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Entry version 141 (23 Feb 2022)
Sequence version 1 (01 Jul 1997)
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Protein

Sugar transport protein 7

Gene

STP7

Organism
Arabidopsis thaliana (Mouse-ear cress)
Status
Reviewed-Annotation score:

Annotation score:3 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Mediates an active uptake of hexoses, probably by sugar/hydrogen symport.

By similarity

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Biological processSugar transport, Symport, Transport

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Sugar transport protein 7
Alternative name(s):
Hexose transporter 7
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:STP7
Ordered Locus Names:At4g02050
ORF Names:AGAA.1, T10M13.6
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiArabidopsis thaliana (Mouse-ear cress)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri3702 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliopsidaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeCamelineaeArabidopsis
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000006548 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 4

Organism-specific databases

Arabidopsis Information Portal

More...
Araporti
AT4G02050

The Arabidopsis Information Resource

More...
TAIRi
locus:2132213, AT4G02050

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/subcellular%5Flocation%5Fsection">'Subcellular location'</a> section describes the subcellular compartment where each non-membrane region of a membrane-spanning protein is found.<p><a href='/help/topo_dom' target='_top'>More...</a></p>Topological domaini1 – 26CytoplasmicSequence analysisAdd BLAST26
<p>This subsection of the <a href="http://www.uniprot.org/help/subcellular%5Flocation%5Fsection">'Subcellular location'</a> section describes the extent of a membrane-spanning region of the protein. It denotes the presence of both alpha-helical transmembrane regions and the membrane spanning regions of beta-barrel transmembrane proteins.<p><a href='/help/transmem' target='_top'>More...</a></p>Transmembranei27 – 47Helical; Name=1Sequence analysisAdd BLAST21
Transmembranei84 – 104Helical; Name=2Sequence analysisAdd BLAST21
Transmembranei121 – 141Helical; Name=3Sequence analysisAdd BLAST21
Transmembranei144 – 164Helical; Name=4Sequence analysisAdd BLAST21
Transmembranei171 – 191Helical; Name=5Sequence analysisAdd BLAST21
Transmembranei205 – 225Helical; Name=6Sequence analysisAdd BLAST21
Transmembranei286 – 306Helical; Name=7Sequence analysisAdd BLAST21
Transmembranei324 – 344Helical; Name=8Sequence analysisAdd BLAST21
Transmembranei351 – 371Helical; Name=9Sequence analysisAdd BLAST21
Transmembranei387 – 407Helical; Name=10Sequence analysisAdd BLAST21
Transmembranei427 – 447Helical; Name=11Sequence analysisAdd BLAST21
Transmembranei452 – 472Helical; Name=12Sequence analysisAdd BLAST21
Topological domaini473 – 513CytoplasmicSequence analysisAdd BLAST41

Keywords - Cellular componenti

Cell membrane, Membrane

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00000504371 – 513Sugar transport protein 7Add BLAST513

Proteomic databases

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
O04249

ProteomicsDB: a multi-organism proteome resource

More...
ProteomicsDBi
228268

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

ExpressionAtlas, Differential and Baseline Expression

More...
ExpressionAtlasi
O04249, baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
O04249, AT

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGRID)

More...
BioGRIDi
13443, 2 interactors

STRING: functional protein association networks

More...
STRINGi
3702.AT4G02050.1

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
O04249

Database of comparative protein structure models

More...
ModBasei
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

<p>This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG0254, Eukaryota

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
CLU_001265_30_5_1

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
O04249

Identification of Orthologs from Complete Genome Data

More...
OMAi
AQSANWF

Database of Orthologous Groups

More...
OrthoDBi
430696at2759

Database for complete collections of gene phylogenies

More...
PhylomeDBi
O04249

Family and domain databases

Conserved Domains Database

More...
CDDi
cd17361, MFS_STP, 1 hit

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
1.20.1250.20, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR020846, MFS_dom
IPR044778, MFS_STP/MST-like_plant
IPR005828, MFS_sugar_transport-like
IPR036259, MFS_trans_sf
IPR045262, STP/PLT_plant
IPR003663, Sugar/inositol_transpt
IPR005829, Sugar_transporter_CS

The PANTHER Classification System

More...
PANTHERi
PTHR23500, PTHR23500, 1 hit

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF00083, Sugar_tr, 1 hit

Protein Motif fingerprint database; a protein domain database

More...
PRINTSi
PR00171, SUGRTRNSPORT

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF103473, SSF103473, 1 hit

TIGRFAMs; a protein family database

More...
TIGRFAMsi
TIGR00879, SP, 1 hit

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS50850, MFS, 1 hit
PS00216, SUGAR_TRANSPORT_1, 1 hit
PS00217, SUGAR_TRANSPORT_2, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

O04249-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MAGGSFGPTG VAKERAEQYQ GKVTSYVIIA CLVAAIGGSI FGYDIGISGG
60 70 80 90 100
VTSMDEFLEE FFHTVYEKKK QAHESNYCKY DNQGLAAFTS SLYLAGLVST
110 120 130 140 150
LVASPITRNY GRRASIVCGG ISFLIGSGLN AGAVNLAMLL AGRIMLGVGI
160 170 180 190 200
GFGNQAVPLY LSEVAPTHLR GGLNMMFQLA TTIGIFTANM VNYGTQQLKP
210 220 230 240 250
WGWRLSLGLA AFPALLMTLG GYFLPETPNS LVERGLTERG RRVLVKLRGT
260 270 280 290 300
ENVNAELQDM VDASELANSI KHPFRNILQK RHRPQLVMAI CMPMFQILTG
310 320 330 340 350
INSILFYAPV LFQTMGFGGN ASLYSSALTG AVLVLSTFIS IGLVDRLGRR
360 370 380 390 400
ALLITGGIQM IICQVIVAVI LGVKFGDNQE LSKGYSVIVV IFICLFVVAF
410 420 430 440 450
GWSWGPLGWT IPSEIFPLET RSAGQSITVA VNLLFTFIIA QAFLGLLCAF
460 470 480 490 500
KFGIFLFFAG WVTVMTIFVY FLLPETKGVP IEEMTLLWSK HWFWKKVLPD
510
ATNLEDESKN VSV
Length:513
Mass (Da):55,829
Last modified:July 1, 1997 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iA5570287432C442C
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti233E → D in AAB57796 (Ref. 4) Curated1
Sequence conflicti439I → V in CAA04905 (Ref. 5) Curated1

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

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GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AJ344331 mRNA Translation: CAC69067.1
AF001308 Genomic DNA Translation: AAC78697.1
AL161493 Genomic DNA Translation: CAB80698.1
CP002687 Genomic DNA Translation: AEE82116.1
CP002687 Genomic DNA Translation: ANM67604.1
AF001535 Genomic DNA Translation: AAB57796.1
AJ001660 Genomic DNA Translation: CAA04905.1

Protein sequence database of the Protein Information Resource

More...
PIRi
T01506

NCBI Reference Sequences

More...
RefSeqi
NP_001329423.1, NM_001340358.1
NP_192114.1, NM_116436.6

Genome annotation databases

Ensembl plant genome annotation project

More...
EnsemblPlantsi
AT4G02050.1; AT4G02050.1; AT4G02050
AT4G02050.2; AT4G02050.2; AT4G02050

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
828154

Gramene; a comparative resource for plants

More...
Gramenei
AT4G02050.1; AT4G02050.1; AT4G02050
AT4G02050.2; AT4G02050.2; AT4G02050

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
ath:AT4G02050

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AJ344331 mRNA Translation: CAC69067.1
AF001308 Genomic DNA Translation: AAC78697.1
AL161493 Genomic DNA Translation: CAB80698.1
CP002687 Genomic DNA Translation: AEE82116.1
CP002687 Genomic DNA Translation: ANM67604.1
AF001535 Genomic DNA Translation: AAB57796.1
AJ001660 Genomic DNA Translation: CAA04905.1
PIRiT01506
RefSeqiNP_001329423.1, NM_001340358.1
NP_192114.1, NM_116436.6

3D structure databases

SMRiO04249
ModBaseiSearch...

Protein-protein interaction databases

BioGRIDi13443, 2 interactors
STRINGi3702.AT4G02050.1

Proteomic databases

PaxDbiO04249
ProteomicsDBi228268

Genome annotation databases

EnsemblPlantsiAT4G02050.1; AT4G02050.1; AT4G02050
AT4G02050.2; AT4G02050.2; AT4G02050
GeneIDi828154
GrameneiAT4G02050.1; AT4G02050.1; AT4G02050
AT4G02050.2; AT4G02050.2; AT4G02050
KEGGiath:AT4G02050

Organism-specific databases

AraportiAT4G02050
TAIRilocus:2132213, AT4G02050

Phylogenomic databases

eggNOGiKOG0254, Eukaryota
HOGENOMiCLU_001265_30_5_1
InParanoidiO04249
OMAiAQSANWF
OrthoDBi430696at2759
PhylomeDBiO04249

Miscellaneous databases

Protein Ontology

More...
PROi
PR:O04249

Gene expression databases

ExpressionAtlasiO04249, baseline and differential
GenevisibleiO04249, AT

Family and domain databases

CDDicd17361, MFS_STP, 1 hit
Gene3Di1.20.1250.20, 1 hit
InterProiView protein in InterPro
IPR020846, MFS_dom
IPR044778, MFS_STP/MST-like_plant
IPR005828, MFS_sugar_transport-like
IPR036259, MFS_trans_sf
IPR045262, STP/PLT_plant
IPR003663, Sugar/inositol_transpt
IPR005829, Sugar_transporter_CS
PANTHERiPTHR23500, PTHR23500, 1 hit
PfamiView protein in Pfam
PF00083, Sugar_tr, 1 hit
PRINTSiPR00171, SUGRTRNSPORT
SUPFAMiSSF103473, SSF103473, 1 hit
TIGRFAMsiTIGR00879, SP, 1 hit
PROSITEiView protein in PROSITE
PS50850, MFS, 1 hit
PS00216, SUGAR_TRANSPORT_1, 1 hit
PS00217, SUGAR_TRANSPORT_2, 1 hit

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiSTP7_ARATH
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: O04249
Secondary accession number(s): O04262, O81705
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: January 24, 2006
Last sequence update: July 1, 1997
Last modified: February 23, 2022
This is version 141 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteome

Documents

  1. Arabidopsis thaliana
    Arabidopsis thaliana: entries and gene names
  2. SIMILARITY comments
    Index of protein domains and families
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