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Entry version 156 (18 Sep 2019)
Sequence version 4 (05 Feb 2008)
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Protein

Structural maintenance of chromosomes protein 1

Gene

him-1

Organism
Caenorhabditis elegans
Status
Reviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Involved in chromosome cohesion during cell cycle and in DNA repair (By similarity). Required for chromosome segregation during mitosis (PubMed:12808038, PubMed:12827206). Central component of cohesin complex (PubMed:12827206). The cohesin complex is required for the cohesion of sister chromatids after DNA replication (PubMed:12827206). The cohesin complex apparently forms a large proteinaceous ring within which sister chromatids can be trapped (By similarity). At anaphase, the complex is cleaved and dissociates from chromatin, allowing sister chromatids to segregate (By similarity).By similarity2 Publications

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

  • ATP binding Source: InterPro
  • DNA binding Source: WormBase

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Biological processCell cycle, Cell division, DNA damage, DNA repair, Mitosis

Enzyme and pathway databases

Reactome - a knowledgebase of biological pathways and processes

More...
Reactomei
R-CEL-2468052 Establishment of Sister Chromatid Cohesion
R-CEL-2470946 Cohesin Loading onto Chromatin
R-CEL-2500257 Resolution of Sister Chromatid Cohesion
R-CEL-3108214 SUMOylation of DNA damage response and repair proteins

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Structural maintenance of chromosomes protein 1Imported
Alternative name(s):
High incidence of males protein 1Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:him-1Imported
Synonyms:smc-1Imported
ORF Names:F28B3.7Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiCaenorhabditis elegansImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri6239 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaEcdysozoaNematodaChromadoreaRhabditidaRhabditinaRhabditomorphaRhabditoideaRhabditidaePeloderinaeCaenorhabditis
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000001940 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome I

Organism-specific databases

WormBase

More...
WormBasei
F28B3.7a ; CE42002 ; WBGene00001860 ; him-1
F28B3.7b ; CE39925 ; WBGene00001860 ; him-1

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

Keywords - Cellular componenti

Chromosome, Nucleus

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

<p>This subsection of the ‘Pathology and Biotech’ section describes the in vivo effects caused by ablation of the gene (or one or more transcripts) coding for the protein described in the entry. This includes gene knockout and knockdown, provided experiments have been performed in the context of a whole organism or a specific tissue, and not at the single-cell level.<p><a href='/help/disruption_phenotype' target='_top'>More...</a></p>Disruption phenotypei

Defective chromosome segregation during germline mitosis, resulting in aneuploidy (PubMed:12827206). RNAi-mediated knock-down is embryonic lethal and results in aberrant chromosome segregation in mitosis (PubMed:12827206, PubMed:12808038).2 Publications

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00004328341 – 1262Structural maintenance of chromosomes protein 1CuratedAdd BLAST1262

Proteomic databases

Encyclopedia of Proteome Dynamics

More...
EPDi
O01789

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
O01789

PeptideAtlas

More...
PeptideAtlasi
O01789

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
WBGene00001860 Expressed in 5 organ(s), highest expression level in germ line (C elegans)

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the <a href="http://www.uniprot.org/help/interaction_section">'Interaction'</a> section provides information about the protein quaternary structure and interaction(s) with other proteins or protein complexes (with the exception of physiological receptor-ligand interactions which are annotated in the <a href="http://www.uniprot.org/help/function_section">'Function'</a> section).<p><a href='/help/subunit_structure' target='_top'>More...</a></p>Subunit structurei

Component of the cohesin complex, composed of the smc-1 and smc-3 heterodimer attached via their SMC hinge domain, scc-1 which links them, and scc-3.

Interacts with smc-3, scc-1, scc-3 and tim-1.

1 Publication

Protein-protein interaction databases

ComplexPortal: manually curated resource of macromolecular complexes

More...
ComplexPortali
CPX-967 Nuclear mitotic cohesin complex

STRING: functional protein association networks

More...
STRINGi
6239.F28B3.7a

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
O01789

Database of comparative protein structure models

More...
ModBasei
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family_and_domains_section">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini524 – 642SMC hingeAdd BLAST119

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and domains’ section denotes the positions of regions of coiled coil within the protein.<p><a href='/help/coiled' target='_top'>More...</a></p>Coiled coili171 – 497Sequence analysisAdd BLAST327
Coiled coili680 – 937Sequence analysisAdd BLAST258
Coiled coili1017 – 1086Sequence analysisAdd BLAST70

Motif

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section describes a short (usually not more than 20 amino acids) conserved sequence motif of biological significance.<p><a href='/help/motif' target='_top'>More...</a></p>Motifi1148 – 1183DA-boxBy similarityAdd BLAST36

<p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the SMC family. SMC1 subfamily.Curated

Keywords - Domaini

Coiled coil

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG0018 Eukaryota
COG1196 LUCA

Ensembl GeneTree

More...
GeneTreei
ENSGT00940000171089

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
HOG000195481

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
O01789

KEGG Orthology (KO)

More...
KOi
K06636

Identification of Orthologs from Complete Genome Data

More...
OMAi
YMEAIVV

Database of Orthologous Groups

More...
OrthoDBi
326079at2759

Database for complete collections of gene phylogenies

More...
PhylomeDBi
O01789

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR027417 P-loop_NTPase
IPR003395 RecF/RecN/SMC_N
IPR024704 SMC
IPR010935 SMC_hinge
IPR036277 SMC_hinge_sf

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF06470 SMC_hinge, 1 hit
PF02463 SMC_N, 1 hit

PIRSF; a whole-protein classification database

More...
PIRSFi
PIRSF005719 SMC, 1 hit

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00968 SMC_hinge, 1 hit

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF52540 SSF52540, 1 hit
SSF75553 SSF75553, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequences (2)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry describes 2 <p>This subsection of the ‘Sequence’ section lists the alternative protein sequences (isoforms) that can be generated from the same gene by a single or by the combination of up to four biological events (alternative promoter usage, alternative splicing, alternative initiation and ribosomal frameshifting). Additionally, this section gives relevant information on each alternative protein isoform.<p><a href='/help/alternative_products' target='_top'>More...</a></p> isoformsi produced by alternative splicing. AlignAdd to basket
Isoform aImported (identifier: O01789-1) [UniParc]FASTAAdd to basket

This isoform has been chosen as the <div> <p><b>What is the canonical sequence?</b><p><a href='/help/canonical_and_isoforms' target='_top'>More...</a></p>canonicali sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide
        10         20         30         40         50
MRGGSSLDSF PGKGTLHTLE IENFKSYKGK HTIGPFTRFT AIIGPNGSGK
60 70 80 90 100
SNLMDAISFV LGEKPSSLRV RKYADLIHGA PINKPVAKKC RVTMNYKYSD
110 120 130 140 150
GKVKAFTRGV NNGTSEHLLD GQTVTSAAYS QEMESINIFI KARNFLVYQG
160 170 180 190 200
AIENIAMKTP KERTQLFEEL SRSHEFQAEY ERLKVEMTKA EDDTQHNMNK
210 220 230 240 250
RRGIAQEKRE AKMEKDEAEK YQTMKNELAA KSTMLFLHQL FHCERTIDES
260 270 280 290 300
KEEINAQKKT IASLEATRSK EEAKIAAVHQ EHRKALREVQ KMTRKLDQKE
310 320 330 340 350
TDLAEKQQNM LTLKVSVAHE HKKLEIAKKM LAAAESKAEN NSTQLADLKK
360 370 380 390 400
SKKELEKKKA AYEAEIQDMM QRGELNLSDE QVREYGQLKD QAQRESAMVQ
410 420 430 440 450
RELLMAEQVF EGDKSSLNHE LRRQKEHQER VKAKEGDVRR IETQIATLAQ
460 470 480 490 500
RIKETEEETK ILKADLKKIE NDVVIDKSAA AEYNKELVAV VRQLSEASGD
510 520 530 540 550
SAEGERNQRR TEALEGLKKN FPESVYGRLV DLCQPSHKRF NIATTKILQK
560 570 580 590 600
HMNSIVCDTE ETAAKAIVYL KDHRYPPETF LPNDALVVNP LNEKLREIKK
610 620 630 640 650
PAGVKLVFDV INPQHQAARK ALQFVCGNAL VCESQEDAKQ LAYGGGELKD
660 670 680 690 700
RFKAVSMDGT LFQQSGVMSG GSADLRQKSK KWDEKVVKQL REKRNQLNEK
710 720 730 740 750
IADLQKHRRR ELEVESVRSK INGNEQRLAM MKRDLKNMRE MQLERLQNEL
760 770 780 790 800
EGMTAEMNML PPRISNCQEK LERSESTLKS LQTKSNEVAD RIFADFCTRV
810 820 830 840 850
GIASIRDYEN REMRIKQEME DKLRSFDDDI QKLAYEIDFV TEQDGNRKVE
860 870 880 890 900
VEKEKVSQID RQYKDMKKKE KTAAAALKEH TESMEQDKEV LEEKKALSHK
910 920 930 940 950
LETEWNEVKK IAQVAMKDFT KAEKELLRLE SLLTKKQYER HSLLHSVKLG
960 970 980 990 1000
QIALPLKSGS MADVEYEEDD GDDTASQSSQ SATDGPSVSE EQIQREQHIK
1010 1020 1030 1040 1050
INYDSLPREY KDVDDDDGVR QMSNRLNVEI DELQKNVSKM NAPNLKANQR
1060 1070 1080 1090 1100
MAEVKEREAE STEELENARK KAKRIRQQFE KVKTDRYRRF QDFFDPVANT
1110 1120 1130 1140 1150
IDDIYKQLSR NTSAQAFLGA DNMEEPYLDG IQYNCVAPGK RFRPMDNLSG
1160 1170 1180 1190 1200
GEKTIAALAL LFAVHGRNPA PFFVLDEIDA ALDNTNIGKV ASYICESARE
1210 1220 1230 1240 1250
HMQIIVISLK EEFYNKADSL IGIFPYPAAC TTSGVLTFDL TRFKQIGLNE
1260
MTENPPTPSI AT
Length:1,262
Mass (Da):144,217
Last modified:February 5, 2008 - v4
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i8473653CC05DB70A
GO
Isoform bImported (identifier: O01789-2) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     1-1122: Missing.

Note: No experimental confirmation available.Curated
Show »
Length:140
Mass (Da):15,374
Checksum:i7754A4C7953ABFF7
GO

Alternative sequence

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section describes the sequence of naturally occurring alternative protein isoform(s). The changes in the amino acid sequence may be due to alternative splicing, alternative promoter usage, alternative initiation, or ribosomal frameshifting.<p><a href='/help/var_seq' target='_top'>More...</a></p>Alternative sequenceiVSP_0575891 – 1122Missing in isoform b. CuratedAdd BLAST1122

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
FO081198 Genomic DNA Translation: CCD69832.1
FO081198 Genomic DNA Translation: CCD69826.1

NCBI Reference Sequences

More...
RefSeqi
NP_001040658.2, NM_001047193.4 [O01789-1]
NP_001040659.1, NM_001047194.1 [O01789-2]

Genome annotation databases

Ensembl metazoan genome annotation project

More...
EnsemblMetazoai
F28B3.7a.1; F28B3.7a.1; WBGene00001860 [O01789-1]
F28B3.7b.1; F28B3.7b.1; WBGene00001860 [O01789-2]

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
172116

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
cel:CELE_F28B3.7

UCSC genome browser

More...
UCSCi
F28B3.7a.1 c. elegans

Keywords - Coding sequence diversityi

Alternative splicing

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
FO081198 Genomic DNA Translation: CCD69832.1
FO081198 Genomic DNA Translation: CCD69826.1
RefSeqiNP_001040658.2, NM_001047193.4 [O01789-1]
NP_001040659.1, NM_001047194.1 [O01789-2]

3D structure databases

SMRiO01789
ModBaseiSearch...

Protein-protein interaction databases

ComplexPortaliCPX-967 Nuclear mitotic cohesin complex
STRINGi6239.F28B3.7a

Proteomic databases

EPDiO01789
PaxDbiO01789
PeptideAtlasiO01789

Genome annotation databases

EnsemblMetazoaiF28B3.7a.1; F28B3.7a.1; WBGene00001860 [O01789-1]
F28B3.7b.1; F28B3.7b.1; WBGene00001860 [O01789-2]
GeneIDi172116
KEGGicel:CELE_F28B3.7
UCSCiF28B3.7a.1 c. elegans

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
172116
WormBaseiF28B3.7a ; CE42002 ; WBGene00001860 ; him-1
F28B3.7b ; CE39925 ; WBGene00001860 ; him-1

Phylogenomic databases

eggNOGiKOG0018 Eukaryota
COG1196 LUCA
GeneTreeiENSGT00940000171089
HOGENOMiHOG000195481
InParanoidiO01789
KOiK06636
OMAiYMEAIVV
OrthoDBi326079at2759
PhylomeDBiO01789

Enzyme and pathway databases

ReactomeiR-CEL-2468052 Establishment of Sister Chromatid Cohesion
R-CEL-2470946 Cohesin Loading onto Chromatin
R-CEL-2500257 Resolution of Sister Chromatid Cohesion
R-CEL-3108214 SUMOylation of DNA damage response and repair proteins

Miscellaneous databases

Protein Ontology

More...
PROi
PR:O01789

Gene expression databases

BgeeiWBGene00001860 Expressed in 5 organ(s), highest expression level in germ line (C elegans)

Family and domain databases

InterProiView protein in InterPro
IPR027417 P-loop_NTPase
IPR003395 RecF/RecN/SMC_N
IPR024704 SMC
IPR010935 SMC_hinge
IPR036277 SMC_hinge_sf
PfamiView protein in Pfam
PF06470 SMC_hinge, 1 hit
PF02463 SMC_N, 1 hit
PIRSFiPIRSF005719 SMC, 1 hit
SMARTiView protein in SMART
SM00968 SMC_hinge, 1 hit
SUPFAMiSSF52540 SSF52540, 1 hit
SSF75553 SSF75553, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiSMC1_CAEEL
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: O01789
Secondary accession number(s): Q2A957
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: April 29, 2015
Last sequence update: February 5, 2008
Last modified: September 18, 2019
This is version 156 of the entry and version 4 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programCaenorhabditis annotation project

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
  2. Caenorhabditis elegans
    Caenorhabditis elegans: entries, gene names and cross-references to WormBase
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