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Entry version 163 (26 Feb 2020)
Sequence version 1 (01 Jul 1997)
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Protein

Males-absent on the first protein

Gene

mof

Organism
Drosophila melanogaster (Fruit fly)
Status
Reviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Histone acetyltransferase that plays a direct role in the specific histone acetylation associated with dosage compensation as part of the MSL complex (PubMed:9155031, PubMed:16543150). Dosage compensation insures that males with a single X chromosome have the same amount of most X-linked gene products as females with two X chromosomes (PubMed:9155031). May be directly involved in the acetylation of histone 4 at 'Lys-16' on the X chromosome of males where it is recruited by the MSL complex (PubMed:11258702). As part of the NSL complex may associate with promoters of X chromosomal as well as autosomal genes and positively regulate their transcription through chromatin modification (PubMed:20620954).4 Publications

<p>This subsection of the <a href="http://www.uniprot.org/help/function%5Fsection">Function</a> section describes the catalytic activity of an enzyme, i.e. a chemical reaction that the enzyme catalyzes.<p><a href='/help/catalytic_activity' target='_top'>More...</a></p>Catalytic activityi

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/function%5Fsection">Function</a> section is used for enzymes and indicates the residues directly involved in catalysis.<p><a href='/help/act_site' target='_top'>More...</a></p>Active sitei714Proton donor/acceptorBy similarity1
<p>This subsection of the <a href="http://www.uniprot.org/help/function%5Fsection">Function</a> section describes the interaction between a single amino acid and another chemical entity. Priority is given to the annotation of physiological ligands.<p><a href='/help/binding' target='_top'>More...</a></p>Binding sitei718Acetyl-CoABy similarity1
Binding sitei727Acetyl-CoABy similarity1
Binding sitei798Acetyl-CoABy similarity1

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/function%5Fsection">Function</a> section specifies the position(s) and type(s) of zinc fingers within the protein.<p><a href='/help/zn_fing' target='_top'>More...</a></p>Zinc fingeri571 – 596C2HC MYST-typePROSITE-ProRule annotationAdd BLAST26

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionAcyltransferase, Chromatin regulator, Transferase
LigandMetal-binding, Zinc

Enzyme and pathway databases

Reactome - a knowledgebase of biological pathways and processes

More...
Reactomei
R-DME-3214847 HATs acetylate histones

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Males-absent on the first protein (EC:2.3.1.481 Publication1 Publication)
Alternative name(s):
Histone acetyl transferase MOF
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:mof
ORF Names:CG3025
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiDrosophila melanogaster (Fruit fly)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri7227 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaEcdysozoaArthropodaHexapodaInsectaPterygotaNeopteraHolometabolaDipteraBrachyceraMuscomorphaEphydroideaDrosophilidaeDrosophilaSophophora
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000000803 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome X

Organism-specific databases

Drosophila genome database

More...
FlyBasei
FBgn0014340 mof

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

Keywords - Cellular componenti

Chromosome, Nucleus

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Mutagenesis

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/manual/pathology%5Fand%5Fbiotech%5Fsection">'Pathology and Biotech'</a> section describes the effect of the experimental mutation of one or more amino acid(s) on the biological properties of the protein.<p><a href='/help/mutagen' target='_top'>More...</a></p>Mutagenesisi577C → G: Abolishes histone acetyltransferase activity. 1 Publication1
Mutagenesisi578 – 580LKY → GYG: Nearly abolishes histone acetyltransferase activity. 1 Publication3
Mutagenesisi691G → E: Strongly reduces histone acetyltransferase activity. Males fail to metamorphose and hatch. 2 Publications1

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00000515631 – 827Males-absent on the first proteinAdd BLAST827

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section specifies the position and type of each modified residue excluding <a href="http://www.uniprot.org/manual/lipid">lipids</a>, <a href="http://www.uniprot.org/manual/carbohyd">glycans</a> and <a href="http://www.uniprot.org/manual/crosslnk">protein cross-links</a>.<p><a href='/help/mod_res' target='_top'>More...</a></p>Modified residuei638N6-acetyllysine; by autocatalysisBy similarity1

<p>This subsection of the <a href="http://www.uniprot.org/help/ptm%5Fprocessing%5Fsection">PTM/processing</a> section describes post-translational modifications (PTMs). This subsection <strong>complements</strong> the information provided at the sequence level or describes modifications for which <strong>position-specific data is not yet available</strong>.<p><a href='/help/post-translational_modification' target='_top'>More...</a></p>Post-translational modificationi

Autoacetylation at Lys-638 is required for binding histone H4 with high affinity and for proper function.By similarity

Keywords - PTMi

Acetylation

Proteomic databases

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
O02193

PRoteomics IDEntifications database

More...
PRIDEi
O02193

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
FBgn0014340 Expressed in embryo and 26 other tissues

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
O02193 DM

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the <a href="http://www.uniprot.org/help/interaction%5Fsection">'Interaction'</a> section provides information about the protein quaternary structure and interaction(s) with other proteins or protein complexes (with the exception of physiological receptor-ligand interactions which are annotated in the <a href="http://www.uniprot.org/help/function%5Fsection">'Function'</a> section).<p><a href='/help/subunit_structure' target='_top'>More...</a></p>Subunit structurei

Component of the male-specific lethal (MSL) histone acetyltransferase complex at least composed of mof, msl-1, msl-2 and msl-3 (PubMed:20620954, PubMed:16543150).

Component of the non-specific lethal (NLS) histone acetyltransferase complex at least composed of mof, nls1, dgt1/NSL2, Rcd1/NSL3, Rcd5/MCRS2, MBD-R2 and wds (PubMed:16543150, PubMed:20620954).

2 Publications

<p>This subsection of the '<a href="http://www.uniprot.org/help/interaction%5Fsection%27">Interaction</a> section provides information about binary protein-protein interactions. The data presented in this section are a quality-filtered subset of binary interactions automatically derived from the <a href="http://www.ebi.ac.uk/intact/">IntAct database</a>. It is updated on a monthly basis. Each binary interaction is displayed on a separate line.<p><a href='/help/binary_interactions' target='_top'>More...</a></p>Binary interactionsi

WithEntry#Exp.IntActNotes
A4V2Z14EBI-138539,EBI-9630827

GO - Molecular functioni

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGrid)

More...
BioGridi
58017, 29 interactors

Database of interacting proteins

More...
DIPi
DIP-46346N

Protein interaction database and analysis system

More...
IntActi
O02193, 3 interactors

STRING: functional protein association networks

More...
STRINGi
7227.FBpp0070794

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

Secondary structure

1827
Legend: HelixTurnBeta strandPDB Structure known for this area
Show more details

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
O02193

Database of comparative protein structure models

More...
ModBasei
Search...

Protein Data Bank in Europe - Knowledge Base

More...
PDBe-KBi
Search...

Miscellaneous databases

Relative evolutionary importance of amino acids within a protein sequence

More...
EvolutionaryTracei
O02193

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family%5Fand%5Fdomains%5Fsection">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini538 – 813MYST-type HATPROSITE-ProRule annotationAdd BLAST276

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni370 – 443Chromo barrel domainAdd BLAST74
Regioni681 – 683Acetyl-CoA bindingBy similarity3
Regioni688 – 694Acetyl-CoA bindingBy similarity7

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes the position of regions of compositional bias within the protein and the particular amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi93 – 116Ser-richAdd BLAST24
Compositional biasi135 – 141Poly-Gln7
Compositional biasi212 – 314Pro-richAdd BLAST103
Compositional biasi340 – 346Poly-Glu7
Compositional biasi466 – 472Poly-Ala7

<p>This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the MYST (SAS/MOZ) family.Curated

Zinc finger

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Zinc fingeri571 – 596C2HC MYST-typePROSITE-ProRule annotationAdd BLAST26

Keywords - Domaini

Zinc-finger

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG2747 Eukaryota
COG5027 LUCA

Ensembl GeneTree

More...
GeneTreei
ENSGT00940000159512

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
CLU_012139_1_0_1

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
O02193

KEGG Orthology (KO)

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KOi
K11308

Identification of Orthologs from Complete Genome Data

More...
OMAi
SNTVICV

Database of Orthologous Groups

More...
OrthoDBi
629545at2759

Database for complete collections of gene phylogenies

More...
PhylomeDBi
O02193

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

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Gene3Di
1.10.10.10, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR016181 Acyl_CoA_acyltransferase
IPR016197 Chromo-like_dom_sf
IPR002717 HAT_MYST-type
IPR037906 KAT8
IPR025995 Tudor-knot
IPR036388 WH-like_DNA-bd_sf
IPR040706 Zf-MYST

The PANTHER Classification System

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PANTHERi
PTHR10615:SF82 PTHR10615:SF82, 1 hit

Pfam protein domain database

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Pfami
View protein in Pfam
PF01853 MOZ_SAS, 1 hit
PF11717 Tudor-knot, 1 hit
PF17772 zf-MYST, 1 hit

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF54160 SSF54160, 1 hit
SSF55729 SSF55729, 1 hit

PROSITE; a protein domain and family database

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PROSITEi
View protein in PROSITE
PS51726 MYST_HAT, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

O02193-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MSEAELEQTP SAGHVQEQPI EEEHEPEQEP TDAYTIGGPP RTPVEDAAAE
60 70 80 90 100
LSASLDVSGS DQSAEQSLDL SGVQAEAAAE SEPPAKRQHR DISPISEDST
110 120 130 140 150
PASSTSTSST RSSSSSRYDD VSEAEEAPPE PEPEQPQQQQ QEEKKEDGQD
160 170 180 190 200
QVKSPGPVEL EAQEPAQPQK QKEVVDQEIE TEDEPSSDTV ICVADINPYG
210 220 230 240 250
SGSNIDDFVM DPDAPPNAII TEVVTIPAPL HLKGTQQLGL PLAAPPPPPP
260 270 280 290 300
PPAAEQVPET PASPTDDGEE PPAVYLSPYI RSRYMQESTP GLPTRLAPRD
310 320 330 340 350
PRQRNMPPPA VVLPIQTVLS ANVEAISDDS SETSSSDDDE EEEEDEDDAL
360 370 380 390 400
TMEHDNTSRE TVITTGDPLM QKIDISENPD KIYFIRREDG TVHRGQVLQS
410 420 430 440 450
RTTENAAAPD EYYVHYVGLN RRLDGWVGRH RISDNADDLG GITVLPAPPL
460 470 480 490 500
APDQPSTSRE MLAQQAAAAA AASSERQKRA ANKDYYLSYC ENSRYDYSDR
510 520 530 540 550
KMTRYQKRRY DEINHVQKSH AELTATQAAL EKEHESITKI KYIDKLQFGN
560 570 580 590 600
YEIDTWYFSP FPEEYGKART LYVCEYCLKY MRFRSSYAYH LHECDRRRPP
610 620 630 640 650
GREIYRKGNI SIYEVNGKEE SLYCQLLCLM AKLFLDHKVL YFDMDPFLFY
660 670 680 690 700
ILCETDKEGS HIVGYFSKEK KSLENYNVAC ILVLPPHQRK GFGKLLIAFS
710 720 730 740 750
YELSRKEGVI GSPEKPLSDL GRLSYRSYWA YTLLELMKTR CAPEQITIKE
760 770 780 790 800
LSEMSGITHD DIIYTLQSMK MIKYWKGQNV ICVTSKTIQD HLQLPQFKQP
810 820
KLTIDTDYLV WSPQTAAAVV RAPGNSG
Length:827
Mass (Da):92,657
Last modified:July 1, 1997 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i8B9C5E87E3B01317
GO

Natural variant

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section describes natural variant(s) of the protein sequence.<p><a href='/help/variant' target='_top'>More...</a></p>Natural varianti5E → V in strain: Congo 159, Congo 194 and Congo 216. 1 Publication1
Natural varianti48A → S in strain: Africa-1 and Africa-5. 1 Publication1
Natural varianti119D → E in strain: Congo 216. 1 Publication1
Natural varianti156G → D in strain: Congo 8, Congo 13, Congo 194 and Mof.820A.s. 2 Publications1
Natural varianti202G → C in strain: Africa-0. 1 Publication1
Natural varianti254A → V in strain: Congo 194. 1 Publication1
Natural varianti384F → Y in strain: Africa-0, Africa-3, Africa-4, Congo 194 and Mof.591A.s. 2 Publications1

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

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EMBLi

GenBank nucleotide sequence database

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GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
U71219 Genomic DNA Translation: AAC47507.1
EF630368 Genomic DNA Translation: ABU97211.1
EF630369 Genomic DNA Translation: ABU97212.1
EF630370 Genomic DNA Translation: ABU97213.1
EF630371 Genomic DNA Translation: ABU97214.1
EF630372 Genomic DNA Translation: ABU97215.1
EF630373 Genomic DNA Translation: ABU97216.1
EF630374 Genomic DNA Translation: ABU97217.1
EF630375 Genomic DNA Translation: ABU97218.1
EF630376 Genomic DNA Translation: ABU97219.1
EF630377 Genomic DNA Translation: ABU97220.1
EF630378 Genomic DNA Translation: ABU97221.1
EF630379 Genomic DNA Translation: ABU97222.1
AE014298 Genomic DNA Translation: AAF46095.1
AY102685 mRNA Translation: AAM27514.1
EU167134 Genomic DNA Translation: ABV82526.1
EU167135 Genomic DNA Translation: ABV82527.1
EU167136 Genomic DNA Translation: ABV82528.1
EU167137 Genomic DNA Translation: ABV82529.1
EU167138 Genomic DNA Translation: ABV82530.1
EU167139 Genomic DNA Translation: ABV82531.1
EU167140 Genomic DNA Translation: ABV82532.1
EU167141 Genomic DNA Translation: ABV82533.1

NCBI Reference Sequences

More...
RefSeqi
NP_511051.1, NM_078496.3

Genome annotation databases

Ensembl metazoan genome annotation project

More...
EnsemblMetazoai
FBtr0070829; FBpp0070794; FBgn0014340

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
31518

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
dme:Dmel_CG3025

Keywords - Coding sequence diversityi

Polymorphism

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U71219 Genomic DNA Translation: AAC47507.1
EF630368 Genomic DNA Translation: ABU97211.1
EF630369 Genomic DNA Translation: ABU97212.1
EF630370 Genomic DNA Translation: ABU97213.1
EF630371 Genomic DNA Translation: ABU97214.1
EF630372 Genomic DNA Translation: ABU97215.1
EF630373 Genomic DNA Translation: ABU97216.1
EF630374 Genomic DNA Translation: ABU97217.1
EF630375 Genomic DNA Translation: ABU97218.1
EF630376 Genomic DNA Translation: ABU97219.1
EF630377 Genomic DNA Translation: ABU97220.1
EF630378 Genomic DNA Translation: ABU97221.1
EF630379 Genomic DNA Translation: ABU97222.1
AE014298 Genomic DNA Translation: AAF46095.1
AY102685 mRNA Translation: AAM27514.1
EU167134 Genomic DNA Translation: ABV82526.1
EU167135 Genomic DNA Translation: ABV82527.1
EU167136 Genomic DNA Translation: ABV82528.1
EU167137 Genomic DNA Translation: ABV82529.1
EU167138 Genomic DNA Translation: ABV82530.1
EU167139 Genomic DNA Translation: ABV82531.1
EU167140 Genomic DNA Translation: ABV82532.1
EU167141 Genomic DNA Translation: ABV82533.1
RefSeqiNP_511051.1, NM_078496.3

3D structure databases

Select the link destinations:

Protein Data Bank Europe

More...
PDBei

Protein Data Bank RCSB

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RCSB PDBi

Protein Data Bank Japan

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PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
2BUDNMR-A367-454[»]
SMRiO02193
ModBaseiSearch...
PDBe-KBiSearch...

Protein-protein interaction databases

BioGridi58017, 29 interactors
DIPiDIP-46346N
IntActiO02193, 3 interactors
STRINGi7227.FBpp0070794

Proteomic databases

PaxDbiO02193
PRIDEiO02193

Genome annotation databases

EnsemblMetazoaiFBtr0070829; FBpp0070794; FBgn0014340
GeneIDi31518
KEGGidme:Dmel_CG3025

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
31518
FlyBaseiFBgn0014340 mof

Phylogenomic databases

eggNOGiKOG2747 Eukaryota
COG5027 LUCA
GeneTreeiENSGT00940000159512
HOGENOMiCLU_012139_1_0_1
InParanoidiO02193
KOiK11308
OMAiSNTVICV
OrthoDBi629545at2759
PhylomeDBiO02193

Enzyme and pathway databases

ReactomeiR-DME-3214847 HATs acetylate histones

Miscellaneous databases

EvolutionaryTraceiO02193

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

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GenomeRNAii
31518

Protein Ontology

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PROi
PR:O02193

Gene expression databases

BgeeiFBgn0014340 Expressed in embryo and 26 other tissues
GenevisibleiO02193 DM

Family and domain databases

Gene3Di1.10.10.10, 1 hit
InterProiView protein in InterPro
IPR016181 Acyl_CoA_acyltransferase
IPR016197 Chromo-like_dom_sf
IPR002717 HAT_MYST-type
IPR037906 KAT8
IPR025995 Tudor-knot
IPR036388 WH-like_DNA-bd_sf
IPR040706 Zf-MYST
PANTHERiPTHR10615:SF82 PTHR10615:SF82, 1 hit
PfamiView protein in Pfam
PF01853 MOZ_SAS, 1 hit
PF11717 Tudor-knot, 1 hit
PF17772 zf-MYST, 1 hit
SUPFAMiSSF54160 SSF54160, 1 hit
SSF55729 SSF55729, 1 hit
PROSITEiView protein in PROSITE
PS51726 MYST_HAT, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

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ProtoNeti
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MobiDB: a database of protein disorder and mobility annotations

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MobiDBi
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<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiMOF_DROME
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: O02193
Secondary accession number(s): A8B845
, A8B850, A8B854, A8B859, A8B879, A8B889, A8B895, A8B8A1, A8ILB7, A8ILC1, A8ILC8, A8ILD1, A8ILD6, A8ILE1, A8ILE5, Q9W463
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: July 15, 1998
Last sequence update: July 1, 1997
Last modified: February 26, 2020
This is version 163 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programDrosophila annotation project

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

3D-structure, Reference proteome

Documents

  1. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  2. SIMILARITY comments
    Index of protein domains and families
  3. Drosophila
    Drosophila: entries, gene names and cross-references to FlyBase
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