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Protein

RNA polymerase sigma factor SigV

Gene

sigV

Organism
Bacillus subtilis (strain 168)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. Positively regulates the expression of proteins involved in stress responses against bacitracin, paraquat and tellurite.1 Publication

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
DNA bindingi131 – 150H-T-H motifBy similarityAdd BLAST20

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionActivator, DNA-binding, Sigma factor
Biological processTranscription, Transcription regulation

Enzyme and pathway databases

BioCyciBSUB:BSU27120-MONOMER

Names & Taxonomyi

Protein namesi
Recommended name:
RNA polymerase sigma factor SigV
Gene namesi
Name:sigV
Ordered Locus Names:BSU27120
OrganismiBacillus subtilis (strain 168)
Taxonomic identifieri224308 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliBacillalesBacillaceaeBacillus
Proteomesi
  • UP000001570 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00000940151 – 166RNA polymerase sigma factor SigVAdd BLAST166

Proteomic databases

PaxDbiO05404
PRIDEiO05404

Interactioni

Subunit structurei

Interacts with RsiV.1 Publication

Protein-protein interaction databases

IntActiO05404, 2 interactors
STRINGi224308.Bsubs1_010100014821

Structurei

3D structure databases

ProteinModelPortaliO05404
SMRiO05404
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Motif

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Motifi38 – 51Polymerase core bindingAdd BLAST14

Sequence similaritiesi

Belongs to the sigma-70 factor family. ECF subfamily.Curated

Phylogenomic databases

eggNOGiENOG4105JVQ Bacteria
COG1595 LUCA
HOGENOMiHOG000094755
InParanoidiO05404
KOiK03088
OMAiIKSWFYK
PhylomeDBiO05404

Family and domain databases

Gene3Di1.10.10.10, 1 hit
InterProiView protein in InterPro
IPR039425 RNA_pol_sigma-70
IPR014284 RNA_pol_sigma-70_dom
IPR000838 RNA_pol_sigma70_ECF_CS
IPR007627 RNA_pol_sigma70_r2
IPR013249 RNA_pol_sigma70_r4_t2
IPR013325 RNA_pol_sigma_r2
IPR013324 RNA_pol_sigma_r3/r4-like
IPR036388 WH-like_DNA-bd_sf
PANTHERiPTHR43133 PTHR43133, 1 hit
PfamiView protein in Pfam
PF04542 Sigma70_r2, 1 hit
PF08281 Sigma70_r4_2, 1 hit
SUPFAMiSSF88659 SSF88659, 1 hit
SSF88946 SSF88946, 1 hit
TIGRFAMsiTIGR02937 sigma70-ECF, 1 hit
PROSITEiView protein in PROSITE
PS01063 SIGMA70_ECF, 1 hit

Sequencei

Sequence statusi: Complete.

O05404-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MKKKQTTKAL LVTCITDHKQ DFYRLAFSYV KNQDDALDIV QESIKKALSS
60 70 80 90 100
VETVRNPETI KSWFYKILVR TAIDFLRKQK KIRVMDDETI EFLSKGKEDH
110 120 130 140 150
YKDTDLHEAL DELPYRYKTI IILRFFEDLK LEEIAEITGE NTNTVKTRLY
160
RALKLMRIQL TKEDLS
Length:166
Mass (Da):19,713
Last modified:July 1, 1997 - v1
Checksum:iC85FE7FCB03A44AF
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U93874 Genomic DNA Translation: AAB80871.1
AL009126 Genomic DNA Translation: CAB14654.1
PIRiG69706
RefSeqiNP_390590.1, NC_000964.3
WP_004398891.1, NZ_JNCM01000036.1

Genome annotation databases

EnsemblBacteriaiCAB14654; CAB14654; BSU27120
GeneIDi937591
KEGGibsu:BSU27120
PATRICifig|224308.179.peg.2945

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U93874 Genomic DNA Translation: AAB80871.1
AL009126 Genomic DNA Translation: CAB14654.1
PIRiG69706
RefSeqiNP_390590.1, NC_000964.3
WP_004398891.1, NZ_JNCM01000036.1

3D structure databases

ProteinModelPortaliO05404
SMRiO05404
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

IntActiO05404, 2 interactors
STRINGi224308.Bsubs1_010100014821

Proteomic databases

PaxDbiO05404
PRIDEiO05404

Protocols and materials databases

DNASUi937591
Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiCAB14654; CAB14654; BSU27120
GeneIDi937591
KEGGibsu:BSU27120
PATRICifig|224308.179.peg.2945

Phylogenomic databases

eggNOGiENOG4105JVQ Bacteria
COG1595 LUCA
HOGENOMiHOG000094755
InParanoidiO05404
KOiK03088
OMAiIKSWFYK
PhylomeDBiO05404

Enzyme and pathway databases

BioCyciBSUB:BSU27120-MONOMER

Family and domain databases

Gene3Di1.10.10.10, 1 hit
InterProiView protein in InterPro
IPR039425 RNA_pol_sigma-70
IPR014284 RNA_pol_sigma-70_dom
IPR000838 RNA_pol_sigma70_ECF_CS
IPR007627 RNA_pol_sigma70_r2
IPR013249 RNA_pol_sigma70_r4_t2
IPR013325 RNA_pol_sigma_r2
IPR013324 RNA_pol_sigma_r3/r4-like
IPR036388 WH-like_DNA-bd_sf
PANTHERiPTHR43133 PTHR43133, 1 hit
PfamiView protein in Pfam
PF04542 Sigma70_r2, 1 hit
PF08281 Sigma70_r4_2, 1 hit
SUPFAMiSSF88659 SSF88659, 1 hit
SSF88946 SSF88946, 1 hit
TIGRFAMsiTIGR02937 sigma70-ECF, 1 hit
PROSITEiView protein in PROSITE
PS01063 SIGMA70_ECF, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiSIGV_BACSU
AccessioniPrimary (citable) accession number: O05404
Entry historyiIntegrated into UniProtKB/Swiss-Prot: July 15, 1998
Last sequence update: July 1, 1997
Last modified: November 7, 2018
This is version 122 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
  2. Bacillus subtilis
    Bacillus subtilis (strain 168): entries, gene names and cross-references to SubtiList
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Main funding by: National Institutes of Health

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