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Entry version 156 (07 Apr 2021)
Sequence version 1 (01 Jul 1997)
Previous versions | rss
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Protein

Histone acetyltransferase

Gene

nej

Organism
Drosophila melanogaster (Fruit fly)
Status
Unreviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Acetyltransferase enzyme. Acetylates histones, giving a specific tag for transcriptional activation.ARBA annotation

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/function%5Fsection">Function</a> section describes the interaction between a single amino acid and another chemical entity. Priority is given to the annotation of physiological ligands.<p><a href='/help/binding' target='_top'>More...</a></p>Binding sitei2114Acetyl-CoA; via carbonyl oxygenPROSITE-ProRule annotation1
Binding sitei2119Acetyl-CoAPROSITE-ProRule annotation1
Binding sitei2123Acetyl-CoAPROSITE-ProRule annotation1

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/function%5Fsection">Function</a> section specifies the position(s) and type(s) of zinc fingers within the protein.<p><a href='/help/zn_fing' target='_top'>More...</a></p>Zinc fingeri508 – 594TAZ-typePROSITE-ProRule annotationAdd BLAST87
Zinc fingeri2392 – 2473TAZ-typePROSITE-ProRule annotationAdd BLAST82

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionAcyltransferasePROSITE-ProRule annotationARBA annotation, Transferase
Biological processTranscription, Transcription regulationARBA annotation
LigandMetal-binding, Zinc

Enzyme and pathway databases

SignaLink: a signaling pathway resource with multi-layered regulatory networks

More...
SignaLinki
O01368

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Histone acetyltransferaseARBA annotation (EC:2.3.1.48ARBA annotation)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:nejImported
ORF Names:CG15319Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiDrosophila melanogaster (Fruit fly)Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri7227 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaEcdysozoaArthropodaHexapodaInsectaPterygotaNeopteraHolometabolaDipteraBrachyceraMuscomorphaEphydroideaDrosophilidaeDrosophilaSophophora

Organism-specific databases

Drosophila genome database

More...
FlyBasei
FBgn0261617, nej

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Keywords - Cellular componenti

NucleusARBA annotation

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Keywords - PTMi

MethylationARBA annotation

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
FBgn0261617, Expressed in female gonad and 33 other tissues

ExpressionAtlas, Differential and Baseline Expression

More...
ExpressionAtlasi
O01368, baseline and differential

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the '<a href="http://www.uniprot.org/help/interaction%5Fsection">Interaction</a>' section provides information about binary protein-protein interactions. The data presented in this section are a quality-filtered subset of binary interactions automatically derived from the <a href="https://www.ebi.ac.uk/intact/">IntAct database</a>. It is updated at every <a href="http://www.uniprot.org/help/synchronization">UniProt release</a>.<p><a href='/help/binary_interactions' target='_top'>More...</a></p>Binary interactionsi

Hide details

GO - Molecular functioni

Protein-protein interaction databases

Database of interacting proteins

More...
DIPi
DIP-41329N

Protein interaction database and analysis system

More...
IntActi
O01368, 2 interactors

Molecular INTeraction database

More...
MINTi
O01368

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family%5Fand%5Fdomains%5Fsection">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini508 – 594TAZ-typeInterPro annotationAdd BLAST87
Domaini938 – 1017KIXInterPro annotationAdd BLAST80
Domaini1715 – 1787BromoInterPro annotationAdd BLAST73
Domaini1945 – 2328CBP/p300-type HATInterPro annotationAdd BLAST384
Domaini2329 – 2372ZZ-typeInterPro annotationAdd BLAST44
Domaini2392 – 2473TAZ-typeInterPro annotationAdd BLAST82

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni33 – 87DisorderedSequence analysisAdd BLAST55
Regioni111 – 156DisorderedSequence analysisAdd BLAST46
Regioni307 – 465DisorderedSequence analysisAdd BLAST159
Regioni611 – 707DisorderedSequence analysisAdd BLAST97
Regioni759 – 833DisorderedSequence analysisAdd BLAST75
Regioni868 – 943DisorderedSequence analysisAdd BLAST76
Regioni1064 – 1113DisorderedSequence analysisAdd BLAST50
Regioni1143 – 1184DisorderedSequence analysisAdd BLAST42
Regioni1224 – 1599DisorderedSequence analysisAdd BLAST376
Regioni1630 – 1695DisorderedSequence analysisAdd BLAST66
Regioni2055 – 2057Acetyl-CoA bindingPROSITE-ProRule annotation3
Regioni2067 – 2068Acetyl-CoA bindingPROSITE-ProRule annotation2
Regioni2205 – 2244DisorderedSequence analysisAdd BLAST40
Regioni2680 – 2735DisorderedSequence analysisAdd BLAST56
Regioni2855 – 2957DisorderedSequence analysisAdd BLAST103
Regioni2999 – 3028DisorderedSequence analysisAdd BLAST30

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and domains' section denotes the positions of regions of coiled coil within the protein.<p><a href='/help/coiled' target='_top'>More...</a></p>Coiled coili2170 – 2197Sequence analysisAdd BLAST28

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes the position of regions of compositional bias within the protein and the particular amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi112 – 156PolarSequence analysisAdd BLAST45
Compositional biasi330 – 344PolarSequence analysisAdd BLAST15
Compositional biasi353 – 374PolarSequence analysisAdd BLAST22
Compositional biasi410 – 433PolarSequence analysisAdd BLAST24
Compositional biasi440 – 465PolarSequence analysisAdd BLAST26
Compositional biasi633 – 660PolarSequence analysisAdd BLAST28
Compositional biasi667 – 681PolarSequence analysisAdd BLAST15
Compositional biasi775 – 828PolarSequence analysisAdd BLAST54
Compositional biasi899 – 917PolarSequence analysisAdd BLAST19
Compositional biasi1064 – 1085PolarSequence analysisAdd BLAST22
Compositional biasi1143 – 1161PolarSequence analysisAdd BLAST19
Compositional biasi1224 – 1308PolarSequence analysisAdd BLAST85
Compositional biasi1320 – 1376PolarSequence analysisAdd BLAST57
Compositional biasi1392 – 1459PolarSequence analysisAdd BLAST68
Compositional biasi1467 – 1481PolarSequence analysisAdd BLAST15
Compositional biasi1489 – 1518PolarSequence analysisAdd BLAST30
Compositional biasi1533 – 1547PolarSequence analysisAdd BLAST15
Compositional biasi1557 – 1574PolyampholyteSequence analysisAdd BLAST18
Compositional biasi1575 – 1599PolarSequence analysisAdd BLAST25
Compositional biasi2214 – 2230BasicSequence analysisAdd BLAST17
Compositional biasi2721 – 2735PolarSequence analysisAdd BLAST15
Compositional biasi2872 – 2942PolarSequence analysisAdd BLAST71

Zinc finger

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Zinc fingeri508 – 594TAZ-typePROSITE-ProRule annotationAdd BLAST87
Zinc fingeri2392 – 2473TAZ-typePROSITE-ProRule annotationAdd BLAST82

Keywords - Domaini

BromodomainPROSITE-ProRule annotationARBA annotation, Coiled coilSequence analysis, Zinc-fingerPROSITE-ProRule annotationARBA annotation

Phylogenomic databases

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
CLU_000162_0_0_1

Family and domain databases

Conserved Domains Database

More...
CDDi
cd15802, RING_CBP-p300, 1 hit

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
1.10.246.20, 1 hit
1.20.1020.10, 2 hits
1.20.920.10, 1 hit
2.10.110.40, 1 hit
3.30.40.10, 1 hit
3.30.60.90, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR001487, Bromodomain
IPR036427, Bromodomain-like_sf
IPR018359, Bromodomain_CS
IPR031162, CBP_P300_HAT
IPR013178, Histone_AcTrfase_Rtt109/CBP
IPR003101, KIX_dom
IPR036529, KIX_dom_sf
IPR010303, RING_CBP-p300
IPR038547, RING_CBP-p300_sf
IPR035898, TAZ_dom_sf
IPR019786, Zinc_finger_PHD-type_CS
IPR013083, Znf_RING/FYVE/PHD
IPR000197, Znf_TAZ
IPR000433, Znf_ZZ
IPR043145, Znf_ZZ_sf

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF00439, Bromodomain, 1 hit
PF06001, DUF902, 1 hit
PF08214, HAT_KAT11, 1 hit
PF02172, KIX, 1 hit
PF02135, zf-TAZ, 2 hits
PF00569, ZZ, 1 hit

Protein Motif fingerprint database; a protein domain database

More...
PRINTSi
PR00503, BROMODOMAIN

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00297, BROMO, 1 hit
SM01250, KAT11, 1 hit
SM00551, ZnF_TAZ, 2 hits
SM00291, ZnF_ZZ, 1 hit

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF47040, SSF47040, 1 hit
SSF47370, SSF47370, 1 hit
SSF57933, SSF57933, 2 hits

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS00633, BROMODOMAIN_1, 1 hit
PS50014, BROMODOMAIN_2, 1 hit
PS51727, CBP_P300_HAT, 1 hit
PS50952, KIX, 1 hit
PS01359, ZF_PHD_1, 1 hit
PS50134, ZF_TAZ, 2 hits
PS01357, ZF_ZZ_1, 1 hit
PS50135, ZF_ZZ_2, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

O01368-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MMADHLDEPP QKRVKMDPTD ISYFLEENLP DELVSSNSGW SDQLTGGAGG
60 70 80 90 100
GNGGGGASGV TTNPTSGPNP GGGPNKPAAQ GPGSGTGGVG VGVNVGVGGV
110 120 130 140 150
VGVGVVPSQM NGAGGGNGSG TGGDDGSGNG SGAGNRISQM QHQQLQHLLQ
160 170 180 190 200
QQQQGQKGAM VVPGMQQLGS KSPNLQSPNQ GGMQQVVGTQ MGMVNSMPMS
210 220 230 240 250
ISNNGNNGMN AIPGMNTIAQ GNLGNMVLTN SVGGGMGGMV NHLKQQPGGG
260 270 280 290 300
GGGMINSVSV PGGPGAGAGG VGAGGGGAVA ANQGMHMQNG PMMGRMVGQQ
310 320 330 340 350
HMLRGPHLMG ASGGAGGPGN GPGGGGPRMQ NPNMQMTQLN SLPYGVGQYG
360 370 380 390 400
GPGGGNNPQQ QQQQQQQQLL AQQMAQRGGV VPGMPRGNRP VGTVVPMSTL
410 420 430 440 450
GGDGSGPAGQ LVSGNPQQQQ MLAQQQTGAM GPRPPQPNQL LGHPGQQQQQ
460 470 480 490 500
QQQPGTSQQQ QQQQGVGIGG AGVVANAGTV AGVPAVAGGG AGGAVQSSGP
510 520 530 540 550
GGANRDVPDD RKRQIQQQLM LLLHAHKCNR RENLNPNREV CNVNYCKAMK
560 570 580 590 600
SVLAHMGTCK QSKDCTMQHC ASSRQILLHY KTCQNSGCVI CYPFRQNHSV
610 620 630 640 650
FQNANVPPGG GPAGIGGAPP GGGGAGGGAA GAGGNLQQQQ QQQQQQQQNQ
660 670 680 690 700
QPNLTGLVVG GKQGQQVAPG GGQNTAIVLP QQQGAGGAPG APKTPADMVQ
710 720 730 740 750
QLTQQQQQQQ QQVHQQQVQQ QELRRFDGMS QQVVAGGMQQ QQQQGLPPVI
760 770 780 790 800
RIQGAQPAVR VLGPGGPGGP SGPNVLPNDV NSLHQQQQQM LQQQQQQGQN
810 820 830 840 850
RRRGGLATMV EQQQQHQQQQ QQPNPAQLGG NIPAPLSVNV GGFGNTNFGG
860 870 880 890 900
AAAGGAVGAN DKQQLKVAQV HPQSHGVGAG GASAGAGASG GQVAAGSSVL
910 920 930 940 950
MPADTTGSGN AGNPNQNAGG VAGGAGGGNG GNTGPPGDNE KDWRESVTAD
960 970 980 990 1000
LRNHLVHKLV QAIFPTSDPT TMQDKRMHNL VSYAEKVEKD MYEMAKSRSE
1010 1020 1030 1040 1050
YYHLLAEKIY KIQKELEEKR LKRKEQHQQM LMQQQGVANP VAGGAAGGAG
1060 1070 1080 1090 1100
SAAGVAGGVV LPQQQQQQQQ QQQQQGQQPL QSCIHPSISP MGGVMPPQQL
1110 1120 1130 1140 1150
RPQGPPGILG QQTAAGLGVG VGVTNNMVTM RSHSPGGNML ALQQQQRMQF
1160 1170 1180 1190 1200
PQQQQQQPPG SGAGKMLVGP PGPSPGGMVV NPALSPYQTT NVLTSPVPGQ
1210 1220 1230 1240 1250
QQQQQFINAN GGTGANPQLS EIMKQRHIHQ QQQQQQQQQQ QQGMLLPQSP
1260 1270 1280 1290 1300
FSNSTPLQQQ QQQQQQQQQQ QATSNSFSSP MQQQQQGQQQ QQQKPGSVLN
1310 1320 1330 1340 1350
NMPPTPTSLE ALNAGAGAPG TGGSASNVTV SAPSPSPGFL SNGPSIGTPS
1360 1370 1380 1390 1400
NNNNSSSANN NPPSVSSLMQ QPLSNRPGTP PYIPASPVPA TSASGLAASS
1410 1420 1430 1440 1450
TPASAAATCA SSGSGSNSSS GATAAGASST SSSSSAGSGT PLSSVSTPTS
1460 1470 1480 1490 1500
ATMATSSGGG GGGGGNAGGG SSTTPASNPL LLMSGGTAGG GTGATTTTST
1510 1520 1530 1540 1550
SSSSRMMSSS SSLSSQMAAL EAAARDNDDE TPSPSGENTN GSGGSGNAGG
1560 1570 1580 1590 1600
MASKGKLDSI KQDDDIKKEF MDDSCGGNND SSQMDCSTGG GKGKNVNNDG
1610 1620 1630 1640 1650
TSMIKMEIKT EDGLDGEVKI KTEAMDVDEA GGSTAGEHHG EGGGGSGVGG
1660 1670 1680 1690 1700
GKDNINGAHD GGATGGAVDI KPKTETKPLV PEPLAPNAGD KKKKCQFNPE
1710 1720 1730 1740 1750
ELRTALLPTL EKLYRQEPES VPFRYPVDPQ ALGIPDYFEI VKKPMDLGTI
1760 1770 1780 1790 1800
RTNIQNGKYS DPWEYVDDVW LMFDNAWLYN PKTSRVYRYC TKLSEVFEAE
1810 1820 1830 1840 1850
IDPVMQALGY CCGRKYTFNP QVLCCYGKQL CTIPRDAKYY SYQNSLKEYG
1860 1870 1880 1890 1900
VASNRYTYCQ KCFNDIQGDT VTLGDDPLQS QTQIKKDQFK EMKNDHLELE
1910 1920 1930 1940 1950
PFVNCQECGR KQHQICVLWL DSIWPGGFVC DNCLKKKNSK RKENKFNAKR
1960 1970 1980 1990 2000
LPTTKLGVYI ETRVNNFLKK KEAGAGEVHI RVVSSSDKCV EVKPGMRRRF
2010 2020 2030 2040 2050
VEQGEMMNEF PYRAKALFAF EEVDGIDVCF FGMHVQEYGS ECPAPNTRRV
2060 2070 2080 2090 2100
YIAYLDSVHF FRPRQYRTAV YHEILLGYMD YVKQLGYTMA HIWACPPSEG
2110 2120 2130 2140 2150
DDYIFHCHPT DQKIPKPKRL QEWYKKMLDK GMIERIIQDY KDILKQAMED
2160 2170 2180 2190 2200
KLGSAAELPY FEGDFWPNVL EESIKELDQE EEEKRKQAEA AEAAAAANLF
2210 2220 2230 2240 2250
SIEENEVSGD GKKKGQKKAK KSNKSKAAQR KNSKKSNEHQ SGNDLSTKIY
2260 2270 2280 2290 2300
ATMEKHKEVF FVIRLHSAQS AASLAPIQDP DPLLTCDLMD GRDAFLTLAR
2310 2320 2330 2340 2350
DKHFEFSSLR RAQFSTLSML YELHNQGQDK FVYTCNHCKT AVETRYHCTV
2360 2370 2380 2390 2400
CDDFDLCIVC KEKVGHQHKM EKLGFDIDDG SALADHKQAN PQEARKQSIQ
2410 2420 2430 2440 2450
RCIQSLAHAC QCRDANCRLP SCQKMKLVVQ HTKNCKRKPN GGCPICKQLI
2460 2470 2480 2490 2500
ALCCYHAKNC EEQKCPVPFC PNIKHKLKQQ QSQQKFQQQQ LLRRRVALMS
2510 2520 2530 2540 2550
RTAAPAALQG PAAVSGPTVV SGGVPVVGMS GVAVSQQVIP GQAGILPPGA
2560 2570 2580 2590 2600
GGMSPSTVAV PSPVSGGAGA GGMGGMTSPH PHQPGIGMKP GGGHSPSPNV
2610 2620 2630 2640 2650
LQVVKQVQEE AARQQVSHGG GFGKGVPMAP PVMNRPMGGA GPNQNVVNQL
2660 2670 2680 2690 2700
GGMGVGVGGV GGVGVGGVGG VGVNQLNSGG GNTPGAPISG PGMNVNHLMS
2710 2720 2730 2740 2750
MDQWGGGGAG GGGANPGGGN PQARYANNTG GMRQPTHVMQ TNLIPPQQQQ
2760 2770 2780 2790 2800
QMMGGLGGPN QLGGGQMPVG GQHGGMGMGM GAPPMAGTVG GVRPSPGAGG
2810 2820 2830 2840 2850
GGGSATGGGL NTQQLALIMQ KIKNNPTNES NQHILAILKQ NPQIMAAIIK
2860 2870 2880 2890 2900
QRQQSQNNAA AGGGAPGPGG ALQQQQAGNG PQNPQQQQQQ QQQQQVMQQQ
2910 2920 2930 2940 2950
QMQHMMNQQQ GGGGPQQMNP NQQQQQQQVN LMQQQQQGGP GGPGSGLPTR
2960 2970 2980 2990 3000
MPNMPNALGM LQSLPPNMSP GVSTQGGMVP NQNWNKMRYM QMSQYPPPYP
3010 3020 3030 3040 3050
QRQRGPHMGG AGPGPGQQQF PGGGGGAGNF NAGGAGGAGG VVGVGGVPGG
3060 3070 3080 3090 3100
AGTVPGGDQY SMANAAAASN MLQQQQGQVG VGVGVGVKPG PGQQQQQMGV
3110 3120 3130 3140 3150
GMPPGMQQQQ QQQQPLQQQQ MMQVAMPNAN AQNPSAVVGG PNAQVMVRRR
3160 3170 3180 3190
RISAAAADAI GPLVAAYSLP AANAIATFGS IATCCSIRLA
Length:3,190
Mass (Da):331,878
Last modified:July 1, 1997 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iE53526F78BC055A8
GO

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

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GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
U88570 mRNA Translation: AAB53050.1

Protein sequence database of the Protein Information Resource

More...
PIRi
T13828

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U88570 mRNA Translation: AAB53050.1
PIRiT13828

3D structure databases

Database of comparative protein structure models

More...
ModBasei
Search...

SWISS-MODEL Interactive Workspace

More...
SWISS-MODEL-Workspacei
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Protein-protein interaction databases

DIPiDIP-41329N
IntActiO01368, 2 interactors
MINTiO01368

Organism-specific databases

FlyBaseiFBgn0261617, nej

Phylogenomic databases

HOGENOMiCLU_000162_0_0_1

Enzyme and pathway databases

SignaLinkiO01368

Miscellaneous databases

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

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ChiTaRSi
nej, fly

Gene expression databases

BgeeiFBgn0261617, Expressed in female gonad and 33 other tissues
ExpressionAtlasiO01368, baseline and differential

Family and domain databases

CDDicd15802, RING_CBP-p300, 1 hit
Gene3Di1.10.246.20, 1 hit
1.20.1020.10, 2 hits
1.20.920.10, 1 hit
2.10.110.40, 1 hit
3.30.40.10, 1 hit
3.30.60.90, 1 hit
InterProiView protein in InterPro
IPR001487, Bromodomain
IPR036427, Bromodomain-like_sf
IPR018359, Bromodomain_CS
IPR031162, CBP_P300_HAT
IPR013178, Histone_AcTrfase_Rtt109/CBP
IPR003101, KIX_dom
IPR036529, KIX_dom_sf
IPR010303, RING_CBP-p300
IPR038547, RING_CBP-p300_sf
IPR035898, TAZ_dom_sf
IPR019786, Zinc_finger_PHD-type_CS
IPR013083, Znf_RING/FYVE/PHD
IPR000197, Znf_TAZ
IPR000433, Znf_ZZ
IPR043145, Znf_ZZ_sf
PfamiView protein in Pfam
PF00439, Bromodomain, 1 hit
PF06001, DUF902, 1 hit
PF08214, HAT_KAT11, 1 hit
PF02172, KIX, 1 hit
PF02135, zf-TAZ, 2 hits
PF00569, ZZ, 1 hit
PRINTSiPR00503, BROMODOMAIN
SMARTiView protein in SMART
SM00297, BROMO, 1 hit
SM01250, KAT11, 1 hit
SM00551, ZnF_TAZ, 2 hits
SM00291, ZnF_ZZ, 1 hit
SUPFAMiSSF47040, SSF47040, 1 hit
SSF47370, SSF47370, 1 hit
SSF57933, SSF57933, 2 hits
PROSITEiView protein in PROSITE
PS00633, BROMODOMAIN_1, 1 hit
PS50014, BROMODOMAIN_2, 1 hit
PS51727, CBP_P300_HAT, 1 hit
PS50952, KIX, 1 hit
PS01359, ZF_PHD_1, 1 hit
PS50134, ZF_TAZ, 2 hits
PS01357, ZF_ZZ_1, 1 hit
PS50135, ZF_ZZ_2, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

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ProtoNeti
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MobiDB: a database of protein disorder and mobility annotations

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MobiDBi
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<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiO01368_DROME
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: O01368
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: July 1, 1997
Last sequence update: July 1, 1997
Last modified: April 7, 2021
This is version 156 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)
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