490 500
ALNTMDQFSS RLIPINYDQL KKLDAGKQIK LETTQVSGNY GIKNSQGQII
510 520 530 540 550
TEGNSWSDYI SQIDSLSASI ILDTGSDVFE RRVTAKDSSN PEDKTPVLTI
560 570 580 590 600
GEAIEKAFGA TKNGEILYFN GMPIDESCVE LIFDGNTANL IKERLNALND
610 620 630 640 650
KKIYNVQLER GMKILIKTST YFNNFDGYNN FPSSWSNVDS NNQDGLQNAA
660 670 680 690 700
NKLSGETKIV IPMSKLNPYK RYVFSGYLKN SSTSNPITVN IKAKEQKTYN
710 720 730 740 750
LVSENDYKKF SYEFETIGRD ASNIEITLTS SGTIFLDNLS ITELNSTPEI
760 770 780 790 800
LKEPDIKVPS DQEIIDAHKK YYADLSFNQS TANYYLDGLY FEPTQTNKEV
810 820 830 840 850
LDYIQKYKVE ATLEYSGFKD IGTKDKELRN YTGDSNQPKT NYVNFRSYFT
860 870
SGENVMPYKK LRIYAITPEN KELLVLSIN
Length:879
Mass (Da):98,739
Last modified:July 1, 1997 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i40685ACB8E05BA01
GO

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
X97969 Genomic DNA Translation: CAA66612.1

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X97969 Genomic DNA Translation: CAA66612.1

3D structure databases

SMRiO06498
ModBaseiSearch...

Protein family/group databases

TCDBi1.C.42.1.7 the channel-forming bacillus anthracis protective antigen (bapa) family

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Family and domain databases

Gene3Di2.60.120.240, 1 hit
InterProiView protein in InterPro
IPR003896 Bacterial_exotoxin_B
IPR035331 Binary_toxB_3
IPR011658 PA14_dom
IPR035088 PA_Ca-bd
IPR027439 PA_heptamer_dom
IPR037149 PA_heptamer_dom_sf
PfamiView protein in Pfam
PF03495 Binary_toxB, 1 hit
PF17475 Binary_toxB_2, 1 hit
PF17476 Binary_toxB_3, 1 hit
PRINTSiPR01391 BINARYTOXINB
SMARTiView protein in SMART
SM00758 PA14, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiO06498_9FIRM
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: O06498
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: July 1, 1997
Last sequence update: July 1, 1997
Last modified: May 8, 2019
This is version 56 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)
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