UniProtKB - O04619 (ADNT1_ARATH)
Mitochondrial adenine nucleotide transporter ADNT1
ADNT1
Functioni
Mitochondrial adenylate carrier that catalyzes specifically the transport of ATP, ADP and AMP by a counter-exchange mechanism across the inner mitochondrial membrane. Substrate preference in reconstituted proteoliposomes is ATP > AMP > ADP. May play a role in oxidative phosphorylation and be important for the provision of energy required to support growth in heterotrophic tissues.
1 PublicationActivity regulationi
GO - Molecular functioni
- antiporter activity Source: UniProtKB-KW
Keywordsi
Biological process | Antiport, Transport |
Protein family/group databases
TCDBi | 2.A.29.23.4, the mitochondrial carrier (mc) family |
Names & Taxonomyi
Protein namesi | Recommended name: Mitochondrial adenine nucleotide transporter ADNT1Alternative name(s): Adenine nucleotide transporter 1 |
Gene namesi | Name:ADNT1 Ordered Locus Names:At4g01100 ORF Names:A_IG002N01.16, F2N1.16 |
Organismi | Arabidopsis thaliana (Mouse-ear cress) |
Taxonomic identifieri | 3702 [NCBI] |
Taxonomic lineagei | Eukaryota › Viridiplantae › Streptophyta › Embryophyta › Tracheophyta › Spermatophyta › Magnoliopsida › eudicotyledons › Gunneridae › Pentapetalae › rosids › malvids › Brassicales › Brassicaceae › Camelineae › Arabidopsis |
Proteomesi |
|
Organism-specific databases
Araporti | AT4G01100 |
Subcellular locationi
Mitochondrion
- Mitochondrion inner membrane 1 Publication; Multi-pass membrane protein 1 Publication
Mitochondrion
- mitochondrial inner membrane Source: UniProtKB-SubCell
Other locations
- integral component of membrane Source: UniProtKB-KW
Topology
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Transmembranei | 41 – 61 | Helical; Name=1Sequence analysisAdd BLAST | 21 | |
Transmembranei | 100 – 120 | Helical; Name=2Sequence analysisAdd BLAST | 21 | |
Transmembranei | 145 – 162 | Helical; Name=3Sequence analysisAdd BLAST | 18 | |
Transmembranei | 202 – 221 | Helical; Name=4Sequence analysisAdd BLAST | 20 | |
Transmembranei | 242 – 263 | Helical; Name=5Sequence analysisAdd BLAST | 22 | |
Transmembranei | 324 – 340 | Helical; Name=6Sequence analysisAdd BLAST | 17 |
Keywords - Cellular componenti
Membrane, Mitochondrion, Mitochondrion inner membranePathology & Biotechi
Disruption phenotypei
PTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
ChainiPRO_0000420757 | 1 – 352 | Mitochondrial adenine nucleotide transporter ADNT1Add BLAST | 352 |
Proteomic databases
PaxDbi | O04619 |
PRIDEi | O04619 |
ProteomicsDBi | 244927 [O04619-1] |
PTM databases
iPTMneti | O04619 |
MetOSitei | O04619 |
Expressioni
Tissue specificityi
Gene expression databases
ExpressionAtlasi | O04619, baseline and differential |
Genevisiblei | O04619, AT |
Interactioni
Protein-protein interaction databases
IntActi | O04619, 1 interactor |
STRINGi | 3702.AT4G01100.2 |
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Repeati | 36 – 123 | Solcar 1Add BLAST | 88 | |
Repeati | 139 – 227 | Solcar 2Add BLAST | 89 | |
Repeati | 242 – 343 | Solcar 3Add BLAST | 102 |
Sequence similaritiesi
Keywords - Domaini
Repeat, Transmembrane, Transmembrane helixPhylogenomic databases
eggNOGi | KOG0752, Eukaryota |
HOGENOMi | CLU_015166_10_3_1 |
InParanoidi | O04619 |
PhylomeDBi | O04619 |
Family and domain databases
Gene3Di | 1.50.40.10, 1 hit |
InterProi | View protein in InterPro IPR002067, Mit_carrier IPR018108, Mitochondrial_sb/sol_carrier IPR023395, Mt_carrier_dom_sf |
Pfami | View protein in Pfam PF00153, Mito_carr, 3 hits |
PRINTSi | PR00926, MITOCARRIER |
SUPFAMi | SSF103506, SSF103506, 1 hit |
PROSITEi | View protein in PROSITE PS50920, SOLCAR, 3 hits |
(1+)i Sequence
Sequence statusi: Complete.
This entry describes 1 produced by isoform ialternative splicing. AlignAdd to basketThis entry has 1 described isoform and 2 potential isoforms that are computationally mapped.Show allAlign All
This isoform has been chosen as the sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry. canonicali
10 20 30 40 50
MASEDVKRTE SAAVSTIVNL AEEAREGVKA PSYAFKSICK SLFAGGVAGG
60 70 80 90 100
VSRTAVAPLE RMKILLQVQN PHNIKYSGTV QGLKHIWRTE GLRGLFKGNG
110 120 130 140 150
TNCARIVPNS AVKFFSYEQA SNGILYMYRQ RTGNENAQLT PLLRLGAGAT
160 170 180 190 200
AGIIAMSATY PMDMVRGRLT VQTANSPYQY RGIAHALATV LREEGPRALY
210 220 230 240 250
RGWLPSVIGV VPYVGLNFSV YESLKDWLVK ENPYGLVENN ELTVVTRLTC
260 270 280 290 300
GAIAGTVGQT IAYPLDVIRR RMQMVGWKDA SAIVTGEGRS TASLEYTGMV
310 320 330 340 350
DAFRKTVRHE GFGALYKGLV PNSVKVVPSI AIAFVTYEMV KDVLGVEFRI
SD
Computationally mapped potential isoform sequencesi
There are 2 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basketF4JHS4 | F4JHS4_ARATH | Adenine nucleotide transporter 1 | ADNT1 At4g01100, F2N1.16, F2N1_16 | 366 | Annotation score: | ||
A0A1P8B4I5 | A0A1P8B4I5_ARATH | Adenine nucleotide transporter 1 | ADNT1 At4g01100, F2N1.16, F2N1_16 | 302 | Annotation score: |
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AM931440 mRNA Translation: CAP64296.1 AF007269 Genomic DNA Translation: AAB61037.1 AL161491 Genomic DNA Translation: CAB80919.1 CP002687 Genomic DNA Translation: AEE81981.1 AF360168 mRNA Translation: AAK25878.1 AF412085 mRNA Translation: AAL06538.1 AY056343 mRNA Translation: AAL07192.1 |
PIRi | T01729 |
RefSeqi | NP_192019.1, NM_116340.4 [O04619-1] |
Genome annotation databases
EnsemblPlantsi | AT4G01100.1; AT4G01100.1; AT4G01100 [O04619-1] |
GeneIDi | 827899 |
Gramenei | AT4G01100.1; AT4G01100.1; AT4G01100 [O04619-1] |
KEGGi | ath:AT4G01100 |
Keywords - Coding sequence diversityi
Alternative splicingSimilar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AM931440 mRNA Translation: CAP64296.1 AF007269 Genomic DNA Translation: AAB61037.1 AL161491 Genomic DNA Translation: CAB80919.1 CP002687 Genomic DNA Translation: AEE81981.1 AF360168 mRNA Translation: AAK25878.1 AF412085 mRNA Translation: AAL06538.1 AY056343 mRNA Translation: AAL07192.1 |
PIRi | T01729 |
RefSeqi | NP_192019.1, NM_116340.4 [O04619-1] |
3D structure databases
AlphaFoldDBi | O04619 |
SMRi | O04619 |
ModBasei | Search... |
Protein-protein interaction databases
IntActi | O04619, 1 interactor |
STRINGi | 3702.AT4G01100.2 |
Protein family/group databases
TCDBi | 2.A.29.23.4, the mitochondrial carrier (mc) family |
PTM databases
iPTMneti | O04619 |
MetOSitei | O04619 |
Proteomic databases
PaxDbi | O04619 |
PRIDEi | O04619 |
ProteomicsDBi | 244927 [O04619-1] |
Protocols and materials databases
DNASUi | 827899 |
Genome annotation databases
EnsemblPlantsi | AT4G01100.1; AT4G01100.1; AT4G01100 [O04619-1] |
GeneIDi | 827899 |
Gramenei | AT4G01100.1; AT4G01100.1; AT4G01100 [O04619-1] |
KEGGi | ath:AT4G01100 |
Organism-specific databases
Araporti | AT4G01100 |
Phylogenomic databases
eggNOGi | KOG0752, Eukaryota |
HOGENOMi | CLU_015166_10_3_1 |
InParanoidi | O04619 |
PhylomeDBi | O04619 |
Miscellaneous databases
PROi | PR:O04619 |
Gene expression databases
ExpressionAtlasi | O04619, baseline and differential |
Genevisiblei | O04619, AT |
Family and domain databases
Gene3Di | 1.50.40.10, 1 hit |
InterProi | View protein in InterPro IPR002067, Mit_carrier IPR018108, Mitochondrial_sb/sol_carrier IPR023395, Mt_carrier_dom_sf |
Pfami | View protein in Pfam PF00153, Mito_carr, 3 hits |
PRINTSi | PR00926, MITOCARRIER |
SUPFAMi | SSF103506, SSF103506, 1 hit |
PROSITEi | View protein in PROSITE PS50920, SOLCAR, 3 hits |
MobiDBi | Search... |
Entry informationi
Entry namei | ADNT1_ARATH | |
Accessioni | O04619Primary (citable) accession number: O04619 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | January 9, 2013 |
Last sequence update: | July 1, 1997 | |
Last modified: | May 25, 2022 | |
This is version 147 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Plant Protein Annotation Program |
Miscellaneousi
Keywords - Technical termi
Reference proteomeDocuments
- Arabidopsis thaliana
Arabidopsis thaliana: entries and gene names - SIMILARITY comments
Index of protein domains and families