We will be switching to the new UniProt website on Tuesday, June 28. Please explore and share your feedback.
Take me to UniProt BETA
UniProtKB - O04403 (NLT22_PARJU)
Protein
Probable non-specific lipid-transfer protein 2
Gene
N/A
Organism
Parietaria judaica (Pellitory-of-the-wall) (Parietaria diffusa)
Status
Functioni
Plant non-specific lipid-transfer proteins transfer phospholipids as well as galactolipids across membranes. May play a role in wax or cutin deposition in the cell walls of expanding epidermal cells and certain secretory tissues.
GO - Molecular functioni
- lipid binding Source: UniProtKB-KW
GO - Biological processi
- lipid transport Source: InterPro
Keywordsi
Biological process | Transport |
Ligand | Lipid-binding |
Names & Taxonomyi
Protein namesi | Recommended name: Probable non-specific lipid-transfer protein 2Short name: LTP 2 Alternative name(s): Allergen Par j II Major pollen allergen Par j 2.0102 Protein P8 Allergen: Par j 2.0102 |
Organismi | Parietaria judaica (Pellitory-of-the-wall) (Parietaria diffusa) |
Taxonomic identifieri | 33127 [NCBI] |
Taxonomic lineagei | Eukaryota › Viridiplantae › Streptophyta › Embryophyta › Tracheophyta › Spermatophyta › Magnoliopsida › eudicotyledons › Gunneridae › Pentapetalae › rosids › fabids › Rosales › Urticaceae › Parietaria |
Pathology & Biotechi
Allergenic propertiesi
Causes an allergic reaction in human. Binds to IgE and induces histamine release from basophils of Pj-pollen-allergic subjects.
Keywords - Diseasei
AllergenProtein family/group databases
Allergomei | 507, Par j 2 509, Par j 2.0102 |
PTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Signal peptidei | 1 – 31 | Sequence analysisAdd BLAST | 31 | |
ChainiPRO_0000018399 | 32 – 133 | Probable non-specific lipid-transfer protein 2Add BLAST | 102 |
Amino acid modifications
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Disulfide bondi | 35 ↔ 83 | By similarity | ||
Disulfide bondi | 45 ↔ 60 | By similarity | ||
Disulfide bondi | 61 ↔ 106 | By similarity | ||
Disulfide bondi | 81 ↔ 121 | By similarity |
Keywords - PTMi
Disulfide bondProteomic databases
PRIDEi | O04403 |
Family & Domainsi
Sequence similaritiesi
Belongs to the plant LTP family.Curated
Keywords - Domaini
SignalFamily and domain databases
Gene3Di | 1.10.110.10, 1 hit |
InterProi | View protein in InterPro IPR036312, Bifun_inhib/LTP/seed_sf IPR016140, Bifunc_inhib/LTP/seed_store IPR000528, Plant_nsLTP |
PANTHERi | PTHR33076, PTHR33076, 1 hit |
Pfami | View protein in Pfam PF14368, LTP_2, 1 hit |
PRINTSi | PR00382, LIPIDTRNSFER |
SMARTi | View protein in SMART SM00499, AAI, 1 hit |
SUPFAMi | SSF47699, SSF47699, 1 hit |
PROSITEi | View protein in PROSITE PS00597, PLANT_LTP, 1 hit |
i Sequence
Sequence statusi: Complete.
: The displayed sequence is further processed into a mature form. Sequence processingi
O04403-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MRTVSMAALV VIAAALAWTS SAELASAPAP GEGPCGKVVH HIMPCLKFVK
60 70 80 90 100
GEEKEPSKSC CSGTKKLSEE VKTTEQKREA CKCIVAATKG ISGIKNELVA
110 120 130
EVPKKCGITT TLPPITADFD CSKIESTIFR GYY
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | X95866 mRNA Translation: CAA65122.1 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | X95866 mRNA Translation: CAA65122.1 |
3D structure databases
AlphaFoldDBi | O04403 |
SMRi | O04403 |
ModBasei | Search... |
Protein family/group databases
Allergomei | 507, Par j 2 509, Par j 2.0102 |
Proteomic databases
PRIDEi | O04403 |
Family and domain databases
Gene3Di | 1.10.110.10, 1 hit |
InterProi | View protein in InterPro IPR036312, Bifun_inhib/LTP/seed_sf IPR016140, Bifunc_inhib/LTP/seed_store IPR000528, Plant_nsLTP |
PANTHERi | PTHR33076, PTHR33076, 1 hit |
Pfami | View protein in Pfam PF14368, LTP_2, 1 hit |
PRINTSi | PR00382, LIPIDTRNSFER |
SMARTi | View protein in SMART SM00499, AAI, 1 hit |
SUPFAMi | SSF47699, SSF47699, 1 hit |
PROSITEi | View protein in PROSITE PS00597, PLANT_LTP, 1 hit |
MobiDBi | Search... |
Entry informationi
Entry namei | NLT22_PARJU | |
Accessioni | O04403Primary (citable) accession number: O04403 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | December 15, 1998 |
Last sequence update: | July 1, 1997 | |
Last modified: | May 25, 2022 | |
This is version 70 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Plant Protein Annotation Program |
Miscellaneousi
Documents
- Allergens
Nomenclature of allergens and list of entries - SIMILARITY comments
Index of protein domains and families