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UniProtKB - O06486 (RFBF_BACSU)
Protein
Probable glucose-1-phosphate cytidylyltransferase
Gene
yfnH
Organism
Bacillus subtilis (strain 168)
Status
Functioni
Catalyzes the transfer of a CMP moiety from CTP to glucose 1-phosphate.
By similarityCatalytic activityi
- EC:2.7.7.33
Cofactori
Mg2+By similarityNote: Binds 1 Mg2+ ion per subunit.By similarity
Sites
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Binding sitei | 23 | SubstrateBy similarity | 1 | |
Binding sitei | 103 | Substrate; via carbonyl oxygenBy similarity | 1 | |
Binding sitei | 108 | SubstrateBy similarity | 1 | |
Binding sitei | 126 | Substrate; via amide nitrogenBy similarity | 1 | |
Metal bindingi | 127 | MagnesiumBy similarity | 1 | |
Metal bindingi | 232 | MagnesiumBy similarity | 1 |
GO - Molecular functioni
- glucose-1-phosphate cytidylyltransferase activity Source: UniProtKB-EC
- metal ion binding Source: UniProtKB-KW
- nucleotide binding Source: UniProtKB-KW
GO - Biological processi
- biosynthetic process Source: InterPro
Keywordsi
Molecular function | Nucleotidyltransferase, Transferase |
Ligand | Magnesium, Metal-binding, Nucleotide-binding |
Enzyme and pathway databases
BioCyci | BSUB:BSU07270-MONOMER |
Names & Taxonomyi
Protein namesi | Recommended name: Probable glucose-1-phosphate cytidylyltransferase (EC:2.7.7.33)Alternative name(s): CDP-glucose pyrophosphorylase |
Gene namesi | Name:yfnH Ordered Locus Names:BSU07270 |
Organismi | Bacillus subtilis (strain 168) |
Taxonomic identifieri | 224308 [NCBI] |
Taxonomic lineagei | Bacteria › Firmicutes › Bacilli › Bacillales › Bacillaceae › Bacillus › |
Proteomesi |
|
PTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
ChainiPRO_0000389445 | 1 – 254 | Probable glucose-1-phosphate cytidylyltransferaseAdd BLAST | 254 |
Proteomic databases
PaxDbi | O06486 |
PRIDEi | O06486 |
Family & Domainsi
Region
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Regioni | 6 – 10 | Substrate bindingBy similarity | 5 | |
Regioni | 11 – 13 | Substrate bindingBy similarity | 3 |
Sequence similaritiesi
Belongs to the glucose-1-phosphate cytidylyltransferase family.Curated
Phylogenomic databases
eggNOGi | COG1208, Bacteria |
InParanoidi | O06486 |
OMAi | YGAHHIK |
PhylomeDBi | O06486 |
Family and domain databases
CDDi | cd02524, G1P_cytidylyltransferase, 1 hit |
Gene3Di | 3.90.550.10, 1 hit |
InterProi | View protein in InterPro IPR013446, G1P_cyt_trans IPR005835, NTP_transferase_dom IPR029044, Nucleotide-diphossugar_trans |
Pfami | View protein in Pfam PF00483, NTP_transferase, 1 hit |
SUPFAMi | SSF53448, SSF53448, 1 hit |
i Sequence
Sequence statusi: Complete.
O06486-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MKAVILCGGK GTRMSEVTND IPKPLAMIGG KPILWHIMKI YQYYGVNEFI
60 70 80 90 100
LLLGYKGEKI KEYFLDYEWK HNSLTLDSST GEVQMLGQPE TWKITFLETG
110 120 130 140 150
VDTLTAGRIL QAKDYIGDET FLLTYGDGLA NINLFHLISY HQTKGAAATV
160 170 180 190 200
TGIDKVSQFG TLTVEDGMAK TFSEKTSSDG IINGGFFVLS PKVFDYLPKD
210 220 230 240 250
GNTMFEDEPL KNLAKDGELA VYRHYGFWTA IDTYKNLLEV NKMWNQGQQV
WKVW
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | D86418 Genomic DNA Translation: BAA20117.1 AL009126 Genomic DNA Translation: CAB12546.1 |
PIRi | C69815 |
RefSeqi | NP_388608.1, NC_000964.3 WP_003244408.1, NZ_JNCM01000032.1 |
Genome annotation databases
EnsemblBacteriai | CAB12546; CAB12546; BSU_07270 |
GeneIDi | 938779 |
KEGGi | bsu:BSU07270 |
PATRICi | fig|224308.179.peg.789 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | D86418 Genomic DNA Translation: BAA20117.1 AL009126 Genomic DNA Translation: CAB12546.1 |
PIRi | C69815 |
RefSeqi | NP_388608.1, NC_000964.3 WP_003244408.1, NZ_JNCM01000032.1 |
3D structure databases
SMRi | O06486 |
ModBasei | Search... |
Protein-protein interaction databases
STRINGi | 224308.BSU07270 |
Proteomic databases
PaxDbi | O06486 |
PRIDEi | O06486 |
Genome annotation databases
EnsemblBacteriai | CAB12546; CAB12546; BSU_07270 |
GeneIDi | 938779 |
KEGGi | bsu:BSU07270 |
PATRICi | fig|224308.179.peg.789 |
Phylogenomic databases
eggNOGi | COG1208, Bacteria |
InParanoidi | O06486 |
OMAi | YGAHHIK |
PhylomeDBi | O06486 |
Enzyme and pathway databases
BioCyci | BSUB:BSU07270-MONOMER |
Family and domain databases
CDDi | cd02524, G1P_cytidylyltransferase, 1 hit |
Gene3Di | 3.90.550.10, 1 hit |
InterProi | View protein in InterPro IPR013446, G1P_cyt_trans IPR005835, NTP_transferase_dom IPR029044, Nucleotide-diphossugar_trans |
Pfami | View protein in Pfam PF00483, NTP_transferase, 1 hit |
SUPFAMi | SSF53448, SSF53448, 1 hit |
MobiDBi | Search... |
Entry informationi
Entry namei | RFBF_BACSU | |
Accessioni | O06486Primary (citable) accession number: O06486 Secondary accession number(s): Q797B2 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | November 24, 2009 |
Last sequence update: | July 1, 1997 | |
Last modified: | April 7, 2021 | |
This is version 106 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Prokaryotic Protein Annotation Program |
Miscellaneousi
Keywords - Technical termi
Reference proteomeDocuments
- SIMILARITY comments
Index of protein domains and families