We will be switching to the new UniProt website soon. Please explore and share your feedback.
Take me to the new website.
UniProtKB - O04249 (STP7_ARATH)
Protein
Sugar transport protein 7
Gene
STP7
Organism
Arabidopsis thaliana (Mouse-ear cress)
Status
Functioni
Mediates an active uptake of hexoses, probably by sugar/hydrogen symport.
By similarityGO - Molecular functioni
- arabinose transmembrane transporter activity Source: TAIR
- symporter activity Source: UniProtKB-KW
GO - Biological processi
- L-arabinose transmembrane transport Source: TAIR
Keywordsi
Biological process | Sugar transport, Symport, Transport |
Names & Taxonomyi
Protein namesi | Recommended name: Sugar transport protein 7Alternative name(s): Hexose transporter 7 |
Gene namesi | Name:STP7 Ordered Locus Names:At4g02050 ORF Names:AGAA.1, T10M13.6 |
Organismi | Arabidopsis thaliana (Mouse-ear cress) |
Taxonomic identifieri | 3702 [NCBI] |
Taxonomic lineagei | Eukaryota › Viridiplantae › Streptophyta › Embryophyta › Tracheophyta › Spermatophyta › Magnoliopsida › eudicotyledons › Gunneridae › Pentapetalae › rosids › malvids › Brassicales › Brassicaceae › Camelineae › Arabidopsis |
Proteomesi |
|
Organism-specific databases
Araporti | AT4G02050 |
TAIRi | locus:2132213, AT4G02050 |
Subcellular locationi
Plasma membrane
- Cell membrane 1 Publication; Multi-pass membrane protein Sequence analysis
Plasma Membrane
- plasma membrane Source: TAIR
Other locations
- endomembrane system Source: TAIR
- integral component of membrane Source: UniProtKB-KW
- pollen tube Source: TAIR
Topology
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Topological domaini | 1 – 26 | CytoplasmicSequence analysisAdd BLAST | 26 | |
Transmembranei | 27 – 47 | Helical; Name=1Sequence analysisAdd BLAST | 21 | |
Transmembranei | 84 – 104 | Helical; Name=2Sequence analysisAdd BLAST | 21 | |
Transmembranei | 121 – 141 | Helical; Name=3Sequence analysisAdd BLAST | 21 | |
Transmembranei | 144 – 164 | Helical; Name=4Sequence analysisAdd BLAST | 21 | |
Transmembranei | 171 – 191 | Helical; Name=5Sequence analysisAdd BLAST | 21 | |
Transmembranei | 205 – 225 | Helical; Name=6Sequence analysisAdd BLAST | 21 | |
Transmembranei | 286 – 306 | Helical; Name=7Sequence analysisAdd BLAST | 21 | |
Transmembranei | 324 – 344 | Helical; Name=8Sequence analysisAdd BLAST | 21 | |
Transmembranei | 351 – 371 | Helical; Name=9Sequence analysisAdd BLAST | 21 | |
Transmembranei | 387 – 407 | Helical; Name=10Sequence analysisAdd BLAST | 21 | |
Transmembranei | 427 – 447 | Helical; Name=11Sequence analysisAdd BLAST | 21 | |
Transmembranei | 452 – 472 | Helical; Name=12Sequence analysisAdd BLAST | 21 | |
Topological domaini | 473 – 513 | CytoplasmicSequence analysisAdd BLAST | 41 |
Keywords - Cellular componenti
Cell membrane, MembranePTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
ChainiPRO_0000050437 | 1 – 513 | Sugar transport protein 7Add BLAST | 513 |
Proteomic databases
PaxDbi | O04249 |
ProteomicsDBi | 228268 |
Expressioni
Gene expression databases
ExpressionAtlasi | O04249, baseline and differential |
Genevisiblei | O04249, AT |
Interactioni
Protein-protein interaction databases
BioGRIDi | 13443, 2 interactors |
STRINGi | 3702.AT4G02050.1 |
Family & Domainsi
Sequence similaritiesi
Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. [View classification]Curated
Keywords - Domaini
Transmembrane, Transmembrane helixPhylogenomic databases
eggNOGi | KOG0254, Eukaryota |
HOGENOMi | CLU_001265_30_5_1 |
InParanoidi | O04249 |
OMAi | AQSANWF |
OrthoDBi | 430696at2759 |
PhylomeDBi | O04249 |
Family and domain databases
CDDi | cd17361, MFS_STP, 1 hit |
Gene3Di | 1.20.1250.20, 1 hit |
InterProi | View protein in InterPro IPR020846, MFS_dom IPR044778, MFS_STP/MST-like_plant IPR005828, MFS_sugar_transport-like IPR036259, MFS_trans_sf IPR045262, STP/PLT_plant IPR003663, Sugar/inositol_transpt IPR005829, Sugar_transporter_CS |
PANTHERi | PTHR23500, PTHR23500, 1 hit |
Pfami | View protein in Pfam PF00083, Sugar_tr, 1 hit |
PRINTSi | PR00171, SUGRTRNSPORT |
SUPFAMi | SSF103473, SSF103473, 1 hit |
TIGRFAMsi | TIGR00879, SP, 1 hit |
PROSITEi | View protein in PROSITE PS50850, MFS, 1 hit PS00216, SUGAR_TRANSPORT_1, 1 hit PS00217, SUGAR_TRANSPORT_2, 1 hit |
i Sequence
Sequence statusi: Complete.
O04249-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MAGGSFGPTG VAKERAEQYQ GKVTSYVIIA CLVAAIGGSI FGYDIGISGG
60 70 80 90 100
VTSMDEFLEE FFHTVYEKKK QAHESNYCKY DNQGLAAFTS SLYLAGLVST
110 120 130 140 150
LVASPITRNY GRRASIVCGG ISFLIGSGLN AGAVNLAMLL AGRIMLGVGI
160 170 180 190 200
GFGNQAVPLY LSEVAPTHLR GGLNMMFQLA TTIGIFTANM VNYGTQQLKP
210 220 230 240 250
WGWRLSLGLA AFPALLMTLG GYFLPETPNS LVERGLTERG RRVLVKLRGT
260 270 280 290 300
ENVNAELQDM VDASELANSI KHPFRNILQK RHRPQLVMAI CMPMFQILTG
310 320 330 340 350
INSILFYAPV LFQTMGFGGN ASLYSSALTG AVLVLSTFIS IGLVDRLGRR
360 370 380 390 400
ALLITGGIQM IICQVIVAVI LGVKFGDNQE LSKGYSVIVV IFICLFVVAF
410 420 430 440 450
GWSWGPLGWT IPSEIFPLET RSAGQSITVA VNLLFTFIIA QAFLGLLCAF
460 470 480 490 500
KFGIFLFFAG WVTVMTIFVY FLLPETKGVP IEEMTLLWSK HWFWKKVLPD
510
ATNLEDESKN VSV
Experimental Info
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Sequence conflicti | 233 | E → D in AAB57796 (Ref. 4) Curated | 1 | |
Sequence conflicti | 439 | I → V in CAA04905 (Ref. 5) Curated | 1 |
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AJ344331 mRNA Translation: CAC69067.1 AF001308 Genomic DNA Translation: AAC78697.1 AL161493 Genomic DNA Translation: CAB80698.1 CP002687 Genomic DNA Translation: AEE82116.1 CP002687 Genomic DNA Translation: ANM67604.1 AF001535 Genomic DNA Translation: AAB57796.1 AJ001660 Genomic DNA Translation: CAA04905.1 |
PIRi | T01506 |
RefSeqi | NP_001329423.1, NM_001340358.1 NP_192114.1, NM_116436.6 |
Genome annotation databases
EnsemblPlantsi | AT4G02050.1; AT4G02050.1; AT4G02050 AT4G02050.2; AT4G02050.2; AT4G02050 |
GeneIDi | 828154 |
Gramenei | AT4G02050.1; AT4G02050.1; AT4G02050 AT4G02050.2; AT4G02050.2; AT4G02050 |
KEGGi | ath:AT4G02050 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AJ344331 mRNA Translation: CAC69067.1 AF001308 Genomic DNA Translation: AAC78697.1 AL161493 Genomic DNA Translation: CAB80698.1 CP002687 Genomic DNA Translation: AEE82116.1 CP002687 Genomic DNA Translation: ANM67604.1 AF001535 Genomic DNA Translation: AAB57796.1 AJ001660 Genomic DNA Translation: CAA04905.1 |
PIRi | T01506 |
RefSeqi | NP_001329423.1, NM_001340358.1 NP_192114.1, NM_116436.6 |
3D structure databases
SMRi | O04249 |
ModBasei | Search... |
Protein-protein interaction databases
BioGRIDi | 13443, 2 interactors |
STRINGi | 3702.AT4G02050.1 |
Proteomic databases
PaxDbi | O04249 |
ProteomicsDBi | 228268 |
Genome annotation databases
EnsemblPlantsi | AT4G02050.1; AT4G02050.1; AT4G02050 AT4G02050.2; AT4G02050.2; AT4G02050 |
GeneIDi | 828154 |
Gramenei | AT4G02050.1; AT4G02050.1; AT4G02050 AT4G02050.2; AT4G02050.2; AT4G02050 |
KEGGi | ath:AT4G02050 |
Organism-specific databases
Araporti | AT4G02050 |
TAIRi | locus:2132213, AT4G02050 |
Phylogenomic databases
eggNOGi | KOG0254, Eukaryota |
HOGENOMi | CLU_001265_30_5_1 |
InParanoidi | O04249 |
OMAi | AQSANWF |
OrthoDBi | 430696at2759 |
PhylomeDBi | O04249 |
Miscellaneous databases
PROi | PR:O04249 |
Gene expression databases
ExpressionAtlasi | O04249, baseline and differential |
Genevisiblei | O04249, AT |
Family and domain databases
CDDi | cd17361, MFS_STP, 1 hit |
Gene3Di | 1.20.1250.20, 1 hit |
InterProi | View protein in InterPro IPR020846, MFS_dom IPR044778, MFS_STP/MST-like_plant IPR005828, MFS_sugar_transport-like IPR036259, MFS_trans_sf IPR045262, STP/PLT_plant IPR003663, Sugar/inositol_transpt IPR005829, Sugar_transporter_CS |
PANTHERi | PTHR23500, PTHR23500, 1 hit |
Pfami | View protein in Pfam PF00083, Sugar_tr, 1 hit |
PRINTSi | PR00171, SUGRTRNSPORT |
SUPFAMi | SSF103473, SSF103473, 1 hit |
TIGRFAMsi | TIGR00879, SP, 1 hit |
PROSITEi | View protein in PROSITE PS50850, MFS, 1 hit PS00216, SUGAR_TRANSPORT_1, 1 hit PS00217, SUGAR_TRANSPORT_2, 1 hit |
MobiDBi | Search... |
Entry informationi
Entry namei | STP7_ARATH | |
Accessioni | O04249Primary (citable) accession number: O04249 Secondary accession number(s): O04262, O81705 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | January 24, 2006 |
Last sequence update: | July 1, 1997 | |
Last modified: | February 23, 2022 | |
This is version 141 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Plant Protein Annotation Program |
Miscellaneousi
Keywords - Technical termi
Reference proteomeDocuments
- Arabidopsis thaliana
Arabidopsis thaliana: entries and gene names - SIMILARITY comments
Index of protein domains and families