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Protein

60S ribosomal protein L4

Gene

rpl-4

Organism
Caenorhabditis elegans
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

GO - Biological processi

  • cytoplasmic translation Source: GO_Central
  • determination of adult lifespan Source: WormBase

Keywordsi

Molecular functionRibonucleoprotein, Ribosomal protein

Enzyme and pathway databases

ReactomeiR-CEL-156827 L13a-mediated translational silencing of Ceruloplasmin expression
R-CEL-1799339 SRP-dependent cotranslational protein targeting to membrane
R-CEL-72689 Formation of a pool of free 40S subunits
R-CEL-72706 GTP hydrolysis and joining of the 60S ribosomal subunit
R-CEL-975956 Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)
R-CEL-975957 Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)

Names & Taxonomyi

Protein namesi
Recommended name:
60S ribosomal protein L4
Gene namesi
Name:rpl-4
ORF Names:B0041.4
OrganismiCaenorhabditis elegans
Taxonomic identifieri6239 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaNematodaChromadoreaRhabditidaRhabditoideaRhabditidaePeloderinaeCaenorhabditis
Proteomesi
  • UP000001940 Componenti: Chromosome I

Organism-specific databases

WormBaseiB0041.4 ; CE07669 ; WBGene00004415 ; rpl-4

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Initiator methionineiRemoved1 Publication
ChainiPRO_00001293582 – 34560S ribosomal protein L4Add BLAST344

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Modified residuei2N-acetylalanine1 Publication1

Keywords - PTMi

Acetylation

Proteomic databases

EPDiO02056
PaxDbiO02056
PeptideAtlasiO02056
PRIDEiO02056

PTM databases

iPTMnetiO02056

Expressioni

Gene expression databases

BgeeiWBGene00004415

Interactioni

Protein-protein interaction databases

BioGridi37538, 9 interactors
DIPiDIP-26846N
IntActiO02056, 10 interactors
STRINGi6239.B0041.4.2

Structurei

3D structure databases

ProteinModelPortaliO02056
SMRiO02056
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Phylogenomic databases

eggNOGiKOG1475 Eukaryota
COG0088 LUCA
GeneTreeiENSGT00390000018145
HOGENOMiHOG000107331
InParanoidiO02056
KOiK02930
OMAiGRGKMRN
OrthoDBiEOG091G0A2I
PhylomeDBiO02056

Family and domain databases

Gene3Di3.40.1370.10, 1 hit
InterProiView protein in InterPro
IPR025755 Ribos_L4_C_dom
IPR002136 Ribosomal_L4/L1e
IPR013000 Ribosomal_L4/L1e_euk/arc_CS
IPR023574 Ribosomal_L4_dom_sf
PfamiView protein in Pfam
PF14374 Ribos_L4_asso_C, 1 hit
PF00573 Ribosomal_L4, 1 hit
SUPFAMiSSF52166 SSF52166, 1 hit
PROSITEiView protein in PROSITE
PS00939 RIBOSOMAL_L1E, 1 hit

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

O02056-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAARPLVTVY DEKYEATQSQ IRLPAVFRTP IRPDLVSFIA DQVRRNRRQA
60 70 80 90 100
HAVNTKAGKQ HSAESWGTGR AVARIPRVRG GGTHRSGQGA FGNMCRGGHM
110 120 130 140 150
FAPLKVFRRW HRNVNIAQKR YAVSSAIAAS GIPALLQARG HVIDQVAEVP
160 170 180 190 200
LVVSDKVESF RKTKEAVVFL RRSHLWADIE KVYNSKRNRA GKGKLRNRQH
210 220 230 240 250
KQKLGPVVIY GQDAECARAF RNIPGVDVMN VERLNLLKLA PGGHLGRLII
260 270 280 290 300
WTESAFKKLD TIYGTTVANS SQLKKGWSVP LPIMANSDFS RIIRSEEVVK
310 320 330 340
AIRAPKKNPV LPKVHRNPLK KRTLLYKLNP YASILRKASK ANVKK
Length:345
Mass (Da):38,659
Last modified:January 23, 2007 - v3
Checksum:iC798B9DB0CED60AD
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
FO080106 Genomic DNA Translation: CCD61249.1
PIRiT34031
RefSeqiNP_491416.1, NM_059015.4
UniGeneiCel.5071

Genome annotation databases

EnsemblMetazoaiB0041.4; B0041.4; WBGene00004415
GeneIDi172074
KEGGicel:CELE_B0041.4
UCSCiB0041.4.1 c. elegans

Similar proteinsi

Entry informationi

Entry nameiRL4_CAEEL
AccessioniPrimary (citable) accession number: O02056
Entry historyiIntegrated into UniProtKB/Swiss-Prot: December 15, 1998
Last sequence update: January 23, 2007
Last modified: July 18, 2018
This is version 128 of the entry and version 3 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programCaenorhabditis annotation project

Miscellaneousi

Keywords - Technical termi

Complete proteome, Direct protein sequencing, Reference proteome

Documents

  1. Caenorhabditis elegans
    Caenorhabditis elegans: entries, gene names and cross-references to WormBase
  2. Ribosomal proteins
    Ribosomal proteins families and list of entries
  3. SIMILARITY comments
    Index of protein domains and families

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