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Entry version 122 (17 Jun 2020)
Sequence version 2 (01 Oct 2001)
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Protein
Submitted name:

Spliceosome Associated Rna (RNA) binding facTor

Gene

sart-1

Organism
Caenorhabditis elegans
Status
Unreviewed-Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Biological processi

Enzyme and pathway databases

Reactome - a knowledgebase of biological pathways and processes

More...
Reactomei
R-CEL-72163 mRNA Splicing - Major Pathway

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Submitted name:
Spliceosome Associated Rna (RNA) binding facTorImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:sart-1Imported
ORF Names:CELE_F19F10.9Imported, F19F10.9Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiCaenorhabditis elegansImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri6239 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaEcdysozoaNematodaChromadoreaRhabditidaRhabditinaRhabditomorphaRhabditoideaRhabditidaePeloderinaeCaenorhabditis
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000001940 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome V

Organism-specific databases

WormBase

More...
WormBasei
F19F10.9 ; CE27372 ; WBGene00017605 ; sart-1

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Proteomic databases

Encyclopedia of Proteome Dynamics

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EPDi
O01524

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
O01524

PeptideAtlas

More...
PeptideAtlasi
O01524

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
WBGene00017605 Expressed in material anatomical entity and 4 other tissues

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

STRING: functional protein association networks

More...
STRINGi
6239.F19F10.9

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

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SMRi
O01524

Database of comparative protein structure models

More...
ModBasei
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni1 – 92DisorderedSequence analysisAdd BLAST92
Regioni141 – 162DisorderedSequence analysisAdd BLAST22
Regioni367 – 430DisorderedSequence analysisAdd BLAST64
Regioni566 – 659DisorderedSequence analysisAdd BLAST94
Regioni674 – 733DisorderedSequence analysisAdd BLAST60
Regioni763 – 829DisorderedSequence analysisAdd BLAST67

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes the position of regions of compositional bias within the protein and the particular amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi1 – 22PolyampholyteSequence analysisAdd BLAST22
Compositional biasi72 – 92PolyampholyteSequence analysisAdd BLAST21
Compositional biasi367 – 422PolyampholyteSequence analysisAdd BLAST56
Compositional biasi566 – 601PolyampholyteSequence analysisAdd BLAST36
Compositional biasi614 – 635PolyampholyteSequence analysisAdd BLAST22
Compositional biasi676 – 693PolarSequence analysisAdd BLAST18
Compositional biasi694 – 720PolyampholyteSequence analysisAdd BLAST27
Compositional biasi763 – 790PolyampholyteSequence analysisAdd BLAST28

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG2217 Eukaryota
ENOG410XSTT LUCA

Ensembl GeneTree

More...
GeneTreei
ENSGT00390000007071

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
CLU_009379_3_0_1

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
O01524

KEGG Orthology (KO)

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KOi
K11984

Identification of Orthologs from Complete Genome Data

More...
OMAi
ARWENKQ

Database of Orthologous Groups

More...
OrthoDBi
1068640at2759

Database for complete collections of gene phylogenies

More...
PhylomeDBi
O01524

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR005011 SNU66/SART1

The PANTHER Classification System

More...
PANTHERi
PTHR14152 PTHR14152, 1 hit

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF03343 SART-1, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

O01524-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MSSKYSKKRK QFDDDTSEVG KNRDSSRSPS PPRSKRSAKQ REPEDNGEPA
60 70 80 90 100
DSMSIEETNK LRASLGLAPL ETNDNKERDA NDGTNEKIYN EDGFEFRHRK
110 120 130 140 150
AENISDKKKE KDIKEKLEIA KAKRDVYSKV LKAKKLADSD EEDSAASFVN
160 170 180 190 200
KMRQKEDEAK KAADRAAAFD QLDEELGVSA IVDKVKKPKK PKTKGPSDTA
210 220 230 240 250
GMVIGHGREA FIEGDQILVL QDKGVLDDGD EVLVNPNLLD NERHVRNVEL
260 270 280 290 300
RKRKDPNRNF DEDVDEFGNA KNFGVLAKYD ETLEGEQKKQ FRLDEHGGVD
310 320 330 340 350
LEEERREMEA FRRMKMAGKR LESLETKKYE LASEFYTQDE MTQFRKVKKG
360 370 380 390 400
KKEKNIRKRK VLKASDLVPV EKAGEGRDFG RRRRDSDEPE DEGLKKEKQD
410 420 430 440 450
GKDEDGEISD KEVPESSSDN GKWKKAMRGN GVDLQRLQKL RSKHQIAEDD
460 470 480 490 500
DSDNDLMFSG GVDLTGVVID DNAEEELSSI LAKTRKVKQI DGKQMDNDVG
510 520 530 540 550
KKVQDILTSH GVKMEIDEEE DVKPLKEGQI YIDSTTEYCR HVGEITTLGL
560 570 580 590 600
GGNRTVDVSE VKKVKEEEME QEGSEGFEKW KRAKVDKELK EKEKRKLRDQ
610 620 630 640 650
GGWLAAGEPA PSNARIDSDD EDALEEAKKR KWSEDEEEDE DMEEDKDDYA
660 670 680 690 700
PALGQEVDVS KGVGRMLKLA GQKGYLQNPN AKSHSGPSLD HLKNKTTQRI
710 720 730 740 750
DGQRFDPDDR NAKKADRLNS QHRGPVMPFA EKHDYKPDVN ISYVDRKGRE
760 770 780 790 800
MDAKDAYREL SYKFHGRNPG KKQLEKRANR KDKEERMLKT NSYDTPLGTL
810 820
DKQRKKQKQL STPYLVLSGS SDHSSLKKE
Length:829
Mass (Da):94,493
Last modified:October 1, 2001 - v2
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i5525E4DE4553CD54
GO

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

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EMBLi

GenBank nucleotide sequence database

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GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
BX284605 Genomic DNA Translation: CCD67759.1

NCBI Reference Sequences

More...
RefSeqi
NP_504952.1, NM_072551.4

Genome annotation databases

Ensembl metazoan genome annotation project

More...
EnsemblMetazoai
F19F10.9.1; F19F10.9.1; WBGene00017605

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
179140

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
cel:CELE_F19F10.9

UCSC genome browser

More...
UCSCi
F19F10.9 c. elegans

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BX284605 Genomic DNA Translation: CCD67759.1
RefSeqiNP_504952.1, NM_072551.4

3D structure databases

SMRiO01524
ModBaseiSearch...

Protein-protein interaction databases

STRINGi6239.F19F10.9

Proteomic databases

EPDiO01524
PaxDbiO01524
PeptideAtlasiO01524

Genome annotation databases

EnsemblMetazoaiF19F10.9.1; F19F10.9.1; WBGene00017605
GeneIDi179140
KEGGicel:CELE_F19F10.9
UCSCiF19F10.9 c. elegans

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
179140
WormBaseiF19F10.9 ; CE27372 ; WBGene00017605 ; sart-1

Phylogenomic databases

eggNOGiKOG2217 Eukaryota
ENOG410XSTT LUCA
GeneTreeiENSGT00390000007071
HOGENOMiCLU_009379_3_0_1
InParanoidiO01524
KOiK11984
OMAiARWENKQ
OrthoDBi1068640at2759
PhylomeDBiO01524

Enzyme and pathway databases

ReactomeiR-CEL-72163 mRNA Splicing - Major Pathway

Gene expression databases

BgeeiWBGene00017605 Expressed in material anatomical entity and 4 other tissues

Family and domain databases

InterProiView protein in InterPro
IPR005011 SNU66/SART1
PANTHERiPTHR14152 PTHR14152, 1 hit
PfamiView protein in Pfam
PF03343 SART-1, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiO01524_CAEEL
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: O01524
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: July 1, 1997
Last sequence update: October 1, 2001
Last modified: June 17, 2020
This is version 122 of the entry and version 2 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Technical termi

Proteomics identificationCombined sources, Reference proteomeImported
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